Manuscripts from 2016
Neonatal abstinence syndrome: Pharmacologic strategies for the mother and infant., Walter K. Kraft, Megan W. Stover, and Jonathan M. Davis
Obesity-Induced Colorectal Cancer Is Driven by Caloric Silencing of the Guanylin-GUCY2C Paracrine Signaling Axis., Jieru E. Lin, Francheska Colon-Gonzalez, Erik S. Blomain, Gilbert W. Kim, Amanda Aing, Brian Stoecker, Justin Rock, Adam E. Snook, Tingting Zhan, Terry M. Hyslop, Michal Tomczak, Richard S. Blumberg, and Scott A. Waldman
The Potential Roles of Long Noncoding RNAs (lncRNA) in Glioblastoma Development, Shuang Liu, Ramkrishna Mitra, Ming-Ming Zhao, Wenhong Fan, Christine M. Eischen, Feng Yin, and Zhongming Zhao
Genome-wide redistribution of MeCP2 in dorsal root ganglia after peripheral nerve injury., Melissa T. Manners, Adam Ertel, Yuzhen Tian, and Seena K. Ajit
Role of a plausible nuisance contributor in the declining obesity-mortality risks over time., Tapan Mehta, Nicholas m. Pajewski, Scott W. Keith, Kevin Fontaine, and David B. Allison
Expression of μ-protocadherin is negatively regulated by the activation of the β-catenin signaling pathway in normal and cancer colorectal enterocytes., Lucia Montorsi, Sandra Parenti, Lorena Losi, Fabrizio Ferrarini, Claudia Gemelli, A Rossi, Gianrocco Manco, Stefano Ferrari, Bruno Calabretta, Enrico Tagliafico, Tommaso Zanocco-Marani, and Alexis Grande
Pharmacologic and clinical evaluation of posaconazole., Jason N. Moore, Jason R. Healy, and Walter K. Kraft
Impossibility to eliminate observer effect in the assessment of adherence in clinical trials., Jonathan S. Myers, Scott J. Fudemberg, Robert E. Fintelmann, Lisa A. Hark, Nitasha Khanna, Benjamin E. Leiby, and Michael Waisbourd
A survey of physician receptivity to molecular diagnostic testing and readiness to act on results for early-stage colon cancer patients., Ronald E. Myers, Thomas Wolf, Phillip Shwae, Sarah E. Hegarty, Stephen C. Peiper, and Scott A. Waldman
Reversibility of Apixaban Anticoagulation with a Four-Factor Prothrombin Complex Concentrate in Healthy Volunteers., S Nagalla, Lynda Thomson, Y Oppong, B Bachman, I Chervoneva, and walter k. Kraft
Multi-focal control of mitochondrial gene expression by oncogenic MYC provides potential therapeutic targets in cancer., Amanda R. Oran, Clare M. Adams, Xiao-Yong Zhang, Victoria J. Gennaro, Harla K. Pfeiffer, Hestia S. Mellert, Hans E. Seidel, Kirsten Mascioli, Jordan Kaplan, Mahmoud R. Gaballa, Chen Shen, Isidore Rigoutsos, Michael P. King, Justin L Cotney, Jamie J. Arnold, Suresh D. Sharma, Ubaldo E. Martinez-Outshoorn, Christopher R. Vakoc, Lewis A. Chodosh, James E. Thompson, James E. Bradner, Craig E. Cameron, Gerald S. Shadel, Christine M. Eischen, and Steven B. McMahon
β1 integrin- and JNK-dependent tumor growth upon hypofractionated radiation., Aejaz Sayeed, Huimin Lu, Qin Liu, David Deming, Alexander Duffy, Peter McCue, Adam P. Dicker, Roger J. Davis, Dmitry Gabrilovich, Ulrich Rodeck, Dario C. Altieri, and Lucia R. Languino
