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Manuscripts from 2016

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MICU1 regulation of mitochondrial Ca(2+) uptake dictates survival and tissue regeneration., Anil Noronha Antony; Melanie Paillard; Cynthia Moffat; Egle Juskeviciute; Jason Correnti; Brad Bolon; Emanual Rubin, MD; György Csordás; Erin L Seifert; Jan B. Hoek; and György Hajnóczky

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Bilateral triad of persistent median artery, a bifid median nerve and high origin of its palmar cutaneous branch. A case report and clinical implications, Olutayo Ariyo and John Shea

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Cells activated for wound repair have the potential to direct collective invasion of an epithelium., Brigid M Bleaken, A Sue Menko, and Janice Walker

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Integrated live imaging and molecular profiling of embryoid bodies reveals a synchronized progression of early differentiation., Jonathan Boxman, Naor Sagy, Sirisha Achanta, Rajanikanth Vadigepalli, and Iftach Nachman

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Suppression of progranulin expression inhibits bladder cancer growth and sensitizes cancer cells to cisplatin., Simone Buraschi, Shi-Qiong Xu, Manuela Stefanello, Igor Moskalev, Alaide Morcavallo, Marco Genua, Ryuta Tanimoto, Ruth Birbe, Stephen C. Peiper, Leonard G. Gomella, Antonino Belfiore, Peter C. Black, Renato V. Iozzo, and Andrea Morrione

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The structure and regulation of Cullin 2 based E3 ubiquitin ligases and their biological functions., Weijia Cai and Haifeng Yang

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MicroRNA dysregulation and esophageal cancer development depend on the extent of zinc dietary deficiency., Louise Fong, Cristian Taccioli, Ruiyan Jing, Karl Smalley, Hansjuerg Alder, Yubao Jiang, Paolo Fadda, John Farber, and Carlo M Croce

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Zinc intake, microRNA dysregulation, and esophageal cancer., Louise Y. Fong, John Farber, and Carlo M. Croce

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Multiplatform molecular profiling identifies potentially targetable biomarkers in malignant phyllodes tumors of the breast., Zoran Gatalica, Semir Vranic, Anatole Ghazalpour, Joanne Xiu, Idris Tolgay Ocal, John McGill, Ryan P Bender, Erin Discianno, Aaron Schlum, Souzan Sanati, Juan P. Palazzo, Sandeep Reddy, and Barbara Pockaj

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Estrogen regulates miRNA expression: implication of estrogen receptor and miR-124/AKT2 in tumor growth and angiogenesis., Cheng-Fei Jiang, Dong-Mei Li, Zhu-Mei Shi, Lin Wang, Min-Min Liu, Xin Ge, Xue Liu, Ying-Chen Qian, Yi-Yang Wen, Lin-Lin Zhen, Jie Lin, Ling-Zhi Liu, and Bing-Hua Jiang

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Immunohistochemistry Successfully Uncovers Intratumoral Heterogeneity and Widespread Co-Losses of Chromatin Regulators in Clear Cell Renal Cell Carcinoma., Wei Jiang, Essel Dulaimi, Karthik Devarajan, Theodore Parsons, Qiong Wang, Lili Liao, Eun-Ah Cho, Raymond O'Neill, Charalambos C. Solomides, Stephen C. Peiper, Joseph R Testa, Robert Uzzo, and Haifeng Yang

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Unique metabolic features of pancreatic cancer stroma: relevance to the tumor compartment, prognosis, and invasive potential., Erik S. Knudsen, Uthra Balaji, Elizaveta Freinkman, Peter McCue, and Agnieszka K. Witkiewicz

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A novel comparative pattern analysis approach identifies chronic alcohol mediated dysregulation of transcriptomic dynamics during liver regeneration., Lakshmi Kuttippurathu, Egle Juskeviciute, Rachael P Dippold, Jan B. Hoek, and Rajanikanth Vadigepalli

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MiRNA-145 increases therapeutic sensibility to gemcitabine treatment of pancreatic adenocarcinoma cells., Yong Lin, Xin Ge, Yiyang Wen, Zhu-Mei Shi, Qiu-Dan Chen, Min Wang, Ling-Zhi Liu, Bing-Hua Jiang, and Yuan Lu

