Manuscripts from 2015
The Onchocerciasis Vaccine for Africa-TOVA-Initiative., Peter J Hotez, Maria Elena Bottazzi, Bin Zhan, Benjamin L Makepeace, Thomas R Klei, David Abraham, David W Taylor, and Sara Lustigman
Rhabdovirus-based vaccine platforms against henipaviruses., Drishya Kurup, Christoph Wirblich, Heinz Feldmann, Andrea Marzi, and Matthias J. Schnell
Lymph node but not intradermal injection site macrophages are critical for germinal center formation and antibody responses to rabies vaccination., Andrew G Lytle, Shixue Shen, and James McGettigan
Endogenous antigen processing drives the primary CD4+ T cell response to influenza., Michael A Miller, Asha Purnima V Ganesan, Nancy Luckashenak, Mark Mendonca, and Laurence C. Eisenlohr
Reverse genetics of Mononegavirales: How they work, new vaccines, and new cancer therapeutics., Christian K Pfaller, Roberto Cattaneo, and Matthias J. Schnell
Memory T Cells Specific for Murine Cytomegalovirus Re-Emerge after Multiple Challenges and Recapitulate Immunity in Various Adoptive Transfer Scenarios., Michael Quinn, Holly Turula, Mayank Tandon, Berthony Deslouches, Toktam Moghbeli, and Christopher M. Snyder
Murine CMV Infection Induces the Continuous Production of Mucosal Resident T Cells., Corinne J Smith, Sofia Caldeira-Dantas, Holly Turula, and Christopher M. Snyder
Manuscripts from 2014
Core-based lipid nanoparticles as a nanoplatform for delivery of near-infrared fluorescent imaging agents., Nadia Anikeeva, Yuri Sykulev, Edward J Delikatny, and Anatoliy V Popov
Vaccination with a genetically modified Brugia malayi cysteine protease inhibitor-2 reduces adult parasite numbers and affects the fertility of female worms following a subcutaneous challenge of Mongolian gerbils (Meriones unguiculatus) with B. malayi infective larvae., Sridhar Arumugam, Junfei Wei, Danielle Ward, David Abraham, Sara Lustigman, Bin Zhan, and Thomas R. Klei
Vaccination with recombinant Brugia malayi cystatin proteins alters worm migration, homing and final niche selection following a subcutaneous challenge of Mongolian gerbils (Meriones unguiculatus) with B. malayi infective larvae., Sridhar Arumugam, Bin Zhan, David Abraham, Danielle Ward, Sara Lustigman, and Thomas R Klei
Extracellular traps are associated with human and mouse neutrophil and macrophage mediated killing of larval Strongyloides stercoralis., Sandra Bonne-Annee, Laura A. Kerepesi, Jessica A. Hess, Jordan Wesolowski, Fabienne Paumet, James B. Lok, Thomas J. Nolan, and David Abraham
MyD88-Dependent Immunity to a Natural Model of Vaccinia Virus Infection Does Not Involve Toll-Like Receptor 2., Michael L Davies, Janet J Sei, Nicholas A Siciliano, Ren-Huan Xu, Felicia Roscoe, Luis J Sigal, Laurence C. Eisenlohr, and Christopher C Norbury
Efficient B cell responses to Borrelia hermsii infection depend on BAFF and BAFFR but not TACI., Gregory S. Dickinson, PhD; Guizhi Sun; Richard J Bram; and Kishore Alugupalli
Interleukin-7-dependent B lymphocytes are required for the anti-pneumococcal polysaccharide response and protective immunity to Streptococcus pneumoniae, Gregory S. Dickinson, PhD; Raja Vuyyuru; Timothy L. Manser, PhD; John F. Kerney; and Kishore Alugupalli, PhD
Small-Molecule Probes Targeting the Viral PPxY-Host Nedd4 Interface Block Egress of a Broad Range of RNA Viruses., Ziying Han, Jianhong Lu, Yuliang Liu, Benjamin Davis, Michael S Lee, Mark A Olson, Gordon Ruthel, Bruce D Freedman, Matthias J. Schnell, Jay E Wrobel, Allen B Reitz, and Ronald N Harty
Epithelial Immunization Induces Polyfunctional CD8+ T Cells and Optimal Mousepox Protection., Adam R Hersperger, Nicholas A Siciliano, Brian C DeHaven, Adam E. Snook, and Laurence C. Eisenlohr