The Mitochondrial Unfoldase-Peptidase Complex ClpXP Controls Bioenergetics Stress and Metastasis., Jae Ho Seo, Dayana B. Rivadeneira, M. Cecilia Caino, Young Chan Chae, David W. Speicher, Hsin-Yao Tang, Valentina Vaira, Silvano Bosari, Alessandro Palleschi, Paolo Rampini, Andrew V. Kossenkov, Lucia R. Languino, and Dario C. Altieri
Exosome-mediated Transfer of αvβ3 Integrin from Tumorigenic to Nontumorigenic Cells Promotes a Migratory Phenotype., Amrita Singh, Carmine Fedele, Huimin Lu, Marja T. Nevalainen, James H. Keen, and Lucia R. Languino
Big Data Transforms Discovery-Utilization Therapeutics Continuum., Scott A. Waldman and Andre Terzic
Bioinnovation Enterprise: An engine driving breakthrough therapies., Scott A. Waldman and Andre Terzic
A direct quantification method for measuring plasma MicroRNAs identified potential biomarkers for detecting metastatic breast cancer., Qian Zhao, Shengqiong Deng, Guangxue Wang, Cuicui Liu, Lingyu Meng, Shanshan Qiao, Lei Shen, Yue Zhang, Jinhui Lü, Yuzhen Zhang, Min Wang, Richard Pestell, Chunli Liang, Zuoren Yu, and Wenshu Li
Manuscripts from 2015
Consequence of the tumor-associated conversion to cyclin D1b., Michael A Augello, Lisa D Berman-Booty, Richard Carr, Akihiro Yoshida, Jeffry L Dean, M J Schiewer, Felix Y Feng, Scott A Tomlins, Erhe Gao, Walter J Koch, Jeffrey L Benovic, John Alan Diehl, and Karen E Knudsen
Expression of Interferon Gamma by a Recombinant Rabies Virus Strongly Attenuates the Pathogenicity of the Virus via Induction of Type I Interferon., Darryll A Barkhouse; Samantha A Garcia; Emily K Bongiorno; Aurore Lebrun; Milosz Faber; and D Craig Hooper, PhD
ErbB3-ErbB2 Complexes as a Therapeutic Target in a Subset of Wild-type BRAF/NRAS Cutaneous Melanomas., Claudia Capparelli, Sheera Rosenbaum, Lisa D. Berman-Booty, Amel Salhi, Nadège Gaborit, Tingting Zhan, Inna Chervoneva, Jason Roszik, Scott E. Woodman, Michael A. Davies, Yulius Y. Setiady, Iman Osman, Yosef Yarden, and Andrew E. Aplin
Kinase-independent role of cyclin D1 in chromosomal instability and mammary tumorigenesis., Mathew C Casimiro, Gabriele Disante, Marco Crosariol, Emanuele Loro, William Dampier, Adam Ertel, Zuoren Yu, Elizabeth A Saria, Alexandros Papanikolaou, Z Li, Chenguang Wang, Sankar Addya, Michael P. Lisanti, Paolo Fortina, Robert D Cardiff, Aydin Tozeren, Erik S Knudsen, Andrew Arnold, and Richard Pestell
Paracrine Effect of NRG1 and HGF Drives Resistance to MEK Inhibitors in Metastatic Uveal Melanoma., Hanyin Cheng, Mizue Terai, Ken Kageyama, Shinji Ozaki, Peter McCue, Takami Sato, and Andrew E. Aplin
Association of Adipokines with Insulin Resistance, Microvascular Dysfunction, and Endothelial Dysfunction in Healthy Young Adults., Cindy Cheng, MD, PhD and Constantine Daskalakis