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Ductal carcinoma in situ of the breast: the importance of morphologic and molecular interactions., Stacey K. Mardekian, Alessandro Bombonati, and Juan P. Palazzo

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New Insight Into the Protrusions and Paddles That Link Lens Fiber Cells., Sue Menko

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EphA2 is a functional receptor for the growth factor progranulin., Thomas Neill, Simone Buraschi, Atul Goyal, Catherine Sharpe, Elizabeth Natkanski, Liliana Schaefer, Andrea Morrione, and Renato V. Iozzo

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Decorin as a multivalent therapeutic agent against cancer., Thomas Neill, Liliana Schaefer, and Renato V. Iozzo

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Single-Cell Transcriptional Analysis Reveals Novel Neuronal Phenotypes and Interaction Networks Involved in the Central Circadian Clock., James Park, Haisun Zhu, Sean O'Sullivan, Babatunde A Ogunnaike, David R Weaver, James S. Schwaber, and Rajanikanth Vadigepalli

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Deficiency of Mkrn2 causes abnormal spermiogenesis and spermiation, and impairs male fertility., Xu Qian, Lin Wang, Bo Zheng, Zhu-Mei Shi, Xin Ge, Cheng-Fei Jiang, Ying-Chen Qian, Dong-Mei Li, Wei Li, Xue Liu, Yu Yin, Ji-Tai Zheng, Hua Shen, Min Wang, Xue-Jiang Guo, Jun He, Marie Lin, Ling-Zhi Liu, Jia-Hao Sha, and Bing-Hua Jiang

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Natural and Induced Mitochondrial Phosphate Carrier Loss: DIFFERENTIAL DEPENDENCE OF MITOCHONDRIAL METABOLISM AND DYNAMICS AND CELL SURVIVAL ON THE EXTENT OF DEPLETION., Erin L. Seifert, Aniko Gál, Michelle G. Acoba, Qipei Li, Lauren Anderson-Pullinger, Tünde Golenár, Cynthia Moffat, Neal Sondheimer, Steven M. Claypool, and György Hajnóczky

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Reduction in squamous cell carcinomas in mouse skin by dietary zinc supplementation., Jin Sun, Rulong Shen, Morgan S. Schrock, James Liu, Xueliang Pan, Donald Quimby, Nicola Zanesi, Teresa Druck, Louise Y. Fong, and Kay Huebner

Manuscripts from 2015

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Assessment for Risk Factors Associated with Local Recurrence in Chordoma, John A. Abraham, MD and Wei Jiang, MD, PhD

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Bordetella petrii recovered from chronic pansinusitis in an adult with cystic fibrosis, Laura Biederman; Marc Rosen MD; Brent S. Bobik; and Amity L. Roberts, PhD, D(ABMM)

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Disseminated histiocytoses biomarkers beyond BRAFV600E: frequent expression of PD-L1., Nurija Bilalovic, Juan P. Palazzo, Ryan P Bender, Jeffrey Swensen, Sherri Z Millis, Semir Vranic, Daniel Von Hoff, Robert J Arceci, and Zoran Gatalica

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Strategic distribution of the mitochondrial Ca2+ uniporter in cardiac mitochondria, Sergio De La Fuente, Caitlin Vail, Elorm J. Agra, Kira Holmstrom, Junhui Sun, Jyotsna Mishra, Toren Finkel, Elizabeth Murphy, Shey-Shing Sheu, and György Csordás

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Compensatory fetal membrane mechanisms between biglycan and decorin in inflammation., Luciana Batalha de Miranda de Araujo, Casie E Horgan, Abraham Aron, Renato V. Iozzo, and Beatrice E Lechner

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The role of perlecan and endorepellin in the control of tumor angiogenesis and endothelial cell autophagy., Stephen Douglass, Atul Goyal, and Renato V. Iozzo

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Achilles tendons from decorin- and biglycan-null mouse models have inferior mechanical and structural properties predicted by an image-based empirical damage model., Joshua A. Gordon, Benjamin R. Freedman, Andrey Zuskov, Renato V. Iozzo, David E. Birk, and Louis J. Soslowsky

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An Assessment of the Reliability of Platelet-Associated Flags Generated by the Sysmex XE-5000 Automated Hematology Analyzer in Detecting Platelet Clumps, Jennifer M. Hawkins, DO; Gene Gulati, Ph.D; Guldeep Uppal, MD; and Jerald Z. Gong, MD

