Manuscripts from 2024
Metastatic Prostate Adenocarcinoma to the Brain - a Clinicopathologic Analysis of 21 Cases, Namra Ajmal, Yutao Deng, Lawrence C Kenyon, Mark T. Curtis, Mauro Dispagna, Joseph Izes, and Li Li
Keratin 17 Is a Prognostic and Predictive Biomarker in Pancreatic Ductal Adenocarcinoma, Lyanne Delgado-Coka; Lucia Roa-Peña; Sruthi Babu; Michael Horowitz; Emanuel Petricoin; Lynn Matrisian; Edik Blais; Natalia Marchenko; Felicia Allard; Ali Akalin; Wei Jiang, MD, PhD; Brent Larson; Andrew Hendifar; Vincent Picozzi; Minsig Choi; Kenneth Shroyer; and Luisa Escobar-Hoyos
Multi-Organ Gene Expression Analysis and Network Modeling Reveal Regulatory Control Cascades During the Development of Hypertension in Female Spontaneously Hypertensive Rat, Eden Hornung, Sirisha Achanta, Alison Moss, James S. Schwaber, and Rajanikanth Vadigepalli
Neuromodulatory Co-expression in Cardiac Vagal Motor Neurons of the Dorsal Motor Nucleus of the Vagus, Eden Hornung, Shaina Robbins, Ankita Srivastava, Sirisha Achanta, Jin Chen, Zixi Jack Cheng, James Schwaber, and Rajanikanth Vadigepalli
Factitious Disorder Presenting as Sickle Cell Disease: A Case Report, Jeremy Jacobs, Juliana Guarente, Julie Karp, Brenda Grossman, Alyssa Ziman, Andrea McGonigle, Thomas Binns, Tappy Gish, James Gorham, Yara Park, Ingrid Perez-Alvarez, James Burner, Zhen Mei, Dawn Ward, Jennifer Woo, Garrett Booth, Brian Adkins, Christopher Webb, Chisa Yamada, Grace Lee, Elizabeth Abels, Marisa Marques, Elizabeth Allen, Ross Fasano, Elizabeth Crowe, Aaron Tobian, Christopher Tormey, and Evan Bloch
Immunoregulatory Properties of Immune Cells that Associate with the Lens Capsule Surface during Acute and Resolution Phases of Experimental Autoimmune Uveitis, Phuong M. Le, Mary J. Mattapallil, Rachel R. Caspi, Mary Ann Stepp, and A. Sue Menko
Refining the Optimal CAF Cluster Marker for Predicting TME-Dependent Survival Expectancy and Treatment Benefits in NSCLC Patients, Kai Li, Rui Wang, Guo-Wei Liu, Zi-Yang Peng, Ji-Chang Wang, Guo-Dong Xiao, Shou-Ching Tang, Ning Du, Jia Zhang, Jing Zhang, Hong Ren, Xin Sun, Yi-Ping Yang, and Da-Peng Liu
Influences of Quality of Maternal Care and Environmental Enrichment on Associative Memory Function in Rats with Early Life Lead Exposure, Jay S. Schneider, Courtney Williams, Shamaila Zafar, Jaehyun Joo, and Blanca E Himes
Integrated Transcriptomics and Histopathology Approach Identifies a Subset of Rejected Donor Livers With Potential Suitability for Transplantation, Ankita Srivastava, Alexandra Manchel, John Waters, Manju Ambelil, Benjamin K. Barnhart, Jan B. Hoek, Ashesh P. Shah, and Rajanikanth Vadigepalli
Making the Connection: How Membrane Contact Sites Have Changed Our View of Organelle Biology, G. Voeltz, E. Sawyer, G. Hajnóczky, and W. Prinz
Absence of Motor Impairments or Pathological Changes in TMEM230 Knockout Rats, Wenjuan Zhang, Hao Peng, Daihe Yang, Guohua Song, Juan He, Yun Zhou, Cao Huang, and Bo Huang
