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Manuscripts from 2015

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Murine CMV Infection Induces the Continuous Production of Mucosal Resident T Cells., Corinne J Smith, Sofia Caldeira-Dantas, Holly Turula, and Christopher M. Snyder

Manuscripts from 2014

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Core-based lipid nanoparticles as a nanoplatform for delivery of near-infrared fluorescent imaging agents., Nadia Anikeeva, Yuri Sykulev, Edward J Delikatny, and Anatoliy V Popov

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Vaccination with a genetically modified Brugia malayi cysteine protease inhibitor-2 reduces adult parasite numbers and affects the fertility of female worms following a subcutaneous challenge of Mongolian gerbils (Meriones unguiculatus) with B. malayi infective larvae., Sridhar Arumugam, Junfei Wei, Danielle Ward, David Abraham, Sara Lustigman, Bin Zhan, and Thomas R. Klei

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Vaccination with recombinant Brugia malayi cystatin proteins alters worm migration, homing and final niche selection following a subcutaneous challenge of Mongolian gerbils (Meriones unguiculatus) with B. malayi infective larvae., Sridhar Arumugam, Bin Zhan, David Abraham, Danielle Ward, Sara Lustigman, and Thomas R Klei

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Extracellular traps are associated with human and mouse neutrophil and macrophage mediated killing of larval Strongyloides stercoralis., Sandra Bonne-Annee, Laura A. Kerepesi, Jessica A. Hess, Jordan Wesolowski, Fabienne Paumet, James B. Lok, Thomas J. Nolan, and David Abraham

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MyD88-Dependent Immunity to a Natural Model of Vaccinia Virus Infection Does Not Involve Toll-Like Receptor 2., Michael L Davies, Janet J Sei, Nicholas A Siciliano, Ren-Huan Xu, Felicia Roscoe, Luis J Sigal, Laurence C. Eisenlohr, and Christopher C Norbury

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Efficient B cell responses to Borrelia hermsii infection depend on BAFF and BAFFR but not TACI., Gregory S. Dickinson, PhD; Guizhi Sun; Richard J Bram; and Kishore Alugupalli

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Interleukin-7-dependent B lymphocytes are required for the anti-pneumococcal polysaccharide response and protective immunity to Streptococcus pneumoniae, Gregory S. Dickinson, PhD; Raja Vuyyuru; Timothy L. Manser, PhD; John F. Kerney; and Kishore Alugupalli, PhD

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Small-Molecule Probes Targeting the Viral PPxY-Host Nedd4 Interface Block Egress of a Broad Range of RNA Viruses., Ziying Han, Jianhong Lu, Yuliang Liu, Benjamin Davis, Michael S Lee, Mark A Olson, Gordon Ruthel, Bruce D Freedman, Matthias J. Schnell, Jay E Wrobel, Allen B Reitz, and Ronald N Harty

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Epithelial Immunization Induces Polyfunctional CD8+ T Cells and Optimal Mousepox Protection., Adam R Hersperger, Nicholas A Siciliano, Brian C DeHaven, Adam E. Snook, and Laurence C. Eisenlohr

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Vaccines to combat river blindness: expression, selection and formulation of vaccines against infection with Onchocerca volvulus in a mouse model., Jessica A. Hess, Bin Zhan, Sandra Bonne-Annee, Jessica M. Deckman, Maria Elena Bottazzi, Peter J. Hotez, Thomas R R. Klei, Sara Lustigman, and David Abraham

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Characterization of T-bet and eomes in peripheral human immune cells., James J. Knox, Gabriela L. Cosma, Michael R. Betts, and Laura M. McLane

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ICAM-1-Based Rabies Virus Vaccine Shows Increased Infection and Activation of Primary Murine B Cells In Vitro and Enhanced Antibody Titers In-Vivo., James E Norton, Andrew G Lytle, Shixue Shen, Evgeni P Tzvetkov, Corin L Dorfmeier, and James P McGettigan

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IDO2 in Immunomodulation and Autoimmune Disease., George C Prendergast, Richard Metz, Alexander J Muller, Lauren M F Merlo, and Laura Mandik-Nayak

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CD27high/KLRG1low CD8+ T cells that persist throughout MCMV infection are highly expansive and have the ability to reestablish MCMV immunity, Michael Quinn, Holly Turula, and Christopher M. Snyder