The endogenous cell-fate factor dachshund restrains prostate epithelial cell migration via repression of cytokine secretion via a cxcl signaling module., Ke Chen, Kongming Wu, Xuanmao Jiao, Liping Wang, Xiaoming Ju, Min Wang, Gabriele Disante, Shaohua Xu, Qiong Wang, Kevin Li, Xin Sun, Chongwen Xu, Zhiping Li, Mathew C. Casimiro, Adam Ertel, Sankar Addya, Peter McCue, Michael P. Lisanti, Chenguang Wang, Richard J. Davis, Graeme Mardon, and Richard Pestell
Novel actions of next-generation taxanes benefit advanced stages of prostate cancer., Renée de Leeuw, Lisa D. Berman-Booty, Matthew J. Schiewer, Stephen J Ciment, Robert Den, Adam P. Dicker, William Kelly, Edouard J. Trabulsi, Costas D. Lallas, Leonard G. Gomella, and Karen E. Knudsen
Chromatin to Clinic: The Molecular Rationale for PARP1 Inhibitor Function., Felix Y. Feng, Johann S. de Bono, Mark A. Rubin, and Karen E Knudsen
Deregulation of MiR-34b/Sox2 Predicts Prostate Cancer Progression., Irene Forno, Stefano Ferrero, Maria Veronica Russo, Giacomo Gazzano, Sara Giangiobbe, Emanuele Montanari, Alberto Del Nero, Bernardo Rocco, Giancarlo Albo, Lucia R Languino, Dario C Altieri, Valentina Vaira, and Silvano Bosari
Adolescent and adult African Americans have similar metabolic dyslipidemia., Samuel S. Gidding, Scott W. Keith, and Bonita Falkner
DNA-PKcs-Mediated Transcriptional Regulation Drives Prostate Cancer Progression and Metastasis., Jonathan F Goodwin, Vishal Kothari, Justin M Drake, Shuang Zhao, Emanuela Dylgjeri, Jeffry L. Dean, Matthew J. Schiewer, Christopher McNair, Jennifer K. Jones, Alvaro Aytes, Michael S. Magee, Adam E. Snook, Ziqi Zhu, Robert Den, Ruth C. Birbe, Leonard G. Gomella, Nicholas A. Graham, Ajay A. Vashisht, James A. Wohlschlegel, Thomas G. Graeber, R. Jeffrey Karnes, Mandeep Takhar, Elai Davicioni, Scott A. Tomlins, Cory Abate-Shen, Nima Sharifi, Owen N. Witte, Felix Y. Feng, and Karen E. Knudsen
Ketamine for the treatment of depression in patients receiving hospice care: a retrospective medical record review of thirty-one cases., Alana Iglewicz, Katherine Morrison, Richard A. Nelesen, Tingting Zhan, Boris Iglewicz, Nathan Fairman, Jeremy M. Hirst, and Scott A. Irwin
Structure-Based Screen Identifies a Potent Small Molecule Inhibitor of Stat5a/b with Therapeutic Potential for Prostate Cancer and Chronic Myeloid Leukemia., Zhiyong Liao, Lei Gu, Jenny Vergalli, Samanta A. Mariani, Marco De Dominici, Ravi K. Lokareddy, Ayush Dagvadorj, Puranik Purushottamachar, Peter A. McCue, Edouard J. Trabulsi, Costas D. Lallas, Shilpa Gupta, Elyse Ellsworth, Shauna Blackmon, Adam Ertel, Paolo Fortina, Benjamin E. Leiby, Guanjun Xia, Hallgeir Rui, David T. Hoang, Leonard G Gomella, Gino Cingolani, Vincent Njar, Nagarajan Pattabiraman, Bruno Calabretta, and Marja T. Nevalainen
Cyclin D1 silencing suppresses tumorigenicity, impairs DNA double strand break repair and thus radiosensitizes androgenindependent prostate cancer cells to DNA damage., F Marampon, G L Gravina, Xiaoming Ju, A Vetuschi, R Sferra, Mathew C Casimiro, S Pompili, C Festuccia, A Colapietro, E Gaudio, E Di Cesare, V Tombolini, and Richard Pestell
