Manuscripts from 2024
Downregulation of PIEZO2 in the Detrusor of Men With Bladder Outlet Obstruction and Its Association With Urinary Retention and Decreased Bladder Compliance, Carlos Henrique Suzuki Bellucci, Thiago Souto Hemerly, Luisa Resende Tenório de Albuquerque, Ruan Pimenta, Vanessa Guimaraes Schreiter, Sabrina Thalita dos Reis, Jose de Bessa Jr, Katia Ramos Moreira Leite, Alberto Antunes, Boopathi Ettickan, William C. Nahas, and Cristiano Mendes Gomes
Molecular Mechanism of Bitter Taste Receptor Agonist-Mediated Relaxation of Airway Smooth Muscle, Stanley Conaway, Weiliang Huang, Miguel A. Hernandez-Lara, Maureen A. Kane, Raymond B. Penn, and Deepak A. Deshpande
Heated Tobacco Product Iqos Induces Unique Metabolic Signatures in Human Bronchial Epithelial Cells, Erin O. Curley, Omran Abu Aboud, Kenneth J. Chmiel, Ajay P. Nayak, Oliver Fiehn, Amir A. Zeki, and Pawan Sharma
Inhibiting Endothelial Cell Mst1 Attenuates Acute Lung Injury in Mice, Zhi-fu Guo, Nopprarat Tongmuang, Chao Li, Chen Zhang, Louis Hu, Daniel Capreri, Mei-Xing Zuo, Ross Summer, and Jianxin Sun
Nur77 Mitigates Endothelial Dysfunction Through Activation of Both Nitric Oxide Production and Anti-Oxidant Pathways, Lin Lu, Soohwa Jang, Jiaqi Zhu, Qing Qin, Lijun Sun, and Jianxin Sun
Manuscripts from 2023
Interleukin 31 Receptor α Promotes Smooth Muscle Cell Contraction and Airway Hyperresponsiveness in Asthma, Santhoshi Akkenepally, Dan Yombo, Sanjana Yerubandi, Geereddy Bhanuprakash Reddy, Deepak Deshpande, Francis McCormack, and Satish Madala
Mst1-Mediated Phosphorylation of Nur77 Improves the Endometrial Receptivity in Human and Mice, Xinyu Cai, Yue Jiang, Zhiwen Cao, Mei Zhang, Na Kong, Lina Yu, Yedong Tang, Shuangbo Kong, Wenbo Deng, Haibin Wang, Jianxin Sun, Lijun Ding, Ruiwei Jiang, Haixiang Sun, and Guijun Yan
Reactive Oxygen Species Behaving Badly: Oxidized Phosphatidylcholines Corrupt Ca2+ Signaling in Airway Smooth Muscle, Deepak A. Deshpande and Raymond B. Penn
Crosstalk Between Diacylglycerol Kinase and Protein Kinase a in the Regulation of Airway Smooth Muscle Cell Proliferation, Miguel Angel Hernandez-Lara; Santosh Kumar Yadav; Stanley Conaway; Sushrut D. Shah; Raymond B. Penn, PhD; and Deepak A. Deshpande, PhD
Comparison of the Biological Basis for Non-HIV Transmission to HIV-Exposed Seronegative Individuals, Disease Non-Progression in HIV Long-Term Non-Progressors and Elite Controllers, Joseph Hokello, Priya Tyagi, Shelly Dimri, Adhikarimayum Lakhikumar Sharma, and Mudit Tyagi
Epicutaneous Sensitization to the Phytocannabinoid β-Caryophyllene Induces Pruritic Inflammation, Saadet Inan, Sara J Ward, Citlalli T Baltazar, Gabrielle A. Peruggia, Elham Javed, and Ajay P. Nayak
Reclaiming the Balance: Blocking Glutamine Uptake to Restrain Pulmonary Fibrosis, Gang Liu and Ross Summer
Proteomics-Based Approach for Detailing the Allergenic Profile of Cannabis Chemotypes, Cali Loblundo, Jenna Severa, Gabrielle A Peruggia, Kristina Reid Black, Suman Chandra, Hemant Lata, Mahmoud ElSohly, Martin D Chapman, Deepak A. Deshpande, and Ajay P. Nayak
