Manuscripts from 2015
Adolescent and adult African Americans have similar metabolic dyslipidemia., Samuel S. Gidding, Scott W. Keith, and Bonita Falkner
DNA-PKcs-Mediated Transcriptional Regulation Drives Prostate Cancer Progression and Metastasis., Jonathan F Goodwin, Vishal Kothari, Justin M Drake, Shuang Zhao, Emanuela Dylgjeri, Jeffry L. Dean, Matthew J. Schiewer, Christopher McNair, Jennifer K. Jones, Alvaro Aytes, Michael S. Magee, Adam E. Snook, Ziqi Zhu, Robert Den, Ruth C. Birbe, Leonard G. Gomella, Nicholas A. Graham, Ajay A. Vashisht, James A. Wohlschlegel, Thomas G. Graeber, R. Jeffrey Karnes, Mandeep Takhar, Elai Davicioni, Scott A. Tomlins, Cory Abate-Shen, Nima Sharifi, Owen N. Witte, Felix Y. Feng, and Karen E. Knudsen
Ketamine for the treatment of depression in patients receiving hospice care: a retrospective medical record review of thirty-one cases., Alana Iglewicz, Katherine Morrison, Richard A. Nelesen, Tingting Zhan, Boris Iglewicz, Nathan Fairman, Jeremy M. Hirst, and Scott A. Irwin
Structure-Based Screen Identifies a Potent Small Molecule Inhibitor of Stat5a/b with Therapeutic Potential for Prostate Cancer and Chronic Myeloid Leukemia., Zhiyong Liao, Lei Gu, Jenny Vergalli, Samanta A. Mariani, Marco De Dominici, Ravi K. Lokareddy, Ayush Dagvadorj, Puranik Purushottamachar, Peter A. McCue, Edouard J. Trabulsi, Costas D. Lallas, Shilpa Gupta, Elyse Ellsworth, Shauna Blackmon, Adam Ertel, Paolo Fortina, Benjamin E. Leiby, Guanjun Xia, Hallgeir Rui, David T. Hoang, Leonard G Gomella, Gino Cingolani, Vincent Njar, Nagarajan Pattabiraman, Bruno Calabretta, and Marja T. Nevalainen
Cyclin D1 silencing suppresses tumorigenicity, impairs DNA double strand break repair and thus radiosensitizes androgenindependent prostate cancer cells to DNA damage., F Marampon, G L Gravina, Xiaoming Ju, A Vetuschi, R Sferra, Mathew C Casimiro, S Pompili, C Festuccia, A Colapietro, E Gaudio, E Di Cesare, V Tombolini, and Richard Pestell
No Evidence of a Drug-Drug Interaction Between Letermovir (MK-8228) and Mycophenolate Mofetil, WL Marshall; C. Badshah; F. Liu; Walter K. Kraft, MD; F. Colon-Gonzalez; A. van Schanke; CR. Cho; E. Hulskotte; JR Butterton; and EE Marcantonio
Antibiotics for cancer therapy., Richard Pestell and Albert A Rizvanov
GM1 ganglioside in Parkinson's disease: Pilot study of effects on dopamine transporter binding., Jay S. Schneider, Franca Cambi, Stephen M. Gollomp, Hiroto Kuwabara, James R. Brašić, Benjamin E. Leiby, Stephanie Sendek, and Dean F. Wong
NF-κB Regulation of c-FLIP Promotes TNFα-Mediated RAF Inhibitor Resistance in Melanoma., Yongping Shao, Kaitlyn Le, Hanyin Cheng, and Andrew E. Aplin
DICER1 regulated let-7 expression levels in p53-induced cancer repression requires cyclin D1., Xin Sun, Shou-Ching Tang, Chongwen Xu, Chenguang Wang, Sida Qin, Ning Du, Jian Liu, Yiwen Zhang, Xiang Li, Gang Luo, Jie Zhou, Fei Xu, and Hong Ren
Deletion of Cyclophilin D Impairs β-Oxidation and Promotes Glucose Metabolism., Michele Tavecchio, Sofia Lisanti, Michael J Bennett, Lucia R Languino, and Dario C Altieri
The Broad Stroke of Hsp90 Inhibitors: Painting over the RAF Inhibitor Paradox., Michael J Vido and A E Aplin