No Evidence of a Drug-Drug Interaction Between Letermovir (MK-8228) and Mycophenolate Mofetil, WL Marshall; C. Badshah; F. Liu; Walter K. Kraft, MD; F. Colon-Gonzalez; A. van Schanke; CR. Cho; E. Hulskotte; JR Butterton; and EE Marcantonio
Antibiotics for cancer therapy., Richard Pestell and Albert A Rizvanov
GM1 ganglioside in Parkinson's disease: Pilot study of effects on dopamine transporter binding., Jay S. Schneider, Franca Cambi, Stephen M. Gollomp, Hiroto Kuwabara, James R. Brašić, Benjamin E. Leiby, Stephanie Sendek, and Dean F. Wong
NF-κB Regulation of c-FLIP Promotes TNFα-Mediated RAF Inhibitor Resistance in Melanoma., Yongping Shao, Kaitlyn Le, Hanyin Cheng, and Andrew E. Aplin
DICER1 regulated let-7 expression levels in p53-induced cancer repression requires cyclin D1., Xin Sun, Shou-Ching Tang, Chongwen Xu, Chenguang Wang, Sida Qin, Ning Du, Jian Liu, Yiwen Zhang, Xiang Li, Gang Luo, Jie Zhou, Fei Xu, and Hong Ren
Deletion of Cyclophilin D Impairs β-Oxidation and Promotes Glucose Metabolism., Michele Tavecchio, Sofia Lisanti, Michael J Bennett, Lucia R Languino, and Dario C Altieri
The Broad Stroke of Hsp90 Inhibitors: Painting over the RAF Inhibitor Paradox., Michael J Vido and A E Aplin
RAC1 P29S regulates PD-L1 expression in melanoma., Ha Linh Vu, Sheera Rosenbaum, Timothy J. Purwin, Michael A. Davies, and Andrew E. Aplin
Companion diagnostics at the intersection of personalized medicine and healthcare delivery., Scott A Waldman and Andre Terzic
Expression of the IL-11 Gene in Metastatic Cells Is Supported by Runx2-Smad and Runx2-cJun Complexes Induced by TGFβ1., Xuhui Zhang, Hai Wu, Jason R. Dobson, Gillian Browne, Deli Hong, Jacqueline Akech, Lucia R. Languino, Gary S. Stein, and Jane B. Lian
Manuscripts from 2014
AR function in promoting metastatic prostate cancer., Michael A Augello, Robert B Den, and Karen E Knudsen
Evidence for role of acid-sensing ion channels in nucleus ambiguus neurons: essential differences in anesthetized versus awake rats., G Cristina Brailoiu, Elena Deliu, Joseph Altmann, Vineet Chitravanshi, and Eugen Brailoiu
ASA Section on Teaching of Statistics in the Health Sciences: 25 Years Later, Constantine Daskalakis, ScD
Arterial stiffness and wave reflection 1 year after a pregnancy complicated by hypertension., Deborah B Ehrenthal, Neal D Goldstein, Pan Wu, Stephanie Rogers, Raymond R Townsend, and David G Edwards
Suppression of invasion and metastasis of triple-negative breast cancer lines by pharmacological or genetic inhibition of slug activity., Giovanna Ferrari-Amorotti, Claudia Chiodoni, Fei Shen, Sara Cattelani, Angela Rachele Soliera, Gloria Manzotti, Giulia Grisendi, Massimo Dominici, Francesco Rivasi, Mario Paolo Colombo, Alessandro Fatatis, and Bruno Calabretta
Genomics into Healthcare: the 5th Pan Arab Human Genetics Conference and 2013 Golden Helix Symposium., Paolo Fortina, Najib Al Khaja, Mahmoud Taleb Al Ali, Abdul Rezzak Hamzeh, Pratibha Nair, Federico Innocenti, George P. Patrinos, and Larry J. Kricka
Permeation Redux: Thermodynamics and Kinetics of Ion Movement through Potassium Channels., Richard Horn, Benoît Roux, and Johan Aqvist
