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Manuscripts from 2018

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SPSNet: subpopulation-sensitive network-based analysis of heterogeneous gene expression data., Abha Belorkar, Rajanikanth Vadigepalli, and Limsoon Wong

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Monocarboxylate Transporter 4 (MCT4) Knockout Mice Have Attenuated 4NQO Induced Carcinogenesis; A Role for MCT4 in Driving Oral Squamous Cell Cancer., Sara Bisetto, Diana Whitaker Menezes, Nicole A. Wilski, Madalina Tuluc, Joseph Curry, Tingting Zhan, Christopher M. Snyder, Ubaldo E. Martinez-Outshoorn, and Nancy J. Philp

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Cellular network modeling and single cell gene expression analysis reveals novel hepatic stellate cell phenotypes controlling liver regeneration dynamics, Daniel Cook, Sirisha Achanta, Jan B. Hoek, Babatunde A. Ogunnaike, and Rajanikanth Vadigepalli

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Metformin Clinical Trial in HPV+ and HPV- Head and Neck Squamous Cell Carcinoma: Impact on Cancer Cell Apoptosis and Immune Infiltrate., Joseph M. Curry; Jennifer Johnson; Mehri Mollaee; Patrick Tassone; Dev Amin; Alexander Knops; Diana Whitaker Menezes; My Mahoney; Andrew P. South; Ulrich Rodeck; Tingting Zhan; Larry A. Harshyne; Nancy Philp; Adam J. Luginbuhl; David Cognetti; Madalina Tuluc; and Ubaldo E. Martinez-Outshoorn, MD

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Microtubule-Associated Protein 1 Light Chain 3B, (LC3B) Is Necessary to Maintain Lipid-Mediated Homeostasis in the Retinal Pigment Epithelium., Anuradha Dhingra, Brent A Bell, Neal S. Peachey, Lauren L. Daniele, Juan Reyes-Reveles, Rachel C. Sharp, Bokkyoo Jun, Nicolas G. Bazan, Janet R. Sparrow, Hye Jin Kim, Nancy J. Philp, and Kathleen Boesze-Battaglia

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Human-like hyperplastic prostate with low ZIP1 induced solely by Zn deficiency in rats., Louise Y. Fong, Ruiyan Jing, Karl J. Smalley, Zi-Xuan Wang, Cristian Taccioli, Sili Fan, Hongping Chen, Hansjuerg Alder, Kay Huebner, John L. Farber, Oliver Fiehn, and Carlo M. Croce

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Potential role of CSF cytokine profiles in discriminating infectious from non-infectious CNS disorders., Danielle Fortuna, D. Craig Hooper, Amity L. Roberts, Larry A. Harshyne, Michelle Nagurney, and Mark T. curtis

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Recurrent hotspot mutations in HRAS Q61 and PI3K-AKT pathway genes as drivers of breast adenomyoepitheliomas., Felipe C. Geyer, Anqi Li, Anastasios D. Papanastasiou, Alison Smith, Pier Selenica, Kathleen A. Burke, Marcia Edelweiss, Huei-Chi Wen, Salvatore Piscuoglio, Anne M. Schultheis, Luciano G. Martelotto, Fresia Pareja, Rahul Kumar, Alissa Brandes, Dan Fan, Thais Basili, Arnaud Da Cruz Paula, John R. Lozada, Pedro Blecua, Simone Muenst, Achim A. Jungbluth, Maria P. Foschini, Hannah Y. Wen, Edi Brogi, Juan P. Palazzo, Brian P. Rubin, Charlotte K.Y. Ng, Larry Norton, Zsuzsanna Varga, Ian O. Ellis, Emad A. Rakha, Sarat Chandarlapaty, Britta Weigelt, and Jorge S. Reis-Filho

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Metabolic reprogramming of murine cardiomyocytes during autophagy requires the extracellular nutrient sensor decorin., Maria A. Gubbiotti, Erin L. Seifert, Ulrich Rodeck, Jan B. Hoek, and Renato V. Iozzo