RAC1 P29S regulates PD-L1 expression in melanoma., Ha Linh Vu, Sheera Rosenbaum, Timothy J. Purwin, Michael A. Davies, and Andrew E. Aplin
Companion diagnostics at the intersection of personalized medicine and healthcare delivery., Scott A Waldman and Andre Terzic
Expression of the IL-11 Gene in Metastatic Cells Is Supported by Runx2-Smad and Runx2-cJun Complexes Induced by TGFβ1., Xuhui Zhang, Hai Wu, Jason R. Dobson, Gillian Browne, Deli Hong, Jacqueline Akech, Lucia R. Languino, Gary S. Stein, and Jane B. Lian
Manuscripts from 2014
AR function in promoting metastatic prostate cancer., Michael A Augello, Robert B Den, and Karen E Knudsen
Evidence for role of acid-sensing ion channels in nucleus ambiguus neurons: essential differences in anesthetized versus awake rats., G Cristina Brailoiu, Elena Deliu, Joseph Altmann, Vineet Chitravanshi, and Eugen Brailoiu
ASA Section on Teaching of Statistics in the Health Sciences: 25 Years Later, Constantine Daskalakis, ScD
Arterial stiffness and wave reflection 1 year after a pregnancy complicated by hypertension., Deborah B Ehrenthal, Neal D Goldstein, Pan Wu, Stephanie Rogers, Raymond R Townsend, and David G Edwards
Suppression of invasion and metastasis of triple-negative breast cancer lines by pharmacological or genetic inhibition of slug activity., Giovanna Ferrari-Amorotti, Claudia Chiodoni, Fei Shen, Sara Cattelani, Angela Rachele Soliera, Gloria Manzotti, Giulia Grisendi, Massimo Dominici, Francesco Rivasi, Mario Paolo Colombo, Alessandro Fatatis, and Bruno Calabretta
Genomics into Healthcare: the 5th Pan Arab Human Genetics Conference and 2013 Golden Helix Symposium., Paolo Fortina, Najib Al Khaja, Mahmoud Taleb Al Ali, Abdul Rezzak Hamzeh, Pratibha Nair, Federico Innocenti, George P. Patrinos, and Larry J. Kricka
Permeation Redux: Thermodynamics and Kinetics of Ion Movement through Potassium Channels., Richard Horn, Benoît Roux, and Johan Aqvist
Hormone whodunit: clues for solving the case of intratumor androgen production., Karen E Knudsen
Posaconazole Tablet Pharmacokinetics: Lack of Effect of Concomitant Medications Altering Gastric pH and Gastric Motility in Healthy Subjects., Walter K. Kraft, Peter S. Chang, Marlou L P S van Iersel, Hetty Waskin, Gopal Krishna, and Wendy M Kersemaekers
miR-221/222 promotes S-phase entry and cellular migration in control of basal-like breast cancer., Yuan Li, Chunli Liang, Haizhong Ma, Qian Zhao, Ying Lu, Zhendong Xiang, Li Li, Jie Qin, Yihan Chen, William C Cho, Richard G Pestell, Li Liang, and Zuoren Yu
Ethanol Pharmacokinetics in Neonates and Infants, Elizabeth Marek, PharmD. and Walter K. Kraft, MD
GUCY2C lysosomotropic endocytosis delivers immunotoxin therapy to metastatic colorectal cancer., Glen P Marszalowicz, Adam E. Snook, Michael Sullivan Magee, Dante Merlino, Lisa D Berman-Booty, and Scott A Waldman
Obesity and mortality: are the risks declining? Evidence from multiple prospective studies in the United States., Tapan S. Mehta, Kevin R. Fontaine, Scott W. Keith, Sripal S. Bangalore, Gustavo de los Campos, Alfred Bartolucci, Nicholas M. Pajewski, and David B. Allison