Hormone whodunit: clues for solving the case of intratumor androgen production., Karen E Knudsen
Posaconazole Tablet Pharmacokinetics: Lack of Effect of Concomitant Medications Altering Gastric pH and Gastric Motility in Healthy Subjects., Walter K. Kraft, Peter S. Chang, Marlou L P S van Iersel, Hetty Waskin, Gopal Krishna, and Wendy M Kersemaekers
miR-221/222 promotes S-phase entry and cellular migration in control of basal-like breast cancer., Yuan Li, Chunli Liang, Haizhong Ma, Qian Zhao, Ying Lu, Zhendong Xiang, Li Li, Jie Qin, Yihan Chen, William C Cho, Richard G Pestell, Li Liang, and Zuoren Yu
Ethanol Pharmacokinetics in Neonates and Infants, Elizabeth Marek, PharmD. and Walter K. Kraft, MD
GUCY2C lysosomotropic endocytosis delivers immunotoxin therapy to metastatic colorectal cancer., Glen P Marszalowicz, Adam E. Snook, Michael Sullivan Magee, Dante Merlino, Lisa D Berman-Booty, and Scott A Waldman
Obesity and mortality: are the risks declining? Evidence from multiple prospective studies in the United States., Tapan S. Mehta, Kevin R. Fontaine, Scott W. Keith, Sripal S. Bangalore, Gustavo de los Campos, Alfred Bartolucci, Nicholas M. Pajewski, and David B. Allison
Depletion of pre-mRNA splicing factor Cdc5L inhibits mitotic progression and triggers mitotic catastrophe., R Mu, Y-B Wang, M Wu, Y Yang, W Song, T Li, W-N Zhang, B Tan, A-L Li, N Wang, Q Xia, W-L Gong, Chenguang Wang, T Zhou, N Guo, Z-H Sang, and H-Y Li
Impact of Preadmission Beta-blocker Use on Cardiac Abnormalities and In-hospital Mortality in Patients with Aneurysmal Subarachnoid Hemorrhage, Toshimasa Okabe, MD; Anushya Jeyabalan, MD; Benjamin E. Leiby, PhD; Fred Rincon, MD; and Walter K. Kraft, MD
The long non-coding RNA PCAT-1 promotes prostate cancer cell proliferation through cMyc., John R. Prensner, Wei Chen, Sumin Han, Matthew K. Iyer, Qi Cao, Vishal Kothari, Joseph R. Evans, Karen E. Knudsen, Michelle T. Paulsen, Mats Ljungman, Theodore S. Lawrence, Arul M. Chinnaiyan, and Felix Y. Feng
Single nucleotide polymorphism of SREBF-1 gene associated with an increased risk of endometrial cancer in Chinese women., Chun-Ping Qiu, Qing-Tao Lv, Samina Dongol, Chenguang Wang, and Jie Jiang
The retinoblastoma tumor suppressor modulates DNA repair and radioresponsiveness., Chellappagounder Thangavel; Ettickan Boopathi; Steve Ciment; Yi Liu; Raymond O'Neill; Ankur Sharma; Steve B McMahon; Hestia Mellert; Sankar Addya; Adam Ertel; Ruth Birbe; Paolo Fortina; Adam Dicker MD, PhD; Karen E Knudsen; and Robert Den MD
Acetylation-defective mutant of Pparγ is associated with decreased lipid synthesis in breast cancer cells., Lifeng Tian, Chenguang Wang, Fred K Hagen, Michael Gormley, Sankar Addya, Raymond Soccio, Mathew C Casimiro, Jie Zhou, Michael J Powell, Ping Xu, Haiteng Deng, Anthony A Sauve, and Richard Pestell
Current Therapeutic Research is Now Indexed on PubMed., John N van den Anker, Karel Allegaert, and Walter K. Kraft
