Document Type

Article

Publication Date

1-1-2020

Comments

This is the final published version the article from Journal of Extracellular Vesicles, 2020, Vol. 9, 1763594

The published version of the article can be found at https://doi.org/10.1080/20013078.2020.1763594

Copyright Krishn et.al.

Abstract

Prostate cancer (PrCa) cells crosstalk with the tumour microenvironment by releasing small extracellular vesicles (sEVs). sEVs, as well as large extracellular vesicles (LEVs), isolated via iodixanol density gradients from PrCa cell culture media, express the epithelial-specific αvβ6 integrin, which is known to be induced in cancer. In this study, we show sEV-mediated protein transfer of αvβ6 integrin to microvascular endothelial cells (human microvascular endothelial cells 1 - HMEC1) and demonstrate that

Creative Commons License

Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial 4.0 License

PubMed ID

32595914

Language

English

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