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Limited Brain Metabolism Changes Differentiate between the Progression and Clearance of Rabies Virus., Keith Schutsky, Carla Portocarrero, D Craig Hooper, Bernhard Dietzschold, and Milosz Faber

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Impact of distinct poxvirus infections on the specificities and functionalities of CD4+ T cell responses., Nicholas A Siciliano, Adam R Hersperger, Aimee M Lacuanan, Ren-Huan Xu, John Sidney, Alessandro Sette, Luis J Sigal, and Laurence C. Eisenlohr

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Systemic hematogenous maintenance of memory inflation by MCMV infection., Corinne J Smith, Holly Turula, and Christopher M. Snyder

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Monitoring Cancer Therapy by mRNA PET Imaging, Eric Wickstrom

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Resolving the titer of murine cytomegalovirus by plaque assay using the M2-10B4 cell line and a low viscosity overlay., Katherine A Zurbach, Toktam Moghbeli, and Christopher M Snyder

Manuscripts from 2013

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Antibody quality and protection from lethal ebola virus challenge in nonhuman primates immunized with rabies virus based bivalent vaccine., Joseph E Blaney, Andrea Marzi, Mallory Willet, Amy B Papaneri, Christoph Wirblich, Friederike Feldmann, Michael Holbrook, Peter Jahrling, Heinz Feldmann, and Matthias J Schnell

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Isolated laryngeal leishmaniasis in immunocompetent patients: an underdiagnosed disease., Salvatore Cocuzza, Alessio Strazzulla, Marilia Rita Pinzone, Stefano Cosentino, Agostino Serra, Rosario Caltabiano, Salvatore Lanzafame, Bruno Cacopardo, and Giuseppe Nunnari

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Investigating the role for IL-21 in rabies virus vaccine-induced immunity., Corin L Dorfmeier, Evgeni P Tzvetkov, Anthony Gatt, and James P McGettigan

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Competition for antigen at the level of the APC is a major determinant of immunodominance during memory inflation in murine cytomegalovirus infection., Lila A Farrington, Tameka A Smith, Finn Grey, Ann B Hill, and Christopher M. Snyder

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Snapin, Positive Regulator of Stimulation- Induced Ca(2+) Release through RyR, Is Necessary for HIV-1 Replication in T Cells., Shigemi M Kinoshita, Amane Kogure, Shizuka Taguchi, and Garry P Nolan

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A public health response against Strongyloides stercoralis: time to look at soil-transmitted helminthiasis in full., Alejandro J Krolewiecki, Patrick Lammie, Julie Jacobson, Albis-Francesco Gabrielli, Bruno Levecke, Eugenia Socias, Luis M Arias, Nicanor Sosa, David Abraham, Ruben Cimino, Adriana Echazú, Favio Crudo, Jozef Vercruysse, and Marco Albonico

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Comparison of Heterologous Prime-Boost Strategies against Human Immunodeficiency Virus Type 1 Gag Using Negative Stranded RNA Viruses., Tessa M Lawrence, Celestine N Wanjalla, Emily A Gomme, Christoph Wirblich, Anthony Gatt, Elena Carnero, Adolfo García-Sastre, Douglas S Lyles, James P McGettigan, and Matthias J Schnell

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Collagen Content in Skin and Internal Organs of the Tight Skin Mouse: An Animal Model of Scleroderma., Jayanthi Manne, Marina Markova, Linda D Siracusa, and Sergio A Jimenez

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Toward a Network Model of MHC Class II-Restricted Antigen Processing., Michael A Miller, Asha Purnima V Ganesan, and Laurence C. Eisenlohr

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Two coiled-coil domains of Chlamydia trachomatis IncA affect membrane fusion events during infection., Erik Ronzone and Fabienne Paumet

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Competition for antigen selects T cell responses that undergo memory inflation and maintains clonal dominance during MCMV infection, Holly Turula, Lila A. Farrington, Corinne Smith, Ann B. Hill, and Christopher M Snyder

Manuscripts from 2012

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Evidence that the density of self peptide-MHC ligands regulates T-cell receptor signaling., Nadia Anikeeva, Dimitry Gakamsky, Jørgen Schøller, and Yuri Sykulev

