Document Type
Article
Publication Date
9-27-2018
Abstract
Neurodegenerative diseases are normally distinguished as disorders with loss of neurons. Various compounds are being tested to treat neurodegenerative diseases (NDs) but they possess solitary symptomatic advantages with numerous side effects. Accumulative studies have been conducted to validate the benefit of phytochemicals to treat neurodegenerative diseases including Alzheimer's disease (AD) and Parkinson's disease (PD). In this present review we explored the potential efficacy of phytochemicals such as epigallocatechin-3-galate, berberin, curcumin, resveratrol, quercetin and limonoids against the most common NDs, including Alzheimer's disease (AD) and Parkinson's disease (PD). The beneficial potentials of these phytochemicals have been demonstrated by evidence-based but more extensive investigation needs to be conducted for reducing the progression of AD and PD.
Recommended Citation
Velmurugan, Bharath Kumar; Rathinasamy, Baskaran; Lohanathan, Bharathi Priya; Thiyagarajan, Varadharajan; and Weng, Ching-Feng, "Neuroprotective Role of Phytochemicals." (2018). Department of Pathology, Anatomy, and Cell Biology Faculty Papers. Paper 245.
https://jdc.jefferson.edu/pacbfp/245
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.
PubMed ID
30262792
Language
English
Comments
This article has been peer reviewed. It is the author’s final published version in Molecules, Volume 23, Issue 10, September 2018, Article number 2485.
The published version is available at https://doi.org/10.3390/molecules23102485. Copyright © Velmurugan et al.