Submissions from 2024
Identifying Targetable Vulnerabilities to Circumvent or Overcome Venetoclax Resistance in Diffuse Large B-Cell Lymphoma, Clare M. Adams, Amanda McBride, Peter Michener, Irina Shkundina, Ramkrishna Mitra, Hyun Hwan An, Pierluigi Porcu, and Christine M. Eischen
CD8α Structural Domains Enhance GUCY2C CAR-T Cell Efficacy, Trevor R. Baybutt, Ariana A. Entezari, Adi Caspi, Ross E. Staudt, Robert D. Carlson, Scott A. Waldman, and Adam E. Snook
Role of Kindlin 2 in Prostate Cancer, Katarzyna Bialkowska, Lamyae El Khalki, Priyanka Rana, Wei Wang, Daniel Lindner, Yvonne Parker, Lucia Languino, Dario Altieri, Elzbieta Pluskota, Khalid Sossey-Alaoui, and Edward Plow
Travel-Time Disparities in Access to Proton Beam Therapy for Cancer Treatment, Todd Burus, Alexander VanHelene, Michael Rooney, Krystle Lang Kuhs, W. Jay Christian, Christopher McNair, Sanjay Mishra, Arnold Paulino, Grace Smith, Steven Frank, and Jeremy Warner
Biomarkers for Managing Neurodegenerative Diseases, Lara Cheslow, Adam E. Snook, and Scott A. Waldman
Prevalence and Prognostication of CD5+ Mature T-Cell Lymphomas, Omar Elghawy, Miao Cao, Jason Xu, Daniel J. Landsburg, Jakub Svoboda, Sunita D. Nasta, Elise A. Chong, Stephen J. Schuster, Colin J. Thomas, Jordan S. Carter, Montreh Tavakkoli, Marco Ruella, and Stefan K. Barta
CYP26A1 Links WNT and Retinoic Acid Signaling: A Target to Differentiate ALDH+ Stem Cells in APC-Mutant CRC, Caroline O.B. Facey, Victoria O. Hunsu, Chi Zhang, Brian Osmond, Lynn M. Opdenaker, and Bruce M. Boman
BP1003 Decreases STAT3 Expression and Its Pro-Tumorigenic Functions in Solid Tumors and the Tumor Microenvironment, Maria Gagliardi, Rhonda Kean, Bingbing Dai, Jithesh Augustine, Michael Roberts, Jason Fleming, D. Craig Hooper, and Ana Ashizawa
A Cyclin D1 Intrinsically Disordered Domain Accesses Modified Histone Motifs to Govern Gene Transcription, Xuanmao Jiao, Gabriele Di Sante, Mathew Casimiro, Agnes Tantos, Anthony Ashton, Zhiping Li, Yen Quach, Dharmendra Bhargava, Agnese Di Rocco, Claudia Pupo, Marco Crosariol, Tamas Lazar, Peter Tompa, Chenguang Wang, Zuoren Yu, Zhao Zhang, Kawthar Aldaaysi, Ratna Vadlamudi, Monica Mann, Emmanuel Skordalakes, Andrew Kossenkov, Yanming Du, and Richard Pestell
A Representative Clinical Course of Progression, with Molecular Insights, of Hormone Receptor-Positive, HER2-Negative Bone Metastatic Breast Cancer, Elizabeth Magno and Karen M. Bussard
Abstinence Scoring Algorithms for Treatment of Neonatal Opioid Withdrawal Syndrome (NOWS), Brenton A. Maisel, Susan C. Adeniyi-Jones, Eric Selvage, Samuel Ng, Walter K. Kraft, and Inna Chervoneva
STAT5 Induces Androgen Receptor (AR) Gene Transcription in Prostate Cancer and Offers a Druggable Pathway to Target AR Signaling, Cristina Maranto, Lavannya Sabharwal, Vindhya Udhane, Samuel P. Pitzen, Braedan McCluskey, Songyan Qi, Christine O'Connor, Savita Devi, Scott Johnson, Kenneth Jacobsohn, Anjishnu Banerjee, Kenneth A. Iczkowski, Liang Wang, Scott M. Dehm, and Marja T. Nevalainen
Neuroendocrine Gene Subsets Are Uniquely Dysregulated in Prostate Adenocarcinoma, Nicole M. Naranjo, Anne Kennedy, Anna Testa, Cecilia E. Verrillo, Adrian D. Altieri, Rhonda Kean, D. Craig Hooper, Jindan Yu, Jonathan Zhao, Oliver Abinader, Maxwell W. Pickles, Adam Hawkins, William Kevin Kelly, Ramkrishna Mitra, and Lucia R. Languino