Manuscripts from 2023
Nonlinear Model Predictive Control of Vagal Nerve Stimulation to Regulate Hemodynamic Variables, Oluwasanmi Adeodu, Michelle Gee, Babak Mahmoudi, Rajanikanth Vadigepalli, and Mayuresh Kothare
Longitudinal Ultrasound Imaging and Network Modeling in Rats Reveal Sex-Dependent Suppression of Liver Regeneration After Resection in Alcoholic Liver Disease, Benjamin K. Barnhart, Toshiki Kan, Ankita Srivastava, Corinne E. Wessner, John Waters, Manju Ambelil, John R. Eisenbrey, Jan B. Hoek, and Rajanikanth Vadigepalli
Autophagy Requirements for Eye Lens Differentiation and Transparency, Lisa Brennan, M Joseph Costello, J Fielding Hejtmancik, A. Menko, S Amer Riazuddin, Alan Shiels, and Marc Kantorow
OPA1 Disease-Causing Mutants Have Domain-Specific Effects on Mitochondrial Ultrastructure and Fusion, Benjamín Cartes-Saavedra, Daniel Lagos, Josefa Macuada, Duxan Arancibia, Florence Burté, Marcela K. Sjöberg-Herrera, María Estela Andrés, Rita Horvath, Patrick Yu-Wai-Man, György Hajnóczky, and Verónica Eisner
Educational Case: Endometrial Ectopia in Endometriosis and Adenomyosis, Carolyn G. Chen and Joanna S.Y. Chan
Sexual Dimorphism in Bidirectional Sr-Mitochondria Crosstalk in Ventricular Cardiomyocytes, Richard T Clements, Radmila Terentyeva, Shanna Hamilton, Paul M L Janssen, Karim Roder, Benjamin Y Martin, Fruzsina Perger, Timothy G Schneider, Zuzana Nichtova, Anindhya S Das, Roland Veress, Beth S Lee, Do-Gyoon Kim, Gideon Koren, Matthew S Stratton, György Csordás, Federica Accornero, Andriy E Belevych, Sandor Gyorke, and Dmitry Terentyev
Immune Responses Induced at One Hour Post Cataract Surgery Wounding of the Chick Lens, JodiRae DeDreu, Morgan Basta, Janice Walker, and Sue Menko
Transcriptomic Changes Predict Metabolic Alterations in LC3 Associated Phagocytosis in Aged Mice, Anuradha Dhingra, John W. Tobias, Nancy J. Philp, and Kathleen Boesze-Battaglia
Educational Case: An Invasive Salivary Gland Tumor: Adenoid Cystic Carcinoma of the Parotid Gland, Jaime Eberle-Singh, Madalina Tuluc, and Joanna Sue Yee Chan
Zinc Treatment Reverses and anti-Zn-Regulated miRs Suppress Esophageal Carcinomas In Vivo, Louise Fong, Kay Huebner, Ruiyan Jing, Karl Smalley, Christopher R Brydges, Oliver Fiehn, John Farber, and Carlo M Croce
Closed-Loop Modeling of Central and Intrinsic Cardiac Nervous System Circuits Underlying Cardiovascular Control, Michelle M. Gee, Abraham M. Lenhoff, James S. Schwaber, Babatunde A. Ogunnaike, and Rajanikanth Vadigepalli
Modeling and Analysis of the Intrinsic Cardiac Nervous System in Closed-Loop Cardiovascular Control, Michelle M. Gee, Abraham M. Lenhoff, James S. Schwaber, Babatunde A. Ogunnaike, and Rajanikanth Vadigepalli
The Involvement of Caspases in the Process of Nuclear Removal During Lens Fiber Cell Differentiation, Rifah Gheyas and A. Sue Menko
