Follow

Manuscripts from 2024

PDF

CYP26A1 Links WNT and Retinoic Acid Signaling: A Target to Differentiate ALDH+ Stem Cells in APC-Mutant CRC, Caroline O.B. Facey, Victoria O. Hunsu, Chi Zhang, Brian Osmond, Lynn M. Opdenaker, and Bruce M. Boman

PDF

A Cyclin D1 Intrinsically Disordered Domain Accesses Modified Histone Motifs to Govern Gene Transcription, Xuanmao Jiao, Gabriele Di Sante, Mathew Casimiro, Agnes Tantos, Anthony Ashton, Zhiping Li, Yen Quach, Dharmendra Bhargava, Agnese Di Rocco, Claudia Pupo, Marco Crosariol, Tamas Lazar, Peter Tompa, Chenguang Wang, Zuoren Yu, Zhao Zhang, Kawthar Aldaaysi, Ratna Vadlamudi, Monica Mann, Emmanuel Skordalakes, Andrew Kossenkov, Yanming Du, and Richard Pestell

Submissions from 2023

PDF

The Concise Guide to PHARMACOLOGY 2023/24: Catalytic Receptors, Stephen P.H. Alexander, Doriano Fabbro, Eamonn Kelly, Alistair A. Mathie, John A. Peters, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Jamie A. Davies, Annie Beuve, Peter Brouckaert, Clare Bryant, John C. Burnett, Richard W. Farndale, Andreas Friebe, John Garthwaite, Adrian J. Hobbs, Gavin E. Jarvis, Doris Koesling, Michaela Kuhn, David MacEwan, Tom P. Monie, Lincoln R. Potter, Michael Russwurm, Harald H.H.W. Schmidt, Johannes-Peter Stasch, and Scott A. Waldman

PDF

Kinome Profiling Identifies MARK3 and STK10 as Potential Therapeutic Targets in Uveal Melanoma, Usman Baqai, Alison M. Kurimchak, Isabella Trachtenberg, Timothy J. Purwin, Jelan I. Haj, Anna Han, Kristine Luo, Nikole Fandino Pachon, Angela Jeon, Vivian Chua, Michael A. Davies, J Silvio Gutkind, Jeffrey L. Benovic, James S. Duncan, and Andrew E. Aplin

PDF

Enteroendocrine Cell Regulation of the Gut-Brain Axis, Joshua Barton, Annie Londregan, Tyler Alexander, Ariana Entezari, Manuel Covarrubias, and Scott Waldman

PDF

Intestinal Neuropod Cell GUCY2C Regulates Visceral Pain, Joshua R. Barton, Annie K. Londregran, Tyler D. Alexander, Ariana A. Entezari, Shely Bar-Ad, Lan Cheng, Angelo C. Lepore, Adam E. Snook, Manuel Covarrubias, and Scott A. Waldman

PDF

27-hydroxycholesterol and DNA Damage Repair: Implication in Prostate Cancer, Gloria Cecilia Galvan, Nadine Friedrich, Sanjay Das, James Daniels, Sara Pollan, Shweta Dambal, Ryusuke Suzuki, Sergio Sanders, Sungyong You, Hisashi Tanaka, Yeon-Joo Lee, Wei Yuan, Johann de Bono, Irina Vasilevskaya, Karen Knudsen, Michael Freeman, and Stephen Freedland

PDF

Co-Targeting FASN and mTOR Suppresses Uveal Melanoma Growth, Anna Han, Dzmitry Mukha, Vivian Chua, Timothy J. Purwin, Manoela Tiago, Bhavik Modasia, Usman Baqai, Jenna Aumiller, Nelisa Bechtel, Emily Hunter, Meggie Danielson, Mizue Terai, Philip B. Wedegaertner, Takami Sato, Solange Landreville, Michael A. Davies, Stefan Kurtenbach, William J. Harbour, Zachary T. Schug, and Andrew E. Aplin

PDF

Needle Biopsy Accelerates Pro-metastatic Changes and Systemic Dissemination in Breast Cancer: Implications for Mortality by Surgery Delay, Hiroyasu Kameyama, Priya Dondapati, Reese Simmons, Macall Leslie, John Langenheim, Yunguang Sun, Misung Yi, Aubrey Rottschaefer, Rashmi Pathak, Shreya Nuguri, Kar-Ming Fung, Shirng-Wern Tsaih, Inna Chervoneva, Hallgeir Rui, and Takemi Tanaka