Impact of an Online Decision Support tool for Ductal Carcinoma In Situ (DCIS) Using a Pre-Post Design (AFT-25), Elissa Ozanne, Kellyn Maves, Angela Tramontano, Thomas Lynch, Alastair Thompson, Ann Partridge, Elizabeth Frank, Deborah Collyar, Desiree Basila, Donna Pinto, Terry Hyslop, Marc Ryser, Shoshana Rosenberg, E. Shelley Hwang, and Rinaa Punglia
Stanniocalcin 2 Governs Cancer Cell Adaptation to Nutrient Insufficiency Through Alleviation of Oxidative Stress, Shuo Qie, Haijuan Xiong, Yaqi Liu, Chenhui Yan, Yalei Wang, Lifeng Tian, Chenguang Wang, and Nianli Sang
Evaluating Attitudes on Health-Seeking Behavior Among a Network of People Who Inject Drugs, Ayako Shimada, Ashley Buchanan, Natallia Katenka, Benjamin Skov, Gabrielle Lemire, Stephen Kogut, and Samuel Friedman
The Janus Kinase 1 is Critical for Pancreatic Cancer Initiation and Progression, Hridaya Shrestha, Patrick Rädler, Rayane Dennaoui, Madison Wicker, Nirakar Rajbhandari, Yunguang Sun, Amy Peck, Kerry Vistisen, Aleata Triplett, Rafic Beydoun, Esta Sterneck, Dieter Saur, Hallgeir Rui, and Kay-Uwe Wagner
Expression of the αVβ3 Integrin Affects Prostate Cancer sEV Cargo and density and promotes sEV Pro-Tumorigenic Activity In Vivo Through a GPI-Anchored Receptor, NgR2, Cecilia Verrillo, Fabio Quaglia, Christopher Shields, Stephen Lin, Andrew Kossenkov, Hsin-Yao Tang, David Speicher, Nicole Naranjo, Anna Testa, William Kelly, Qin Liu, Benjamin Leiby, Luca Musante, Khalid Sossey-Alaoui, Navneet Dogra, Tzu-Yi Chen, Dario Altieri, and Lucia Languino
Intracellular Islatravir-Triphosphate Half-Life Supports Extended Dosing Intervals, Xiaowei Zang, Wendy Ankrom, Walter K. Kraft, Ryan Vargo, S Aubrey Stoch, Marian Iwamoto, and Randolph P Matthews
Noninvasive Multi-Cancer Detection Using Blood-Based Cell-Free MicroRNAs, Jason Zhang, Hallgeir Rui, and Hai Hu
Submissions from 2023
The Concise Guide to PHARMACOLOGY 2023/24: Catalytic Receptors, Stephen P.H. Alexander, Doriano Fabbro, Eamonn Kelly, Alistair A. Mathie, John A. Peters, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Jamie A. Davies, Annie Beuve, Peter Brouckaert, Clare Bryant, John C. Burnett, Richard W. Farndale, Andreas Friebe, John Garthwaite, Adrian J. Hobbs, Gavin E. Jarvis, Doris Koesling, Michaela Kuhn, David MacEwan, Tom P. Monie, Lincoln R. Potter, Michael Russwurm, Harald H.H.W. Schmidt, Johannes-Peter Stasch, and Scott A. Waldman
Kinome Profiling Identifies MARK3 and STK10 as Potential Therapeutic Targets in Uveal Melanoma, Usman Baqai, Alison M. Kurimchak, Isabella Trachtenberg, Timothy J. Purwin, Jelan I. Haj, Anna Han, Kristine Luo, Nikole Fandino Pachon, Angela Jeon, Vivian Chua, Michael A. Davies, J Silvio Gutkind, Jeffrey L. Benovic, James S. Duncan, and Andrew E. Aplin
Enteroendocrine Cell Regulation of the Gut-Brain Axis, Joshua Barton, Annie Londregan, Tyler Alexander, Ariana Entezari, Manuel Covarrubias, and Scott Waldman
Intestinal Neuropod Cell GUCY2C Regulates Visceral Pain, Joshua R. Barton, Annie K. Londregran, Tyler D. Alexander, Ariana A. Entezari, Shely Bar-Ad, Lan Cheng, Angelo C. Lepore, Adam E. Snook, Manuel Covarrubias, and Scott A. Waldman