Comparing Performance of Spectral Image Analysis Approaches for Detection of Cellular Signals in Time-Lapse Hyperspectral Imaging Fluorescence Excitation-Scanning Microscopy, Marina Parker, Naga S. Annamdevula, Donald Pleshinger, Zara Ijaz, Josephine Jalkh, Raymond Penn, Deepak Deshpande, Thomas C. Rich, and Silas J. Leavesley
The Effects of Dual IQOS and Cigarette Smoke Exposure on Airway Epithelial Cells: Implications for Lung Health and Respiratory Disease Pathogenesis, Pritam Saha, Siddhi Jain, Ipsita Mukherjee, Samir R. Panda, Amir A. Zeki, V.G.M. Naidu, and Pawan Sharma
An Entosis-Like Process Induces Mitotic Disruption in Pals1 Microcephaly Pathogenesis, Noelle A Sterling, Jun Young Park, Raehee Park, Seo-Hee Cho, and Seonhee Kim
PKCε Activator Protects Hippocampal Microvascular Disruption and Memory Defect in 3×Tg-Alzheimer's Disease Mice with Cerebral Microinfarcts, Huaixing Wang, Zongxiu Zhang, and Jarin Hongpaisan
Editorial: Debates in Cardiovascular Pharmacology and Drug Discovery: 2022, Keman Xu, Fatma Saaoud, Ying Shao, Yifan Lu, Xiaohua Jiang, Sheng Wu, Jianxin Sun, Filipe Fernades Conti, Laisel Martinez, Roberto Vazquez-Padron, Hong Wang, and Xiaofeng Yang
Abaloparatide Maintains Normal Rat Blood Calcium Level in Part Via 1,25-Dihydroxyvitamin D/osteocalcin Signaling Pathway, Yanmei Yang, Wei-Ju Louis Tseng, and Bin Wang
Manuscripts from 2022
Regulation of Oxidative Phosphorylation of Liver Mitochondria in Sepsis, Pierre Eyenga, Benjamin Rey, Lilia Eyenga, and Shey-Shing Sheu
Regulation of Airway Smooth Muscle Cell Proliferation by Diacylglycerol Kinase: Relevance to Airway Remodeling in Asthma, Miguel Angel Hernandez-Lara; Santosh K Yadav; Sushrut D. Shah; Mariko Okumura; Yuichi Yokoyama; Raymond B. Penn,; Taku Kambayashi; and Deepak A. Deshpande
29 m 6 A-RNA Methylation (Epitranscriptomic) Regulators Are Regulated in 41 Diseases including Atherosclerosis and Tumors Potentially via ROS Regulation - 102 Transcriptomic Dataset Analyses, Ming Liu, Keman Xu, Fatma Saaoud, Ying Shao, Ruijing Zhang, Yifan Lu, Yu Sun, Charles Drummer IV, Li Li, Sheng Wu, Satya P Kunapuli, Gerard J Criner, Jianxin Sun, Huimin Shan, Xiaohua Jiang, Hong Wang, and Xiaofeng Yang
Aorta in Pathologies May Function as an Immune Organ by Upregulating Secretomes for Immune and Vascular Cell Activation, Differentiation and Trans-Differentiation-Early Secretomes may Serve as Drivers for Trained Immunity, Yifan Lu, Yu Sun, Keman Xu, Fatma Saaoud, Ying Shao, Charles Drummer, Sheng Wu, Wenhui Hu, Jun Yu, Satya P Kunapuli, John R Bethea, Roberto I Vazquez-Padron, Jianxin Sun, Xiaohua Jiang, Hong Wang, and Xiaofeng Yang
PKCε Activation Restores Loss of PKCε, Manganese Superoxide Dismutase, Vascular Endothelial Growth Factor, and Microvessels in Aged and Alzheimer's Disease Hippocampus, Guetchyn Millien, Huaixing Wang, Zongxiu Zhang, Dan L Alkon, and Jarin Hongpaisan