Depletion of pre-mRNA splicing factor Cdc5L inhibits mitotic progression and triggers mitotic catastrophe., R Mu, Y-B Wang, M Wu, Y Yang, W Song, T Li, W-N Zhang, B Tan, A-L Li, N Wang, Q Xia, W-L Gong, Chenguang Wang, T Zhou, N Guo, Z-H Sang, and H-Y Li
Impact of Preadmission Beta-blocker Use on Cardiac Abnormalities and In-hospital Mortality in Patients with Aneurysmal Subarachnoid Hemorrhage, Toshimasa Okabe, MD; Anushya Jeyabalan, MD; Benjamin E. Leiby, PhD; Fred Rincon, MD; and Walter K. Kraft, MD
The long non-coding RNA PCAT-1 promotes prostate cancer cell proliferation through cMyc., John R. Prensner, Wei Chen, Sumin Han, Matthew K. Iyer, Qi Cao, Vishal Kothari, Joseph R. Evans, Karen E. Knudsen, Michelle T. Paulsen, Mats Ljungman, Theodore S. Lawrence, Arul M. Chinnaiyan, and Felix Y. Feng
Single nucleotide polymorphism of SREBF-1 gene associated with an increased risk of endometrial cancer in Chinese women., Chun-Ping Qiu, Qing-Tao Lv, Samina Dongol, Chenguang Wang, and Jie Jiang
The retinoblastoma tumor suppressor modulates DNA repair and radioresponsiveness., Chellappagounder Thangavel; Ettickan Boopathi; Steve Ciment; Yi Liu; Raymond O'Neill; Ankur Sharma; Steve B McMahon; Hestia Mellert; Sankar Addya; Adam Ertel; Ruth Birbe; Paolo Fortina; Adam Dicker MD, PhD; Karen E Knudsen; and Robert Den MD
Acetylation-defective mutant of Pparγ is associated with decreased lipid synthesis in breast cancer cells., Lifeng Tian, Chenguang Wang, Fred K Hagen, Michael Gormley, Sankar Addya, Raymond Soccio, Mathew C Casimiro, Jie Zhou, Michael J Powell, Ping Xu, Haiteng Deng, Anthony A Sauve, and Richard Pestell
Current Therapeutic Research is Now Indexed on PubMed., John N van den Anker, Karel Allegaert, and Walter K. Kraft
Targeting TBK1 inhibits migration and resistance to MEK inhibitors in mutant NRAS melanoma., Ha Linh Vu and A E Aplin
Managing the innovation supply chain to maximize personalized medicine., Scott A. Waldman and Andre Terzic
CAMK2N1 inhibits prostate cancer progression through androgen receptor-dependent signaling., Tao Wang, Shuiming Guo, Zhuo Liu, Licheng Wu, Mingchao Li, Jun Yang, Ruibao Chen, Xiaming Liu, Hua Xu, Shaoxin Cai, Hui Chen, Weiyong Li, Shaohua Xu, Liang Wang, Zhiquan Hu, Qianyuan Zhuang, Liping Wang, Kongming Wu, Jihong Liu, Zhangqun Ye, Jun-Yuan Ji, Chenguang Wang, and Ke Chen
The tumor suppressive role of CAMK2N1 in castration-resistant prostate cancer., Tao Wang, Zhuo Liu, Shuiming Guo, Licheng Wu, Mingchao Li, Jun Yang, Ruibao Chen, Hua Xu, Shaoxin Cai, Hui Chen, Weiyong Li, Liang Wang, Zhiquan Hu, Qianyuan Zhuang, Shaohua Xu, Liping Wang, Jihong Liu, Zhangqun Ye, Jun-Yuan Ji, Chenguang Wang, and Ke Chen
Tumor radiation therapy creates therapeutic vaccine responses to the colorectal cancer antigen GUCY2C., Matthew Witek, Erik S Blomain, Michael Sullivan Magee, Bo Xiang, Scott A Waldman, and Adam E. Snook
The retinoblastoma tumor suppressor pathway modulates the invasiveness of ErbB2-positive breast cancer., A K Witkiewicz; D W Cox; D Rivadeneira; Adam Ertel; Paolo Fortina; Gordon Schwartz, MD, MBA, FACS; and E S Knudsen
miR-17/20 sensitization of breast cancer cells to chemotherapy-induced apoptosis requires Akt1., Zuoren Yu, Zengguang Xu, Gabriele Disante, Jennifer Wright, Min Wang, Yuan Li, Qian Zhao, Tao Ren, Xiaoming Ju, Ellen Gutman, Guangxue Wang, Sankar Addya, Tieyan Li, Zhendong Xiang, Chenguang Wang, Xiongfei Yang, Xiaolai Yang, and Richard Pestell