PDF

A Review of IsomiRs in Colorectal Cancer, Molly A. Lausten and Bruce M. Boman

PDF

Desmoglein-2 as a Cancer Modulator: Friend or Foe?, Kay Myo Min, Charlie Ffrench, Barbara McClure, Michael Ortiz, Emma Dorward, Michael Samuel, Lisa Ebert, Mỹ Mahoney, and Claudine Bonder

PDF

Comparison of Bacterial Culture With Biofire® Filmarray® Multiplex PCR Screening of Archived Cerebrospinal Fluid Specimens From Children With Suspected Bacterial Meningitis in Nigeria, S Obaro, F Hassan-Hanga, N Medugu, Rasaq Olaosebikan, G Olanipekun, B Jibir, S Gambo, Theresa Ajose, Carissa Duru, B Ebruke, and H D Davies

Gene Signature Reveals Decreased SOX10-Dependent Transcripts in Malignant Cells From Immune Checkpoint Inhibitor-Resistant Cutaneous Melanomas, Timothy J. Purwin, Signe Caksa, Ahmet Sacan, Claudia Capparelli, and Andrew E. Aplin

PDF

Targeting the αvβ3/NGR2 Pathway in Neuroendocrine Prostate Cancer, Anna Testa, Fabio Quaglia, Nicole M. Naranjo, Cecilia E. Verrillo, Christopher D. Shields, Stephen Lin, Maxwell W. Pickles, Drini F. Hamza, Tami Von Schalscha, David A. Cheresh, Benjamin E Leiby, Qin Liu, Jianyi Ding, William K. Kelly, D. Craig Hooper, Eva Corey, Edward F. Plow, Dario C. Altieri, and Lucia R. Languino

PDF

Parkin Ubiquitination of Kindlin-2 Enables Mitochondria-Associated Metastasis Suppression, Minjeong Yeon, Irene Bertolini, Ekta Agarwal, Jagadish C Ghosh, Hsin-Yao Tang, David W. Speicher, Frederick Keeney, Khalid Sossey-Alaoui, Elzbieta Pluskota, Katarzyna Bialkowska, Edward F. Plow, Lucia R. Languino, Emmanuel Skordalakes, M Cecilia Caino, and Dario C. Altieri

PDF

Selection of Optimal Quantile Protein Biomarkers Based on Cell-Level Immunohistochemistry Data, Misung Yi, Tingting Zhan, Amy R. Peck, Jeffrey A. Hooke, Albert J. Kovatich, Craig D. Shriver, Hai Hu, Yunguang Sun, Hallgeir Rui, and Inna Chervoneva

Manuscripts from 2022

PDF

Circulating Messenger RNA Variants as a Potential Biomarker for Surveillance of Hepatocellular Carcinoma, Timothy Block, Daniel Zezulinski, David E. Kaplan, Jingqiao Lu, Samantha Zanine, Tingting Zhan, Cataldo Doria, and Aejaz Sayeed

PDF

A Genome-Wide Screen Identifies PDPK1 as a Target to Enhance the Efficacy of MEK1/2 Inhibitors, Weijia Cai, Nicole A. Wilski, Timothy J. Purwin, Megane Vernon, Manoela Tiago, and Andrew E. Aplin

PDF

The future of targeted kinase inhibitors in melanoma, Signe Caksa, Usman Baqai, and A E Aplin

PDF

Targeting SOX10-deficient cells to reduce the dormant-invasive phenotype state in melanoma, Claudia Capparelli; Timothy J. Purwin; McKenna Glasheen; Signe Caksa; Manoela Tiago; Nicole A. Wilski; Danielle Pomante; Sheera Rosenbaum; Mai Q Nguyen; Weijia Cai; Janusz Franco-Barraza; R. Zheng, MD; Gaurav Kumar; I Chervoneva; Ayako Shimada; Vito W Rebecca; Adam E. Snook; Kim Hookim; Xiaowei Xu; Edna Cukierman; Meenhard Herlyn; and A E Aplin

PDF

Guanylyl cyclase C as a Diagnostic and Therapeutic Target in Colorectal Cancer, Adi Caspi, Ariana A. Entezari, Madison Crutcher, Adam E. Snook, and Scott A. Waldman

PDF

Pharmacologic Ascorbic Acid as Early Therapy for Hospitalized Patients with COVID-19: A Randomized Clinical Trial, Dagan Coppock, Pierre-Christian Violet, Gustavo Vasquez, Katherine Belden, Michael Foster, Bret Mullin, Devon Magee, Isabelle Mikell, Lokesh Shah, Victoria Powers, Brian Curcio, Daniel A. Monti, and Mark Levine