Piperine Attenuates Cigarette Smoke-Induced Oxidative Stress, Lung Inflammation, and Epithelial-Mesenchymal Transition by Modulating the SIRT1/Nrf2 Axis, Pritam Saha, Sneha Durugkar, Siddhi Jain, P A Shantanu, Samir R Panda, Aishwarya Jala, Sharad Gokhale, Pawan Sharma, and V G M Naidu
Retraction Note: Obesity-induced adipokine imbalance impairs mouse pulmonary vascular endothelial function and primes the lung for injury, Dilip Shah, Freddy Romero, Michelle Duong, Nadan Wang, Bishnuhari Paudyal, Benjamin T Suratt, Caleb B Kallen, Jianxin Sun, Ying Zhu, Kenneth Walsh, and Ross Summer
Ovarian cancer G protein-coupled receptor 1 inhibits A549 cells migration through casein kinase 2α intronless gene and neutral endopeptidase, Adhikarimayum Lakhikumar Sharma, Puyam Milan Meitei, Takhellambam Chanu Machathoibi, Naorem Tarundas Singh, Thiyam Ramsing Singh, and Lisam Shanjukumar Singh
Cocaine Sensitizes the CD4+ T Cells for HIV Infection by Co-stimulating NFAT and Ap-1, Adhikarimayum Lakhikumar Sharma, Dylan Shafer, Daniel Netting, and Mudit Tyagi
Crossroads of Drug Abuse and HIV Infection: Neurotoxicity and CNS Reservoir, Shilpa Sonti, Kratika Tyagi, Amit Pande, René Daniel, Adhikarimayum Lakhikumar Sharma, and Mudit Tyagi
AKT inhibition in the central nervous system induces signaling defects resulting in psychiatric symptomatology, Apostolia-Maria Tsimberidou, Antonis Skliris, Alan Valentine, Jamie Shaw, Ursula Hering, Henry Hiep Vo, Tung On Chan, Roger S Armen, Jeffrey R Cottrell, Jen Q Pan, and Philip N Tsichlis
Abi1 mediates airway smooth muscle cell proliferation and airway remodeling via Jak2/STAT3 signaling, Ruping Wang; Yinna Wang; Guoning Liao; Bohao Chen; Reynold A. Panettieri, Jr.; Raymond B. Penn; and Albany Medical College
Manuscripts from 2021
An update on the hiv dna vaccine strategy, Joseph Hokello, Adhikarimayum Lakhikumar Sharma, and Mudit Tyagi
AP-1 and NF-κB synergize to transcriptionally activate latent HIV upon T-cell receptor activation., Joseph Hokello, Adhikarimayum Lakhikumar Sharma, and Mudit Tyagi
Combinatorial use of both epigenetic and non-epigenetic mechanisms to efficiently reactivate hiv latency, Joseph Hokello, Adhikarimayum Lakhikumar Sharma, and Mudit Tyagi
Enlightening Ways to Relax Airway Smooth Muscle: Opsins., Vera P. Krymskaya and Raymond B. Penn
Statins in patients with COVID-19: a retrospective cohort study in Iranian COVID-19 patients., Payam Peymani, Tania Dehesh, Farnaz Aligolighasemabadi, Mohammadamin Sadeghdoust, Katarzyna Kotfis, Mazaher Ahmadi, Parvaneh Mehrbod, Pooya Iranpour, Sanaz Dastghaib, Ahmad Nasimian, Amir Ravandi, Biniam Kidane, Naseer Ahmed, Pawan Sharma, Shahla Shojaei, Kamran Bagheri Lankarani, Andrzej Madej, Nima Rezaei, Tayyebeh Madrakian, Marek J Los, Hagar Ibrahim Labouta, Pooneh Mokarram, and Saeid Ghavami
Micro-Computed Tomographic Analysis of the Shaping Ability of XP-Endo Shaper in Oval-Shaped Distal Root Canals of Mandibular Molars, Ane Poly, Wei-Ju Louis Tseng, Fernando Marques, Frank Carsten Setzer, and Bekir Karabucak
