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Manuscripts from 2025

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Short Term Hemodynamic Effects of Atrial Fibrillation in a Closed-Loop Human Cardiac-Baroreflex System, Oluwasanmi Adeodu, Michelle Gee, Babak Mahmoudi, Rajanikanth Vadigepalli, and Mayuresh V. Kothare

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Barriers to Achieving Graduated Responsibility: Preparing Pathology Residents for Independent Practice, Bronwyn H. Bryant, Balaram Puligandla, Hailey L. Gosnell, Kristen Johnson, Stephanie Barak, Mary P. Berg, Satyapal Chahar, John M. Childs, Julie Katz Karp, Amanda Lofgreen, Cindy B. McCloskey, Barbara E. C. Knollmann-Ritschel, Kristie L. White, and W. Stephen Black-Schaffer

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Dependence of Mitochondrial Calcium Signalling and Dynamics on the Disaggregase, CLPB, Donato D'Angelo, Víctor H. Sánchez-Vázquez, Benjamín Cartes-Saavedra, Denis Vecellio Reane, Ryan R. Cupo, Hilda Delgado de la Herran, Giorgia Ghirardo, James Shorter, Ron A. Wevers, Saskia B. Wortmann, Fabiana Perocchi, Rosario Rizzuto, Anna Raffaello, and György Hajnóczky

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Lower Cytoplasmic Expression of DDIT4 Is Associated With Poor Prognosis in Gastric Cancer Patients, Masoumeh Dehghan Manshadi, Fatemeh Tajik, Leili Saeednejad Zanjani, Farideh Hashemi, Mandana Rahimi, Fahimeh Fattahi, Sadegh Safaei, Zahra Madjd, and Roya Ghods

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Uncovering the PML::RARA Fusion in Cytogenetically Cryptic and FISH-Negative Acute Promyelocytic Leukemia-A Case Report and Comprehensive Literature Review, Busra Delikkaya, Jaime Eberle-Singh, Arianna Morton, Jerald Gong, and Jinglan Liu

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Amino Acid Transporter LAT1 (slc7a5) Promotes Metabolic Rewiring in Tnbc Progression Through the L-Trp/Qprt/Nad+ Pathway, Margot Y. Fedoroff, Lei Zhao, Shaomin Wang, Alok Bhushan, Haifeng Yang, Karen M. Bussard, Stephen C. Peiper, and Jun He

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Educational Case: Diabetic Nephropathy, Emily W. Gripp and Joanna Chan

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Pivotal Roles of Biglycan and Decorin in Regulating Bone Mass, Water Retention, and Bone Toughness, Rui Hua, Yan Han, Qingwen Ni, Roberto J. Fajardo, Renato V. Iozzo, Rafay Ahmed, Jeffry S. Nyman, Xiaodu Wang, and Jean X. Jiang

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Stability of microRNAs in Serum and Plasma Reveal Promise as a Circulating Biomarker, Erryk S. Katayama, Jonathan J. Hue, Alexander W. Loftus, Semmer A. Ali, Hallie J. Graor, Luke D. Rothermel, Eric R. Londin, Mehrdad Zarei, and Jordan M. Winter

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Perceived Gaps in Preparation for Pathology Residency and Opportunities for Improvement, Barbara Knollmann-Ritschel, Julie Karp, Stephanie Barak, John Childs, Kristen Johnson, Amanda Lofgreen, Mary Berg, Satyapal Chahar, Hailey Gosnell, Cindy McCloskey, Balaram Puligandla, Kristie White, and Bronwyn Bryant

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Co-option of Mitochondrial Nucleic Acid-Sensing Pathways by HSV-1 UL12.5 for Reactivation From Latent Infection, Patryk A. Krakowiak, Matthew E. Flores, Sean R. Cuddy, Abigail L. Whitford, Sara A. Dochnal, Aleksandra Babnis, Tsuyoshi Miyake, Marco Tigano, Daniel A. Engel, and Anna R. Cliffe