PDF

DNA-PKcs: A Targetable Protumorigenic Protein Kinase., Emanuela Dylgjeri and Karen E Knudsen

PDF

T-Cell Responses to Immunodominant Listeria Epitopes Limit Vaccine-Directed Responses to the Colorectal Cancer Antigen, Guanylyl Cyclase C, John C. Flickinger, Jagmohan Singh, Yanki Yarman, Robert D Carlson, Joshua Barton, Scott A Waldman, and Adam E. Snook

PDF

Ghost mitochondria drive metastasis through adaptive GCN2/Akt therapeutic vulnerability, Jagadish C Ghosh, Michela Perego, Ekta Agarwal, Irene Bertolini, Yuan Wang, Aaron R Goldman, Hsin-Yao Tang, Andrew V Kossenkov, Catherine J Libby, Lucia R Languino, Edward F Plow, Annamaria Morotti, Luisa Ottobrini, Marco Locatelli, David W Speicher, M Cecilia Caino, Joel Cassel, Joseph M Salvino, Marie E Robert, Valentina Vaira, and Dario C Altieri

PDF

Stabilized COre Gene and Pathway Election Uncovers Pan-Cancer Shared Pathways and a Cancer-Specific Driver, Pathum Kossinna, Weijia Cai, Xuewen Lu, Carrie S Shemanko, and Qingrun Zhang

PDF

Functional Assessment of Missense Variants in the ABCC6 Gene Implicated in Pseudoxanthoma Elasticum, a Heritable Ectopic Mineralization Disorder., Luke Kowal, Jianhe Huang, Hongbin Luo, Jagmohan Singh, Adam E Snook, Jouni Uitto, and Qiaoli Li

PDF

Small extracellular vesicle-mediated ITGB6 siRNA delivery downregulates the αVβ6 integrin and inhibits adhesion and migration of recipient prostate cancer cells, Shiv Ram Krishn, Vaughn Garcia, Nicole M Naranjo, Fabio Quaglia, Christopher D Shields, Maisha A Harris, Andrew V Kossenkov, Qin Liu, Eva Corey, Dario C Altieri, and Lucia R Languino

PDF

Lysine Methyltransferase NSD1 and Cancers: Any Role in Melanoma?, Imène Krossa, Thomas Strub, Andrew E Aplin, Robert Ballotti, and Corine Bertolotto

PDF

CTpathway: A Crosstalk-Based Pathway Enrichment Analysis Method for Cancer Research, Haizhou Liu, Mengqin Yuan, Ramkrishna Mitra, Xu Zhou, Min Long, Wanyue Lei, Shunheng Zhou, Yu-E Huang, Fei Hou, Christine M. Eischen, and Wei Jiang

PDF

Spatial Metrics of Interaction between CD163-Positive Macrophages and Cancer Cells and Progression-Free Survival in Chemo-Treated Breast Cancer, Brenton Maisel, Misung Yi, Amy R Peck, Yunguang Sun, Jeffrey A Hooke, Albert J Kovatich, Craig D Shriver, Hai Hu, Marja T Nevalainen, Takemi Tanaka, Nicole L Simone, Li Lily Wang, Hallgeir Rui, and I Chervoneva

PDF

Novel Oncogenic Transcription Factor Cooperation in RB-Deficient Cancer, Amy C. Mandigo, Ayesha A Shafi, Jennifer J McCann, Wei Yuan, Talya Laufer, Denisa Bogdan, Lewis Gallagher, Emanuela Dylgjeri, Galina Semenova, Irina A Vasilevskaya, M J Schiewer, Chris M McNair, Johann S de Bono, and Karen E Knudsen

PDF

A Prospective Cohort Study of the Clinical Predictors of Bacteremia in Under-Five Children With Acute Undifferentiated Fever Attending a Secondary Health Facility in Northwestern Nigeria, Taofik Oluwaseun Ogunkunle, Timothy Olanrewaju Adedoyin, Samuel Kolade Ernest, Fatimah Hassan-Hanga, Abdulazeez Imam, Rasaq Olaosebikan, and Stephen K Obaro

PDF

HOXA9 Overexpression Contributes to Stem Cell Overpopulation That Drives Development and Growth of Colorectal Cancer, Brian Osmond, Caroline O.B. Facey, Chi Zhang, and Bruce M. Boman