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Cosmetics for the matrix: An attractive new style for Matrix Biology., Renato V. Iozzo and Thomas Neill

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Phylogenetic Tree Construction and “Truncal Loss” Analysis Reveal Hidden Associations Between Loss of Protein Expression in SWI/SNF Complex Components and Tumor Stage and Survival in Clear Cell Renal Cell Carcinoma (CCRCC), Wei Jiang, MD, PhD; Essel Dulaimi; Karthik Devarajan; Qiong Wang; Raymond O'Neill; Charalambos C. Solomides, MD; Stephen C Peiper, PhD; Robert Uzzo; Joseph R. Testa; and Haifeng Yang, PhD

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Loss of Expression of SWI/SNF Chromatin Remodeling Complex Components and SETD2 are Heterogeneous, Widespread, and Co-Occur in Clear Cell Renal Cell Carcinoma, Wei Jiang, MD, PhD; Essel Dulaimi; Theodore Parsons; Qiong Wang; Karthik Devarajan; Raymond O'Neill; Charalambos C. Solomides, MD; Stephen C Peiper, PhD; Jospeh R. Testa; Robert Uzzo; and Haifeng Yang

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Gliopathy of Demyelinating and Non-Demyelinating Strains of Mouse Hepatitis Virus., Lawrence C. Kenyon, Kaushiki Biswas, Kenneth S Shindler, Manasi Nabar, Marjorie Stout, Susan T Hingley, Judith B Grinspan, and Jayasri Das Sarma

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t(3;8)(q26;q24) with MYC Rearrangement in Acute Myeloid Leukemia: A Case Report, Vandi Ly, MD; Renu Bajaj, PhD; Jerald Z. Gong, MD; Zi-Xuan Wang, PhD; Stephen C Peiper, MD; and Guldeep Uppal, MD

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Intracellular Information Processing through Encoding and Decoding of Dynamic Signaling Features., Hirenkumar K Makadia, James S. Schwaber, and Rajanikanth Vadigepalli

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Computational modeling analysis of mitochondrial superoxide production under varying substrate conditions and upon inhibition of different segments of the electron transport chain., Nikolai I. Markevich and Jan B. Hoek

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Desmin common mutation is associated with multi-systemic disease manifestations and depletion of mitochondria and mitochondrial DNA., Elizabeth M. McCormick, Lawrence C. Kenyon, and Marni J. Falk

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Motifs of VDAC2 required for mitochondrial Bak import and tBid-induced apoptosis., Shamim Naghdi, Péter Várnai, and György Hajnóczky

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Low Level Lead Exposure Impairs Attentional Set Shifting Task Performance Depending upon Sex and Developmental Periods of Exposure, L.S. Neuwirth, D.W. Anderson, and J. S. Schneider

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Relationship between Motor Symptoms, Cognition, and Demographic Characteristics in Treated Mild/Moderate Parkinson's Disease., Jay S Schneider, Stephanie Sendek, and Chengwu Yang

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Intraventricular Sialidase Administration Enhances GM1 Ganglioside Expression and Is Partially Neuroprotective in a Mouse Model of Parkinson's Disease., Jay S Schneider, Thomas N Seyfried, Hyo-S Choi, and Sarah Kidd

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Effects of chronic manganese exposure on attention and working memory in non-human primates., Jay S. Schneider, Charles Williams, Mark Ault, and Tomás R. Guilarte

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Mitochondrial Ca(2+) uptake by the voltage-dependent anion channel 2 regulates cardiac rhythmicity., Hirohito Shimizu, Johann Schredelseker, Jie Huang, Kui Lu, Shamim Naghdi, Fei Lu, Sarah Franklin, Hannah Dg Fiji, Kevin Wang, Huanqi Zhu, Cheng Tian, Billy Lin, Haruko Nakano, Amy Ehrlich, Junichi Nakai, Adam Z Stieg, James K Gimzewski, Atsushi Nakano, Joshua I. Goldhaber, Thomas M. Vondriska, György Hajnóczky, Ohyun Kwon, and Jau-Nian Chen