27-hydroxycholesterol and DNA Damage Repair: Implication in Prostate Cancer, Gloria Cecilia Galvan, Nadine Friedrich, Sanjay Das, James Daniels, Sara Pollan, Shweta Dambal, Ryusuke Suzuki, Sergio Sanders, Sungyong You, Hisashi Tanaka, Yeon-Joo Lee, Wei Yuan, Johann de Bono, Irina Vasilevskaya, Karen Knudsen, Michael Freeman, and Stephen Freedland
Co-Targeting FASN and mTOR Suppresses Uveal Melanoma Growth, Anna Han, Dzmitry Mukha, Vivian Chua, Timothy J. Purwin, Manoela Tiago, Bhavik Modasia, Usman Baqai, Jenna Aumiller, Nelisa Bechtel, Emily Hunter, Meggie Danielson, Mizue Terai, Philip B. Wedegaertner, Takami Sato, Solange Landreville, Michael A. Davies, Stefan Kurtenbach, William J. Harbour, Zachary T. Schug, and Andrew E. Aplin
Needle Biopsy Accelerates Pro-metastatic Changes and Systemic Dissemination in Breast Cancer: Implications for Mortality by Surgery Delay, Hiroyasu Kameyama, Priya Dondapati, Reese Simmons, Macall Leslie, John Langenheim, Yunguang Sun, Misung Yi, Aubrey Rottschaefer, Rashmi Pathak, Shreya Nuguri, Kar-Ming Fung, Shirng-Wern Tsaih, Inna Chervoneva, Hallgeir Rui, and Takemi Tanaka
A Review of IsomiRs in Colorectal Cancer, Molly A. Lausten and Bruce M. Boman
Desmoglein-2 as a Cancer Modulator: Friend or Foe?, Kay Myo Min, Charlie Ffrench, Barbara McClure, Michael Ortiz, Emma Dorward, Michael Samuel, Lisa Ebert, Mỹ Mahoney, and Claudine Bonder
Comparison of Bacterial Culture With Biofire® Filmarray® Multiplex PCR Screening of Archived Cerebrospinal Fluid Specimens From Children With Suspected Bacterial Meningitis in Nigeria, S Obaro, F Hassan-Hanga, N Medugu, Rasaq Olaosebikan, G Olanipekun, B Jibir, S Gambo, Theresa Ajose, Carissa Duru, B Ebruke, and H D Davies
Gene Signature Reveals Decreased SOX10-Dependent Transcripts in Malignant Cells From Immune Checkpoint Inhibitor-Resistant Cutaneous Melanomas, Timothy J. Purwin, Signe Caksa, Ahmet Sacan, Claudia Capparelli, and Andrew E. Aplin
Targeting the αvβ3/NGR2 Pathway in Neuroendocrine Prostate Cancer, Anna Testa, Fabio Quaglia, Nicole M. Naranjo, Cecilia E. Verrillo, Christopher D. Shields, Stephen Lin, Maxwell W. Pickles, Drini F. Hamza, Tami Von Schalscha, David A. Cheresh, Benjamin E Leiby, Qin Liu, Jianyi Ding, William K. Kelly, D. Craig Hooper, Eva Corey, Edward F. Plow, Dario C. Altieri, and Lucia R. Languino
Parkin Ubiquitination of Kindlin-2 Enables Mitochondria-Associated Metastasis Suppression, Minjeong Yeon, Irene Bertolini, Ekta Agarwal, Jagadish C Ghosh, Hsin-Yao Tang, David W. Speicher, Frederick Keeney, Khalid Sossey-Alaoui, Elzbieta Pluskota, Katarzyna Bialkowska, Edward F. Plow, Lucia R. Languino, Emmanuel Skordalakes, M Cecilia Caino, and Dario C. Altieri
Selection of Optimal Quantile Protein Biomarkers Based on Cell-Level Immunohistochemistry Data, Misung Yi, Tingting Zhan, Amy R. Peck, Jeffrey A. Hooke, Albert J. Kovatich, Craig D. Shriver, Hai Hu, Yunguang Sun, Hallgeir Rui, and Inna Chervoneva
Manuscripts from 2022
Circulating Messenger RNA Variants as a Potential Biomarker for Surveillance of Hepatocellular Carcinoma, Timothy Block, Daniel Zezulinski, David E. Kaplan, Jingqiao Lu, Samantha Zanine, Tingting Zhan, Cataldo Doria, and Aejaz Sayeed
A Genome-Wide Screen Identifies PDPK1 as a Target to Enhance the Efficacy of MEK1/2 Inhibitors, Weijia Cai, Nicole A. Wilski, Timothy J. Purwin, Megane Vernon, Manoela Tiago, and Andrew E. Aplin