PDF

Ondansetron to Reduce Neonatal Opioid Withdrawal Severity: A Randomized Clinical Trial, Gary Peltz, Lauren M. Jansson, Susan Adeniyi-Jones, Carol Cohane, David Drover, Steven Shafer, Meiyue Wang, Manhong Wu, Balaji Govindaswami, Priya Jegatheesan, Cynthia Argani, Salwa Kahn, and Walter K. Kraft

PDF

The NOGO Receptor NgR2, A Novel αVβ3 Integrin Effector, Induces Neuroendocrine Differentiation in Prostate Cancer, Fabio Quaglia, Shiv Ram Krishn, Khalid Sossey-Alaoui, Priyanka Shailendra Rana, Elzbieta Pluskota, Pyung Hun Park, Christopher D. Shields, Stephen Lin, Peter McCue, Andrew V. Kossenkov, Yanqing Wang, David W. Goodrich, Sheng-Yu Ku, Himisha Beltran, William K. Kelly, Eva Corey, Maja Klose, Christine Bandtlow, Qin Liu, Dario C. Altieri, Edward F. Plow, and Lucia R. Languino

PDF

RAS-mediated tumor stress adaptation and the targeting opportunities it presents, Alexandra Redding, A E Aplin, and Elda Grabocka

PDF

Development and Preclinical Investigation of Physically Cross-Linked and pH-Sensitive Polymeric Gels as Potential Vaginal Contraceptives, Ankit K. Rochani, Vivek Agrahari, Neelima Chandra, Onkar N Singh, Timothy J McCormick, Gustavo F Doncel, Meredith R Clark, and Gagan Kaushal

PDF

Targeting gastrointestinal cancers with chimeric antigen receptor (CAR)-T cell therapy, Ross E Staudt, Robert D Carlson, and Adam E. Snook

PDF

Age Moderates the Effect of Injury Severity on Functional Trajectories in Traumatic Brain Injury: A Study Using the NIDILRR Traumatic Brain Injury Model Systems National Dataset., Laraine Winter, Janell L Mensinger, Helene J Moriarty, Keith M Robinson, Michelle McKay, and Benjamin E Leiby

Manuscripts from 2021

PDF

A cancer ubiquitome landscape identifies metabolic reprogramming as target of Parkin tumor suppression, Ekta Agarwal, Aaron R Goldman, Hsin-Yao Tang, Andrew V Kossenkov, Jagadish C Ghosh, Lucia Languino, Valentina Vaira, David W Speicher, and Dario C Altieri

PDF

THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Catalytic receptors, Stephen PH Alexander, Doriano Fabbro, Eamonn Kelly, Alistair Mathie, John A Peters, Emma L Veale, Jane F Armstrong, Elena Faccenda, Simon D Harding, Adam J Pawson, Christopher Southan, Jamie A Davies, Annie Beuve, Peter Brouckaert, Clare Bryant, John C Burnett, Richard W Farndale, Andreas Friebe, John Garthwaite, Adrian J Hobbs, Gavin E Jarvis, Michaela Kuhn, David MacEwan, Tom P Monie, Andreas Papapetropoulos, Lincoln R Potter, Harald H H W Schmidt, Csaba Szabo, and Scott A Waldman

PDF

Choline-Sigma-1R as an Additional Mechanism for Potentiation of Orexin by Cocaine, Jeffrey Barr, Pingwei Zhao, G Cristina Brailoiu, and Eugen Brailoiu

PDF

Seeking Similarities Rather Than Differences With Adults to Aid in Therapeutic Advancement for Children., Mara L. Becker and Walter K. Kraft

PDF

Longitudinal evaluation of azithromycin and cytokine concentrations in amniotic fluid following one-time oral dosing in pregnancy., Rupsa C. Boelig, Edwin Lam, Ankit Rochani, Gagan Kaushal, Amanda Roman, and Walter K. Kraft

PDF

Emerging targets for the diagnosis of Parkinson's disease: examination of systemic biomarkers., Lara Cheslow, Adam E. Snook, and Scott A. Waldman

PDF

Printing the Pathway Forward in Bone Metastatic Cancer Research: Applications of 3D Engineered Models and Bioprinted Scaffolds to Recapitulate the Bone-Tumor Niche., Anne M. Hughes, Alexus D. Kolb, Alison B. Shupp, Kristy M. Shine, and Karen M. Bussard