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Phosphaturic mesenchymal tumor of the nasal cavity: Clinicopathologic correlation is essential for diagnosis, Aidan Kerr, Ryan Rimmer, Marc Rosen, James J. Evans, Madalina Tuluc, and Stacey K. Mardekian

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Bacterial contamination of platelets for transfusion: strategies for prevention., Jerrold H. Levy, Matthew D. Neal, and Jay H. Herman

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Credibility, Replicability, and Reproducibility in Simulation for Biomedicine and Clinical Applications in Neuroscience., Lealem Mulugeta, Andrew Drach, Ahmet Erdemir, C A Hunt, Marc Horner, Joy P. Ku, Jerry G Myers, Rajanikanth Vadigepalli, and William W. Lytton

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Mitochondrial fusion and Bid-mediated mitochondrial apoptosis are perturbed by alcohol with distinct dependence on its metabolism, Shamim Naghdi, William S. Slovinsky, Muniswamy Madesh, Emanual Rubin, and György Hajnóczky

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Endorepellin remodels the endothelial transcriptome toward a pro-autophagic and pro-mitophagic gene signature., Thomas Neill, Eva Andreuzzi, Zi-Xuan Wang, Stephen C. Peiper, Maurizo Mongiat, and Renato V. Iozzo

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Loss-of-function mutations in ATP6AP1 and ATP6AP2 in granular cell tumors., Fresia Pareja, Alissa H. Brandes, Thais Basili, Pier Selenica, Felipe C. Geyer, Dan Fan, Arnaud Da Cruz Paula, Rahul Kumar, David N. Brown, Rodrigo Gularte-Mérida, Barbara Alemar, Rui Bi, Raymond S. Lim, Ino de Bruijn, Sho Fujisawa, Rui Gardner, Elvin Feng, Anqi Li, Edaise M. da Silva, John R. Lozada, Pedro Blecua, Leona Cohen-Gould, Achim A. Jungbluth, Emad A. Rakha, Ian O. Ellis, Maria I.A. Edelweiss, Juan P. Palazzo, Larry Norton, Travis Hollmann, Marcia Edelweiss, Brian P. Rubin, Britta Weigelt, and Jorge S. Reis-Filho

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Antimicrobial peptide LL-37 and recombinant human mannose-binding lectin express distinct age- and pathogen-specific antimicrobial activity in human newborn cord blood in vitro, Annette Scheid, Ning Li, Carleen Jeffers, Francesco Borriello, Sweta Joshi, Al Ozonoff, Matthew Pettengill, and Ofer Levy

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Sex-dependent effects of developmental lead exposure on the brain, Garima Singh, Vikrant Singh, Marissa Sobolewski, Deborah A. Cory-Slechta, and Jay S. Schneider

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Different Behavioral Experiences Produce Distinctive Parallel Changes in, and Correlate With, Frontal Cortex and Hippocampal Global Post-translational Histone Levels., Marissa Sobolewski, Garima Singh, Jay S. Schneider, and Deborah A. Cory-Slechta

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Synchronous gastric and duodenal metastases from head and neck squamous cell carcinoma: a unique presentation of upper gastrointestinal bleeding., Nicholas P. Tarangelo, Charles Andrew Kistler, Zachary Daitch, Wei Jiang, and Daniel M. Quirk

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Neuroprotective Role of Phytochemicals., Bharath Kumar Velmurugan, Baskaran Rathinasamy, Bharathi Priya Lohanathan, Varadharajan Thiyagarajan, and Ching-Feng Weng

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Causality Analysis and Cell Network Modeling of Spatial Calcium Signaling Patterns in Liver Lobules., Aalap Verma, Anil Noronha Antony, Babatunde A. Ogunnaike, Jan B. Hoek, and Rajanikanth Vadigepalli