Corneal Injury Is Associated With Stromal and Vascular Alterations Within Cranial Dura Mater, Olga V. Glinskii, Vladislav V. Glinsky, Leike Xie, Filiz Bunyak, Vladimir V. Glinskii, Sunilima Sinha, Suneel Gupta, Renato V. Iozzo, and Rajiv R. Mohan
Genetic Sequencing of Breakthrough Severe Acute Respiratory Syndrome Coronavirus 2 Infections in Fully Vaccinated Healthcare Workers, Sara Haddad, John Zurlo, Zi-Xuan Wang, Bonnie Richards, Nitika Badjatia, and Dagan Coppock
Acute ACAT1/SOAT1 Blockade Increases MAM Cholesterol and Strengthens ER-Mitochondria Connectivity., Taylor C Harned, Radu V Stan, Ze Cao, Rajarshi Chakrabarti, Henry N Higgs, Catherine C Y Chang, and Ta Yuan Chang
Undergraduate Medical Student Perspectives on the Role of Autopsy in Medical Education, Patrick Hearle, Wing Fei Wong, and Joanna Chan
Experiential Exposure as the Key to Recruiting Medical Students Into Pathology, Ashley M. Holloman, Mary P. Berg, Bronwyn Bryant, Lisa Ross Dixson, Melissa R. George, Julie Katz Karp, Barbara E.C. Knollmann-Ritschel, Victor Gerardo Prieto, Charles F. Timmons, John Michael Childs, Amanda Lofgreen, Kristen Johnson, and Cindy B. McCloskey
Using Individual Collector Blood Culture Volume Data To Improve Fill Volume, Richard S. Kirby, Jenna M. Meloni, Karishma B. Naik, Matthew D. Minnear, and Matthew A. Pettengill
Enhancement of TKI Sensitivity in Lung Adenocarcinoma through m6A-dependent Translational Repression of Wnt Signaling by circ-FBXW7, Kai Li, Zi-Yang Peng, Rui Wang, Xiang Li, Ning Du, Da-Peng Liu, Jia Zhang, Yun-Feng Zhang, Lei Ma, Ye Sun, Shou-Ching Tang, Hong Ren, Yi-Ping Yang, and Xin Sun
Identification of Dual STRN-NTRK2 Rearrangements in a High Grade Sarcoma, With Good Clinical Response to First-Line Larotrectinib Therapy, Ruihe Lin; Atrayee Basu Mallick; Zi-Xuan Wang, PhD; Scot Andrew Brown; Bo Lu, MD; and Wei Jiang
Increase in hnRNPA1 Expression Suffices to Kill Motor Neurons in Transgenic Rats, Xionghao Liu, Tingting Zhang, Qinxue Wu, Cao Huang, Xu-Gang Xia, Hongxia Zhou, and Bo Huang
Species Delineation and Comparative Genomics within the Campylobacter ureolyticus Complex, Joel J Maki, Mondraya Howard, Sara Connelly, Matthew Pettengill, Dwight J Hardy, and Andrew Cameron
How Influential Are Medical School Curriculum and Other Medical School Characteristics in Students’ Selecting Pathology as a Specialty?, Cindy B. McCloskey, Mark Brissette, John Michael Childs, Amanda Lofgreen, Kristen Johnson, Melissa R. George, Ashley M. Holloman, Bronwyn Bryant, Mary P. Berg, Lisa Ross Dixon, Julie Katz Karp, Barbara E.C. Knollmann-Ritschel, Victor Gerardo Prieto, Charles F. Timmons, and Robert D. Hoffman
Is β-Lactamase Testing Acceptably Accurate for Predicting Haemophilus Influenzae Susceptibility to Β-lactams? Epidemiological Data From Philadelphia, USA, 2017–2023, Arianna B. Morton, Chairut Vareechon, and Matthew A. Pettengill
Primary Adrenal Angiosarcoma: A Case Report and Review of the Literature, Zunaira Naeem, Joon Yau Leong, Arianna Morton, Alaa Hrizat, Eric Shiffrin, Andrew Gomella, Peter McCue, Mark Mann, and Li Li
