Document Type
Article
Publication Date
7-29-2023
Abstract
Primary adrenal angiosarcoma is an extremely rare malignant tumor with challenging diagnosis. A 66-year-old woman had a 4.3 cm right adrenal mass suspicious for adrenal cortical carcinoma. Pathological examination demonstrated a hemorrhagic adrenal cyst with numerous irregularly shaped anastomosing vascular channels lined by atypical endothelial cells that had frequent atypical mitotic figures (12/10 HPF, Ki67 10%). The tumor cells were positive for CD31, ERG, and FLI-1, but negative for adrenal and other tumor lineage markers by immunohistochemistry. NGS fusion gene testing ruled out epithelioid hemangioendothelioma. Accurate diagnosis and differential inclusion are important for appropriate treatment of this rare tumor.
Recommended Citation
Naeem, Zunaira; Leong, Joon Yau; Morton, Arianna; Hrizat, Alaa; Shiffrin, Eric; Gomella, Andrew; McCue, Peter; Mann, Mark; and Li, Li, "Primary Adrenal Angiosarcoma: A Case Report and Review of the Literature" (2023). Department of Pathology, Anatomy, and Cell Biology Faculty Papers. Paper 407.
https://jdc.jefferson.edu/pacbfp/407
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.
Language
English
Comments
This article is the author's final published version in Urology Case Reports, Volume 50, September 2023, Article number 102513.
The published version is available at https://doi.org/10.1016/j.eucr.2023.102513. Copyright © 2023 The Authors. Published by Elsevier Inc.