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Caffeine and Progression of Parkinson Disease: A Deleterious Interaction With Creatine., David K. Simon, Cai Wu, Barbara C. Tilley, Anne-Marie Wills, Michael J. Aminoff, Jacquelyn Bainbridge, Robert A. Hauser, Jay S. Schneider, Saloni Sharma, Carlos Singer, Caroline M. Tanner, Daniel Truong, and Pei Shieen Wong

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Repression of Esophageal Neoplasia and Inflammatory Signaling by Anti-miR-31 Delivery In Vivo., Cristian Taccioli, Michela Garofalo, Hongping Chen, Yubao Jiang, Guidantonio Malagoli Tagliazucchi, Gianpiero Di Leva, Hansjuerg Alder, Paolo Fadda, Justin Middleton, Karl J. Smalley, Tommaso Selmi, Srivatsava Naidu, John L. Farber, Carlo M. Croce, and Louise Fong

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SLIT2/ROBO1-miR-218-1-RET/PLAG1: a new disease pathway involved in Hirschsprung's disease., Weibing Tang, Junwei Tang, Jun He, Zhigang Zhou, Yufeng Qin, Jingjing Qin, Bo Li, Xiaoqun Xu, Qiming Geng, Weiwei Jiang, Wei Wu, Xinru Wang, and Yankai Xia

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Age-related EBV-associated Lymphoproliferative Disorder with Widespread Gastrointestinal Involvement and Subsequent Development of T-cell Lymphoma, Guldeep Uppal, MD; Alaina Chodoff, MSII; Zi-Xuan Wang, PhD; Jeffrey P. Baliff MD; and Jerald Z. Gong, MD

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Selective impact of CDK4/6 suppression on patient-derived models of pancreatic cancer., Agnieszka K Witkiewicz; Nicholas A Borja; Jorge Franco; Jonathan Brody, MD; Charles Yeo; John Mansour; Michael A Choti; Peter McCue; and Erik S Knudsen

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MiR-497 decreases cisplatin resistance in ovarian cancer cells by targeting mTOR/P70S6K1., Shaohua Xu, Guang-Bo Fu, Zhen Tao, Jun OuYang, Fanfei Kong, Bing-Hua Jiang, Xiaoping Wan, and Ke Chen

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Pathology Encountered during Cadaver Dissection Provides an Opportunity for Integrated Learning and Critical Thinking, Guiyan Zhang and Bruce Fenderson

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GSK-3β regulates tumor growth and angiogenesis in human glioma cells., Peng Zhao, Qi Li, Zhumei Shi, Charlie Li, Lin Wang, Xue Liu, Chengfei Jiang, Xu Qian, Yongping You, Ning Liu, Ling-Zhi Liu, Lianshu Ding, and Bing-Hua Jiang

Manuscripts from 2014

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Network analysis of circular permutations in multidomain proteins reveals functional linkages for uncharacterized proteins., Donald Adjeroh, Yue Jiang, Bing-Hua Jiang, and Jie Lin

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Isoform- and species-specific control of inositol 1,4,5-trisphosphate (IP3) receptors by reactive oxygen species., Száva Bánsághi, Tünde Golenár, Muniswamy Madesh, György Csordás, Satish P. RamachandraRao, Kumar Sharma, David I Yule, Suresh K Joseph, and György Hajnóczky

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A comparison of the WHO 2004 and 2010 classification systems in pancreatic neuroendocrine tumors (Pancreatic NET), James P. Casey, MD; Aakanksha Asija, MD; Anthony J. Prestipino, M.D.; Jocelyn A. Sendecki, MD; Jonathan Brody, MD; Harish Lavu, MD; Jordan M. Winter, MD; Charles Yeo, MD; Ashwin R. Sama, MD; and Madhaven V. Pillai, MD

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Mouse hepatitis virus infection upregulates genes involved in innate immune responses., Dhriti Chatterjee, Sankar Addya, Reas S Khan, Lawrence C. Kenyon, Alexander Choe, Randall J Cohrs, Kenneth S Shindler, and Jayasri Das Sarma

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Differentiation state-specific mitochondrial dynamic regulatory networks are revealed by global transcriptional analysis of the developing chicken lens., Daniel Chauss, Subhasree Basu, Suren Rajakaruna, Zhiwei Ma, Victoria Gau, Sara Anastas, Lisa A. Brennan, J. Fielding Hejtmancik, A. Sue Menko, and Marc Kantorow