High expression of Talin-1 is associated with tumor progression and recurrence in melanoma skin cancer patients., Yasaman Rezaie, Fahimeh Fattahi, Baharnaz Mashinchi, Kambiz Kamyab Hesari, Sahar Montazeri, Elham Kalantari, Zahra Madjd, and Leili Saeednejad Zanjani
MICU1 Occludes the Mitochondrial Calcium Uniporter in Divalent-Free Conditions, Macarena Rodríguez-Prados, Elena Berezhnaya, Maria Teresa Castromonte, Sergio L. Menezes-Filho, Melanie Paillard, and György Hajnóczky
Neurotoxicity and Outcomes from Developmental Lead Exposure: Persistent or Permanent?, Jay S. Schneider
The Association Between Higher Expression of Talin-1 and the Reduced Survival Rate in Ovarian Serous Carcinoma Patients, Mina Sharbatoghli, Leili Saeednejad Zanjani, Fahimeh Fattahi, Elham Kalantari, Zohre Habibi Shams, Mahshid Panahi, Medhi Totonchi, Mohsen Asadi-Lari, and Zahra Madjd
IFIT2 Restricts Murine coronavirus Spread to the Spinal Cord White Matter and Its Associated Myelin Pathology, Madhav Sharma, Debanjana Chakravarty, Afaq Hussain, Ajay Zalavadia, Amy Burrows, Patricia Rayman, Nikhil Sharma, Lawrence C. Kenyon, Cornelia Bergmann, Ganes C. Sen, and Jayasri Das Sarma
Estimated Impact of Low Isolate Numbers on the Reliability of Cumulative Antibiogram Data, Christian Tran, John Hargy, Bryan Hess, and Matthew Pettengill
Supporting a Culture of Patient Safety: Resident-Led Patient Safety Event Reviews in a Pathology Residency Training Program, Catherine Tucker; Rebecca C. Jaffe,; and Allison F Goldberg
Educational Case: Ovarian Neoplasms: A Series of Educational Cases to Review Malignancies of Epithelial, Stromal, and Germ Cell Origin, Jordyn B. Tumas and Joanna Chan
Editorial: Targeting DNA Damage Response to Enhance Antitumor Innate Immunity in Radiotherapy, Victoria Valvo, Emanuele Vitale, Marco Tigano, Rachel Evans, Meredith A. Morgan, and Qiang Zhang
Progranulin Oncogenic Network in Solid Tumors, Elisa Ventura, Giacomo Ducci, Reyes Benot Dominguez, Valentina Ruggiero, Antonino Belfiore, Elena Sacco, Marco Vanoni, Renato V. Iozzo, Antonio Giordano, and Andrea Morrione
Global Impact of Proteoglycan Science on Human Diseases, Christopher Xie, Liliana Schaefer, and Renato V. Iozzo
Exploring the Past, Present, and Future of Anti-Angiogenic Therapy in Glioblastoma., Ashley B. Zhang, Khashayar Mozaffari, Brian Aguirre, Victor Li, Rohan Kubba, Nilay C Desai, Darren Wei, Isaac Yang, and Madhuri Wadehra
Manuscripts from 2022
A mathematical model of GLUT1 modulation in rods and RPE and its differential impact in cell metabolism, Andrea Aparicio, Erika T Camacho, Nancy J. Philp, and Stephen A Wirkus
Functional determination of calcium-binding sites required for the activation of inositol 1,4,5-trisphosphate receptors, Vikas Arige, Lara E. Terry, Larry E. Wagner, Sundeep Malik, Mariah R. Baker, Guizhen Fan, Suresh K. Joseph, Irina I Serysheva, and David I. Yule