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Modeling the dynamics of human liver failure post liver resection, Babita Verma, Pushpavanam Subramaniam, and Rajanikanth Vadigepalli

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In wound repair vimentin mediates the transition of mesenchymal leader cells to a myofibroblast phenotype., J. L. Walker, B. M. Bleaken, A. R. Romisher, A. A. Alnwibit, and A. S. Menko

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Epidemiology of moderate alcohol consumption and breast cancer: Association or causation?, Samir Zakhari and Jan B. Hoek

Manuscripts from 2017

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Novel Influences of IL-10 on CNS Inflammation Revealed by Integrated Analyses of Cytokine Networks and Microglial Morphology., Warren D. Anderson, Andrew D. Greenhalgh, Aditya Takwale, Samuel David, and Rajanikanth Vadigepalli

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Intracellular Ca 2+ sensing: role in calcium homeostasis and signaling, Rafaela Bagur and György Hajnóczky

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Life After Being a Pathology Department Chair II: Lessons Learned., David N. Bailey, Mary F. Lipscomb, Fred Gorstein, David Wilkinson, and Fred Sanfilippo

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A simple and accurate rule-based modeling framework for simulation of autocrine/paracrine stimulation of glioblastoma cell motility and proliferation by L1CAM in 2-D culture., Justin Caccavale, David Fiumara, Michael Stapf, Liedeke Sweitzer, Hannah J. Anderson, Jonathan Gorky, Prasad Dhurjati, and Deni S. Galileo

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Microscopic Examination of Findings Encountered during Cadaver Dissection: Malignant, Benign or Anatomic Variation?, Maria Cicioni, Vandi Ly, Guiyun Zhang, and Bruce Fenderson

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ROS Control Mitochondrial Motility through p38 and the Motor Adaptor Miro/Trak., Valentina Debattisti, Akos A. Gerencser, Masao Saotome, Sudipto Das, and György Hajnóczky

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Integration of metabolomics, transcriptomics, and microRNA expression profiling reveals a miR-143-HK2-glucose network underlying zinc-deficiency-associated esophageal neoplasia, Louise Y. Fong, Ruiyan Jing, Karl Smalley, Cristian Taccioli, Johannes Fahrmann, Dinesh K. Barupal, Hansjuerg Alder, John L. Farber, Oliver Fiehn, and Carlo M. Croce

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Intratumoral heterogeneity analysis reveals hidden associations between protein expression losses and patient survival in clear cell renal cell carcinoma., Wei Jiang, Essel Dulaimi, Karthik Devarajan, Theodore Parsons, Qiong Wang, Raymond O'Neill, Charalambos C. Solomides, Stephen C. Peiper, Joseph R. Testa, Robert Uzzo, and Haifeng Yang

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Association of metabolic syndrome and change in Unified Parkinson's Disease Rating Scale scores., Maureen Leehey, Sheng Luo, Saloni Sharma, Anne-Marie A. Wills, Jacquelyn L. Bainbridge, Pei Shieen Wong, David K. Simon, Jay S Schneider, Yunxi Zhang, Adriana Pérez, Rohit Dhall, Chadwick W. Christine, Carlos Singer, Franca Cambi, and James T Boyd

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Induction of Immune Surveillance of the Dysmorphogenic Lens., Caitlin M. Logan, Caitlin J. Bowen, and A. Sue Menko

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Idiopathic nodular glomerulosclerosis in a chronic marijuana user; a case report and review of the literature, Mehri Mollaee, Tibor Fülöp, Sohil Abdul Salim, and Seyed Mehrdad Hamrahian

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Decorin-evoked paternally expressed gene 3 (PEG3) is an upstream regulator of the transcription factor EB (TFEB) in endothelial cell autophagy., Thomas Neill, Catherine Sharpe, Rick T. Owens, and Renato V. Iozzo