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Changes in serum Interleukin-33 concentration before and after treatment with pegylated interferon alfa-2a plus ribavirin in patients with chronic hepatitis C genotype 1b infection., Bruno Cacopardo, Marilia Rita Pinzone, Filippo Palermo, and Giuseppe Nunnari

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Immune clearance of attenuated rabies virus results in neuronal survival with altered gene expression., Emily A Gomme, Christoph Wirblich, Sankar Addya, Glenn F Rall, and Matthias J Schnell

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Effects of apoptotic cell accumulation caused by Mer deficiency on germinal center B cells and helper T cells, Tahsin N. Khan, Eric B. Wong, and Ziaur S.M. Rahman

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Microbial translocation in chronic liver diseases., Marilia Rita Pinzone, Benedetto Maurizio Celesia, Michele Di Rosa, Bruno Cacopardo, and Giuseppe Nunnari

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HIV RNA suppression and immune restoration: can we do better?, Marilia Rita Pinzone, Michelino Di Rosa, Bruno Cacopardo, and Giuseppe Nunnari

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A Novel Function for SNAP29 (Synaptosomal-Associated Protein of 29 kDa) in Mast Cell Phagocytosis., Jordan Wesolowski, Vernon Caldwell, and Fabienne Paumet

Manuscripts from 2011

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Immunization with the recombinant antigen Ss-IR induces protective immunity to infection with Strongyloides stercoralis in mice., David Abraham, Jessica A. Hess, Rojelio Mejia, Thomas J. Nolan, James B. Lok, Sara Lustigman, and Thomas B. Nutman

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Innate and adaptive immunity to the nematode Strongyloides stercoralis in a mouse model., Sandra Bonne-Annee, Jessica A. Hess, and David Abraham

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Macrophages and neutrophils from humans and mice kill larval Strongyloides stercoralis during innate immunity, Sandra Bonne-Annee; Laura A. Kerepesi; Jessica A. Hess Ligas; and David Abraham, PhD

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RIP1-dependent and independent effects of necrostatin-1 in necrosis and T cell activation., YoungSik Cho, Thomas McQuade, Haibing Zhang, Jianke Zhang, and Francis Ka-Ming Chan

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B1b lymphocyte-derived antibodies control Borrelia hermsii independent of Fcα/μ receptor and in the absence of host cell contact., Matthew J. Colombo, David Abraham, Akira Shibuya, and Kishore R. Alugupalli

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Functional Macroautophagy Induction by Influenza A Virus without a Contribution to Major Histocompatibility Complex Class II-Restricted Presentation., Joseph D Comber, Tara M Robinson, Nicholas A Siciliano, Adam E Snook, and Laurence C Eisenlohr

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A conserved tissue-specific homeodomain-less isoform of MEIS1 is downregulated in colorectal cancer., Richard C Crist, Jacquelyn J Roth, Scott A Waldman, and Arthur M Buchberg

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Hydrophobicity as a driver of MHC class I antigen processing., Lan Huang, Matthew C Kuhls, and Laurence C. Eisenlohr

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Comparison of human memory CD8 T cell responses to adenoviral early and late proteins in peripheral blood and lymphoid tissue., Amita Joshi, Biwei Zhao, Cara Romanowski, David Rosen, and Phyllis Flomenberg

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Technical approaches for mouse models of human disease., Monica J Justice, Linda D. Siracusa, and A Francis Stewart

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The Role of Mer in Apoptotic Cell Clearance in the Germinal Center, Tahsin N. Khan; Eric B. Wong; and Ziaur S.M. Rahman, PhD

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CNS recruitment of CD8+ T lymphocytes specific for a peripheral virus infection triggers neuropathogenesis during polymicrobial challenge., Christine M Matullo, Kevin J O'Regan, Mark Curtis, and Glenn F Rall

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The RET/PTC3 oncogene activates classical NF-κB by stabilizing NIK., R J Neely, M S Brose, C M Gray, K A McCorkell, J M Leibowitz, C Ma, J L Rothstein, and M J May

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Soluble extract from the nematode Strongyloides stercoralis induces CXCR2 dependent/IL-17 independent neutrophil recruitment., Amy E. O'Connell, Kevin Redding, Jessica A. Hess, James B. Lok, Thomas J. Nolan, and David Abraham