PDF

Retinoids as Chemo-Preventive and Molecular-Targeted Anti-Cancer Therapies., Victoria O. Hunsu, Caroline O.B. Facey, Jeremy Z. Fields, and Bruce M. Boman

PDF

Association of Dietary Total Antioxidant Capacity with Bone Mass and Osteoporosis Risk in Korean Women: Analysis of the Korea National Health and Nutrition Examination Survey 2008-2011, Donghyun Kim, Anna Han, and Yongsoon Park

PDF

'Educated' Osteoblasts Reduce Osteoclastogenesis in a Bone-Tumor Mimetic Microenvironment., Alexus D. Kolb, Jinlu Dai, Evan T. Keller, and Karen M. Bussard

PDF

A Randomized Trial to Improve Adherence to Follow-up Eye Examinations Among People With Glaucoma, Benjamin E Leiby, Sarah E. Hegarty, Tingting Zhan, Jonathan S Myers, L Jay Katz, Julia A Haller, Michael Waisbourd, Christine Burns, Meskerem Divers, Jeanne Molineaux, Jeffrey Henderer, Charles Brodowski, and Lisa A Hark

PDF

The Quandary of DNA-Based Treatment Assessment in De Novo Metastatic Prostate Cancer in the Era of Precision Oncology., Sigve Nakken, Wolfgang Lilleby, Marta D. Switlyk, Karen E Knudsen, Oscar Lilleby, Sen Zhao, Fatemeh Kaveh, Per O. Ekstrøm, Alfonso Urbanucci, and Eivind Hovig

PDF

IFIT3 (interferon induced protein with tetratricopeptide repeats 3) modulates STAT1 expression in small extracellular vesicles., Nicole M Naranjo, Israa Salem, Maisha A Harris, and Lucia R Languino

PDF

Correlations between Coffee Consumption and Metabolic Phenotypes, Plasma Folate, and Vitamin B12: NHANES 2003 to 2006., Pratibha V Nerurkar, Krupa Gandhi, and John J Chen

PDF

Level of utilization and provider-related barriers to the use of hydroxyurea in the treatment of sickle cell disease patients in Jos, North-Central Nigeria, Akinyemi O.D. Ofakunrin, Edache S. Okpe, Tolulope O. Afolaranmi, Rasaq Olaosebikan, Patience U. Kanhu, Kehinde Adekola, Nantok Dami, and Atiene S. Sagay

PDF

Redefining cancer of unknown primary: Is precision medicine really shifting the paradigm?, Timothée Olivier, Eugenio Fernandez, Intidhar Labidi-Galy, Pierre-Yves Dietrich, Veronica Rodriguez-Bravo, Giulia Baciarello, Karim Fizazi, and Anna Patrikidou

PDF

MYC regulates ribosome biogenesis and mitochondrial gene expression programs through its interaction with host cell factor-1., Tessa M. Popay, Jing Wang, Clare M. Adams, Gregory Caleb Howard, Simona G. Codreanu, Stacy D. Sherrod, John A. McLean, Lance R. Thomas, Shelly L. Lorey, Yuichi J. Machida, April M. Weissmiller, Christine M. Eischen, Qi Liu, and William P. Tansey

PDF

Targeting the cdk6 dependence of ph+ acute lymphoblastic leukemia, Patrizia Porazzi, Marco De Dominici, Joseph Salvino, and Bruno Calabretta

PDF

Differential expression of αVβ3 and αVβ6 integrins in prostate cancer progression, Fabio Quaglia, Shiv Ram Krishn, Yanqing Wang, David W Goodrich, Peter McCue, Andrew Kossenkov, Amy C Mandigo, Karen Knudsen, Paul H Weinreb, Eva Corey, William Kevin Kelly, and Lucia R Languino

PDF

SOX10 requirement for melanoma tumor growth is due, in part, to immune-mediated effects, Sheera Rosenbaum, Manoela Tiago, Signe Caksa, Claudia Capparelli, Timothy J. Purwin, Gaurav Kumar, McKenna Glasheen, Danielle Pomante, Daniel Kotas, I Chervoneva, and A E Aplin

PDF

The circadian cryptochrome, CRY1, is a pro-tumorigenic factor that rhythmically modulates DNA repair., Ayesha A Shafi, Chris M McNair, Jennifer J McCann, Mohammed Alshalalfa, Anton Shostak, Tesa M Severson, Yanyun Zhu, Andre Bergman, Nicolas Gordon, Amy C Mandigo, Saswati N Chand, Peter Gallagher, Emanuela Dylgjeri, Talya S Laufer, Irina A Vasilevskaya, Matthew J Schiewer, Michael Brunner, Felix Y Feng, Wilbert Zwart, and Karen E Knudsen