The future of targeted kinase inhibitors in melanoma, Signe Caksa, Usman Baqai, and A E Aplin
Targeting SOX10-deficient cells to reduce the dormant-invasive phenotype state in melanoma, Claudia Capparelli; Timothy J. Purwin; McKenna Glasheen; Signe Caksa; Manoela Tiago; Nicole A. Wilski; Danielle Pomante; Sheera Rosenbaum; Mai Q Nguyen; Weijia Cai; Janusz Franco-Barraza; R. Zheng, MD; Gaurav Kumar; I Chervoneva; Ayako Shimada; Vito W Rebecca; Adam E. Snook; Kim Hookim; Xiaowei Xu; Edna Cukierman; Meenhard Herlyn; and A E Aplin
Guanylyl cyclase C as a Diagnostic and Therapeutic Target in Colorectal Cancer, Adi Caspi, Ariana A. Entezari, Madison Crutcher, Adam E. Snook, and Scott A. Waldman
Pharmacologic Ascorbic Acid as Early Therapy for Hospitalized Patients with COVID-19: A Randomized Clinical Trial, Dagan Coppock, Pierre-Christian Violet, Gustavo Vasquez, Katherine Belden, Michael Foster, Bret Mullin, Devon Magee, Isabelle Mikell, Lokesh Shah, Victoria Powers, Brian Curcio, Daniel A. Monti, and Mark Levine
DNA-PKcs: A Targetable Protumorigenic Protein Kinase., Emanuela Dylgjeri and Karen E Knudsen
T-Cell Responses to Immunodominant Listeria Epitopes Limit Vaccine-Directed Responses to the Colorectal Cancer Antigen, Guanylyl Cyclase C, John C. Flickinger, Jagmohan Singh, Yanki Yarman, Robert D Carlson, Joshua Barton, Scott A Waldman, and Adam E. Snook
Ghost mitochondria drive metastasis through adaptive GCN2/Akt therapeutic vulnerability, Jagadish C Ghosh, Michela Perego, Ekta Agarwal, Irene Bertolini, Yuan Wang, Aaron R Goldman, Hsin-Yao Tang, Andrew V Kossenkov, Catherine J Libby, Lucia R Languino, Edward F Plow, Annamaria Morotti, Luisa Ottobrini, Marco Locatelli, David W Speicher, M Cecilia Caino, Joel Cassel, Joseph M Salvino, Marie E Robert, Valentina Vaira, and Dario C Altieri
Stabilized COre Gene and Pathway Election Uncovers Pan-Cancer Shared Pathways and a Cancer-Specific Driver, Pathum Kossinna, Weijia Cai, Xuewen Lu, Carrie S Shemanko, and Qingrun Zhang
Functional Assessment of Missense Variants in the ABCC6 Gene Implicated in Pseudoxanthoma Elasticum, a Heritable Ectopic Mineralization Disorder., Luke Kowal, Jianhe Huang, Hongbin Luo, Jagmohan Singh, Adam E Snook, Jouni Uitto, and Qiaoli Li
Small extracellular vesicle-mediated ITGB6 siRNA delivery downregulates the αVβ6 integrin and inhibits adhesion and migration of recipient prostate cancer cells, Shiv Ram Krishn, Vaughn Garcia, Nicole M Naranjo, Fabio Quaglia, Christopher D Shields, Maisha A Harris, Andrew V Kossenkov, Qin Liu, Eva Corey, Dario C Altieri, and Lucia R Languino
Lysine Methyltransferase NSD1 and Cancers: Any Role in Melanoma?, Imène Krossa, Thomas Strub, Andrew E Aplin, Robert Ballotti, and Corine Bertolotto
CTpathway: A Crosstalk-Based Pathway Enrichment Analysis Method for Cancer Research, Haizhou Liu, Mengqin Yuan, Ramkrishna Mitra, Xu Zhou, Min Long, Wanyue Lei, Shunheng Zhou, Yu-E Huang, Fei Hou, Christine M. Eischen, and Wei Jiang
Spatial Metrics of Interaction between CD163-Positive Macrophages and Cancer Cells and Progression-Free Survival in Chemo-Treated Breast Cancer, Brenton Maisel, Misung Yi, Amy R Peck, Yunguang Sun, Jeffrey A Hooke, Albert J Kovatich, Craig D Shriver, Hai Hu, Marja T Nevalainen, Takemi Tanaka, Nicole L Simone, Li Lily Wang, Hallgeir Rui, and I Chervoneva