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Microarray-based analysis of differential gene expression between infective and noninfective larvae of Strongyloides stercoralis., Roshan Ramanathan, Sudhir Varma, José M C Ribeiro, Timothy G Myers, Thomas J Nolan, David Abraham, James B Lok, and Thomas B Nutman

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Buffered memory: a hypothesis for the maintenance of functional, virus-specific CD8(+) T cells during cytomegalovirus infection., Christopher M Snyder

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Sustained CD8+ T cell memory inflation after infection with a single-cycle cytomegalovirus., Christopher M Snyder, Kathy S Cho, Elizabeth L Bonnett, Jane E Allan, and Ann B Hill

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The characteristics of Borrelia hermsii infection in human hematopoeitic stem cell-engrafted mice mirror those of human relapsing fever, Raja Vuyyuru, Hongqi Liu, Tim Manser, and Kishore Alugupalli

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Functional complementation between FADD and RIP1 in embryos and lymphocytes., Haibing Zhang, Xiaohui Zhou, Thomas McQuade, Jinghe Li, Francis Ka-Ming Chan, and Jianke Zhang

Manuscripts from 2010

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Rabies virus infection induces type I interferon production in an IPS-1 dependent manner while dendritic cell activation relies on IFNAR signaling., Elizabeth J Faul, Celestine N Wanjalla, Mehul S Suthar, Michael Gale, Christoph Wirblich, and Matthias J Schnell

Manuscripts from 2009

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Interferon response and viral evasion by members of the family rhabdoviridae., Elizabeth J Faul, Douglas S Lyles, and Matthias J. Schnell

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Development of a mouse monoclonal antibody cocktail for post-exposure rabies prophylaxis in humans., Thomas Müller, Bernhard Dietzschold, Hildegund Ertl, Anthony R Fooks, Conrad Freuling, Christine Fehlner-Gardiner, Jeannette Kliemt, Francois X Meslin, Charles E Rupprecht, Noël Tordo, Alexander I Wanderler, and Marie Paule Kieny

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IL-4(-/-) mice with lethal Mesocestoides corti infections--reduced Th2 cytokines and alternatively activated macrophages., A. E. O'Connell, L. A. Kerepesi, G. L. Vandergrift, D. R. Herbert, T J. VAN Winkle, D. C. Hooper, E J. Pearce, and D. Abraham

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Intracellular bacteria encode inhibitory SNARE-like proteins., Fabienne Paumet, Jordan Wesolowski, Alejandro Garcia-Diaz, Cedric Delevoye, Nathalie Aulner, Howard A Shuman, Agathe Subtil, and James E Rothman

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Intravenous inoculation of a bat-associated rabies virus causes lethal encephalopathy in mice through invasion of the brain via neurosecretory hypothalamic fibers., Mirjam A R Preuss, Marie-Luise Faber, Gene S Tan, Michael Bette, Bernhard Dietzschold, Eberhard Weihe, and Matthias J Schnell

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Germinal center reutilization by newly activated B cells., Tanja A Schwickert, Boris Alabyev, Tim Manser, and Michel C Nussenzweig

Manuscripts from 2008

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A distinct role for B1b lymphocytes in T cell-independent immunity, Kishore R. Alugupalli

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Inhibition of oncogene-induced inflammatory chemokines using a farnesyltransferase inhibitor., Katharine C Degeorge, Brent R Degeorge, James S Testa, and Jay L Rothstein

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The cytoplasmic tail of the rabies virus G protein is an essential domain controlling death/survival in human neuronal cells, Christophe Prehaud, Mireille Lafage, Gene S. Tan, Françoise Mégret, Pauline Ménager, Matthias Schnell, Henri Buc, and Monique Lafon

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Intravenous inoculation of silver-haired bat rabies virus, but not of a canine strain, elicits lethal encephalophathy in mice by fast brain invasion via neurosecretory hypothalamic fibers, Mirjam AR Preuss, Marie-Luise Faber, Gene S. Tan, Bernhard Dietzschold, Matthias J. Schnell, and Eberhard Weihe