PDF

Review article: diagnosis, management and patient perspectives of the spectrum of constipation disorders., Amol Sharma, Satish S C Rao, Kimberly Kearns, Kimberly D Orleck, and Scott A Waldman

PDF

The Role of miRNAs, miRNA Clusters, and isomiRs in Development of Cancer Stem Cell Populations in Colorectal Cancer., Victoria A Stark, Caroline O B Facey, Vignesh Viswanathan, and Bruce M Boman

PDF

Targeted Treatment of Head and Neck (Pre)Cancer: Preclinical Target Identification and Development of Novel Therapeutic Applications, Anne van Harten and Ruud H. Brakenhoff

PDF

Point-of-Care Lung Ultrasound for COVID-19: Findings and Prognostic Implications From 105 Consecutive Patients, Kosuke Yasukawa, Taro Minami, David R Boulware, Ayako Shimada, and Ernest A Fischer

PDF

miRcorrNet: machine learning-based integration of miRNA and mRNA expression profiles, combined with feature grouping and ranking., Malik Yousef, Gokhan Goy, Ramkrishna Mitra, Christine M. Eischen, Amhar Jabeer, and Burcu Bakir-Gungor

Manuscripts from 2020

PDF

Unexpected cell type-dependent effects of autophagy on polyglutamine aggregation revealed by natural genetic variation in C. elegans., J Alexander-Floyd, S Haroon, M Ying, A A Entezari, C Jaeger, M Vermulst, and T Gidalevitz

PDF

APC-β-catenin-TCF signaling silences the intestinal guanylin-GUCY2C tumor suppressor axis., Erik S Blomain, Jeffrey A Rappaport, Amanda M Pattison, Babar Bashir, Ellen Caparosa, Jonathan Stem, Adam E Snook, and Scott A Waldman

PDF

Autocatalytic Tissue Polymerization Reaction Mechanism in Colorectal Cancer Development and Growth., Bruce M Boman, Arthur Guetter, Ryan M Boman, and Olaf A Runquist

PDF

The membrane-associated form of cyclin D1 enhances cellular invasion, Ke Chen, Xuanmao Jiao, Anthony Ashton, Agnese Di Rocco, Timothy G Pestell, Yunguang Sun, Jun Zhao, Mathew C Casimiro, Zhiping Li, Michael P Lisanti, Peter McCue, Duanwen Shen, Samuel Achilefu, Hallgeir Rui, and Richard G Pestell

PDF

Endogenous Cyclin D1 Promotes the Rate of Onset and Magnitude of Mitogenic Signaling via Akt1 Ser473 Phosphorylation., Ke Chen, Xuanmao Jiao, Agnese Di Rocco, Duanwen Shen, Shaohua Xu, Adam Ertel, Zuoren Yu, Gabriele Di Sante, Min Wang, Zhiping Li, Timothy G Pestell, Mathew C Casimiro, Emmanuel Skordalakes, Samuel Achilefu, and Richard G Pestell

PDF

Development of an abbreviated symptom score for the neonatal abstinence syndrome., I. Chervoneva, S. C. Adeniyi-Jones, F. Blanco, and W. K. Kraft

PDF

Chimeric Ad5.F35 vector evades anti-adenovirus serotype 5 neutralization opposing GUCY2C-targeted antitumor immunity, John C. Flickinger, Jagmohan Singh, Robert D Carlson, Elinor Leong, Trevor R. Baybutt, Joshua Barton, Ellen M. Caparosa, Amanda M. Pattison, Jeff A. Rappaport, Jamin Roh, Tingting Zhan, Babar Bashir, Scott A Waldman, and Adam E. Snook

PDF

Epidemiology of COVID-19 and Predictors of Outcome in Nigeria: A Single-Center Study., Olayinka Rasheed Ibrahim, Bello Muhammed Suleiman, Suleiman Bello Abdullahi, Taofeek Oloyede, Abdallah Sanda, Maruf Sanusi Gbadamosi, Bashir Olajide Yusuf, Rabilu Yandoma Iliyasu, Lawal Magaji Ibrahim, Adamu Danladi Dawud, Sulaiman Saidu Bashir, Nwawueze Efam Okonta, Wasinda Francis Umar, Abiodun Gbenga Tekobo, Muhammadu Sani Abubakar, Bashir Taiye Aminu, Shuaibu Onoruoyiza Ibrahim, Rasaq Olaosebikan, and Olugbenga Ayodeji Mokuolu