Association of leukocyte mitochondrial DNA content with glioma risk: evidence from a Chinese case-control study., Jie Zhang, Deyang Li, Falin Qu, Yibing Chen, Gang Li, Hequn Jiang, Xiaojun Huang, Hushan Yang, and Jinliang Xing
Manuscripts from 2013
Mechanisms of Weight Regain following Weight Loss, Erik Scott Blomain, Dara Anne Dirhan, Michael Anthony Valentino, Gilbert Won Kim, and Scott A Waldman
Cyclin D1 determines estrogen signaling in the mammary gland in vivo., Mathew C Casimiro, Chenguang Wang, Z Li, Gabriele Disante, Nicole E Willmart, Sankar Addya, Lei Chen, Yang Liu, Michael P. Lisanti, and Richard Pestell
Acetylation of the cell-fate factor dachshund determines p53 binding and signaling modules in breast cancer., Ke Chen, Kongming Wu, Michael Gormley, Adam Ertel, Jing Wang, Wei Zhang, Jie Zhou, Gabriele Disante, Zhiping Li, Hallgeir Rui, Andrew A Quong, Steven B McMahon, Haiteng Deng, Michael P Lisanti, Chenguang Wang, and Richard G Pestell
Targeting cell cycle and hormone receptor pathways in cancer., C E S Comstock; M A Augello; J F Goodwin; R de Leeuw; M J Schiewer; W F Ostrander; R A Burkhart; A K McClendon; Peter McCue; Edouard J. Trabulsi; Costas D. Lallas; Leonard G Gomella, MD; M M Centenera; Jonathan Brody, MD; L M Butler; W D Tilley; and K E Knudsen, PhD
The Impact of Community Use of Novel Oral Anticoagulants on an Academic Medical Center, Luis Eraso, MD; Taki Galanis, MD; Kristina Kipp, Pharm.D.; Walter K. Kraft, MD; Michael Palladino, Pharm.D., CACP; Alejandro Perez, MD; Kimberle Ferebee-Spruill, CRNP; Geno Merli, MD; Brian G. Swift, Pharm.D., MBA; Lynda Thomson; and Brittany Vining
Nuclear localization of CPI-17, a protein phosphatase-1 inhibitor protein, affects histone H3 phosphorylation and corresponds to proliferation of cancer and smooth muscle cells., Masumi Eto, Jason A Kirkbride, Rishika Chugh, Nana Kofi Karikari, and Jee In Kim
Intestinal GUCY2C prevents TGF-β secretion coordinating desmoplasia and hyperproliferation in colorectal cancer., Ahmara V Gibbons, Jieru Egeria Lin, Gilbert Won Kim, Glen P Marszalowicz, Peng Li, Brian Arthur Stoecker, Erik S Blomain, Satish Rattan, Adam E. Snook, Stephanie Schulz, and Scott A Waldman
Presence of virus neutralizing antibodies in cerebral spinal fluid correlates with non-lethal rabies in dogs., Clement W Gnanadurai, Ming Zhou, Wenqi He, Christina M Leyson, Chien-Tsun Huang, Gregory Salyards, Stephen B Harvey, Zhenhai Chen, Biao He, Yang Yang, D C Hooper, Berhnard Dietzchold, and Zhen F Fu
A STATement on vemurafenib-resistant melanoma., Edward J Hartsough and A E Aplin
Molecular staging of node negative patients with colorectal cancer., Terry Hyslop and Scott A Waldman
A TH1 immune response efficiently clears rabies virus from the CNS in the absence of inflammation, Aurore Lebrun, Rhonda Kean, Jianwei Li, and Douglas Craig Hooper
Intracellular reprogramming of expression, glycosylation, and function of a plant-derived antiviral therapeutic monoclonal antibody., Jeong-Hwan Lee, Da-Young Park, Kyung-Jin Lee, Young-Kwan Kim, Yang-Kang So, Jae-Sung Ryu, Seung-Han Oh, Yeon-Soo Han, Kinarm Ko, Young-Kug Choo, Sung-Joo Park, Robert Brodzik, Kyoung-Ki Lee, Doo-Byoung Oh, Kyung-A Hwang, Hilary Koprowski, Yong Seong Lee, and Kisung Ko