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Distinct Transcriptional Regulation of the Wnt and TGFβ Signaling Families Associated With Wound Healing and Fibrotic Outcomes to Lens Injury, Catherine Lalman, Kylie R. Stabler, Joshua Disatham, Lisa A. Brennan, Marc Kantorow, and Janice L. Walker

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Supervised Machine-Based Learning and Computational Analysis to Reveal Unique Molecular Signatures Associated with Wound Healing and Fibrotic Outcomes to Lens Injury, Catherine Lalman, Kylie R. Stabler, Yimin Yang, and Janice L Walker

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Artificial Intelligence in Ocular Transcriptomics: Applications of Unsupervised and Supervised Learning, Catherine Lalman, Yimin Yang, and Janice L. Walker

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Matrix Molecules Associated With Both Regulation of Inflammation and Pathogenic Outcomes Associated With the Surface of the Lens in the Eyes of Eau Mice, Phuong M. Le, JodiRae DeDreu, Mary J Mattapallil, Rachel R Caspi, Ryan Tomlinson, Mary Ann Stepp, and A. Sue Menko

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Functional Effects of Heavy Metal Exposures on N6-Methyladenosine (m6A) Methylation and Other Epitranscriptomic Modifications in the Central Nervous System, Niraj Lodhi, Lauren Powell, and Jay S. Schneider

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Dynamics and Malleability of Plant DNA Methylation During Abiotic Stresses, Niraj Lodhi and Rakesh Srivastava

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Case Report: Myeloid Neoplasms With the t(3;12)(q26.2;p13.1)/ MECOM-ETV6 Translocation: Report of Two New Cases and Review of the Literature, Soumya Mikkilineni; Juan Pablo Pineda-Reyes; Lindsay Wilde; Andres Ferber; Zi-Xuan Wang; Stephen Peiper; Guldeep Uppal, MD; Jerald Gong; and Jinglan Liu

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Culture Harder: Use More Specimen to Increase Methicillin-Resistant Staphylococcus Aureus Culture Yield Relative to PCR, Arvette E. Mitchell, Arpit P. Patel, Jennifer DiCandilo, Zachary W. Rebollido, and Matthew Pettengill

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Erratum: Culture Harder: Use More Specimen to Increase Methicillin-Resistant Staphylococcus Aureus Culture Yield Relative to PCR, Arvette E. Mitchell, Arpit P. Patel, Jennifer DiCandilo, Zachary W. Rebollido, and Matthew Pettengill

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Mitochondrial Membrane Hyperpolarization Modulates Nuclear DNA Methylation and Gene Expression Through Phospholipid Remodeling, Mateus Mori, Oswaldo Lozoya, Ashley Brooks, Carl Bortner, Cristina Nadalutti, Birgitta Ryback, Brittany Rickard, Marta Overchuk, Imran Rizvi, Tatiana Rogasevskaia, Kai Huang, Prottoy Hasan, György Hajnóczky, and Janine Santos

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Dynamic Rewiring of MicroRNA Networks in the Brainstem Autonomic Control Circuits During Hypertension Development in the Female Spontaneously Hypertensive Rat, Alison Moss, Ankita Srivastava, Lakshmi Kuttippurathu, James S. Schwaber, and Rajanikanth Vadigepalli

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VDAC2 and Bak Scarcity in Liver Mitochondria Enables Targeting Hepatocarcinoma While Sparing Hepatocytes, Shamim Naghdi, Piyush Mishra, Soumya S. Roy, David Weaver, Ludivine Walter, Erika Davies, Anil N. Antony, Xuena Lin, Gisela Moehren, Mark A. Feitelson, Christopher A. Reed, Tullia Lindsten, Craig B. Thompson, Hien T. Dang, Jan B. Hoek, Erik S. Knudsen, and György Hajnóczky