PDF

Mobilizing Toxins for Cancer Treatment: Historical Perspectives and Current Strategies., Jessica Kopenhaver, Robert D Carlson, and Adam E Snook

PDF

Artificial Intelligence-Powered Search Tools and Resources in the Fight Against COVID-19., Larry J Kricka, Sergei Polevikov, Jason Y Park, Paolo Fortina, Sergio Bernardini, Daniel Satchkov, Valentin Kolesov, and Maxim Grishkov

PDF

The αvβ6 integrin in cancer cell-derived small extracellular vesicles enhances angiogenesis., Shiv Ram Krishn, Israa Salem, Fabio Quaglia, Nicole M Naranjo, Ekta Agarwal, Qin Liu, Srawasti Sarker, Jessica Kopenhaver, Peter A McCue, Paul H Weinreb, Shelia M Violette, Dario C Altieri, and Lucia R Languino

PDF

iSeqQC: a tool for expression-based quality control in RNA sequencing., Gaurav Kumar, Adam Ertel, George Feldman, Joan Kupper, and Paolo Fortina

PDF

Vancomycin in peritoneal dialysis: Clinical pharmacology considerations in therapy., Edwin Lam, Yi Ting Kayla Lien, Walter K. Kraft, Beth Piraino, Valvanera Vozmediano, Stephan Schmidt, and Jingjing Zhang

PDF

Twice-Daily Doravirine Overcomes the Interaction Effect from Once-Weekly Rifapentine and Isoniazid in Healthy Volunteers., Edwin Lam, Joseph Schaefer, Richard Zheng, Tingting Zhan, and Walter K. Kraft

PDF

Simulation-based mastery learning compared to standard education for discussing diagnostic uncertainty with patients in the emergency department: a randomized controlled trial., Danielle M. McCarthy, Rhea E. Powell, Kenzie A. Cameron, David H. Salzman, Dimitrios Papanagnou, Amanda Doty, Benjamin E. Leiby, Katherine Piserchia, Matthew R. Klein, Xiao C. Zhang, William C. McGaghie, and Kristin L. Rising

PDF

Pan-cancer analysis reveals cooperativity of both strands of microRNA that regulate tumorigenesis and patient survival, Ramkrishna Mitra, Clare M. Adams, Wei Jiang, Evan J. Greenawalt, and Christine M. Eischen

PDF

Functional Blockade of E-Selectin in Tumor-Associated Vessels Enhances Anti-Tumor Effect of Doxorubicin in Breast Cancer, Yoshihiro Morita, Macall Leslie, Hiroyasu Kameyama, Ganesh L R Lokesh, Norihisa Ichimura, Rachel Davis, Natalie Hills, Nafis Hasan, Roy Zhang, Yuji Kondo, David G Gorenstein, David E Volk, Inna Chervoneva, Hallgeir Rui, and Takemi Tanaka

PDF

Hitting the Bullseye: Are extracellular vesicles on target?, Nicole Noren Hooten, María Yáñez-Mó, Rachel M. DeRita, Ashley Russell, Peter Quesenberry, Bharat Ramratnam, Paul D Robbins, Dolores Di Vizio, Sicheng Wen, Kenneth W Witwer, and Lucia R Languino

PDF

Fatal case of newborn Lassa fever virus infection mimicking late onset neonatal sepsis: a case report from northern Nigeria, Taofik Oluwaseun Ogunkunle, Surajudeen Oyeleke Bello, Chinwe Immaculata Anderson, Rashida Musa, Rasaq Olaosebikan, and Abdulazeez Imam

PDF

MicroRNA and transcription factor co-regulatory networks and subtype classification of seminoma and non-seminoma in testicular germ cell tumors, Guimin Qin, Saurav Mallik, Ramkrishna Mitra, Aimin Li, Peilin Jia, Christine M. Eischen, and Zhongming Zhao

PDF

MicroRNA and transcription factor co-regulatory networks and subtype classification of seminoma and non-seminoma in testicular germ cell tumors., Guimin Qin, Saurav Mallik, Ramkrishna Mitra, Aimin Li, Peilin Jia, Christine M. Eischen, and Zhongming Zhao