Vaccines to combat river blindness: expression, selection and formulation of vaccines against infection with Onchocerca volvulus in a mouse model., Jessica A. Hess, Bin Zhan, Sandra Bonne-Annee, Jessica M. Deckman, Maria Elena Bottazzi, Peter J. Hotez, Thomas R R. Klei, Sara Lustigman, and David Abraham
Characterization of T-bet and eomes in peripheral human immune cells., James J. Knox, Gabriela L. Cosma, Michael R. Betts, and Laura M. McLane
ICAM-1-Based Rabies Virus Vaccine Shows Increased Infection and Activation of Primary Murine B Cells In Vitro and Enhanced Antibody Titers In-Vivo., James E Norton, Andrew G Lytle, Shixue Shen, Evgeni P Tzvetkov, Corin L Dorfmeier, and James P McGettigan
IDO2 in Immunomodulation and Autoimmune Disease., George C Prendergast, Richard Metz, Alexander J Muller, Lauren M F Merlo, and Laura Mandik-Nayak
CD27high/KLRG1low CD8+ T cells that persist throughout MCMV infection are highly expansive and have the ability to reestablish MCMV immunity, Michael Quinn, Holly Turula, and Christopher M. Snyder
Limited Brain Metabolism Changes Differentiate between the Progression and Clearance of Rabies Virus., Keith Schutsky, Carla Portocarrero, D Craig Hooper, Bernhard Dietzschold, and Milosz Faber
Impact of distinct poxvirus infections on the specificities and functionalities of CD4+ T cell responses., Nicholas A Siciliano, Adam R Hersperger, Aimee M Lacuanan, Ren-Huan Xu, John Sidney, Alessandro Sette, Luis J Sigal, and Laurence C. Eisenlohr
Systemic hematogenous maintenance of memory inflation by MCMV infection., Corinne J Smith, Holly Turula, and Christopher M. Snyder
Monitoring Cancer Therapy by mRNA PET Imaging, Eric Wickstrom
Resolving the titer of murine cytomegalovirus by plaque assay using the M2-10B4 cell line and a low viscosity overlay., Katherine A Zurbach, Toktam Moghbeli, and Christopher M Snyder
Manuscripts from 2013
Antibody quality and protection from lethal ebola virus challenge in nonhuman primates immunized with rabies virus based bivalent vaccine., Joseph E Blaney, Andrea Marzi, Mallory Willet, Amy B Papaneri, Christoph Wirblich, Friederike Feldmann, Michael Holbrook, Peter Jahrling, Heinz Feldmann, and Matthias J Schnell
Isolated laryngeal leishmaniasis in immunocompetent patients: an underdiagnosed disease., Salvatore Cocuzza, Alessio Strazzulla, Marilia Rita Pinzone, Stefano Cosentino, Agostino Serra, Rosario Caltabiano, Salvatore Lanzafame, Bruno Cacopardo, and Giuseppe Nunnari
Investigating the role for IL-21 in rabies virus vaccine-induced immunity., Corin L Dorfmeier, Evgeni P Tzvetkov, Anthony Gatt, and James P McGettigan
Competition for antigen at the level of the APC is a major determinant of immunodominance during memory inflation in murine cytomegalovirus infection., Lila A Farrington, Tameka A Smith, Finn Grey, Ann B Hill, and Christopher M. Snyder
Snapin, Positive Regulator of Stimulation- Induced Ca(2+) Release through RyR, Is Necessary for HIV-1 Replication in T Cells., Shigemi M Kinoshita, Amane Kogure, Shizuka Taguchi, and Garry P Nolan
A public health response against Strongyloides stercoralis: time to look at soil-transmitted helminthiasis in full., Alejandro J Krolewiecki, Patrick Lammie, Julie Jacobson, Albis-Francesco Gabrielli, Bruno Levecke, Eugenia Socias, Luis M Arias, Nicanor Sosa, David Abraham, Ruben Cimino, Adriana Echazú, Favio Crudo, Jozef Vercruysse, and Marco Albonico
Comparison of Heterologous Prime-Boost Strategies against Human Immunodeficiency Virus Type 1 Gag Using Negative Stranded RNA Viruses., Tessa M Lawrence, Celestine N Wanjalla, Emily A Gomme, Christoph Wirblich, Anthony Gatt, Elena Carnero, Adolfo García-Sastre, Douglas S Lyles, James P McGettigan, and Matthias J Schnell
Collagen Content in Skin and Internal Organs of the Tight Skin Mouse: An Animal Model of Scleroderma., Jayanthi Manne, Marina Markova, Linda D Siracusa, and Sergio A Jimenez
Toward a Network Model of MHC Class II-Restricted Antigen Processing., Michael A Miller, Asha Purnima V Ganesan, and Laurence C. Eisenlohr