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Tissue-Specific Mitochondrial Decoding of Cytoplasmic Ca(2+) Signals Is Controlled by the Stoichiometry of MICU1/2 and MCU., Melanie Paillard, György Csordás, Gergö Szanda, Tünde Golenár, Valentina Debattisti, Adam Bartok, Nadan Wang, Cynthia Moffat, Erin L. Seifert, András Spät, and György Hajnóczky

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Proteoglycan neofunctions: regulation of inflammation and autophagy in cancer biology., Liliana Schaefer, Claudia Tredup, Maria A. Gubbiotti, and Renato V. Iozzo

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Strain specific effects of low level lead exposure on associative learning and memory in rats., Megha Verma and J. S. Schneider

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Posttranscriptional Upregulation of IDH1 by HuR Establishes a Powerful Survival Phenotype in Pancreatic Cancer Cells., Mahsa Zarei, Shruti Lal, Seth J. Parker, Avinoam Nevler, Ali Vaziri-Gohar, Katerina Dukleska, Nicole C. Mambelli-Lisboa, Cynthia Moffat, Fernando F Blanco, Saswati N. Chand, Masaya Jimbo, Joseph A. Cozzitorto, Wei Jiang, Charles J. Yeo, Eric R. Londin, Erin L. Seifert, Christian M. Metallo, Jonathan R. Brody, and Jordan M. Winter

Manuscripts from 2016

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MICU1 regulation of mitochondrial Ca(2+) uptake dictates survival and tissue regeneration., Anil Noronha Antony; Melanie Paillard; Cynthia Moffat; Egle Juskeviciute; Jason Correnti; Brad Bolon; Emanual Rubin, MD; György Csordás; Erin L Seifert; Jan B. Hoek; and György Hajnóczky

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Bilateral triad of persistent median artery, a bifid median nerve and high origin of its palmar cutaneous branch. A case report and clinical implications, Olutayo Ariyo and John Shea

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Cells activated for wound repair have the potential to direct collective invasion of an epithelium., Brigid M Bleaken, A Sue Menko, and Janice Walker

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Integrated live imaging and molecular profiling of embryoid bodies reveals a synchronized progression of early differentiation., Jonathan Boxman, Naor Sagy, Sirisha Achanta, Rajanikanth Vadigepalli, and Iftach Nachman

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Suppression of progranulin expression inhibits bladder cancer growth and sensitizes cancer cells to cisplatin., Simone Buraschi, Shi-Qiong Xu, Manuela Stefanello, Igor Moskalev, Alaide Morcavallo, Marco Genua, Ryuta Tanimoto, Ruth Birbe, Stephen C. Peiper, Leonard G. Gomella, Antonino Belfiore, Peter C. Black, Renato V. Iozzo, and Andrea Morrione

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The structure and regulation of Cullin 2 based E3 ubiquitin ligases and their biological functions., Weijia Cai and Haifeng Yang

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MicroRNA dysregulation and esophageal cancer development depend on the extent of zinc dietary deficiency., Louise Fong, Cristian Taccioli, Ruiyan Jing, Karl Smalley, Hansjuerg Alder, Yubao Jiang, Paolo Fadda, John Farber, and Carlo M Croce

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Zinc intake, microRNA dysregulation, and esophageal cancer., Louise Y. Fong, John Farber, and Carlo M. Croce

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Multiplatform molecular profiling identifies potentially targetable biomarkers in malignant phyllodes tumors of the breast., Zoran Gatalica, Semir Vranic, Anatole Ghazalpour, Joanne Xiu, Idris Tolgay Ocal, John McGill, Ryan P Bender, Erin Discianno, Aaron Schlum, Souzan Sanati, Juan P. Palazzo, Sandeep Reddy, and Barbara Pockaj

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Estrogen regulates miRNA expression: implication of estrogen receptor and miR-124/AKT2 in tumor growth and angiogenesis., Cheng-Fei Jiang, Dong-Mei Li, Zhu-Mei Shi, Lin Wang, Min-Min Liu, Xin Ge, Xue Liu, Ying-Chen Qian, Yi-Yang Wen, Lin-Lin Zhen, Jie Lin, Ling-Zhi Liu, and Bing-Hua Jiang