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Hormone-induced calcium oscillations depend on cross-coupling with inositol 1,4,5-trisphosphate oscillations., Lawrence D Gaspers, Paula J Bartlett, Antonio Politi, Paul Burnett, Walson Metzger, Jane Johnston, Suresh K Joseph, Thomas Höfer, and Andrew P Thomas

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Chronic Arsenic Exposure and Angiogenesis in Human Bronchial Epithelial Cells via the ROS/miR-199a-5p/HIF-1α/COX-2 Pathway., Jun He, Min Wang, Yue Jiang, Qiudan Chen, Shaohua Xu, Qing Xu, Bing-Hua Jiang, and Ling-Zhi Liu

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Seeing Is Believing: Optical Computed Tomography (OCT) and Histologic Analysis To Define Pathophysiology Of “Very”, Very Late Stent Thrombosis Occurring More Than 7 Years After Drug Eluting Stent Implantation, Antony G. Kaliyadan, MD; Alec Vishnevsky, MD; Henry Siu, MD; David Fishman, MD; John Farber, MD; Nicholas Ruggiero II, MD; and Michael P. Savage, MD

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Insulin regulates glucose consumption and lactate production through reactive oxygen species and pyruvate kinase M2., Qi Li, Xue Liu, Yu Yin, Ji-Tai Zheng, Cheng-Fei Jiang, Jing Wang, Hua Shen, Chong-Yong Li, Min Wang, Ling-Zhi Liu, and Bing-Hua Jiang

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Ovarian leydig cell hyperplasia: an unusual case of virilization in a postmenopausal woman., Jaya M Mehta, Jeffery L. Miller, Anthony J. Cannon, Stacey K. Mardekian, Lawrence C. Kenyon, and Serge A. Jabbour

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Mapping of succinate dehydrogenase losses in 2258 epithelial neoplasms., Markku Miettinen, Maarit Sarlomo-Rikala, Peter McCue, Piotr Czapiewski, Renata Langfort, Piotr Waloszczyk, Krzysztof Wazny, Wojciech Biernat, Jerzy Lasota, and Zengfeng Wang

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Loss of Miro1-directed mitochondrial movement results in a novel murine model for neuron disease., Tammy T Nguyen, Sang S Oh, David Weaver, Agnieszka Lewandowska, Dane Maxfield, Max-Hinderk Schuler, Nathan K Smith, Jane Macfarlane, Gerald Saunders, Cheryl A Palmer, Valentina Debattisti, Takumi Koshiba, Stefan Pulst, Eva L Feldman, György Hajnóczky, and Janet M Shaw

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Inputs drive cell phenotype variability., James Park, Anthony Brureau, Kate Kernan, Alexandria Starks, Sonali Gulati, Babatunde Ogunnaike, James S. Schwaber, and Rajanikanth Vadigepalli

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1-Methyl-tryptophan synergizes with methotrexate to alleviate arthritis in a mouse model of arthritis., Elizabeth Pigott, James B DuHadaway, Alexander J Muller, Susan Gilmour, George C Prendergast, and Laura Mandik-Nayak

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Burkitt lymphoma in a pediatric patient with hereditary multiple exostose, Sara D. Prince; Portia A. Krieger, MD; and Andrew W. Walter, MS, MD

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Targeting fibroblast activation protein in tumor stroma with chimeric antigen receptor T cells can inhibit tumor growth and augment host immunity without severe toxicity., Liang-Chuan S. Wang; Albert Lo; John Scholler; Jing Sun; Rajrupa S. Majumdar; Veena Kapoor; Michael Antzis; Cody E. Cotner; Laura A. Johnson; Amy C. Durham; Charalambos C. Solomides, MD; Carl H. June; Ellen Puré; and Steven M. Albelda

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MiR-143 acts as a tumor suppressor by targeting N-RAS and enhances temozolomide-induced apoptosis in glioma., Lin Wang, Zhu-Mei Shi, Cheng-Fei Jiang, Xue Liu, Qiu-Dan Chen, Xu Qian, Dong-Mei Li, Xin Ge, Xie-Feng Wang, Ling-Zhi Liu, Yong-Ping You, Ning Liu, and Bing-Hua Jiang

Manuscripts from 2013

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Cis and trans regulatory mechanisms control AP2-mediated B cell receptor endocytosis via select tyrosine-based motifs., Kathleen Busman-Sahay, Lisa Drake, Anand Sitaram, Michael Marks, and James R Drake