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A comprehensive analysis of the naturally occurring polymorphisms in HIV-1 Vpr: potential impact on CTL epitopes., Alagarsamy Srinivasan, Velpandi Ayyavoo, Sundarasamy Mahalingam, Aarthi Kannan, Anne Boyd, Debduti Datta, Vaniambadi S Kalyanaraman, Anthony Cristillo, Ronald G Collman, Nelly Morellet, Bassel E Sawaya, and Ramachandran Murali

Manuscripts from 2007

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Signaling through Galphai2 protein is required for recruitment of neutrophils for antibody-mediated elimination of larval Strongyloides stercoralis in mice., Udaikumar M. Padigel, Louis Stein, Kevin Redding, James J. Lee, Thomas J. Nolan, Gerhard A. Schad, Lutz Birnbaumer, and David Abraham

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Expression of the autoimmune Fcgr2b NZW allele fails to be upregulated in germinal center B cells and is associated with increased IgG production, S.M. Ziaur Rahman, H. Niu, D. Perry, Timothy L. Manser, and L. Morel

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MicroRNA genes are frequently located near mouse cancer susceptibility loci., Cinzia Sevignani, George A. Calin, Stephanie C. Nnadi, Masayoshi Shimizu, Ramana V. Davuluri, Terry Hyslop, Peter Demant, Carlo M. Croce, and Linda D. Siracusa

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The activity of azithromycin against Leishmania (Viannia) braziliensis and Leishmania (Leishmania) amazonensis in the golden hamster model., Angel Sinagra, Concepción Luna, David Abraham, Maria del Carmen Iannella, Adelina Riarte, and Alejandro J. Krolewiecki

Manuscripts from 2005

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Global gene expression profiling of cells overexpressing SMC3., Giancarlo Ghiselli and Chang-Gong Liu

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Orally Delivered, Plant-Produced Tat Protein Primes Mice For a Challenge DNA Vaccine Expressing Tat, A V. Karasev, S Foulke, C Wellens, I Zwierzynski, R Baldwin, H Koprowski, and M S. Reitz Jr

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Mammalian microRNAs: A small world for fine-tuning gene expression, Cinzia Sevignani, George A. Calin, Linda D. Siracusa, and Carlo M. Croce

Manuscripts from 2002

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G protein-coupled receptor/arrestin3 modulation of the endocytic machinery., Francesca Santini, Ibragim Gaidarov, and James H Keen

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Characterization of subcellular localization and stability of a splice variant of G alpha i2., Philip B Wedegaertner

Manuscripts from 2001

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Proteolytic release of CD44 intracellular domain and its role in the CD44 signaling pathway., I Okamoto, Y Kawano, D Murakami, T Sasayama, N Araki, T Miki, A J Wong, and H Saya

Manuscripts from 1999

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Phosphoinositide-AP-2 interactions required for targeting to plasma membrane clathrin-coated pits., I Gaidarov and James H. Keen

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Signal transducer and activator of transcription (STAT)5 activation by BCR/ABL is dependent on intact Src homology (SH)3 and SH2 domains of BCR/ABL and is required for leukemogenesis., M Nieborowska-Skorska, M A Wasik, A Slupianek, P Salomoni, T Kitamura, B Calabretta, and T Skorski

Manuscripts from 1998

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The baculovirus anti-apoptotic p35 protein promotes transformation of mouse embryo fibroblasts., M Resnicoff, B. Valentinis, D. Herbert, D. Abraham, P D. Friesen, E. S. Alnemri, and R Baserga

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Expression of constitutively active Raf-1 in the mitochondria restores antiapoptotic and leukemogenic potential of a transformation-deficient BCR/ABL mutant., P Salomoni, M A Wasik, R F Riedel, K Reiss, J K Choi, T Skorski, and B Calabretta

Manuscripts from 1997

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Chronicity in Strongyloides stercoralis infections: dichotomy of the protective immune response to infective and autoinfective larvae in a mouse model., R. A. Brigandi, H. L. Rotman, T. J. Nolan, G. A. Schad, and D. Abraham

Manuscripts from 1993

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Induction of protective immunity against larval Onchocerca volvulus in a mouse model., A. M. Lange, W. Yutanawiboonchai, J. B. Lok, M. Trpis, and D. Abraham

Manuscripts from 1989

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Immunity to larval Brugia malayi in BALB/c mice: protective immunity and inhibition of larval development., D. Abraham, R. B. Grieve, J. M. Holy, and B. M. Christensen