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Immunohistochemistry Successfully Uncovers Intratumoral Heterogeneity and Widespread Co-Losses of Chromatin Regulators in Clear Cell Renal Cell Carcinoma., Wei Jiang, Essel Dulaimi, Karthik Devarajan, Theodore Parsons, Qiong Wang, Lili Liao, Eun-Ah Cho, Raymond O'Neill, Charalambos C. Solomides, Stephen C. Peiper, Joseph R Testa, Robert Uzzo, and Haifeng Yang

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Unique metabolic features of pancreatic cancer stroma: relevance to the tumor compartment, prognosis, and invasive potential., Erik S. Knudsen, Uthra Balaji, Elizaveta Freinkman, Peter McCue, and Agnieszka K. Witkiewicz

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A novel comparative pattern analysis approach identifies chronic alcohol mediated dysregulation of transcriptomic dynamics during liver regeneration., Lakshmi Kuttippurathu, Egle Juskeviciute, Rachael P Dippold, Jan B. Hoek, and Rajanikanth Vadigepalli

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MiRNA-145 increases therapeutic sensibility to gemcitabine treatment of pancreatic adenocarcinoma cells., Yong Lin, Xin Ge, Yiyang Wen, Zhu-Mei Shi, Qiu-Dan Chen, Min Wang, Ling-Zhi Liu, Bing-Hua Jiang, and Yuan Lu

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Ductal carcinoma in situ of the breast: the importance of morphologic and molecular interactions., Stacey K. Mardekian, Alessandro Bombonati, and Juan P. Palazzo

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New Insight Into the Protrusions and Paddles That Link Lens Fiber Cells., Sue Menko

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EphA2 is a functional receptor for the growth factor progranulin., Thomas Neill, Simone Buraschi, Atul Goyal, Catherine Sharpe, Elizabeth Natkanski, Liliana Schaefer, Andrea Morrione, and Renato V. Iozzo

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Decorin as a multivalent therapeutic agent against cancer., Thomas Neill, Liliana Schaefer, and Renato V. Iozzo

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Single-Cell Transcriptional Analysis Reveals Novel Neuronal Phenotypes and Interaction Networks Involved in the Central Circadian Clock., James Park, Haisun Zhu, Sean O'Sullivan, Babatunde A Ogunnaike, David R Weaver, James S. Schwaber, and Rajanikanth Vadigepalli

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Deficiency of Mkrn2 causes abnormal spermiogenesis and spermiation, and impairs male fertility., Xu Qian, Lin Wang, Bo Zheng, Zhu-Mei Shi, Xin Ge, Cheng-Fei Jiang, Ying-Chen Qian, Dong-Mei Li, Wei Li, Xue Liu, Yu Yin, Ji-Tai Zheng, Hua Shen, Min Wang, Xue-Jiang Guo, Jun He, Marie Lin, Ling-Zhi Liu, Jia-Hao Sha, and Bing-Hua Jiang

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Natural and Induced Mitochondrial Phosphate Carrier Loss: DIFFERENTIAL DEPENDENCE OF MITOCHONDRIAL METABOLISM AND DYNAMICS AND CELL SURVIVAL ON THE EXTENT OF DEPLETION., Erin L. Seifert, Aniko Gál, Michelle G. Acoba, Qipei Li, Lauren Anderson-Pullinger, Tünde Golenár, Cynthia Moffat, Neal Sondheimer, Steven M. Claypool, and György Hajnóczky

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Reduction in squamous cell carcinomas in mouse skin by dietary zinc supplementation., Jin Sun, Rulong Shen, Morgan S. Schrock, James Liu, Xueliang Pan, Donald Quimby, Nicola Zanesi, Teresa Druck, Louise Y. Fong, and Kay Huebner