Increased levels of plasma soluble Sema4D in patients with heart failure., Qiongyu Lu, Ningzheng Dong, Qi Wang, Wenxiu Yi, Yuxin Wang, Shengjie Zhang, Haibo Gu, Xin Zhao, Xiaorong Tang, Boquan Jin, Qingyu Wu, Lawrence F Brass, and Li Zhu
Management of intracranial bleeding associated with dabigatran use in a neuroscience hospital, Alejandro Perez, MD; Lynda Thomson; and Geno J. Merli, MD
Pharmacology and clinical potential of guanylyl cyclase C agonists in the treatment of ulcerative colitis., Giovanni M Pitari
IGF-IR Promotes Prostate Cancer Growth by Stabilizing α5β1 Integrin Protein Levels., Aejaz Sayeed, Carmine Fedele, Marco Trerotola, Kirat K Ganguly, and Lucia R Languino
Dynamic recruitment of microRNAs to their mRNA targets in the regenerating liver., Jonathan Schug, Lindsay B McKenna, Gabriel Walton, Nicholas Hand, Sarmistha Mukherjee, Kow Essuman, Zhongjie Shi, Yan Gao, Karen Markley, Momo Nakagawa, Vasumathi Kameswaran, Anastassios Vourekas, Joshua R Friedman, Klaus H Kaestner, and Linda E Greenbaum
Dual fluorescent molecular substrates selectively report the activation, sustainability and reversibility of cellular PKB/Akt activity., Duanwen Shen, Mingfeng Bai, Rui Tang, Baogang Xu, Xiaoming Ju, Richard Pestell, and Samuel Achilefu
Poor Positive Predictive Value of McConnell’s Sign on Transthoracic Echocardiography for the Diagnosis of Acute Pulmonary Embolism, Urvashi Vaid, MD, MS; Esme Singer, MD; Gregary D. Marhefka, MD; Walter K. Kraft, MD; and Michael Baram, MD, FCCM
Breast cancer antiestrogen resistance 3 (BCAR3) promotes cell motility by regulating actin cytoskeletal and adhesion remodeling in invasive breast cancer cells., Ashley L Wilson, Randy S Schrecengost, Michael S Guerrero, Keena S Thomas, and Amy H Bouton
The TWEAK receptor Fn14 is a therapeutic target in melanoma: immunotoxins targeting Fn14 receptor for malignant melanoma treatment., Hong Zhou, Suhendan Ekmekcioglu, John W Marks, Khalid A Mohamedali, Kaushal Asrani, Keeley K Phillips, Sharron A N Brown, Emily Cheng, Michele B Weiss, Walter N Hittelman, Nhan L Tran, Hideo Yagita, Jeffrey A Winkles, and Michael G Rosenblum
Manuscripts from 2012
Dysregulation of miR-31 and miR-21 Induced by Zinc Deficiency Promotes Esophageal Cancer, Hansjuerg Alder, Cristian Taccioli, Hongping Chen, Yubao Jiang, Karl Smalley, Paolo Fadda, Hatice G. Ozer, Kay Huebner, John Farber, Carlo M. Croce, and Louise Fong
Adaptive upregulation of FOXD3 and resistance to PLX4032/4720-induced cell death in mutant B-RAF melanoma cells., K J Basile, E V Abel, and A E Aplin
Genetic ablation of Cav1 differentially affects melanoma tumor growth and metastasis in mice: role of Cav1 in Shh heterotypic signaling and transendothelial migration., Franco Capozza, Casey Trimmer, Remedios Castello-Cros, Sanjay Katiyar, Diana Whitaker-Menezes, Antonia Follenzi, Marco Crosariol, Gemma Llaverias, Federica Sotgia, Richard G Pestell, and Michael P Lisanti
Cyclin d1 induces chromosomal instability., Mathew C Casimiro and Richard Pestell