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Clinical Significance of "S" Isoform of DCLK1 in Different Gastric Cancer Subtypes Using Newly Produced Monoclonal Antibody, Mahdieh Razmi, Ali-Ahmad Bayat, Nafiseh Mortazavi, Elham Kalantari, Leili Saeednejad Zanjani, Sima Saki, Roya Ghods, and Zahra Madjd

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Neovascular Pruning by IDO1 Inhibitors Can Potentiate Immunogenic Cytotoxicity of Ischemia-Targeted Agents to Synergistically Enhance Anti-PD-1 Responsiveness, Shih-Chun Shen, Souvik Dey, James B. DuHadaway, Erika Sutanto-Ward, Maurice T. Hampton, Serguei V. Kozlov, George C. Prendergast, and Alexander J. Muller

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Editorial: Wearable Technology: The New Ornament of Network Physiology, Ankita Srivastava and Santosh Kumar Yadav

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RUNX2 Cooperates With SREBP1 to Rewire Cancer Metabolism and Promote Aggressiveness, Emanuele Vitale, Mila Gugnoni, Veronica Manicardi, Silvia Muccioli, Federica Torricelli, Benedetta Donati, Simonetta Piana, Gloria Manzotti, Elisa Salviato, Francesca Reggiani, Cristian Ascione, Rebecca Vezzani, Moira Ragazzi, Mattia Forcato, Oriana Romano, Silvio Bicciato, Aaron Goldman, Marco Tigano, and Alessia Ciarrocchi

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Astrocytes Expressing Mutant hnRNPA1 Induce Non-Cell-Autonomous Motor Neuron Death, Qinxue Wu, Xionghao Liu, Tingting Zhang, Shiquan Cui, Bo Huang, Cao Huang, Qilin Cao, Xu-Gang Xia, and Hongxia Zhou

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The Heterogeneity of 13q Deletions in Chronic Lymphocytic Leukemia: Diagnostic Challenges and Clinical Implications, Changqing Xia, Guang Liu, Jinglan Liu, Arash Ronaghy, Saber Tadros, Wei Wang, Hong Fang, Shanxiang Zhang, Joseph D. Khoury, and Zhenya Tang

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Rescue of the First Mitochondrial Membrane Carrier, the mPiC, by TAT-Mediated Protein Replacement Treatment, Samar Zabit, Orly Melloul, Michal Lichtenstein, Erin L. Seifert, and Haya Lorberboum-Galski

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Developmental Lead Exposure and Aggression in Male Rats: Influences of Maternal Care and Environmental Enrichment, Shamaila Zafar, Courtney K. Williams, Jaehyun Joo, Blanca E. Himes, and Jay S. Schneider

Manuscripts from 2024

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Metastatic Prostate Adenocarcinoma to the Brain - a Clinicopathologic Analysis of 21 Cases, Namra Ajmal, Yutao Deng, Lawrence C Kenyon, Mark T. Curtis, Mauro Dispagna, Joseph Izes, and Li Li

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Mammalian Mitochondrial Inorganic Polyphosphate (polyP) and Cell Signaling: Crosstalk Between PolyP and the Activity of AMPK, Renata T. Da Costa, Anna Nichenko, Matheus M. Perez, Malgorzata Tokarska-Schlattner, Sheida Kavehmoghaddam, Vedangi Hambardikar, Ernest R. Scoma, Erin L. Seifert, Uwe Schlattner, Joshua C. Drake, and Maria E. Solesio

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Keratin 17 Is a Prognostic and Predictive Biomarker in Pancreatic Ductal Adenocarcinoma, Lyanne Delgado-Coka; Lucia Roa-Peña; Sruthi Babu; Michael Horowitz; Emanuel Petricoin; Lynn Matrisian; Edik Blais; Natalia Marchenko; Felicia Allard; Ali Akalin; Wei Jiang, MD, PhD; Brent Larson; Andrew Hendifar; Vincent Picozzi; Minsig Choi; Kenneth Shroyer; and Luisa Escobar-Hoyos