Manuscripts from 2015

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Assessment for Risk Factors Associated with Local Recurrence in Chordoma, John A. Abraham, MD and Wei Jiang, MD, PhD

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Bordetella petrii recovered from chronic pansinusitis in an adult with cystic fibrosis, Laura Biederman; Marc Rosen MD; Brent S. Bobik; and Amity L. Roberts, PhD, D(ABMM)

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Disseminated histiocytoses biomarkers beyond BRAFV600E: frequent expression of PD-L1., Nurija Bilalovic, Juan P. Palazzo, Ryan P Bender, Jeffrey Swensen, Sherri Z Millis, Semir Vranic, Daniel Von Hoff, Robert J Arceci, and Zoran Gatalica

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Strategic distribution of the mitochondrial Ca2+ uniporter in cardiac mitochondria, Sergio De La Fuente, Caitlin Vail, Elorm J. Agra, Kira Holmstrom, Junhui Sun, Jyotsna Mishra, Toren Finkel, Elizabeth Murphy, Shey-Shing Sheu, and György Csordás

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Compensatory fetal membrane mechanisms between biglycan and decorin in inflammation., Luciana Batalha de Miranda de Araujo, Casie E Horgan, Abraham Aron, Renato V. Iozzo, and Beatrice E Lechner

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The role of perlecan and endorepellin in the control of tumor angiogenesis and endothelial cell autophagy., Stephen Douglass, Atul Goyal, and Renato V. Iozzo

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Achilles tendons from decorin- and biglycan-null mouse models have inferior mechanical and structural properties predicted by an image-based empirical damage model., Joshua A. Gordon, Benjamin R. Freedman, Andrey Zuskov, Renato V. Iozzo, David E. Birk, and Louis J. Soslowsky

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An Assessment of the Reliability of Platelet-Associated Flags Generated by the Sysmex XE-5000 Automated Hematology Analyzer in Detecting Platelet Clumps, Jennifer M. Hawkins, DO; Gene Gulati, Ph.D; Guldeep Uppal, MD; and Jerald Z. Gong, MD

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Cosmetics for the matrix: An attractive new style for Matrix Biology., Renato V. Iozzo and Thomas Neill

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Phylogenetic Tree Construction and “Truncal Loss” Analysis Reveal Hidden Associations Between Loss of Protein Expression in SWI/SNF Complex Components and Tumor Stage and Survival in Clear Cell Renal Cell Carcinoma (CCRCC), Wei Jiang, MD, PhD; Essel Dulaimi; Karthik Devarajan; Qiong Wang; Raymond O'Neill; Charalambos C. Solomides, MD; Stephen C Peiper, PhD; Robert Uzzo; Joseph R. Testa; and Haifeng Yang, PhD

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Loss of Expression of SWI/SNF Chromatin Remodeling Complex Components and SETD2 are Heterogeneous, Widespread, and Co-Occur in Clear Cell Renal Cell Carcinoma, Wei Jiang, MD, PhD; Essel Dulaimi; Theodore Parsons; Qiong Wang; Karthik Devarajan; Raymond O'Neill; Charalambos C. Solomides, MD; Stephen C Peiper, PhD; Jospeh R. Testa; Robert Uzzo; and Haifeng Yang

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Gliopathy of Demyelinating and Non-Demyelinating Strains of Mouse Hepatitis Virus., Lawrence C. Kenyon, Kaushiki Biswas, Kenneth S Shindler, Manasi Nabar, Marjorie Stout, Susan T Hingley, Judith B Grinspan, and Jayasri Das Sarma

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t(3;8)(q26;q24) with MYC Rearrangement in Acute Myeloid Leukemia: A Case Report, Vandi Ly, MD; Renu Bajaj, PhD; Jerald Z. Gong, MD; Zi-Xuan Wang, PhD; Stephen C Peiper, MD; and Guldeep Uppal, MD