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MICU1 Controls Both the Threshold and Cooperative Activation of the Mitochondrial Ca(2+) Uniporter., György Csordás, Tünde Golenár, Erin L Seifert, Kimberli J Kamer, Yasemin Sancak, Fabiana Perocchi, Cynthia Moffat, David Weaver, Sergio de la Fuente Perez, Roman Bogorad, Victor Koteliansky, Jeffrey Adijanto, Vamsi K Mootha, and György Hajnóczky

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Chronic ethanol feeding alters miRNA expression dynamics during liver regeneration., Rachael P Dippold, Rajanikanth Vadigepalli, Gregory E. Gonye, Biswanath Patra, and Jan B. Hoek

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Transfusion medicine illustrated: Transfusion interference by cold agglutinins., Melissa R. George and Jay Herman

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RhoB controls coordination of adult angiogenesis and lymphangiogenesis following injury by regulating VEZF1-mediated transcription., Damien Gerald, Irit Adini, Sharon Shechter, Carole Perruzzi, Joseph Varnau, Benjamin Hopkins, Shiva Kazerounian, Peter Kurschat, Stephanie Blachon, Santosh Khedkar, Mandrita Bagchi, David Sherris, George C Prendergast, Michael Klagsbrun, Heidi Stuhlmann, Alan C Rigby, Janice A Nagy, and Laura E Benjamin

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Purpose and criteria for blood smear scan, blood smear examination, and blood smear review., Gene Gulati, Jinming Song, Alina Dulau Florea, and Jerald Gong

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Different mechanisms of inflammation induced in virus and autoimmune-mediated models of multiple sclerosis in C57BL6 mice., Abhinoy Kishore, Anurag Kanaujia, Soma Nag, A M Rostami, Lawrence C. Kenyon, Kenneth S Shindler, and Jayasri Das Sarma

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Ethanol diverts early neuronal differentiation trajectory of embryonic stem cells by disrupting the balance of lineage specifiers., Rosa Sánchez-Alvarez, Saurabh Gayen, Rajanikanth Vadigepalli, and Helen Anni

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Equivalence of students' scores on timed and untimed anatomy practical examinations., Guiyan Zhang, Bruce Fenderson, Richard R Schmidt, and J J. Veloski

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The Contributions of HIF-Target Genes to Tumor Growth in RCC., Ting Zhang, Xiaohua Niu, Lili Liao, Eun-Ah Cho, and Haifeng Yang

Manuscripts from 2012

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Emergence of bimodal cell population responses from the interplay between analog single-cell signaling and protein expression noise., Marc R Birtwistle, Jens Rauch, Anatoly Kiyatkin, Edita Aksamitiene, Maciej Dobrzyński, Jan B. Hoek, Walter Kolch, Babatunde A Ogunnaike, and Boris N Kholodenko

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Decorin-mediated inhibition of colorectal cancer growth and migration is associated with E-cadherin in vitro and in mice., Xiuli Bi, Nicole M Pohl, Zhibin Qian, George R Yang, Yuan Gou, Grace Guzman, Andre Kajdacsy-Balla, Renato V Iozzo, and Wancai Yang

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A View from the Outside: Iron going to tell you a story HIF you'll listen and other horrible puns, Richard A. Brigandi, MD, PhD, FAAP

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Decorin protein core affects the global gene expression profile of the tumor microenvironment in a triple-negative orthotopic breast carcinoma xenograft model., Simone Buraschi, Thomas Neill, Rick T Owens, Leonardo A Iniguez, George Purkins, Rajanikanth Vadigepalli, Barry Evans, Liliana Schaefer, Stephen C Peiper, Zi-Xuan Wang, and Renato V Iozzo

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Temporal changes in innate immune signals in a rat model of alcohol withdrawal in emotional and cardiorespiratory homeostatic nuclei., Kate Freeman, Anthony Brureau, Rajanikanth Vadigepalli, Mary M Staehle, Melanie M Brureau, Gregory E Gonye, Jan B Hoek, D Craig Hooper, and James S Schwaber