Targeting TBK1 inhibits migration and resistance to MEK inhibitors in mutant NRAS melanoma., Ha Linh Vu and A E Aplin
Managing the innovation supply chain to maximize personalized medicine., Scott A. Waldman and Andre Terzic
CAMK2N1 inhibits prostate cancer progression through androgen receptor-dependent signaling., Tao Wang, Shuiming Guo, Zhuo Liu, Licheng Wu, Mingchao Li, Jun Yang, Ruibao Chen, Xiaming Liu, Hua Xu, Shaoxin Cai, Hui Chen, Weiyong Li, Shaohua Xu, Liang Wang, Zhiquan Hu, Qianyuan Zhuang, Liping Wang, Kongming Wu, Jihong Liu, Zhangqun Ye, Jun-Yuan Ji, Chenguang Wang, and Ke Chen
The tumor suppressive role of CAMK2N1 in castration-resistant prostate cancer., Tao Wang, Zhuo Liu, Shuiming Guo, Licheng Wu, Mingchao Li, Jun Yang, Ruibao Chen, Hua Xu, Shaoxin Cai, Hui Chen, Weiyong Li, Liang Wang, Zhiquan Hu, Qianyuan Zhuang, Shaohua Xu, Liping Wang, Jihong Liu, Zhangqun Ye, Jun-Yuan Ji, Chenguang Wang, and Ke Chen
Tumor radiation therapy creates therapeutic vaccine responses to the colorectal cancer antigen GUCY2C., Matthew Witek, Erik S Blomain, Michael Sullivan Magee, Bo Xiang, Scott A Waldman, and Adam E. Snook
The retinoblastoma tumor suppressor pathway modulates the invasiveness of ErbB2-positive breast cancer., A K Witkiewicz; D W Cox; D Rivadeneira; Adam Ertel; Paolo Fortina; Gordon Schwartz, MD, MBA, FACS; and E S Knudsen
miR-17/20 sensitization of breast cancer cells to chemotherapy-induced apoptosis requires Akt1., Zuoren Yu, Zengguang Xu, Gabriele Disante, Jennifer Wright, Min Wang, Yuan Li, Qian Zhao, Tao Ren, Xiaoming Ju, Ellen Gutman, Guangxue Wang, Sankar Addya, Tieyan Li, Zhendong Xiang, Chenguang Wang, Xiongfei Yang, Xiaolai Yang, and Richard Pestell
Association of leukocyte mitochondrial DNA content with glioma risk: evidence from a Chinese case-control study., Jie Zhang, Deyang Li, Falin Qu, Yibing Chen, Gang Li, Hequn Jiang, Xiaojun Huang, Hushan Yang, and Jinliang Xing
Manuscripts from 2013
Mechanisms of Weight Regain following Weight Loss, Erik Scott Blomain, Dara Anne Dirhan, Michael Anthony Valentino, Gilbert Won Kim, and Scott A Waldman
Cyclin D1 determines estrogen signaling in the mammary gland in vivo., Mathew C Casimiro, Chenguang Wang, Z Li, Gabriele Disante, Nicole E Willmart, Sankar Addya, Lei Chen, Yang Liu, Michael P. Lisanti, and Richard Pestell
Acetylation of the cell-fate factor dachshund determines p53 binding and signaling modules in breast cancer., Ke Chen, Kongming Wu, Michael Gormley, Adam Ertel, Jing Wang, Wei Zhang, Jie Zhou, Gabriele Disante, Zhiping Li, Hallgeir Rui, Andrew A Quong, Steven B McMahon, Haiteng Deng, Michael P Lisanti, Chenguang Wang, and Richard G Pestell
Targeting cell cycle and hormone receptor pathways in cancer., C E S Comstock; M A Augello; J F Goodwin; R de Leeuw; M J Schiewer; W F Ostrander; R A Burkhart; A K McClendon; Peter McCue; Edouard J. Trabulsi; Costas D. Lallas; Leonard G Gomella, MD; M M Centenera; Jonathan Brody, MD; L M Butler; W D Tilley; and K E Knudsen, PhD