Emerging Advances of Nanotechnology in Drug and Vaccine Delivery against Viral Associated Respiratory Infectious Diseases (VARID), Amir Seyfoori, Mahdieh Shokrollahi Barough, Pooneh Mokarram, Mazaher Ahmadi, Parvaneh Mehrbod, Alireza Sheidary, Tayyebeh Madrakian, Mohammad Kiumarsi, Tavia Walsh, Kielan D McAlinden, Chandra C Ghosh, Pawan Sharma, Amir A Zeki, Saeid Ghavami, and Mohsen Akbari
Circumcision as an Intervening Strategy against HIV Acquisition in the Male Genital Tract, Adhikarimayum Lakhikumar Sharma, Joseph Hokello, and Mudit Tyagi
Autophagy, Apoptosis, the Unfolded Protein Response, and Lung Function in Idiopathic Pulmonary Fibrosis, Pawan Sharma, Javad Alizadeh, Maya Juarez, Afshin Samali, Andrew J Halayko, Nicholas J Kenyon, Saeid Ghavami, and Amir A Zeki
Chloroquine: Autophagy inhibitor, antimalarial, bitter taste receptor agonist in fight against COVID-19, a reality check?, Pawan Sharma, Kielan D. McAlinden, Saeid Ghavami, and Deepak A. Deshpande
HIV-1 persistence in the CNS: Mechanisms of latency, pathogenesis and an update on eradication strategies., Shilpa Sonti, Adhikarimayum Lakhikumar Sharma, and Mudit Tyagi
Manuscripts from 2020
The ER Stress/UPR Axis in Chronic Obstructive Pulmonary Disease and Idiopathic Pulmonary Fibrosis., Mahmoud Aghaei, Sanaz Dastghaib, Sajjad Aftabi, Mohamad-Reza Aghanoori, Javad Alizadeh, Pooneh Mokarram, Parvaneh Mehrbod, Milad Ashrafizadeh, Ali Zarrabi, Kielan Darcy McAlinden, Mathew Suji Eapen, Sukhwinder Singh Sohal, Pawan Sharma, Amir A Zeki, and Saeid Ghavami
Shedding Light on the Role of Extracellular Vesicles in HIV Infection and Wound Healing., Aseel Alqatawni, Adhikarimayum Lakhikumar Sharma, Beatrice Attilus, Mudit Tyagi, and Rene Daniel
Simvastatin Induces Unfolded Protein Response and Enhances Temozolomide-Induced Cell Death in Glioblastoma Cells., Sanaz Dastghaib, Shahla Shojaei, Zohreh Mostafavi-Pour, Pawan Sharma, John B Patterson, Afshin Samali, Pooneh Mokarram, and Saeid Ghavami
Interleukin 35 Delays Hindlimb Ischemia-Induced Angiogenesis Through Regulating ROS-Extracellular Matrix but Spares Later Regenerative Angiogenesis., Hangfei Fu, Yu Sun, Ying Shao, Jason Saredy, Ramon Cueto, Lu Liu, Charles Drummer, Candice Johnson, Keman Xu, Yifan Lu, Xinyuan Li, Shu Meng, Eric R Xue, Judy Tan, Nirag C Jhala, Daohai Yu, Yan Zhou, Kayla J Bayless, Jun Yu, Thomas J Rogers, Wenhui Hu, Nathaniel W Snyder, Jianxin Sun, Xuebin Qin, Xiaohua Jiang, Hong Wang, and Xiaofeng Yang
A narrative review on the basic and clinical aspects of the novel SARS-CoV-2, the etiologic agent of COVID-19., Joseph Hokello, Adhikarimayum Lakhikumar Sharma, Girish C. Shukla, and Mudit Tyagi
Efficient Non-Epigenetic Activation of HIV Latency through the T-Cell Receptor Signalosome., Joseph Hokello, Adhikarimayum Lakhikumar Sharma, and Mudit Tyagi