Two coiled-coil domains of Chlamydia trachomatis IncA affect membrane fusion events during infection., Erik Ronzone and Fabienne Paumet
Competition for antigen selects T cell responses that undergo memory inflation and maintains clonal dominance during MCMV infection, Holly Turula, Lila A. Farrington, Corinne Smith, Ann B. Hill, and Christopher M Snyder
Manuscripts from 2012
Evidence that the density of self peptide-MHC ligands regulates T-cell receptor signaling., Nadia Anikeeva, Dimitry Gakamsky, Jørgen Schøller, and Yuri Sykulev
Changes in serum Interleukin-33 concentration before and after treatment with pegylated interferon alfa-2a plus ribavirin in patients with chronic hepatitis C genotype 1b infection., Bruno Cacopardo, Marilia Rita Pinzone, Filippo Palermo, and Giuseppe Nunnari
Immune clearance of attenuated rabies virus results in neuronal survival with altered gene expression., Emily A Gomme, Christoph Wirblich, Sankar Addya, Glenn F Rall, and Matthias J Schnell
Effects of apoptotic cell accumulation caused by Mer deficiency on germinal center B cells and helper T cells, Tahsin N. Khan, Eric B. Wong, and Ziaur S.M. Rahman
Microbial translocation in chronic liver diseases., Marilia Rita Pinzone, Benedetto Maurizio Celesia, Michele Di Rosa, Bruno Cacopardo, and Giuseppe Nunnari
HIV RNA suppression and immune restoration: can we do better?, Marilia Rita Pinzone, Michelino Di Rosa, Bruno Cacopardo, and Giuseppe Nunnari
A Novel Function for SNAP29 (Synaptosomal-Associated Protein of 29 kDa) in Mast Cell Phagocytosis., Jordan Wesolowski, Vernon Caldwell, and Fabienne Paumet
Manuscripts from 2011
Immunization with the recombinant antigen Ss-IR induces protective immunity to infection with Strongyloides stercoralis in mice., David Abraham, Jessica A. Hess, Rojelio Mejia, Thomas J. Nolan, James B. Lok, Sara Lustigman, and Thomas B. Nutman
Innate and adaptive immunity to the nematode Strongyloides stercoralis in a mouse model., Sandra Bonne-Annee, Jessica A. Hess, and David Abraham
Macrophages and neutrophils from humans and mice kill larval Strongyloides stercoralis during innate immunity, Sandra Bonne-Annee; Laura A. Kerepesi; Jessica A. Hess Ligas; and David Abraham, PhD
RIP1-dependent and independent effects of necrostatin-1 in necrosis and T cell activation., YoungSik Cho, Thomas McQuade, Haibing Zhang, Jianke Zhang, and Francis Ka-Ming Chan
B1b lymphocyte-derived antibodies control Borrelia hermsii independent of Fcα/μ receptor and in the absence of host cell contact., Matthew J. Colombo, David Abraham, Akira Shibuya, and Kishore R. Alugupalli
Functional Macroautophagy Induction by Influenza A Virus without a Contribution to Major Histocompatibility Complex Class II-Restricted Presentation., Joseph D Comber, Tara M Robinson, Nicholas A Siciliano, Adam E Snook, and Laurence C Eisenlohr
A conserved tissue-specific homeodomain-less isoform of MEIS1 is downregulated in colorectal cancer., Richard C Crist, Jacquelyn J Roth, Scott A Waldman, and Arthur M Buchberg
Hydrophobicity as a driver of MHC class I antigen processing., Lan Huang, Matthew C Kuhls, and Laurence C. Eisenlohr
Comparison of human memory CD8 T cell responses to adenoviral early and late proteins in peripheral blood and lymphoid tissue., Amita Joshi, Biwei Zhao, Cara Romanowski, David Rosen, and Phyllis Flomenberg
Technical approaches for mouse models of human disease., Monica J Justice, Linda D. Siracusa, and A Francis Stewart
The Role of Mer in Apoptotic Cell Clearance in the Germinal Center, Tahsin N. Khan; Eric B. Wong; and Ziaur S.M. Rahman, PhD
CNS recruitment of CD8+ T lymphocytes specific for a peripheral virus infection triggers neuropathogenesis during polymicrobial challenge., Christine M Matullo, Kevin J O'Regan, Mark Curtis, and Glenn F Rall