The Impact of Community Use of Novel Oral Anticoagulants on an Academic Medical Center, Luis Eraso, MD; Taki Galanis, MD; Kristina Kipp, Pharm.D.; Walter K. Kraft, MD; Michael Palladino, Pharm.D., CACP; Alejandro Perez, MD; Kimberle Ferebee-Spruill, CRNP; Geno Merli, MD; Brian G. Swift, Pharm.D., MBA; Lynda Thomson; and Brittany Vining
Nuclear localization of CPI-17, a protein phosphatase-1 inhibitor protein, affects histone H3 phosphorylation and corresponds to proliferation of cancer and smooth muscle cells., Masumi Eto, Jason A Kirkbride, Rishika Chugh, Nana Kofi Karikari, and Jee In Kim
Intestinal GUCY2C prevents TGF-β secretion coordinating desmoplasia and hyperproliferation in colorectal cancer., Ahmara V Gibbons, Jieru Egeria Lin, Gilbert Won Kim, Glen P Marszalowicz, Peng Li, Brian Arthur Stoecker, Erik S Blomain, Satish Rattan, Adam E. Snook, Stephanie Schulz, and Scott A Waldman
Presence of virus neutralizing antibodies in cerebral spinal fluid correlates with non-lethal rabies in dogs., Clement W Gnanadurai, Ming Zhou, Wenqi He, Christina M Leyson, Chien-Tsun Huang, Gregory Salyards, Stephen B Harvey, Zhenhai Chen, Biao He, Yang Yang, D C Hooper, Berhnard Dietzchold, and Zhen F Fu
A STATement on vemurafenib-resistant melanoma., Edward J Hartsough and A E Aplin
Molecular staging of node negative patients with colorectal cancer., Terry Hyslop and Scott A Waldman
A TH1 immune response efficiently clears rabies virus from the CNS in the absence of inflammation, Aurore Lebrun, Rhonda Kean, Jianwei Li, and Douglas Craig Hooper
Intracellular reprogramming of expression, glycosylation, and function of a plant-derived antiviral therapeutic monoclonal antibody., Jeong-Hwan Lee, Da-Young Park, Kyung-Jin Lee, Young-Kwan Kim, Yang-Kang So, Jae-Sung Ryu, Seung-Han Oh, Yeon-Soo Han, Kinarm Ko, Young-Kug Choo, Sung-Joo Park, Robert Brodzik, Kyoung-Ki Lee, Doo-Byoung Oh, Kyung-A Hwang, Hilary Koprowski, Yong Seong Lee, and Kisung Ko
Increased levels of plasma soluble Sema4D in patients with heart failure., Qiongyu Lu, Ningzheng Dong, Qi Wang, Wenxiu Yi, Yuxin Wang, Shengjie Zhang, Haibo Gu, Xin Zhao, Xiaorong Tang, Boquan Jin, Qingyu Wu, Lawrence F Brass, and Li Zhu
Management of intracranial bleeding associated with dabigatran use in a neuroscience hospital, Alejandro Perez, MD; Lynda Thomson; and Geno J. Merli, MD
Pharmacology and clinical potential of guanylyl cyclase C agonists in the treatment of ulcerative colitis., Giovanni M Pitari
IGF-IR Promotes Prostate Cancer Growth by Stabilizing α5β1 Integrin Protein Levels., Aejaz Sayeed, Carmine Fedele, Marco Trerotola, Kirat K Ganguly, and Lucia R Languino
Dynamic recruitment of microRNAs to their mRNA targets in the regenerating liver., Jonathan Schug, Lindsay B McKenna, Gabriel Walton, Nicholas Hand, Sarmistha Mukherjee, Kow Essuman, Zhongjie Shi, Yan Gao, Karen Markley, Momo Nakagawa, Vasumathi Kameswaran, Anastassios Vourekas, Joshua R Friedman, Klaus H Kaestner, and Linda E Greenbaum