Novel Oncogenic Transcription Factor Cooperation in RB-Deficient Cancer, Amy C. Mandigo, Ayesha A Shafi, Jennifer J McCann, Wei Yuan, Talya Laufer, Denisa Bogdan, Lewis Gallagher, Emanuela Dylgjeri, Galina Semenova, Irina A Vasilevskaya, M J Schiewer, Chris M McNair, Johann S de Bono, and Karen E Knudsen
A Prospective Cohort Study of the Clinical Predictors of Bacteremia in Under-Five Children With Acute Undifferentiated Fever Attending a Secondary Health Facility in Northwestern Nigeria, Taofik Oluwaseun Ogunkunle, Timothy Olanrewaju Adedoyin, Samuel Kolade Ernest, Fatimah Hassan-Hanga, Abdulazeez Imam, Rasaq Olaosebikan, and Stephen K Obaro
HOXA9 Overexpression Contributes to Stem Cell Overpopulation That Drives Development and Growth of Colorectal Cancer, Brian Osmond, Caroline O.B. Facey, Chi Zhang, and Bruce M. Boman
Ondansetron to Reduce Neonatal Opioid Withdrawal Severity: A Randomized Clinical Trial, Gary Peltz, Lauren M. Jansson, Susan Adeniyi-Jones, Carol Cohane, David Drover, Steven Shafer, Meiyue Wang, Manhong Wu, Balaji Govindaswami, Priya Jegatheesan, Cynthia Argani, Salwa Kahn, and Walter K. Kraft
The NOGO Receptor NgR2, A Novel αVβ3 Integrin Effector, Induces Neuroendocrine Differentiation in Prostate Cancer, Fabio Quaglia, Shiv Ram Krishn, Khalid Sossey-Alaoui, Priyanka Shailendra Rana, Elzbieta Pluskota, Pyung Hun Park, Christopher D. Shields, Stephen Lin, Peter McCue, Andrew V. Kossenkov, Yanqing Wang, David W. Goodrich, Sheng-Yu Ku, Himisha Beltran, William K. Kelly, Eva Corey, Maja Klose, Christine Bandtlow, Qin Liu, Dario C. Altieri, Edward F. Plow, and Lucia R. Languino
RAS-mediated tumor stress adaptation and the targeting opportunities it presents, Alexandra Redding, A E Aplin, and Elda Grabocka
Development and Preclinical Investigation of Physically Cross-Linked and pH-Sensitive Polymeric Gels as Potential Vaginal Contraceptives, Ankit K. Rochani, Vivek Agrahari, Neelima Chandra, Onkar N Singh, Timothy J McCormick, Gustavo F Doncel, Meredith R Clark, and Gagan Kaushal
Targeting gastrointestinal cancers with chimeric antigen receptor (CAR)-T cell therapy, Ross E Staudt, Robert D Carlson, and Adam E. Snook
Age Moderates the Effect of Injury Severity on Functional Trajectories in Traumatic Brain Injury: A Study Using the NIDILRR Traumatic Brain Injury Model Systems National Dataset., Laraine Winter, Janell L Mensinger, Helene J Moriarty, Keith M Robinson, Michelle McKay, and Benjamin E Leiby
Manuscripts from 2021
A cancer ubiquitome landscape identifies metabolic reprogramming as target of Parkin tumor suppression, Ekta Agarwal, Aaron R Goldman, Hsin-Yao Tang, Andrew V Kossenkov, Jagadish C Ghosh, Lucia Languino, Valentina Vaira, David W Speicher, and Dario C Altieri
THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Catalytic receptors, Stephen PH Alexander, Doriano Fabbro, Eamonn Kelly, Alistair Mathie, John A Peters, Emma L Veale, Jane F Armstrong, Elena Faccenda, Simon D Harding, Adam J Pawson, Christopher Southan, Jamie A Davies, Annie Beuve, Peter Brouckaert, Clare Bryant, John C Burnett, Richard W Farndale, Andreas Friebe, John Garthwaite, Adrian J Hobbs, Gavin E Jarvis, Michaela Kuhn, David MacEwan, Tom P Monie, Andreas Papapetropoulos, Lincoln R Potter, Harald H H W Schmidt, Csaba Szabo, and Scott A Waldman