The odorant receptor OR2W3 on airway smooth muscle evokes bronchodilation via a cooperative chemosensory tradeoff between TMEM16A and CFTR., Jessie Huang, Hong Lam, Cynthia Koziol-White, Nathachit Limjunyawong, Donghwa Kim, Nicholas Kim, Nikhil Karmacharya, Premraj Rajkumar, Danielle Firer, Nicholas M Dalesio, Joseph Jude, Richard C Kurten, Jennifer L Pluznick, Deepak A. Deshpande, Raymond B Penn, Stephen B Liggett, Reynold A Panettieri, Xinzhong Dong, and Steven S An
The short variant of optic atrophy 1 (OPA1) improves cell survival under oxidative stress., Hakjoo Lee, Sylvia B Smith, Shey-Shing Sheu, and Yisang Yoon
The Generation of an Engineered Interleukin-10 Protein With Improved Stability and Biological Function, Faisal Minshawi, Sebastian Lanvermann, Edward McKenzie, Rebecca Jeffery, Kevin Couper, Stamatia Papoutsopoulou, Axel Roers, and Werner Muller
Electrophysiological properties of the mitochondrial permeability transition pores: Channel diversity and disease implication., M. A. Neginskaya, E. V. Pavlov, and S.-S. Sheu
Reversing Heart Failure With a Ventricular Anchoring Device: Another Hope for Myopathic Mitral Regurgitation., J. Eduardo Rame
Mitochondrial Quality Control in Age-Related Pulmonary Fibrosis., Willy Roque, Karina Cuevas-Mora, and Freddy Romero
CBF-1 Promotes the Establishment and Maintenance of HIV Latency by Recruiting Polycomb Repressive Complexes, PRC1 and PRC2, at HIV LTR., Adhikarimayum Lakhikumar Sharma, Joseph Hokello, Shilpa Sonti, Sonia Zicari, Lin Sun, Aseel Alqatawni, Michael Bukrinsky, Gary Simon, Ashok Chauhan, René Daniel, and Mudit Tyagi
DNA dependent protein kinase (DNA-PK) enhances HIV transcription by promoting RNA polymerase II activity and recruitment of transcription machinery at HIV LTR., Sonia Zicari, Adhikarimayum Lakhikumar Sharma, Geetaram Sahu, Larisa Dubrovsky, Lin Sun, Han Yue, Tejaswi Jada, Alex Ochem, Gary Simon, Michael Bukrinsky, and Mudit Tyagi
Manuscripts from 2019
The histone deacetylase inhibitor tubacin mitigates endothelial dysfunction by up-regulating the expression of endothelial nitric oxide synthase., Jihui Chen, Jian Zhang, Noor F. Shaik, Bing Yi, Xin Wei, Xiao-Feng Yang, Ulhas P. Naik, Ross Summer, Guijun Yan, Xinyun Xu, and Jianxin Sun
Mechanisms of simvastatin myotoxicity: The role of autophagy flux inhibition., Arya Emami, Shahla Shojaei, Simone C. da Silva Rosa, Mahmoud Aghaei, Ehsan Samiei, Amir Reza Vosoughi, Forouh Kalantari, Philip Kawalec, James Thliveris, Pawan Sharma, Amir A. Zeki, Mohsen Akbari, Joseph W. Gordon, and Saeid Ghavami
C1q/TNF-related protein 3 (CTRP3) and 9 (CTRP9) concentrations are decreased in patients with heart failure and are associated with increased morbidity and mortality., Chao Gao, Shasha Zhao, Kun Lian, Baibing Mi, Rui Si, Zhijun Tan, Feng Fu, Shuai Wang, Rutao Wang, Xin-Liang Ma, and Ling Tao
Insights into the HIV Latency and the Role of Cytokines., Joseph Hokello, Adhikarimayum Lakhikumar Sharma, Manjari Dimri, and Mudit Tyagi
Lipid Uptake by Alveolar Macrophages Drives Fibrotic Responses to Silica Dust., Xiaomin Hou, Ross Summer, Ziying Chen, Ying Tian, Jingjing Ma, Jie Cui, Xiaohui Hao, Lingli Guo, Hong Xu, Hongli Wang, and Heliang Liu