Dual fluorescent molecular substrates selectively report the activation, sustainability and reversibility of cellular PKB/Akt activity., Duanwen Shen, Mingfeng Bai, Rui Tang, Baogang Xu, Xiaoming Ju, Richard Pestell, and Samuel Achilefu
Poor Positive Predictive Value of McConnell’s Sign on Transthoracic Echocardiography for the Diagnosis of Acute Pulmonary Embolism, Urvashi Vaid, MD, MS; Esme Singer, MD; Gregary D. Marhefka, MD; Walter K. Kraft, MD; and Michael Baram, MD, FCCM
Breast cancer antiestrogen resistance 3 (BCAR3) promotes cell motility by regulating actin cytoskeletal and adhesion remodeling in invasive breast cancer cells., Ashley L Wilson, Randy S Schrecengost, Michael S Guerrero, Keena S Thomas, and Amy H Bouton
The TWEAK receptor Fn14 is a therapeutic target in melanoma: immunotoxins targeting Fn14 receptor for malignant melanoma treatment., Hong Zhou, Suhendan Ekmekcioglu, John W Marks, Khalid A Mohamedali, Kaushal Asrani, Keeley K Phillips, Sharron A N Brown, Emily Cheng, Michele B Weiss, Walter N Hittelman, Nhan L Tran, Hideo Yagita, Jeffrey A Winkles, and Michael G Rosenblum
Manuscripts from 2012
Dysregulation of miR-31 and miR-21 Induced by Zinc Deficiency Promotes Esophageal Cancer, Hansjuerg Alder, Cristian Taccioli, Hongping Chen, Yubao Jiang, Karl Smalley, Paolo Fadda, Hatice G. Ozer, Kay Huebner, John Farber, Carlo M. Croce, and Louise Fong
Adaptive upregulation of FOXD3 and resistance to PLX4032/4720-induced cell death in mutant B-RAF melanoma cells., K J Basile, E V Abel, and A E Aplin
Genetic ablation of Cav1 differentially affects melanoma tumor growth and metastasis in mice: role of Cav1 in Shh heterotypic signaling and transendothelial migration., Franco Capozza, Casey Trimmer, Remedios Castello-Cros, Sanjay Katiyar, Diana Whitaker-Menezes, Antonia Follenzi, Marco Crosariol, Gemma Llaverias, Federica Sotgia, Richard G Pestell, and Michael P Lisanti
Cyclin d1 induces chromosomal instability., Mathew C Casimiro and Richard Pestell
Aleuria Aurantia Lectin (AAL)-reactive immunoglobulin G rapidly appears in sera of animals following antigen exposure., Songming Chen, Chen Lu, Hongbo Gu, Anand Mehta, Jianwei Li, Patrick B Romano, David Horn, D Craig Hooper, Carthene R Bazemore-Walker, and Timothy Block
Aleuria Aurantia Lectin (AAL)-Reactive Immunoglobulin G Rapidly Appears in Sera of Animals following Antigen Exposure., Songming Chen, Chen Lu, Hongbo Gu, Anand Mehta, Jianwei Li, Patrick B Romano, David Horn, D Craig Hooper, Carthene R Bazemore-Walker, and Timothy Block
Endogenous inhibitor proteins that connect Ser/Thr kinases and phosphatases in cell signaling., Masumi Eto and David L Brautigan
Neurophysiological Impact and Modeling-independent elucidation of inactivation pathways in A-type K+ channels, J.D. Fineberg, David Ritter, and Manuel Covarrubias
Inflammatory signaling compromises cell responses to interferon alpha., W-C Huangfu, J Qian, C Liu, J Liu, A E Lokshin, D P Baker, H Rui, and S Y Fuchs