PI3K Isoform-Specific Regulation of Leader and Follower Cell Function for Collective Migration and Proliferation in Response to Injury, Morgan D Basta, A. Menko, and Janice L Walker
Fluorescence imaging detection of nanodomain redox signaling events at organellar contacts, David M. Booth, Péter Várnai, Suresh K Joseph, and György Hajnóczky
OPA1 Modulates Mitochondrial Ca 2+ Uptake Through ER-Mitochondria Coupling, Benjamín Cartes-Saavedra, Josefa Macuada, Daniel Lagos, Duxan Arancibia, María E Andrés, Patrick Yu-Wai-Man, György Hajnóczky, and Verónica Eisner
Extracellular matrix guidance of autophagy: a mechanism regulating cancer growth, Carolyn Chen and Renato V. Iozzo
Reduced ER-mitochondria connectivity promotes neuroblastoma multidrug resistance., Jorida Çoku, David M. Booth, Jan Skoda, Madison C Pedrotty, Jennifer Vogel, Kangning Liu, Annette Vu, Erica L Carpenter, Jamie C Ye, Michelle A Chen, Peter Dunbar, Elizabeth Scadden, Taekyung D Yun, Eiko Nakamaru-Ogiso, Estela Area-Gomez, Yimei Li, Kelly C Goldsmith, C Patrick Reynolds, György Hajnóczky, and Michael D Hogarty
Interferon Gamma Release Assay Mitogen Responses in COVID-19, Dagan Coppock, Claire E. Zurlo, Jenna M. Meloni, Sara L. Goss, John J. Zurlo, and Matthew A. Pettengill
Glucose Uptake by GLUT1 in Photoreceptors is Essential for Outer Segment Renewal and rod Photoreceptor Survival, Lauren L. Daniele, John Y.S. Han, Ivy S Samuels, Ravikiran Komirisetty, Nikhil Mehta, Jessica L McCord, Minzhong Yu, Yekai Wang, Kathleen Boesze-Battaglia, Brent A Bell, Jianhai Du, Neal S Peachey, and Nancy J. Philp
Uveitis-mediated immune cell invasion through the extracellular matrix of the lens capsule, JodiRae DeDreu, Sonali Pal-Ghosh, Mary J Mattapallil, Rachel R Caspi, Mary Ann Stepp, and A Sue Menko
Uveitis-mediated immune cell invasion through the extracellular matrix of the lens capsule., JodiRae DeDreu, Sonali Pal-Ghosh, Mary J Mattapallil, Rachel R Caspi, Mary Ann Stepp, and A Sue Menko
Bacille Calmette-Guérin vaccine reprograms human neonatal lipid metabolism in vivo and in vitro, Joann Diray-Arce, Asimenia Angelidou, Kristoffer Jarlov Jensen, Maria Giulia Conti, Rachel S Kelly, Matthew Pettengill, Mark Liu, Simon D van Haren, Scott D McCulloch, Greg Michelloti, Olubukola Idoko, Tobias R Kollmann, Beate Kampmann, Hanno Steen, Al Ozonoff, Jessica Lasky-Su, Christine S Benn, and Ofer Levy
Human Dectin-1 Deficiency Impairs Macrophage-Mediated Defense Against Phaeohyphomycosis, Rebecca A. Drummond, Jigar V. Desai, Amy P. Hsu, Vasileios Oikonomou, Donald C. Vinh, Joshua A. Acklin, Michael S. Abers, Magdalena A. Walkiewicz, Sarah L. Anzick, Muthulekha Swamydas, Simon Vautier, Mukil Natarajan, Andrew J. Oler, Daisuke Yamanaka, Katrin D. Mayer-Barber, Yoichiro Iwakura, David Bianchi, Brian Driscoll, Ken Hauck, Ahnika Kline, Nicholas S.P. Viall, Christa S. Zerbe, Elise M.N. Ferré, Monica M. Schmitt, Tom DiMaggio, Stefania Pittaluga, John A. Butman, Adrian M. Zelazny, Yvonne R. Shea, Cesar A. Arias, Cameron