SPG7 targets the m-AAA protease complex to process MCU for uniporter assembly, Ca2 influx, and regulation of mitochondrial permeability transition pore opening, Stephen Hurst, Ariele Baggett, György Csordás, and Shey-Shing Sheu
Inflammatory Serine Proteases Play a Critical Role in the Early Pathogenesis of Diabetic Cardiomyopathy., Mikhail A Kolpakov, Kunal Sikder, Amrita Sarkar, Shaswati Chaki, Sanket K Shukla, Xinji Guo, Zhao Qi, Carlos Barbery, Abdelkarim Sabri, and Khadija Rafiq
Twenty Novel Disease Group-Specific and 12 New Shared Macrophage Pathways in Eight Groups of 34 Diseases Including 24 Inflammatory Organ Diseases and 10 Types of Tumors., Bin Lai, Jiwei Wang, Alexander Fagenson, Yu Sun, Jason Saredy, Yifan Lu, Gayani Nanayakkara, William Y Yang, Daohai Yu, Ying Shao, Charles Drummer, Candice Johnson, Fatma Saaoud, Ruijing Zhang, Qian Yang, Keman Xu, Kevin Mastascusa, Ramon Cueto, Hangfei Fu, Susu Wu, Lizhe Sun, Peiqian Zhu, Xuebin Qin, Jun Yu, Daping Fan, Ying H Shen, Jianxin Sun, Thomas Rogers, Eric T Choi, Hong Wang, and Xiaofeng Yang
Increasing Upstream Chromatin Long-Range Interactions May Favor Induction of Circular RNAs in LysoPC-Activated Human Aortic Endothelial Cells., Angus Li, Yu Sun, Charles Drummer, Yifan Lu, Daohai Yu, Yan Zhou, Xinyuan Li, Simone J. Pearson, Candice Johnson, Catherine Yu, William Y. Yang, Kevin Mastascusa, Xiaohua Jiang, Jianxin Sun, Thomas Rogers, Wenhui Hu, Hong Wang, and Xiaofeng Yang
Glucocorticoids and Airway Smooth Muscle: A Few More Answers, Still More Questions, Ajay P. Nayak
Bitter Taste Receptors for Asthma Therapeutics., Ajay P. Nayak, Sushrut D. Shah, James V. Michael, and Deepak A. Deshpande
Matrix metalloproteinase activity in the lung is increased in Hermansky-Pudlak syndrome., Ross Summer, Rachana Krishna, DeLeila Schriner, Karina Cuevas-Mora, Dominic Sales, Rachel Para, Jesse Roman, Carl Nieweld, Bernadette R. Gochuico, and Freddy Romero
Manuscripts from 2018
Apoptosis signal-regulating kinase 1 inhibition attenuates human airway smooth muscle growth and migration in chronic obstructive pulmonary disease., Mathew S. Eapen, Anudeep Kota, Howard Vindin, Kielan D. McAlinden, Dia Xenaki, Brian G. Oliver, Deepak A. Deshpande, Sukhwinder Singh Sohal, and Pawan Sharma
NKX2-1-AS1 negatively regulates CD274/PD-L1, cell-cell interaction genes, and limits human lung carcinoma cell migration., Hasmeena Kathuria, Guetchyn Millien, Liam McNally, Adam C. Gower, Jean-Bosco Tagne, Yuxia Cao, and Maria I. Ramirez
New targets for resolution of airway remodeling in obstructive lung diseases., Ajay P. Nayak, Deepak A. Deshpande, and Raymond B. Penn
Pepducins as a potential treatment strategy for asthma and COPD., Reynold A. Panettieri, Tonio Pera, Stephen B B. Liggett, Jeffrey L. Benovic, and Raymond B. Penn
High Fat Diet Upregulates Fatty Acid Oxidation and Ketogenesis via Intervention of PPAR-γ., Kunal Sikder, Sanket Kumar Shukla, Neel Patel, Harpreet Singh, and Khadija Rafiq