Aleuria Aurantia Lectin (AAL)-Reactive Immunoglobulin G Rapidly Appears in Sera of Animals following Antigen Exposure., Songming Chen, Chen Lu, Hongbo Gu, Anand Mehta, Jianwei Li, Patrick B Romano, David Horn, D Craig Hooper, Carthene R Bazemore-Walker, and Timothy Block
Aleuria Aurantia Lectin (AAL)-reactive immunoglobulin G rapidly appears in sera of animals following antigen exposure., Songming Chen, Chen Lu, Hongbo Gu, Anand Mehta, Jianwei Li, Patrick B Romano, David Horn, D Craig Hooper, Carthene R Bazemore-Walker, and Timothy Block
Endogenous inhibitor proteins that connect Ser/Thr kinases and phosphatases in cell signaling., Masumi Eto and David L Brautigan
Neurophysiological Impact and Modeling-independent elucidation of inactivation pathways in A-type K+ channels, J.D. Fineberg, David Ritter, and Manuel Covarrubias
Inflammatory signaling compromises cell responses to interferon alpha., W-C Huangfu, J Qian, C Liu, J Liu, A E Lokshin, D P Baker, H Rui, and S Y Fuchs
Analytic lymph node number establishes staging accuracy by occult tumor burden in colorectal cancer., Terry Hyslop, David S. Weinberg, Stephanie Schulz, Alan Barkun, and Scott A. Waldman
GSK3β inhibition blocks melanoma cell/host interactions by downregulating N-cadherin expression and decreasing FAK phosphorylation., Jobin K John, Kim H T Paraiso, Vito W Rebecca, Liliana P Cantini, Ethan V Abel, Nicholas Pagano, Eric Meggers, Rahel Mathew, Clemens Krepler, Victoria Izumi, Bin Fang, John M Koomen, Jane L Messina, Meenhard Herlyn, and Keiran S M Smalley
Initial experience with Imacor hTEE-guided management of patients following transplant and mechanical circulatory support., Christopher Kang, Hitoshi Hirose, Harold Hasting, and
Cyclin D1 goes metabolic: dual functions of cyclin D1 in regulating lipogenesis., Karen E Knudsen
Effect of Concomitant Medications Affecting Gastric pH and Motility on Posaconazole Tablet Pharmacokinetics, Walter K. Kraft, P. Chang, MLPS Van Iersel, H. Waskin, G. Krishna, and W. Kersemaekers
Pharmacologic management of the opioid neonatal abstinence syndrome., Walter K. Kraft and John N van den Anker
Healthy Volunteer Registries and Ethical Research Principles, Erine A. Kupetsky-Rincon and Walter K. Kraft
Successful management of bleeding complications in patients supported with extracorporeal membrane oxygenation with primary respiratory failure., K Lamb, Sw Cowan, N Evans, H Pitcher, T Moritz, M Lazar, H Hirose, and Nc Cavarocchi
GUCY2C Opposes Systemic Genotoxic Tumorigenesis by Regulating AKT-Dependent Intestinal Barrier Integrity, Jieru Egeria Lin, Adam Eugene Snook, Peng Li, Brian Arthur Stoecker, Gilbert Won Kim, Michael Sullivan Magee, Alex Vladimir Mejia Garcia, Michael Anthony Valentino, Terry Hyslop, Stephanie Schulz, and Scott Arthur Waldman
Molecular staging individualizing cancer management, Alex Mejia, Stephanie Schulz, Terry Hyslop, David S. Weinberg, and Scott A. Waldman
Expression of cyclin D1a and D1b as predictive factors for treatment response in colorectal cancer., M P Myklebust, Z Li, T H Tran, H Rui, E S Knudsen, H Elsaleh, Ø Fluge, B Vonen, H E Myrvold, S Leh, K M Tveit, R G Pestell, and O Dahl