Choline-Sigma-1R as an Additional Mechanism for Potentiation of Orexin by Cocaine, Jeffrey Barr, Pingwei Zhao, G Cristina Brailoiu, and Eugen Brailoiu
Seeking Similarities Rather Than Differences With Adults to Aid in Therapeutic Advancement for Children., Mara L. Becker and Walter K. Kraft
Longitudinal evaluation of azithromycin and cytokine concentrations in amniotic fluid following one-time oral dosing in pregnancy., Rupsa C. Boelig, Edwin Lam, Ankit Rochani, Gagan Kaushal, Amanda Roman, and Walter K. Kraft
Emerging targets for the diagnosis of Parkinson's disease: examination of systemic biomarkers., Lara Cheslow, Adam E. Snook, and Scott A. Waldman
Printing the Pathway Forward in Bone Metastatic Cancer Research: Applications of 3D Engineered Models and Bioprinted Scaffolds to Recapitulate the Bone-Tumor Niche., Anne M. Hughes, Alexus D. Kolb, Alison B. Shupp, Kristy M. Shine, and Karen M. Bussard
Retinoids as Chemo-Preventive and Molecular-Targeted Anti-Cancer Therapies., Victoria O. Hunsu, Caroline O.B. Facey, Jeremy Z. Fields, and Bruce M. Boman
Association of Dietary Total Antioxidant Capacity with Bone Mass and Osteoporosis Risk in Korean Women: Analysis of the Korea National Health and Nutrition Examination Survey 2008-2011, Donghyun Kim, Anna Han, and Yongsoon Park
'Educated' Osteoblasts Reduce Osteoclastogenesis in a Bone-Tumor Mimetic Microenvironment., Alexus D. Kolb, Jinlu Dai, Evan T. Keller, and Karen M. Bussard
A Randomized Trial to Improve Adherence to Follow-up Eye Examinations Among People With Glaucoma, Benjamin E Leiby, Sarah E. Hegarty, Tingting Zhan, Jonathan S Myers, L Jay Katz, Julia A Haller, Michael Waisbourd, Christine Burns, Meskerem Divers, Jeanne Molineaux, Jeffrey Henderer, Charles Brodowski, and Lisa A Hark
The Quandary of DNA-Based Treatment Assessment in De Novo Metastatic Prostate Cancer in the Era of Precision Oncology., Sigve Nakken, Wolfgang Lilleby, Marta D. Switlyk, Karen E Knudsen, Oscar Lilleby, Sen Zhao, Fatemeh Kaveh, Per O. Ekstrøm, Alfonso Urbanucci, and Eivind Hovig
IFIT3 (interferon induced protein with tetratricopeptide repeats 3) modulates STAT1 expression in small extracellular vesicles., Nicole M Naranjo, Israa Salem, Maisha A Harris, and Lucia R Languino
Correlations between Coffee Consumption and Metabolic Phenotypes, Plasma Folate, and Vitamin B12: NHANES 2003 to 2006., Pratibha V Nerurkar, Krupa Gandhi, and John J Chen
Level of utilization and provider-related barriers to the use of hydroxyurea in the treatment of sickle cell disease patients in Jos, North-Central Nigeria, Akinyemi O.D. Ofakunrin, Edache S. Okpe, Tolulope O. Afolaranmi, Rasaq Olaosebikan, Patience U. Kanhu, Kehinde Adekola, Nantok Dami, and Atiene S. Sagay
Redefining cancer of unknown primary: Is precision medicine really shifting the paradigm?, Timothée Olivier, Eugenio Fernandez, Intidhar Labidi-Galy, Pierre-Yves Dietrich, Veronica Rodriguez-Bravo, Giulia Baciarello, Karim Fizazi, and Anna Patrikidou