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Proline-rich tyrosine kinase 2 (Pyk2) regulates IGF-I-induced cell motility and invasion of urothelial carcinoma cells, Marco Genua, Shi-Qiong Xu, Simone Buraschi, Stephen C. Peiper, Leonard G. Gomella, Antonio Belfiore, Renato V. Iozzo, and Andrea Morrione

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Aberrant expression of CD56 on granulocytes and monocytes in myeloproliferative neoplasm and myelodysplastic syndrome, Ping Gong, MD; Fernanco Metrebian, MD; Alina Dulau-Florea, MD; Zi-Xuan Wang, PhD; Renu Bajaj, PhD; Stephen C Peiper; and Jerald Z. Gong, MD

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Expression of Stem Cell Marker ALDH1 in Cervical Intraepithelial Neoplasia, Ping Gong and Juan Palazzo, MD

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Thomas Jefferson University, Department of Pathology, Anatomy and Cell Biology, Oral Administration of Apigenin Inhibits Metastasis through AKT/P70S6K1/MMP-9 Pathway in Orthotopic Ovarian Tumor Model., Jun He, Qing Xu, Min Wang, Chongyong Li, Xu Qian, Zhumei Shi, Ling-Zhi Liu, and Bing-Hua Jiang

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The Dermatan Sulfate Proteoglycan Decorin Modulates α2β1 Integrin and the Vimentin Intermediate Filament System during Collagen Synthesis., Oliver Jungmann, Katerina Nikolovska, Christian Stock, Jan-Niklas Schulz, Beate Eckes, Christoph Riethmüller, Rick T Owens, Renato V Iozzo, and Daniela G Seidler

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COP9 signalosome component JAB1/CSN5 is necessary for T cell signaling through LFA-1 and HIV-1 replication., Shigemi M Kinoshita, Peter O Krutzik, and Garry P Nolan

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Blood-Brain Barrier Abnormalities Caused by HIV-1 gp120: Mechanistic and Therapeutic Implications., Jean-Pierre Louboutin and David S Strayer

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Kaempferol nanoparticles achieve strong and selective inhibition of ovarian cancer cell viability., Haitao Luo, Bingbing Jiang, Bingyun Li, Zhaoliang Li, Bing-Hua Jiang, and Yi Charlie Chen

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Loss of Retinoblastoma (RB) Tumor Suppressor Expression in Breast Cancer Correlates with Better Response to Neoadjuvant Chemotherapy, Jeanne McFalls, MD; Jessica Kline, BA; Gordon Schwartz, MD, MBA, FACS; and Angieszka Witkiewicz, MD

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The metastasis suppressor KISS1 lacks antimetastatic activity in the C8161.9 xenograft model of melanoma., Jean-Marc Navenot, Barry Evans, Shinya Oishi, Shohei Setsuda, Nobutaka Fujii, and Stephen C Peiper

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Decorin antagonizes the angiogenic network: Concurrent inhibition of met, hypoxia inducible factor 1α, vascular endothelial growth factor A, and induction of thrombospondin-1 and tiMP3, Thomas Neill, Hannah Painter, Simone Buraschi, Rick T. Owens, Michael P. Lisanti, Liliana Schaefer, and Renato V. Iozzo

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Mini-Review: Decorin, a Guardian from the Matrix, Thomas Neill, Liliana Schaefer, and Renato V. Iozzo

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Knockdown of ki-67 by dicer-substrate small interfering RNA sensitizes bladder cancer cells to curcumin-induced tumor inhibition., Sivakamasundari Pichu, Swapna Krishnamoorthy, Andrei Shishkov, Bi Zhang, Peter McCue, and Biddanda C Ponnappa

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Necrostatin-1 analogues: critical issues on the specificity, activity and in vivo use in experimental disease models., N Takahashi, L Duprez, S Grootjans, A Cauwels, W Nerinckx, J B DuHadaway, V Goossens, R Roelandt, F Van Hauwermeiren, C Libert, W Declercq, N Callewaert, G C Prendergast, A Degterev, J Yuan, and P Vandenabeele

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P16/Rb Correlations in Oropharyngeal Squamous Cell Carcinoma (OSCC), Madalina Tuluc, Voichita Bar-Ad, and David Cognetti

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P53 Expression in Oropharyngeal Squamous Cell Carcinoma in Increased in HPV Positive Smokers, Madalina Tuluc, Voichita Bar-Ad, Zi-Xuan Wang, and Joseph Curry