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Multi-Organ Gene Expression Analysis and Network Modeling Reveal Regulatory Control Cascades During the Development of Hypertension in Female Spontaneously Hypertensive Rat, Eden Hornung, Sirisha Achanta, Alison Moss, James S. Schwaber, and Rajanikanth Vadigepalli

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Neuromodulatory Co-expression in Cardiac Vagal Motor Neurons of the Dorsal Motor Nucleus of the Vagus, Eden Hornung, Shaina Robbins, Ankita Srivastava, Sirisha Achanta, Jin Chen, Zixi Jack Cheng, James Schwaber, and Rajanikanth Vadigepalli

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Institutional Experience of Lymphoproliferative Disorders with Initial Diagnosis Made via Fine Needle Aspiration at Otolaryngology Clinic, Alaa S. Hrizat, Jerald Gong, and Stacey M. Gargano

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Factitious Disorder Presenting as Sickle Cell Disease: A Case Report, Jeremy Jacobs, Juliana Guarente, Julie Karp, Brenda Grossman, Alyssa Ziman, Andrea McGonigle, Thomas Binns, Tappy Gish, James Gorham, Yara Park, Ingrid Perez-Alvarez, James Burner, Zhen Mei, Dawn Ward, Jennifer Woo, Garrett Booth, Brian Adkins, Christopher Webb, Chisa Yamada, Grace Lee, Elizabeth Abels, Marisa Marques, Elizabeth Allen, Ross Fasano, Elizabeth Crowe, Aaron Tobian, Christopher Tormey, and Evan Bloch

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Immunoregulatory Properties of Immune Cells that Associate with the Lens Capsule Surface during Acute and Resolution Phases of Experimental Autoimmune Uveitis, Phuong M. Le, Mary J. Mattapallil, Rachel R. Caspi, Mary Ann Stepp, and A. Sue Menko

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Refining the Optimal CAF Cluster Marker for Predicting TME-Dependent Survival Expectancy and Treatment Benefits in NSCLC Patients, Kai Li, Rui Wang, Guo-Wei Liu, Zi-Yang Peng, Ji-Chang Wang, Guo-Dong Xiao, Shou-Ching Tang, Ning Du, Jia Zhang, Jing Zhang, Hong Ren, Xin Sun, Yi-Ping Yang, and Da-Peng Liu

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OPA1 And Disease-Causing Mutants Perturb Mitochondrial Nucleoid Distribution, J. Macuada, I. Molina-Riquelme, G. Vidal, N. Pérez-Bravo, C. Vásquez-Trincado, G. Aedo, D. Lagos, P. Yu-Wai-Man, R. Horvath, T. J. Rudge, B. Cartes-Saavedra, and V. Eisner

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From Sampling to Simulating: Single-Cell Multiomics in Systems Pathophysiological Modeling, Alexandra Manchel, Michelle M. Gee, and Rajanikanth Vadigepalli

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Proteoglycans of Basement Membranes: Crucial Controllers of Angiogenesis, Neurogenesis, and Autophagy, Maurizio Mongiat, Gabriel Pascal, Evelina Poletto, Davion M. Williams, and Renato V. Iozzo

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Nuclear Expression of Dynamin 2 Is Associated With Tumor Aggressiveness in Bladder Cancer Patients: A Bioinformatics and Experimental Approach, Mahdieh Razmi, Leili Saeednejad Zanjani, Mandana Rahimi, Roya Sajed, Sadegh Safaei, Zahra Madjd, and Roya Ghods

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Influences of Quality of Maternal Care and Environmental Enrichment on Associative Memory Function in Rats with Early Life Lead Exposure, Jay S. Schneider, Courtney Williams, Shamaila Zafar, Jaehyun Joo, and Blanca E. Himes