MK-0448, a Specific Kv1.5 Inhibitor: Safety, Pharmacokinetics and Pharmacodynamic Electrophysiology in Experimental Animal Models and in Humans., Behzad B. Pavri, Howard E Greenberg, Walter K. Kraft, Nicole Lazarus, Joseph J Lynch, Joseph J Salata, Mark T Bilodeau, Christopher P Regan, Gary Stump, Li Fan, Anish Mehta, John A Wagner, David E Gutstein, and Daniel Bloomfield
Inflammation, organomegaly, and muscle wasting despite hyperphagia in a mouse model of burn cachexia., Felipe E Pedroso, Paul B Spalding, Michael C Cheung, Relin Yang, Juan C Gutierrez, Andrea Bonetto, Rui Zhan, Ho Lam Chan, Nicholas Namias, Leonidas G Koniaris, and Teresa A Zimmers
ERK2 phosphorylation of serine 77 regulates Bmf pro-apoptotic activity., Y Shao and A E Aplin
Signal transducer and activator of transcription-5 mediates neuronal apoptosis induced by inhibition of Rac GTPase activity., Trisha R Stankiewicz, F Alexandra Loucks, Emily K Schroeder, Marja T Nevalainen, Kenneth L Tyler, Klaus Aktories, Ron J Bouchard, and Daniel A Linseman
Trop-2 inhibits prostate cancer cell adhesion to fibronectin through the β1 integrin-RACK1 axis., Marco Trerotola, Jing Li, Saverio Alberti, and Lucia R. Languino
Advancing pharmacometrics and systems pharmacology., Scott A. Waldman and Andre Terzic
The value proposition of molecular medicine., Scott A. Waldman and Andre Terzic
Small non-coding RNAs govern mammary gland tumorigenesis., Zuoren Yu and Richard Pestell
Identification of the functional binding pocket for compounds targeting small-conductance Ca²⁺-activated potassium channels., Miao Zhang, John M Pascal, Marcel Schumann, Roger S Armen, and Ji-Fang Zhang
Regulation of lipogenesis by cyclin-dependent kinase 8-mediated control of SREBP-1., Xiaoping Zhao, Daorong Feng, Qun Wang, Arian Abdulla, Xiao-Jun Xie, Jie Zhou, Yan Sun, Ellen S Yang, Lu-Ping Liu, Bhavapriya Vaitheesvaran, Lauren Bridges, Irwin J Kurland, Randy Strich, Jian-Quan Ni, Chenguang Wang, Johan Ericsson, Jeffrey E Pessin, Jun-Yuan Ji, and Fajun Yang
Phosphorylation of vasodilator-stimulated phosphoprotein Ser239 suppresses filopodia and invadopodia in colon cancer., David S Zuzga, Joshua Pelta-Heller, Peng Li, Alessandro Bombonati, Scott A Waldman, and Giovanni Mario Pitari
Manuscripts from 2011
Analysis of the proteome of human airway epithelial secretions., Mehboob Ali, Erik P Lillehoj, Yongsung Park, Yoshiyuki Kyo, and K Chul Kim
Formulation of buprenorphine for sublingual use in neonates., Ellena A Anagnostis, Rania E Sadaka, Linda A Sailor, David E Moody, Kevin C Dysart, and Walter k. Kraft
Mechanisms of resistance to RAF inhibitors in melanoma., A E Aplin, Fred M Kaplan, and Yongping Shao
The effects of laropiprant, a selective prostaglandin D₂ receptor 1 antagonist, on the antiplatelet activity of clopidogrel or aspirin., Aimee Dallob, Wen-Lin Luo, Julie Mabalot Luk, Lisa Ratcliffe, Amy O Johnson-Levonas, Jules I Schwartz, Victor Dishy, Walter K. Kraft, Jan N De Hoon, Anne Van Hecken, Inge De Lepeleire, Waldemar Radziszewski, John A Wagner, and Eseng Lai
Tissue-specific regulation of mouse microRNA genes in endoderm-derived tissues., Yan Gao, Jonathan Schug, Lindsay B McKenna, John Le Lay, Klaus H Kaestner, and Linda E Greenbaum