MYC regulates ribosome biogenesis and mitochondrial gene expression programs through its interaction with host cell factor-1., Tessa M. Popay, Jing Wang, Clare M. Adams, Gregory Caleb Howard, Simona G. Codreanu, Stacy D. Sherrod, John A. McLean, Lance R. Thomas, Shelly L. Lorey, Yuichi J. Machida, April M. Weissmiller, Christine M. Eischen, Qi Liu, and William P. Tansey
Targeting the cdk6 dependence of ph+ acute lymphoblastic leukemia, Patrizia Porazzi, Marco De Dominici, Joseph Salvino, and Bruno Calabretta
Differential expression of αVβ3 and αVβ6 integrins in prostate cancer progression, Fabio Quaglia, Shiv Ram Krishn, Yanqing Wang, David W Goodrich, Peter McCue, Andrew Kossenkov, Amy C Mandigo, Karen Knudsen, Paul H Weinreb, Eva Corey, William Kevin Kelly, and Lucia R Languino
SOX10 requirement for melanoma tumor growth is due, in part, to immune-mediated effects, Sheera Rosenbaum, Manoela Tiago, Signe Caksa, Claudia Capparelli, Timothy J. Purwin, Gaurav Kumar, McKenna Glasheen, Danielle Pomante, Daniel Kotas, I Chervoneva, and A E Aplin
The circadian cryptochrome, CRY1, is a pro-tumorigenic factor that rhythmically modulates DNA repair., Ayesha A Shafi, Chris M McNair, Jennifer J McCann, Mohammed Alshalalfa, Anton Shostak, Tesa M Severson, Yanyun Zhu, Andre Bergman, Nicolas Gordon, Amy C Mandigo, Saswati N Chand, Peter Gallagher, Emanuela Dylgjeri, Talya S Laufer, Irina A Vasilevskaya, Matthew J Schiewer, Michael Brunner, Felix Y Feng, Wilbert Zwart, and Karen E Knudsen
Review article: diagnosis, management and patient perspectives of the spectrum of constipation disorders., Amol Sharma, Satish S C Rao, Kimberly Kearns, Kimberly D Orleck, and Scott A Waldman
The Role of miRNAs, miRNA Clusters, and isomiRs in Development of Cancer Stem Cell Populations in Colorectal Cancer., Victoria A Stark, Caroline O B Facey, Vignesh Viswanathan, and Bruce M Boman
Targeted Treatment of Head and Neck (Pre)Cancer: Preclinical Target Identification and Development of Novel Therapeutic Applications, Anne van Harten and Ruud H. Brakenhoff
Point-of-Care Lung Ultrasound for COVID-19: Findings and Prognostic Implications From 105 Consecutive Patients, Kosuke Yasukawa, Taro Minami, David R Boulware, Ayako Shimada, and Ernest A Fischer
miRcorrNet: machine learning-based integration of miRNA and mRNA expression profiles, combined with feature grouping and ranking., Malik Yousef, Gokhan Goy, Ramkrishna Mitra, Christine M. Eischen, Amhar Jabeer, and Burcu Bakir-Gungor
Manuscripts from 2020
Unexpected cell type-dependent effects of autophagy on polyglutamine aggregation revealed by natural genetic variation in C. elegans., J Alexander-Floyd, S Haroon, M Ying, A A Entezari, C Jaeger, M Vermulst, and T Gidalevitz
APC-β-catenin-TCF signaling silences the intestinal guanylin-GUCY2C tumor suppressor axis., Erik S Blomain, Jeffrey A Rappaport, Amanda M Pattison, Babar Bashir, Ellen Caparosa, Jonathan Stem, Adam E Snook, and Scott A Waldman
Autocatalytic Tissue Polymerization Reaction Mechanism in Colorectal Cancer Development and Growth., Bruce M Boman, Arthur Guetter, Ryan M Boman, and Olaf A Runquist
The membrane-associated form of cyclin D1 enhances cellular invasion, Ke Chen, Xuanmao Jiao, Anthony Ashton, Agnese Di Rocco, Timothy G Pestell, Yunguang Sun, Jun Zhao, Mathew C Casimiro, Zhiping Li, Michael P Lisanti, Peter McCue, Duanwen Shen, Samuel Achilefu, Hallgeir Rui, and Richard G Pestell