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Integrated Transcriptomics and Histopathology Approach Identifies a Subset of Rejected Donor Livers With Potential Suitability for Transplantation, Ankita Srivastava, Alexandra Manchel, John Waters, Manju Ambelil, Benjamin K. Barnhart, Jan B. Hoek, Ashesh P. Shah, and Rajanikanth Vadigepalli

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Clearing the Light Path: Proteoglycans and Their Important Roles in the Lens and Cornea, Mary Ann Stepp and A. Sue Menko

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Making the Connection: How Membrane Contact Sites Have Changed Our View of Organelle Biology, G. Voeltz, E. Sawyer, G. Hajnóczky, and W. Prinz

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Transcriptional Regulation in the Absence of Inositol Trisphosphate Receptor Calcium Signaling, Michael Young, David M. Booth, David Smith, Marco Tigano, György Hajnóczky, and Suresh K. Joseph

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Absence of Motor Impairments or Pathological Changes in TMEM230 Knockout Rats, Wenjuan Zhang, Hao Peng, Daihe Yang, Guohua Song, Juan He, Yun Zhou, Cao Huang, and Bo Huang

Manuscripts from 2023

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Nonlinear Model Predictive Control of Vagal Nerve Stimulation to Regulate Hemodynamic Variables, Oluwasanmi Adeodu, Michelle Gee, Babak Mahmoudi, Rajanikanth Vadigepalli, and Mayuresh Kothare

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Longitudinal Ultrasound Imaging and Network Modeling in Rats Reveal Sex-Dependent Suppression of Liver Regeneration After Resection in Alcoholic Liver Disease, Benjamin K. Barnhart, Toshiki Kan, Ankita Srivastava, Corinne E. Wessner, John Waters, Manju Ambelil, John R. Eisenbrey, Jan B. Hoek, and Rajanikanth Vadigepalli

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Autophagy Requirements for Eye Lens Differentiation and Transparency, Lisa Brennan, M Joseph Costello, J Fielding Hejtmancik, A. Menko, S Amer Riazuddin, Alan Shiels, and Marc Kantorow

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OPA1 Disease-Causing Mutants Have Domain-Specific Effects on Mitochondrial Ultrastructure and Fusion, Benjamín Cartes-Saavedra, Daniel Lagos, Josefa Macuada, Duxan Arancibia, Florence Burté, Marcela K. Sjöberg-Herrera, María Estela Andrés, Rita Horvath, Patrick Yu-Wai-Man, György Hajnóczky, and Verónica Eisner

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Educational Case: Endometrial Ectopia in Endometriosis and Adenomyosis, Carolyn G. Chen and Joanna S.Y. Chan

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Sexual Dimorphism in Bidirectional Sr-Mitochondria Crosstalk in Ventricular Cardiomyocytes, Richard T Clements, Radmila Terentyeva, Shanna Hamilton, Paul M L Janssen, Karim Roder, Benjamin Y Martin, Fruzsina Perger, Timothy G Schneider, Zuzana Nichtova, Anindhya S Das, Roland Veress, Beth S Lee, Do-Gyoon Kim, Gideon Koren, Matthew S Stratton, György Csordás, Federica Accornero, Andriy E Belevych, Sandor Gyorke, and Dmitry Terentyev

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Immune Responses Induced at One Hour Post Cataract Surgery Wounding of the Chick Lens, JodiRae DeDreu, Morgan Basta, Janice Walker, and Sue Menko

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Transcriptomic Changes Predict Metabolic Alterations in LC3 Associated Phagocytosis in Aged Mice, Anuradha Dhingra, John W. Tobias, Nancy J. Philp, and Kathleen Boesze-Battaglia

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Educational Case: An Invasive Salivary Gland Tumor: Adenoid Cystic Carcinoma of the Parotid Gland, Jaime Eberle-Singh, Madalina Tuluc, and Joanna Sue Yee Chan