Ashbaugh, Maryam Mahmood, Zelalem Temesgen, Alexander G. Theofiles, Masayuki Nigo, Varsha Moudgal, Karen C. Bloch, Sean G. Kelly, M. Suzanne Whitworth, Ganesh Rao, Cindy J. Whitener, Neema Mafi, Juan Gea-Banacloche, Lawrence C. Kenyon, William R. Miller, Katia Boggian, Andrea Gilbert, Matthew Sincock, Alexandra F. Freeman, John E. Bennett, Rodrigo Hasbun, Constantinos M. Mikelis, Kyung J. Kwon-Chung, Yasmine Belkaid, Gordon D. Brown, Jean K. Lim, Douglas B. Kuhns, Steven M. Holland, and Michail S. Lionakis
Suppression of PI3K signaling is linked to autophagy activation and the spatiotemporal induction of the lens organelle free zone, Rifah Gheyas, Ramon Ortega-Alvarez, Daniel Chauss, Marc Kantorow, and A. Menko
Unreliable Automated Complete Blood Count Results: Causes, Recognition, and Resolution, Gene Gulati, Guldeep Uppal, and Jerald Z. Gong
Microbial Cell Factory of Baccatin III Preparation in Escherichia coli by Increasing DBAT Thermostability and in vivo Acetyl-CoA Supply, Jia-Jun Huang, Tao Wei, Zhi-Wei Ye, Qian-Wang Zheng, Bing-Hua Jiang, Wen-Feng Han, An-Qi Ye, Pei-Yun Han, Li-Qiong Guo, and Jun-Fang Lin
Capture at the ER-Mitochondrial Contacts Licenses IP, Máté Katona, Ádám Bartók, Zuzana Nichtova, György Csordás, Elena Berezhnaya, David Weaver, Arijita Ghosh, Péter Várnai, David I. Yule, and György Hajnóczky
68-year old man with progressive weakness and ventilator dependent respiratory failure: a case report of sporadic late onset nemaline myopathy, P. Kirupaharan, Daniel Kramer, Alan Gandler, Lawrence C. Kenyon, and Ross Summer
BAP1 Maintains Hif-Dependent Interferon Beta Induction to Suppress Tumor Growth in Clear Cell Renal Cell Carcinoma., Lauren Langbein, Rayan El Hajjar, Shen He, Eleonora Sementino, Zhijiu Zhong, Wei Jiang, Benjamin E Leiby, Li Li, Robert G Uzzo, Joseph R Testa, and Haifeng Yang
Data Supporting the Roles of BAP1, Sting, and IFN-β in ISGF3 Activation in ccRCC, Lauren E Langbein, Eleonora Sementino, Zhijiu Zhong, Wei Jiang, Li Li, Joseph R Testa, and Haifeng Yang
Patient with Multiple Genetically Distinct Thyroid Nodules Including Papillary Thyroid Carcinoma Harboring Novel YWHAG-BRAF Fusion, Ruihe Lin, Zi-Xuan Wang, Elizabeth Cottrill, Nitika Badjatia, and Stacey Gargano
miR-196a Upregulation Contributes to Gefitinib Resistance through Inhibiting GLTP Expression, Bing-Jie Liu, Fang-Fang Li, Yun-Xia Xie, Chong-Yuan Fan, Wen-Jing Liu, Jian-Ge Qiu, and Bing-Hua Jiang
Reactive oxygen species reprogram macrophages to suppress antitumor immune response through the exosomal miR-155-5p/PD-L1 pathway, Xiang Li, Shaomin Wang, Wei Mu, Jennifer Barry, Anna Han, Richard L Carpenter, Bing-Hua Jiang, Stephen C Peiper, M G Mahoney, A E Aplin, Hong Ren, and Jun He
Patient-Specific Genome-Scale Metabolic Models for Individualized Predictions of Liver Disease, Alexandra Manchel, Jan B. Hoek, Ramon Bataller, Radhakrishnan Mahadevan, and Rajanikanth Vadigepalli