Endogenous Cyclin D1 Promotes the Rate of Onset and Magnitude of Mitogenic Signaling via Akt1 Ser473 Phosphorylation., Ke Chen, Xuanmao Jiao, Agnese Di Rocco, Duanwen Shen, Shaohua Xu, Adam Ertel, Zuoren Yu, Gabriele Di Sante, Min Wang, Zhiping Li, Timothy G Pestell, Mathew C Casimiro, Emmanuel Skordalakes, Samuel Achilefu, and Richard G Pestell
Development of an abbreviated symptom score for the neonatal abstinence syndrome., I. Chervoneva, S. C. Adeniyi-Jones, F. Blanco, and W. K. Kraft
Chimeric Ad5.F35 vector evades anti-adenovirus serotype 5 neutralization opposing GUCY2C-targeted antitumor immunity, John C. Flickinger, Jagmohan Singh, Robert D Carlson, Elinor Leong, Trevor R. Baybutt, Joshua Barton, Ellen M. Caparosa, Amanda M. Pattison, Jeff A. Rappaport, Jamin Roh, Tingting Zhan, Babar Bashir, Scott A Waldman, and Adam E. Snook
Epidemiology of COVID-19 and Predictors of Outcome in Nigeria: A Single-Center Study., Olayinka Rasheed Ibrahim, Bello Muhammed Suleiman, Suleiman Bello Abdullahi, Taofeek Oloyede, Abdallah Sanda, Maruf Sanusi Gbadamosi, Bashir Olajide Yusuf, Rabilu Yandoma Iliyasu, Lawal Magaji Ibrahim, Adamu Danladi Dawud, Sulaiman Saidu Bashir, Nwawueze Efam Okonta, Wasinda Francis Umar, Abiodun Gbenga Tekobo, Muhammadu Sani Abubakar, Bashir Taiye Aminu, Shuaibu Onoruoyiza Ibrahim, Rasaq Olaosebikan, and Olugbenga Ayodeji Mokuolu
Mobilizing Toxins for Cancer Treatment: Historical Perspectives and Current Strategies., Jessica Kopenhaver, Robert D Carlson, and Adam E Snook
Artificial Intelligence-Powered Search Tools and Resources in the Fight Against COVID-19., Larry J Kricka, Sergei Polevikov, Jason Y Park, Paolo Fortina, Sergio Bernardini, Daniel Satchkov, Valentin Kolesov, and Maxim Grishkov
The αvβ6 integrin in cancer cell-derived small extracellular vesicles enhances angiogenesis., Shiv Ram Krishn, Israa Salem, Fabio Quaglia, Nicole M Naranjo, Ekta Agarwal, Qin Liu, Srawasti Sarker, Jessica Kopenhaver, Peter A McCue, Paul H Weinreb, Shelia M Violette, Dario C Altieri, and Lucia R Languino
iSeqQC: a tool for expression-based quality control in RNA sequencing., Gaurav Kumar, Adam Ertel, George Feldman, Joan Kupper, and Paolo Fortina
Vancomycin in peritoneal dialysis: Clinical pharmacology considerations in therapy., Edwin Lam, Yi Ting Kayla Lien, Walter K. Kraft, Beth Piraino, Valvanera Vozmediano, Stephan Schmidt, and Jingjing Zhang
Twice-Daily Doravirine Overcomes the Interaction Effect from Once-Weekly Rifapentine and Isoniazid in Healthy Volunteers., Edwin Lam, Joseph Schaefer, Richard Zheng, Tingting Zhan, and Walter K. Kraft
Simulation-based mastery learning compared to standard education for discussing diagnostic uncertainty with patients in the emergency department: a randomized controlled trial., Danielle M. McCarthy, Rhea E. Powell, Kenzie A. Cameron, David H. Salzman, Dimitrios Papanagnou, Amanda Doty, Benjamin E. Leiby, Katherine Piserchia, Matthew R. Klein, Xiao C. Zhang, William C. McGaghie, and Kristin L. Rising
Pan-cancer analysis reveals cooperativity of both strands of microRNA that regulate tumorigenesis and patient survival, Ramkrishna Mitra, Clare M. Adams, Wei Jiang, Evan J. Greenawalt, and Christine M. Eischen
