Document Type
Article
Publication Date
10-1-2021
Abstract
The Concise Guide to PHARMACOLOGY 2021/22 is the fifth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of nearly 1900 human drug targets with an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. Although the Concise Guide constitutes over 500 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point-in-time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/bph.15541. Catalytic receptors are one of the six major pharmacological targets into which the Guide is divided, with the others being: G protein-coupled receptors, ion channels, nuclear hormone receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid-2021, and supersedes data presented in the 2019/20, 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature and Standards Committee of the International Union of Basic and Clinical Pharmacology (NC-IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.
Recommended Citation
Alexander, Stephen PH; Fabbro, Doriano; Kelly, Eamonn; Mathie, Alistair; Peters, John A; Veale, Emma L; Armstrong, Jane F; Faccenda, Elena; Harding, Simon D; Pawson, Adam J; Southan, Christopher; Davies, Jamie A; Beuve, Annie; Brouckaert, Peter; Bryant, Clare; Burnett, John C; Farndale, Richard W; Friebe, Andreas; Garthwaite, John; Hobbs, Adrian J; Jarvis, Gavin E; Kuhn, Michaela; MacEwan, David; Monie, Tom P; Papapetropoulos, Andreas; Potter, Lincoln R; Schmidt, Harald H H W; Szabo, Csaba; and Waldman, Scott A, "THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Catalytic receptors" (2021). Department of Pharmacology and Experimental Therapeutics Faculty Papers. Paper 137.
https://jdc.jefferson.edu/petfp/137
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.
PubMed ID
34529829
Language
English
Comments
This article is the author’s final published version in British Journal of Pharmacology, Volume 178, Issue S1, October 2021, Pages S264 - S312.
The published version is available at https://doi.org/10.1111/bph.15541. Copyright © Alexander et al.