Genome-Scale Metabolic Modeling Reveals Sequential Dysregulation of Glutathione Metabolism in Livers from Patients with Alcoholic Hepatitis, Alexandra Manchel, Radhakrishnan Mahadevan, Ramon Bataller, Jan B. Hoek, and Rajanikanth Vadigepalli
Patterns of Crystallin Gene Expression in Differentiation State Specific Regions of the Embryonic Chicken Lens, Zhiwei Ma, Daniel Chauss, Joshua Disatham, Xiaodong Jiao, Lisa Ann Brennan, A Sue Menko, Marc Kantorow, and J Fielding Hejtmancik
The Pro-fibrotic Response of Mesenchymal Leader Cells to Lens Wounding Involves Hyaluronic Acid, Its Receptor RHAMM, and Vimentin, A. Sue Menko, Alison Romisher, and Janice L Walker
The Pro-Fibrotic Response to Lens Injury is Signaled in a PI3K Isoform-Specific Manner, A. Sue Menko and Janice L. Walker
The Role of Decorin Proteoglycan in Mitophagy., Thomas Neill and Renato V. Iozzo
Single-cell systems neuroscience: A growing frontier in mental illness, Sean O'Sullivan
Germline Polymorphisms in MGMT Associated With Temozolomide-Related Myelotoxicity Risk in Patients With Glioblastoma Treated on NRG Oncology/RTOG 0825, Michael E Scheurer, Renke Zhou, Mark R Gilbert, Melissa L Bondy, Erik P Sulman, Ying Yuan, Yanhong Liu, Elizabeth Vera, Merideth M Wendland, Emad F Youssef, Volker W Stieber, Ritsuko R Komaki, John C Flickinger, Lawrence C. Kenyon, H Ian Robins, Grant K Hunter, Ian R Crocker, Samuel T Chao, Stephanie L Pugh, and Terri S Armstrong
Altered Expression of Glycobiology-Related Genes in Parkinson’s Disease Brain, Jay S Schneider and Garima Singh
GM1 ganglioside modifies microglial and neuroinflammatory responses to α-synuclein in the rat AAV-A53T α-synuclein model of Parkinson's disease, Jay S Schneider, Garima Singh, Courtney K. Williams, and Vikrant Singh
Altered Genome-wide Hippocampal Gene Expression Profiles Following Early Life Lead Exposure and Their Potential for Reversal by Environmental Enrichment, Garima Singh, V Singh, T Kim, A Ertel, W Fu, and J S Schneider
Uncontrolled mitochondrial calcium uptake underlies the pathogenesis of neurodegeneration in MICU1-deficient mice and patients, Raghavendra Singh, Adam Bartok, Melanie Paillard, Ashley L. Tyburski, Melanie B Elliott, and György Hajnóczky
Complexity of Progranulin Mechanisms of Action in Mesothelioma, Elisa Ventura, Christopher Xie, Simone Buraschi, Antonino Belfiore, Renato V. Iozzo, Antonio Giordano, and Andrea Morrione
Oncosuppressive roles of decorin through regulation of multiple receptors and diverse signaling pathways., Christopher Xie, Dipon K Mondal, Mikdat Ulas, Thomas Neill, and Renato V Iozzo
Human endothelial cells promote arsenic-transformed lung epithelial cells to induce tumor growth and angiogenesis through interleukin-8 induction, Lei Zhao, Yi-Fang Wang, Jie Liu, Bing-Hua Jiang, and Ling-Zhi Liu
Manuscripts from 2021
Dabigatran reduces thrombin-induced neuroinflammation and AD markers in vitro: Therapeutic relevance for Alzheimer's disease, Syed Waseem Bihaqi, Haripriya Vittal Rao, Abhik Sen, and Paula Grammas