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Zinc Treatment Reverses and anti-Zn-Regulated miRs Suppress Esophageal Carcinomas In Vivo, Louise Fong, Kay Huebner, Ruiyan Jing, Karl Smalley, Christopher R Brydges, Oliver Fiehn, John Farber, and Carlo M Croce

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Closed-Loop Modeling of Central and Intrinsic Cardiac Nervous System Circuits Underlying Cardiovascular Control, Michelle M. Gee, Abraham M. Lenhoff, James S. Schwaber, Babatunde A. Ogunnaike, and Rajanikanth Vadigepalli

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Modeling and Analysis of the Intrinsic Cardiac Nervous System in Closed-Loop Cardiovascular Control, Michelle M. Gee, Abraham M. Lenhoff, James S. Schwaber, Babatunde A. Ogunnaike, and Rajanikanth Vadigepalli

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The Involvement of Caspases in the Process of Nuclear Removal During Lens Fiber Cell Differentiation, Rifah Gheyas and A. Sue Menko

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Corneal Injury Is Associated With Stromal and Vascular Alterations Within Cranial Dura Mater, Olga V. Glinskii, Vladislav V. Glinsky, Leike Xie, Filiz Bunyak, Vladimir V. Glinskii, Sunilima Sinha, Suneel Gupta, Renato V. Iozzo, and Rajiv R. Mohan

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Genetic Sequencing of Breakthrough Severe Acute Respiratory Syndrome Coronavirus 2 Infections in Fully Vaccinated Healthcare Workers, Sara Haddad, John Zurlo, Zi-Xuan Wang, Bonnie Richards, Nitika Badjatia, and Dagan Coppock

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Acute ACAT1/SOAT1 Blockade Increases MAM Cholesterol and Strengthens ER-Mitochondria Connectivity., Taylor C Harned, Radu V Stan, Ze Cao, Rajarshi Chakrabarti, Henry N Higgs, Catherine C Y Chang, and Ta Yuan Chang

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Undergraduate Medical Student Perspectives on the Role of Autopsy in Medical Education, Patrick Hearle, Wing Fei Wong, and Joanna Chan

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Experiential Exposure as the Key to Recruiting Medical Students Into Pathology, Ashley M. Holloman, Mary P. Berg, Bronwyn Bryant, Lisa Ross Dixson, Melissa R. George, Julie Katz Karp, Barbara E.C. Knollmann-Ritschel, Victor Gerardo Prieto, Charles F. Timmons, John Michael Childs, Amanda Lofgreen, Kristen Johnson, and Cindy B. McCloskey

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Using Individual Collector Blood Culture Volume Data To Improve Fill Volume, Richard S. Kirby, Jenna M. Meloni, Karishma B. Naik, Matthew D. Minnear, and Matthew A. Pettengill

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Enhancement of TKI Sensitivity in Lung Adenocarcinoma through m6A-dependent Translational Repression of Wnt Signaling by circ-FBXW7, Kai Li, Zi-Yang Peng, Rui Wang, Xiang Li, Ning Du, Da-Peng Liu, Jia Zhang, Yun-Feng Zhang, Lei Ma, Ye Sun, Shou-Ching Tang, Hong Ren, Yi-Ping Yang, and Xin Sun

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Identification of Dual STRN-NTRK2 Rearrangements in a High Grade Sarcoma, With Good Clinical Response to First-Line Larotrectinib Therapy, Ruihe Lin; Atrayee Basu Mallick; Zi-Xuan Wang, PhD; Scot Andrew Brown; Bo Lu, MD; and Wei Jiang

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Increase in hnRNPA1 Expression Suffices to Kill Motor Neurons in Transgenic Rats, Xionghao Liu, Tingting Zhang, Qinxue Wu, Cao Huang, Xu-Gang Xia, Hongxia Zhou, and Bo Huang