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Intracellular Information Processing through Encoding and Decoding of Dynamic Signaling Features., Hirenkumar K Makadia, James S. Schwaber, and Rajanikanth Vadigepalli

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Computational modeling analysis of mitochondrial superoxide production under varying substrate conditions and upon inhibition of different segments of the electron transport chain., Nikolai I. Markevich and Jan B. Hoek

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Desmin common mutation is associated with multi-systemic disease manifestations and depletion of mitochondria and mitochondrial DNA., Elizabeth M. McCormick, Lawrence C. Kenyon, and Marni J. Falk

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Motifs of VDAC2 required for mitochondrial Bak import and tBid-induced apoptosis., Shamim Naghdi, Péter Várnai, and György Hajnóczky

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Low Level Lead Exposure Impairs Attentional Set Shifting Task Performance Depending upon Sex and Developmental Periods of Exposure, L.S. Neuwirth, D.W. Anderson, and J. S. Schneider

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Relationship between Motor Symptoms, Cognition, and Demographic Characteristics in Treated Mild/Moderate Parkinson's Disease., Jay S Schneider, Stephanie Sendek, and Chengwu Yang

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Intraventricular Sialidase Administration Enhances GM1 Ganglioside Expression and Is Partially Neuroprotective in a Mouse Model of Parkinson's Disease., Jay S Schneider, Thomas N Seyfried, Hyo-S Choi, and Sarah Kidd

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Effects of chronic manganese exposure on attention and working memory in non-human primates., Jay S. Schneider, Charles Williams, Mark Ault, and Tomás R. Guilarte

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Mitochondrial Ca(2+) uptake by the voltage-dependent anion channel 2 regulates cardiac rhythmicity., Hirohito Shimizu, Johann Schredelseker, Jie Huang, Kui Lu, Shamim Naghdi, Fei Lu, Sarah Franklin, Hannah Dg Fiji, Kevin Wang, Huanqi Zhu, Cheng Tian, Billy Lin, Haruko Nakano, Amy Ehrlich, Junichi Nakai, Adam Z Stieg, James K Gimzewski, Atsushi Nakano, Joshua I. Goldhaber, Thomas M. Vondriska, György Hajnóczky, Ohyun Kwon, and Jau-Nian Chen

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Caffeine and Progression of Parkinson Disease: A Deleterious Interaction With Creatine., David K. Simon, Cai Wu, Barbara C. Tilley, Anne-Marie Wills, Michael J. Aminoff, Jacquelyn Bainbridge, Robert A. Hauser, Jay S. Schneider, Saloni Sharma, Carlos Singer, Caroline M. Tanner, Daniel Truong, and Pei Shieen Wong

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Repression of Esophageal Neoplasia and Inflammatory Signaling by Anti-miR-31 Delivery In Vivo., Cristian Taccioli, Michela Garofalo, Hongping Chen, Yubao Jiang, Guidantonio Malagoli Tagliazucchi, Gianpiero Di Leva, Hansjuerg Alder, Paolo Fadda, Justin Middleton, Karl J. Smalley, Tommaso Selmi, Srivatsava Naidu, John L. Farber, Carlo M. Croce, and Louise Fong

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SLIT2/ROBO1-miR-218-1-RET/PLAG1: a new disease pathway involved in Hirschsprung's disease., Weibing Tang, Junwei Tang, Jun He, Zhigang Zhou, Yufeng Qin, Jingjing Qin, Bo Li, Xiaoqun Xu, Qiming Geng, Weiwei Jiang, Wei Wu, Xinru Wang, and Yankai Xia

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Age-related EBV-associated Lymphoproliferative Disorder with Widespread Gastrointestinal Involvement and Subsequent Development of T-cell Lymphoma, Guldeep Uppal, MD; Alaina Chodoff, MSII; Zi-Xuan Wang, PhD; Jeffrey P. Baliff MD; and Jerald Z. Gong, MD