The Role of Decorin and Biglycan Signaling in Tumorigenesis, Valentina Diehl, Lisa Sophie Huber, Jonel Trebicka, Malgorzata Wygrecka, Renato V. Iozzo, and Liliana Schaefer
Simultaneous brain and intramedullary spinal abscesses in a patient with Streptococcus intermedius infection, David P. Friedman, Joseph DeSimone Jr, Aaron Christensen, and Matthew Pettengill
Characterization and Clinical Significance of EIF1AX Mutations and Co-Mutations in Cytologically Indeterminate Thyroid Nodules: A 5-Year Retrospective Analysis., Stacey Gargano; Nitika Badjatia; Yanina Nikolaus; Stephen C Peiper; and Zi-Xuan Wang, PhD
Genetic Variants and Tumor Immune Microenvironment: Clues for Targeted Therapies in Inflammatory Breast Cancer (IBC), Yulan Gong, Rajeswari Nagarathinam, Maria F. Arisi, Lorenzo Gerratana, Jennifer S Winn, Michael Slifker, Jianming Pei, Kathy Q Cai, Zachary Hasse, Elias Obeid, Julio Noriega, Christopher Sebastiano, Eric Ross, Katherine Alpaugh, Massimo Cristofanilli, and Sandra V Fernandez
Clinical Performance of the Point-of-Care cobas Liat for Detection of SARS-CoV-2 in 20 Minutes: a Multicenter Study., Glen Hansen, Jamie Marino, Zi-Xuan Wang, Kathleen G Beavis, John Rodrigo, Kylie Labog, Lars F Westblade, Run Jin, Nedra Love, Karen Ding, Sachin Garg, Alan Huang, Joanna Sickler, and Nam K Tran
3D single cell scale anatomical map of sex-dependent variability of the rat intrinsic cardiac nervous system., Clara Leung, Shaina Robbins, Alison Moss, Maci Heal, Mahyar Osanlouy, Richard Christie, Navid Farahani, Corey Monteith, Jin Chen, Peter Hunter, Susan Tappan, Rajanikanth Vadigepalli, Zixi Jack Cheng, and James S. Schwaber
The Immunotherapy Candidate TNFSF4 May Help the Induction of a Promising Immunological Response in Breast Carcinomas, Kai Li, Lei Ma, Ye Sun, Xiang Li, Hong Ren, Shou-Ching Tang, and Xin Sun
M6A associated TSUC7 inhibition contributed to Erlotinib resistance in lung adenocarcinoma through a notch signaling activation dependent way, Kai Li, Zi-Yang Peng, Shan Gao, Qing-Shi Wang, Rui Wang, Xiang Li, Guo-Dong Xiao, Jing Zhang, Hong Ren, Shou-Ching Tang, and Xin Sun
NOX4 Signaling Mediates Cancer Development and Therapeutic Resistance through HER3 in Ovarian Cancer Cells., Wen-Jing Liu, Ying-Xue Huang, Wei Wang, Ye Zhang, Bing-Jie Liu, Jian-Ge Qiu, Bing-Hua Jiang, and Ling-Zhi Liu
Resident immune cells of the avascular lens: Mediators of the injury and fibrotic response of the lens., A. Menko, JodiRae DeDreu, Caitlin M. Logan, Heather Paulson, Alex V Levin, and Janice L Walker
A single cell transcriptomics map of paracrine networks in the intrinsic cardiac nervous system., Alison Moss, Shaina Robbins, Sirisha Achanta, Lakshmi Kuttippurathu, Scott Turick, Sean Nieves, Peter Hanna, Elizabeth H. Smith, Donald B. Hoover, Jin Chen, Zixi Jack Cheng, Jeffrey L. Ardell, Kalyanam Shivkumar, James S. Schwaber, and Rajanikanth Vadigepalli