The RET/PTC3 oncogene activates classical NF-κB by stabilizing NIK., R J Neely, M S Brose, C M Gray, K A McCorkell, J M Leibowitz, C Ma, J L Rothstein, and M J May
Soluble extract from the nematode Strongyloides stercoralis induces CXCR2 dependent/IL-17 independent neutrophil recruitment., Amy E. O'Connell, Kevin Redding, Jessica A. Hess, James B. Lok, Thomas J. Nolan, and David Abraham
Microarray-based analysis of differential gene expression between infective and noninfective larvae of Strongyloides stercoralis., Roshan Ramanathan, Sudhir Varma, José M C Ribeiro, Timothy G Myers, Thomas J Nolan, David Abraham, James B Lok, and Thomas B Nutman
Buffered memory: a hypothesis for the maintenance of functional, virus-specific CD8(+) T cells during cytomegalovirus infection., Christopher M Snyder
Sustained CD8+ T cell memory inflation after infection with a single-cycle cytomegalovirus., Christopher M Snyder, Kathy S Cho, Elizabeth L Bonnett, Jane E Allan, and Ann B Hill
The characteristics of Borrelia hermsii infection in human hematopoeitic stem cell-engrafted mice mirror those of human relapsing fever, Raja Vuyyuru, Hongqi Liu, Tim Manser, and Kishore Alugupalli
Functional complementation between FADD and RIP1 in embryos and lymphocytes., Haibing Zhang, Xiaohui Zhou, Thomas McQuade, Jinghe Li, Francis Ka-Ming Chan, and Jianke Zhang
Manuscripts from 2010
Rabies virus infection induces type I interferon production in an IPS-1 dependent manner while dendritic cell activation relies on IFNAR signaling., Elizabeth J Faul, Celestine N Wanjalla, Mehul S Suthar, Michael Gale, Christoph Wirblich, and Matthias J Schnell
Manuscripts from 2009
Interferon response and viral evasion by members of the family rhabdoviridae., Elizabeth J Faul, Douglas S Lyles, and Matthias J. Schnell
Development of a mouse monoclonal antibody cocktail for post-exposure rabies prophylaxis in humans., Thomas Müller, Bernhard Dietzschold, Hildegund Ertl, Anthony R Fooks, Conrad Freuling, Christine Fehlner-Gardiner, Jeannette Kliemt, Francois X Meslin, Charles E Rupprecht, Noël Tordo, Alexander I Wanderler, and Marie Paule Kieny
IL-4(-/-) mice with lethal Mesocestoides corti infections--reduced Th2 cytokines and alternatively activated macrophages., A. E. O'Connell, L. A. Kerepesi, G. L. Vandergrift, D. R. Herbert, T J. VAN Winkle, D. C. Hooper, E J. Pearce, and D. Abraham
Intracellular bacteria encode inhibitory SNARE-like proteins., Fabienne Paumet, Jordan Wesolowski, Alejandro Garcia-Diaz, Cedric Delevoye, Nathalie Aulner, Howard A Shuman, Agathe Subtil, and James E Rothman
Intravenous inoculation of a bat-associated rabies virus causes lethal encephalopathy in mice through invasion of the brain via neurosecretory hypothalamic fibers., Mirjam A R Preuss, Marie-Luise Faber, Gene S Tan, Michael Bette, Bernhard Dietzschold, Eberhard Weihe, and Matthias J Schnell
Germinal center reutilization by newly activated B cells., Tanja A Schwickert, Boris Alabyev, Tim Manser, and Michel C Nussenzweig
Manuscripts from 2008
A distinct role for B1b lymphocytes in T cell-independent immunity, Kishore R. Alugupalli
Inhibition of oncogene-induced inflammatory chemokines using a farnesyltransferase inhibitor., Katharine C Degeorge, Brent R Degeorge, James S Testa, and Jay L Rothstein
The cytoplasmic tail of the rabies virus G protein is an essential domain controlling death/survival in human neuronal cells, Christophe Prehaud, Mireille Lafage, Gene S. Tan, Françoise Mégret, Pauline Ménager, Matthias Schnell, Henri Buc, and Monique Lafon
Intravenous inoculation of silver-haired bat rabies virus, but not of a canine strain, elicits lethal encephalophathy in mice by fast brain invasion via neurosecretory hypothalamic fibers, Mirjam AR Preuss, Marie-Luise Faber, Gene S. Tan, Bernhard Dietzschold, Matthias J. Schnell, and Eberhard Weihe