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Species Delineation and Comparative Genomics within the Campylobacter ureolyticus Complex, Joel J Maki, Mondraya Howard, Sara Connelly, Matthew Pettengill, Dwight J Hardy, and Andrew Cameron

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How Influential Are Medical School Curriculum and Other Medical School Characteristics in Students’ Selecting Pathology as a Specialty?, Cindy B. McCloskey, Mark Brissette, John Michael Childs, Amanda Lofgreen, Kristen Johnson, Melissa R. George, Ashley M. Holloman, Bronwyn Bryant, Mary P. Berg, Lisa Ross Dixon, Julie Katz Karp, Barbara E.C. Knollmann-Ritschel, Victor Gerardo Prieto, Charles F. Timmons, and Robert D. Hoffman

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Is β-Lactamase Testing Acceptably Accurate for Predicting Haemophilus Influenzae Susceptibility to Β-lactams? Epidemiological Data From Philadelphia, USA, 2017–2023, Arianna B. Morton, Chairut Vareechon, and Matthew A. Pettengill

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Primary Adrenal Angiosarcoma: A Case Report and Review of the Literature, Zunaira Naeem, Joon Yau Leong, Arianna Morton, Alaa Hrizat, Eric Shiffrin, Andrew Gomella, Peter McCue, Mark Mann, and Li Li

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High expression of Talin-1 is associated with tumor progression and recurrence in melanoma skin cancer patients., Yasaman Rezaie, Fahimeh Fattahi, Baharnaz Mashinchi, Kambiz Kamyab Hesari, Sahar Montazeri, Elham Kalantari, Zahra Madjd, and Leili Saeednejad Zanjani

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MICU1 Occludes the Mitochondrial Calcium Uniporter in Divalent-Free Conditions, Macarena Rodríguez-Prados, Elena Berezhnaya, Maria Teresa Castromonte, Sergio L. Menezes-Filho, Melanie Paillard, and György Hajnóczky

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GM1 Ganglioside as a Disease-Modifying Therapeutic for Parkinson’s Disease: A Multi-Functional Glycosphingolipid That Targets Multiple Parkinson’s Disease-Relevant Pathogenic Mechanisms, Jay S. Schneider

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Neurotoxicity and Outcomes from Developmental Lead Exposure: Persistent or Permanent?, Jay S. Schneider

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The Association Between Higher Expression of Talin-1 and the Reduced Survival Rate in Ovarian Serous Carcinoma Patients, Mina Sharbatoghli, Leili Saeednejad Zanjani, Fahimeh Fattahi, Elham Kalantari, Zohre Habibi Shams, Mahshid Panahi, Medhi Totonchi, Mohsen Asadi-Lari, and Zahra Madjd

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IFIT2 Restricts Murine coronavirus Spread to the Spinal Cord White Matter and Its Associated Myelin Pathology, Madhav Sharma, Debanjana Chakravarty, Afaq Hussain, Ajay Zalavadia, Amy Burrows, Patricia Rayman, Nikhil Sharma, Lawrence C. Kenyon, Cornelia Bergmann, Ganes C. Sen, and Jayasri Das Sarma

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Estimated Impact of Low Isolate Numbers on the Reliability of Cumulative Antibiogram Data, Christian Tran, John Hargy, Bryan Hess, and Matthew Pettengill

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Supporting a Culture of Patient Safety: Resident-Led Patient Safety Event Reviews in a Pathology Residency Training Program, Catherine Tucker; Rebecca C. Jaffe,; and Allison F Goldberg

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Educational Case: Ovarian Neoplasms: A Series of Educational Cases to Review Malignancies of Epithelial, Stromal, and Germ Cell Origin, Jordyn B. Tumas and Joanna Chan

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Editorial: Targeting DNA Damage Response to Enhance Antitumor Innate Immunity in Radiotherapy, Victoria Valvo, Emanuele Vitale, Marco Tigano, Rachel Evans, Meredith A. Morgan, and Qiang Zhang