α-Catenin-dependent cytoskeletal tension controls Yap activity in the heart., Alexia Vite, Caimei Zhang, Roslyn Yi, Sabrina Emms, and Glenn L. Radice
Transcriptional up-regulation of relaxin-3 by Nur77 attenuates β-adrenergic agonist-induced apoptosis in cardiomyocytes., Xiaohua You, Zhifu Guo, Fang Cheng, Bing Yi, Fan Yang, Xinzhu Liu, Ni Zhu, Xianxian Zhao, Guijun Yan, Xin-Liang Ma, and Jianxin Sun
Pim-1 Kinase Phosphorylates Cardiac Troponin I and Regulates Cardiac Myofilament Function., Ni Zhu, Bing Yi, Zhifu Guo, Guanxin Zhang, Shengdong Huang, Yongwen Qin, Xianxian Zhao, and Jianxin Sun
Manuscripts from 2017
The Mitochondrial Ca(2+) Uniporter: Structure, Function, and Pharmacology., Jyotsna Mishra, Bong Sook Jhun, Stephen Hurst, Jin O-Uchi, György Csordás, and Shey-Shing Sheu
Obesity-induced Endoplasmic Reticulum Stress Causes Lung Endothelial Dysfunction and Promotes Acute Lung Injury, Dilip Shah, Freddy Romero, Zhi Guo, Jianxin Sun, Jonathan C. Li, Caleb Kallen, Ulhas P. Naik, and Ross Summer
Autophagy and airway fibrosis: Is there a link?, Pawan K. Sharma, Anudeep Kota, Deepak A. Deshpande, Mehra Haghi, and Brian G. Oliver
HMGCS2 is a key ketogenic enzyme potentially involved in type 1 diabetes with high cardiovascular risk., Sanket Kumar Shukla, Weijing Liu, Kunal Sikder, Sankar Addya, Amrita Sarkar, Yidong Wei, and Khadija Rafiq
Endothelium in the pharyngeal arches 3, 4 and 6 is derived from the second heart field., Xia Wang, Dongying Chen, Kelley Chen, Ali Jubran, AnnJosette Ramirez, and Sophie Astrof
Ixazomib enhances parathyroid hormone-induced β-catenin/T-cell factor signaling by dissociating β-catenin from the parathyroid hormone receptor., Yanmei Yang, Hong Lei, Ya-Wei Qiang, and Bin Wang
miR-181a increases FoxO1 acetylation and promotes granulosa cell apoptosis via SIRT1 downregulation., Mei Zhang, Qun Zhang, Yali Hu, Lu Xu, Yue Jiang, Chunxue Zhang, Lijun Ding, Ruiwei Jiang, Jianxin Sun, Haixiang Sun, and Guijun Yan
Manuscripts from 2015
Pleiotropic Effects of Bitter Taste Receptors on [Ca2+]i Mobilization, Hyperpolarization, and Relaxation of Human Airway Smooth Muscle Cells., Blanca Camoretti-Mercado; Susan H Pauer; Hwan Mee Yong; Dan'elle C Smith; Deepak A. Deshpande, PhD; Steven S An; and Stephen B Liggett
Akt kinase C-terminal modifications control activation loop dephosphorylation and enhance insulin response., Tung O. Chan, Jin Zhang, Brian C. Tiegs, Brian Blumhof, Linda Yan, Nikhil Keny, Morgan Penny, Xue Li, John M. Pascal, Roger S. Armen, Ulrich Rodeck, and Raymond B. Penn
Isoform-specific dynamic translocation of PKC by α1-adrenoceptor stimulation in live cells., Jin O-Uchi, Jaime Sorenson, Bong Sook Jhun, Jyotsna Mishra, Stephen Hurst, Kaleef Williams, Shey-Shing Sheu, and Coeli M.B. Lopes
miR-146a targets Fos expression in human cardiac cells., Xavier Palomer, Eva Capdevila-Busquets, Gaia Botteri, Mercy M Davidson, Cristina Rodríguez, José Martínez-González, Francisco Vidal, Emma Barroso, Tung O Chan, Arthur M Feldman, and Manuel Vázquez-Carrera