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Selective impact of CDK4/6 suppression on patient-derived models of pancreatic cancer., Agnieszka K Witkiewicz; Nicholas A Borja; Jorge Franco; Jonathan Brody, MD; Charles Yeo; John Mansour; Michael A Choti; Peter McCue; and Erik S Knudsen

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MiR-497 decreases cisplatin resistance in ovarian cancer cells by targeting mTOR/P70S6K1., Shaohua Xu, Guang-Bo Fu, Zhen Tao, Jun OuYang, Fanfei Kong, Bing-Hua Jiang, Xiaoping Wan, and Ke Chen

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Pathology Encountered during Cadaver Dissection Provides an Opportunity for Integrated Learning and Critical Thinking, Guiyan Zhang and Bruce Fenderson

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GSK-3β regulates tumor growth and angiogenesis in human glioma cells., Peng Zhao, Qi Li, Zhumei Shi, Charlie Li, Lin Wang, Xue Liu, Chengfei Jiang, Xu Qian, Yongping You, Ning Liu, Ling-Zhi Liu, Lianshu Ding, and Bing-Hua Jiang

Manuscripts from 2014

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Network analysis of circular permutations in multidomain proteins reveals functional linkages for uncharacterized proteins., Donald Adjeroh, Yue Jiang, Bing-Hua Jiang, and Jie Lin

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Isoform- and species-specific control of inositol 1,4,5-trisphosphate (IP3) receptors by reactive oxygen species., Száva Bánsághi, Tünde Golenár, Muniswamy Madesh, György Csordás, Satish P. RamachandraRao, Kumar Sharma, David I Yule, Suresh K Joseph, and György Hajnóczky

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A comparison of the WHO 2004 and 2010 classification systems in pancreatic neuroendocrine tumors (Pancreatic NET), James P. Casey, MD; Aakanksha Asija, MD; Anthony J. Prestipino, M.D.; Jocelyn A. Sendecki, MD; Jonathan Brody, MD; Harish Lavu, MD; Jordan M. Winter, MD; Charles Yeo, MD; Ashwin R. Sama, MD; and Madhaven V. Pillai, MD

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Mouse hepatitis virus infection upregulates genes involved in innate immune responses., Dhriti Chatterjee, Sankar Addya, Reas S Khan, Lawrence C. Kenyon, Alexander Choe, Randall J Cohrs, Kenneth S Shindler, and Jayasri Das Sarma

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Differentiation state-specific mitochondrial dynamic regulatory networks are revealed by global transcriptional analysis of the developing chicken lens., Daniel Chauss, Subhasree Basu, Suren Rajakaruna, Zhiwei Ma, Victoria Gau, Sara Anastas, Lisa A. Brennan, J. Fielding Hejtmancik, A. Sue Menko, and Marc Kantorow

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Hormone-induced calcium oscillations depend on cross-coupling with inositol 1,4,5-trisphosphate oscillations., Lawrence D Gaspers, Paula J Bartlett, Antonio Politi, Paul Burnett, Walson Metzger, Jane Johnston, Suresh K Joseph, Thomas Höfer, and Andrew P Thomas

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Chronic Arsenic Exposure and Angiogenesis in Human Bronchial Epithelial Cells via the ROS/miR-199a-5p/HIF-1α/COX-2 Pathway., Jun He, Min Wang, Yue Jiang, Qiudan Chen, Shaohua Xu, Qing Xu, Bing-Hua Jiang, and Ling-Zhi Liu

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Seeing Is Believing: Optical Computed Tomography (OCT) and Histologic Analysis To Define Pathophysiology Of “Very”, Very Late Stent Thrombosis Occurring More Than 7 Years After Drug Eluting Stent Implantation, Antony G. Kaliyadan, MD; Alec Vishnevsky, MD; Henry Siu, MD; David Fishman, MD; John Farber, MD; Nicholas Ruggiero II, MD; and Michael P. Savage, MD