PDF

FOXD3 Regulates VISTA Expression in Melanoma., Sheera R. Rosenbaum, Meghan Knecht, Mehri Mollaee, Zhijiu Zhong, Dan A. Erkes, Peter A. McCue, Chervoneva, Adam C. Berger, Jennifer A. Lo, David E. Fisher, Jeffrey E. Gershenwald, Michael A. Davies, Timothy J. Purwin, and Andrew E. Aplin

PDF

Profiling the circulating mRNA transcriptome in human liver disease, Aejaz Sayeed, Brielle E Dalvano, David E Kaplan, Usha Viswanathan, John Kulp, Alhaji H Janneh, Lu-Yu Hwang, Adam Ertel, Cataldo Doria, and Timothy Block

PDF

MicroRNA Expression Profiling of Normal and Malignant Human Colonic Stem Cells Identifies, Vignesh Viswanathan, Lynn Opdenaker, Shirin Modarai, Jeremy Z Fields, Gregory Gonye, and Bruce M Boman

Manuscripts from 2019

PDF

Myc-mediated transcriptional regulation of the mitochondrial chaperone TRAP1 controls primary and metastatic tumor growth., Ekta Agarwal, Brian J. Altman, Jae Ho Seo, Jagadish C. Ghosh, Andrew V Kossenkov, Hsin-Yao Tang, Shiv Ram Krishn, Lucia R. Languino, Dmitry I. Gabrilovich, David W. Speicher, Chi V. Dang, and Dario C. Altieri

PDF

No meaningful drug interactions with doravirine, lamivudine and tenofovir disoproxil fumarate co-administration., Matt S. Anderson, Jocelyn Gilmartin, Li Fan, Ka Lai Yee, Walter K. Kraft, Ilias Triantafyllou, Christina Reitmann, Ying Guo, Rachael Liu, and Marian Iwamoto

PDF

Silencing the GUCA2A-GUCY2C tumor suppressor axis in CIN, serrated, and MSI colorectal neoplasia., Babar Bashir, Dante J. Merlino, Jeff A. Rappaport, Esteban Gnass, Juan P. Palazzo, Ying Feng, Eric R R. Fearon, Adam E. Snook, and Scott A. Waldman

PDF

Advances in Chimeric Antigen Receptor T-Cell Therapies for Solid Tumors., Trevor R. Baybutt, John C. Flickinger, Ellen M. Caparosa, and Adam E. Snook

PDF

Tumor-Derived Extracellular Vesicles Require β1 Integrins to Promote Anchorage-Independent Growth., Rachel M. DeRita, Aejaz Sayeed, Vaughn Garcia, Shiv Ram Krishn, Christopher D. Shields, Srawasti Sarker, Andrea Friedman, Peter McCue, Sudheer Kumar Molugu, Ulrich Rodeck, Adam P. Dicker, and Lucia R. Languino

PDF

Sighting acute myocardial infarction through platelet gene expression., Giuliana Gobbi, Cecilia Carubbi, Guidantonio Malagoli Tagliazucchi, Elena Masselli, Prisco Mirandola, Filippo Pigazzani, Antonio Crocamo, Maria Francesca Notarangelo, Sergio Suma, Elvezia Paraboschi, Giuseppe Maglietta, Srikanth Nagalla, Giulia Pozzi, Daniela Galli, Mauro Vaccarezza, Paolo Fortina, Sankar Addya, Adam Ertel, Paul Bray, Stefano Duga, Carlo Berzuini, Marco Vitale, and Diego Ardissino

PDF

CADM1 is a TWIST1-regulated suppressor of invasion and survival., Edward J. Hartsough, Michele B. Weiss, Shea A. Heilman, Timothy J. Purwin, Curtis H Kugel, Sheera R. Rosenbaum, Dan A. Erkes, Manoela Tiago, Kim Hookim, Inna Chervoneva, and Andrew E. Aplin

PDF

Non-Thermal Plasma-Induced Immunogenic Cell Death in Cancer: A Topical Review., Marian Khalili, Lynsey Daniels, Abraham Lin, Fred C. Krebs, Adam E. Snook, Sander Bekeschus, Wilbur B. Bowne, and Vandana Miller

PDF

The Bone Extracellular Matrix as an Ideal Milieu for Cancer Cell Metastases., Alexus D. Kolb and Karen M. Bussard

PDF

Osteoblasts are "educated" by crosstalk with metastatic breast cancer cells in the bone tumor microenvironment., Alexus D. Kolb, Alison B. Shupp, Dimpi Mukhopadhyay, Frank C. Marini, and Karen M. Bussard