Obesity-induced adipokine imbalance impairs mouse pulmonary vascular endothelial function and primes the lung for injury., Dilip Shah, Freddy Romero, Michelle Duong, Nadan Wang, Bishnuhari Paudyal, Benjamin T Suratt, Caleb B Kallen, Jianxin Sun, Ying Zhu, Kenneth Walsh, and Ross Summer
New functions for alpha-catenins in health and disease: from cancer to heart regeneration., Alexia Vite, Jifen Li, and Glenn L. Radice
Orphan Nuclear Receptor Nur77 Inhibits Cardiac Hypertrophic Response to Beta-Adrenergic Stimulation., Guijun Yan, Ni Zhu, Shengdong Huang, Bing Yi, Xiying Shang, Ming Chen, Nadan Wang, Guan-Xin Zhang, Jennifer A Talarico, Douglas G Tilley, Erhe Gao, and Jianxin Sun
Manuscripts from 2014
Anti-mitogenic effects of bitter taste receptor (BTR) agonists on human airway smooth muscle cells, Deepak A. Deshpande, PhD
Genetic modulation of the SERCA activity does not affect the Ca(2+) leak from the cardiac sarcoplasmic reticulum., Satoshi Morimoto, Kenichi Hongo, Yoichiro Kusakari, Kimiaki Komukai, Makoto Kawai, Jin O-Uchi, Hiroyuki Nakayama, Michio Asahi, Kinya Otsu, Michihiro Yoshimura, and Satoshi Kurihara
Adrenergic Signaling Regulates Mitochondrial Ca(2+) Uptake Through Pyk2-Dependent Tyrosine Phosphorylation of the Mitochondrial Ca(2+) Uniporter., Jin O-Uchi, Bong Sook Jhun, Shangcheng Xu, Stephen Hurst, Anna Raffaello, Xiaoyun Liu, Bing Yi, Huiliang Zhang, Polina Gross, Jyotsna Mishra, Alina Ainbinder, Sarah Kettlewell, Godfrey L Smith, Robert T Dirksen, Wang Wang, Rosario Rizzuto, and Shey-Shing Sheu
Cardiac calcium handling on trial: targeting the failing cardiomyocyte signalosome., Sven T Pleger, Philip Raake, Hugo A Katus, and Patrick Most
Shape and position of the node and notochord along the bilateral plane of symmetry are regulated by cell-extracellular matrix interactions., Maria Pulina, Dong Liang, and Sophie Astrof
Glutathione: A possible link to autophagy in systemic lupus erythematosus, Dilip Shah and Swapan K. Nath
Plasma Adiponectin, Clinical Factors, and Patient Outcomes during the Acute Respiratory Distress Syndrome., Allan J Walkey, Serkalem Demissie, Dilip Shah, Freddy Romero, Leah Puklin, and Ross S Summer
Manuscripts from 2013
Nesfatin-1 activates cardiac vagal neurons of nucleus ambiguus and elicits bradycardia in conscious rats., G Cristina Brailoiu, Elena Deliu, Andrei A Tica, Joseph E Rabinowitz, Douglas G Tilley, Khalid Benamar, Walter J Koch, and Eugen Brailoiu
Cavin1; a regulator of lung function and macrophage phenotype., Praveen Govender, Freddy Romero, Dilip Shah, Jesus Paez, Shi-Ying Ding, Libin Liu, Adam Gower, Elizabeth Baez, Sherif Shawky Aly, Paul Pilch, and Ross Summer
Glucose stimulation induces dynamic change of mitochondrial morphology to promote insulin secretion in the insulinoma cell line INS-1E., Bong Sook Jhun, Hakjoo Lee, Zheng-Gen Jin, and Yisang Yoon