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Progranulin Oncogenic Network in Solid Tumors, Elisa Ventura, Giacomo Ducci, Reyes Benot Dominguez, Valentina Ruggiero, Antonino Belfiore, Elena Sacco, Marco Vanoni, Renato V. Iozzo, Antonio Giordano, and Andrea Morrione

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Global Impact of Proteoglycan Science on Human Diseases, Christopher Xie, Liliana Schaefer, and Renato V. Iozzo

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Exploring the Past, Present, and Future of Anti-Angiogenic Therapy in Glioblastoma., Ashley B. Zhang, Khashayar Mozaffari, Brian Aguirre, Victor Li, Rohan Kubba, Nilay C Desai, Darren Wei, Isaac Yang, and Madhuri Wadehra

Manuscripts from 2022

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A mathematical model of GLUT1 modulation in rods and RPE and its differential impact in cell metabolism, Andrea Aparicio, Erika T Camacho, Nancy J. Philp, and Stephen A Wirkus

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Functional determination of calcium-binding sites required for the activation of inositol 1,4,5-trisphosphate receptors, Vikas Arige, Lara E. Terry, Larry E. Wagner, Sundeep Malik, Mariah R. Baker, Guizhen Fan, Suresh K. Joseph, Irina I Serysheva, and David I. Yule

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PI3K Isoform-Specific Regulation of Leader and Follower Cell Function for Collective Migration and Proliferation in Response to Injury, Morgan D Basta, A. Menko, and Janice L Walker

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Fluorescence imaging detection of nanodomain redox signaling events at organellar contacts, David M. Booth, Péter Várnai, Suresh K Joseph, and György Hajnóczky

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OPA1 Modulates Mitochondrial Ca 2+ Uptake Through ER-Mitochondria Coupling, Benjamín Cartes-Saavedra, Josefa Macuada, Daniel Lagos, Duxan Arancibia, María E Andrés, Patrick Yu-Wai-Man, György Hajnóczky, and Verónica Eisner

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Extracellular matrix guidance of autophagy: a mechanism regulating cancer growth, Carolyn Chen and Renato V. Iozzo

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Reduced ER-mitochondria connectivity promotes neuroblastoma multidrug resistance., Jorida Çoku, David M. Booth, Jan Skoda, Madison C Pedrotty, Jennifer Vogel, Kangning Liu, Annette Vu, Erica L Carpenter, Jamie C Ye, Michelle A Chen, Peter Dunbar, Elizabeth Scadden, Taekyung D Yun, Eiko Nakamaru-Ogiso, Estela Area-Gomez, Yimei Li, Kelly C Goldsmith, C Patrick Reynolds, György Hajnóczky, and Michael D Hogarty

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Interferon Gamma Release Assay Mitogen Responses in COVID-19, Dagan Coppock, Claire E. Zurlo, Jenna M. Meloni, Sara L. Goss, John J. Zurlo, and Matthew A. Pettengill

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Glucose Uptake by GLUT1 in Photoreceptors is Essential for Outer Segment Renewal and rod Photoreceptor Survival, Lauren L. Daniele, John Y.S. Han, Ivy S Samuels, Ravikiran Komirisetty, Nikhil Mehta, Jessica L McCord, Minzhong Yu, Yekai Wang, Kathleen Boesze-Battaglia, Brent A Bell, Jianhai Du, Neal S Peachey, and Nancy J. Philp

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Uveitis-mediated immune cell invasion through the extracellular matrix of the lens capsule, JodiRae DeDreu, Sonali Pal-Ghosh, Mary J Mattapallil, Rachel R Caspi, Mary Ann Stepp, and A Sue Menko

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Uveitis-mediated immune cell invasion through the extracellular matrix of the lens capsule., JodiRae DeDreu, Sonali Pal-Ghosh, Mary J Mattapallil, Rachel R Caspi, Mary Ann Stepp, and A Sue Menko