A comprehensive analysis of the naturally occurring polymorphisms in HIV-1 Vpr: potential impact on CTL epitopes., Alagarsamy Srinivasan, Velpandi Ayyavoo, Sundarasamy Mahalingam, Aarthi Kannan, Anne Boyd, Debduti Datta, Vaniambadi S Kalyanaraman, Anthony Cristillo, Ronald G Collman, Nelly Morellet, Bassel E Sawaya, and Ramachandran Murali
Manuscripts from 2007
Signaling through Galphai2 protein is required for recruitment of neutrophils for antibody-mediated elimination of larval Strongyloides stercoralis in mice., Udaikumar M. Padigel, Louis Stein, Kevin Redding, James J. Lee, Thomas J. Nolan, Gerhard A. Schad, Lutz Birnbaumer, and David Abraham
Expression of the autoimmune Fcgr2b NZW allele fails to be upregulated in germinal center B cells and is associated with increased IgG production, S.M. Ziaur Rahman, H. Niu, D. Perry, Timothy L. Manser, and L. Morel
MicroRNA genes are frequently located near mouse cancer susceptibility loci., Cinzia Sevignani, George A. Calin, Stephanie C. Nnadi, Masayoshi Shimizu, Ramana V. Davuluri, Terry Hyslop, Peter Demant, Carlo M. Croce, and Linda D. Siracusa
The activity of azithromycin against Leishmania (Viannia) braziliensis and Leishmania (Leishmania) amazonensis in the golden hamster model., Angel Sinagra, Concepción Luna, David Abraham, Maria del Carmen Iannella, Adelina Riarte, and Alejandro J. Krolewiecki
Manuscripts from 2005
Global gene expression profiling of cells overexpressing SMC3., Giancarlo Ghiselli and Chang-Gong Liu
Orally Delivered, Plant-Produced Tat Protein Primes Mice For a Challenge DNA Vaccine Expressing Tat, A V. Karasev, S Foulke, C Wellens, I Zwierzynski, R Baldwin, H Koprowski, and M S. Reitz Jr
Mammalian microRNAs: A small world for fine-tuning gene expression, Cinzia Sevignani, George A. Calin, Linda D. Siracusa, and Carlo M. Croce
Manuscripts from 2002
G protein-coupled receptor/arrestin3 modulation of the endocytic machinery., Francesca Santini, Ibragim Gaidarov, and James H Keen
Characterization of subcellular localization and stability of a splice variant of G alpha i2., Philip B Wedegaertner
Manuscripts from 2001
Proteolytic release of CD44 intracellular domain and its role in the CD44 signaling pathway., I Okamoto, Y Kawano, D Murakami, T Sasayama, N Araki, T Miki, A J Wong, and H Saya
Manuscripts from 1999
Phosphoinositide-AP-2 interactions required for targeting to plasma membrane clathrin-coated pits., I Gaidarov and James H. Keen
Signal transducer and activator of transcription (STAT)5 activation by BCR/ABL is dependent on intact Src homology (SH)3 and SH2 domains of BCR/ABL and is required for leukemogenesis., M Nieborowska-Skorska, M A Wasik, A Slupianek, P Salomoni, T Kitamura, B Calabretta, and T Skorski
Manuscripts from 1998
The baculovirus anti-apoptotic p35 protein promotes transformation of mouse embryo fibroblasts., M Resnicoff, B. Valentinis, D. Herbert, D. Abraham, P D. Friesen, E. S. Alnemri, and R Baserga
Expression of constitutively active Raf-1 in the mitochondria restores antiapoptotic and leukemogenic potential of a transformation-deficient BCR/ABL mutant., P Salomoni, M A Wasik, R F Riedel, K Reiss, J K Choi, T Skorski, and B Calabretta
Manuscripts from 1997
Chronicity in Strongyloides stercoralis infections: dichotomy of the protective immune response to infective and autoinfective larvae in a mouse model., R. A. Brigandi, H. L. Rotman, T. J. Nolan, G. A. Schad, and D. Abraham
Manuscripts from 1993
Induction of protective immunity against larval Onchocerca volvulus in a mouse model., A. M. Lange, W. Yutanawiboonchai, J. B. Lok, M. Trpis, and D. Abraham
Manuscripts from 1989
Immunity to larval Brugia malayi in BALB/c mice: protective immunity and inhibition of larval development., D. Abraham, R. B. Grieve, J. M. Holy, and B. M. Christensen
