Submissions from 2024
GUCY2C Signaling Limits Dopaminergic Neuron Vulnerability to Toxic Insults, Lara Cheslow, Matthew Byrne, Jessica Kopenhaver, Lorraine Iacovitti, Richard Smeyne, Adam Snook, and Scott Waldman
The Nuclear Import Receptor Kapβ2 Modifies Neurotoxicity Mediated by Poly(GR) in C9orf72-linked ALS/FTD, Maria Elena Cicardi, V. Kankate, Sindhu Sriramoji, Karthik Krishnamurthy, S. S. Markandaiah, B. M. Verdone, Amandeep Girdhar, A. Nelson, L. B. Rivas, A. Boehringer, Aaron R. Haeusler, Piera Pasinelli, Lin Guo, and Davide Trotti
Multiple Guidance Mechanisms Control Axon Growth to Generate Precise T-Shaped Bifurcation During Dorsal Funiculus Development in the Spinal Cord, Bridget M. Curran, Kelsey R. Nickerson, Andrea R. Yung, Lisa V. Goodrich, Alexander Jaworski, Marc Tessier-Lavigne, and Le Ma
Recovery After Human Bone Marrow Mesenchymal Stem Cells (hBM-MCs)-Derived Extracellular Vesicles (EVs) Treatment in Post-MCAO Rats Requires Repeated Handling, Yolanda Gomez-Galvez, Malvika Gupta, Mandeep Kaur, Salvatore Fusco, Maria Vittoria Podda, Claudio Grassi, Amit K. Srivastava, Lorraine Iacovitti, and Elena Blanco-Suarez
The Binding and Mechanism of a Positive Allosteric Modulator of Kv3 Channels, Qiansheng Liang, Gamma Chi, Leonardo Cirqueira, Lianteng Zhi, Agostino Marasco, Nadia Pilati, Martin Gunthorpe, Giuseppe Alvaro, Charles Large, David Sauer, Werner Treptow, and Manuel Covarrubias
Shared and Distinct Cortical Morphometric Alterations in Five Neuropsychiatric Symptoms of Parkinson’s Disease, Qianling Lu, Zhuang Zhu, Heng Zhang, Caiting Gan, Aidi Shan, Mengxi Gao, Huimin Sun, Xingyue Cao, Yongsheng Yuan, Joseph I Tracy, Qirui Zhang, and Kezhong Zhang
Exploring Functional Connectivity in Chronic Spinal Cord Injury Patients With Neuropathic Pain Versus Without Neuropathic Pain, Shreya Mandloi, Mashaal Syed, Isaiah Ailes, Omid Shoraka, Benjamin Leiby, J. Miao, Sara Thalheimer, Joshua Pelta-Heller, Feroze Mohamed, Ashwini Sharan, James Harrop, Laura Krisa, and M. Alizadeh
Submissions from 2023
SynLight: A Bicistronic Strategy for Simultaneous Active Zone and Cell Labeling in the Drosophila Nervous System, Michael A. Aimino, Jesse Humenik, Michael J. Parisi, Juan Carlos Duhart, and Timothy J. Mosca
Loss of PML Nuclear Bodies in Familial Amyotrophic Lateral Sclerosis-Frontotemporal Dementia, Francesco Antoniani, Marco Cimino, Laura Mediani, Jonathan Vinet, Enza M. Verde, Valentina Secco, Alfred Yamoah, Priyanka Tripathi, Eleonora Aronica, Maria Elena Cicardi, Davide Trotti, Jared Sterneckert, Anand Goswami, and Serena Carra
C9orf72 Poly(PR) Mediated Neurodegeneration Is Associated With Nucleolar Stress, M. E. Cicardi, J. H. Hallgren, D. Mawrie, K. Krishnamurthy, S. S. Markandaiah, A. T. Nelson, V. Kankate, E. N. Anderson, P. Pasinelli, U. B. Pandey, C. M. Eischen, and D. Trotti
Absence of Chordin-like 1 Aids Motor Recovery in a Mouse Model of Stroke, Eileen Collyer, Bridget R Boyle, Yolanda Gomez-Galvez, Lorraine Iacovitti, and Elena Blanco-Suarez
Racial Disparities in Access to DBS: Results of a Real-World U.S. Claims Data Analysis, Michael Frassica, Drew S Kern, Mitra Afshari, Allison T Connolly, Chengyuan Wu, Nathan Rowland, Juan Ramirez-Castaneda, Mwiza Ushe, Claudia Salazar, and Xenos Mason
Differential Response of C9orf72 Transcripts Following Neuronal Depolarization, Layla T. Ghaffari, Davide Trotti, and Aaron R. Haeusler
Advances in molecular pathology, diagnosis, and treatment of amyotrophic lateral sclerosis., Hristelina Ilieva, Mithila Vullaganti, and Justin Kwan
Sleep Problems in Old Age: Metabotropic Glutamate Receptor to the Rescue, Sho Inami, Dinis J.S. Afonso, and Kyunghee Koh
The Nurosleeve, a User-Centered 3D Printed Hybrid Orthosis for Individuals With Upper Extremity Impairment, Mehdi Khantan, Mikael Avery, Phyo Thuta Aung, Rachel M. Zarin, Emma Hammelef, Nabila Shawki, Mijail Demian Serruya, and Alessandro Naopli
Therapeutic Strategies Targeting Respiratory Recovery after Spinal Cord Injury: From Preclinical Development to Clinical Translation, Pauline Michel-Flutot, Michael A. Lane, Angelo C. Lepore, and Stéphane Vinit
A Conditional Strategy for Cell-Type-Specific Labeling of Endogenous Excitatory Synapses in Drosophila, Michael J. Parisi, Michael A. Aimino, and Timothy J. Mosca
Jun Upregulation Drives Aberrant Transposable Element Mobilization, Associated Innate Immune Response, and Impaired Neurogenesis in Alzheimer’s Disease, Chiara Scopa, Samantha Barnada, Maria Cicardi, Mo Singer, Davide Trotti, and Marco Trizzino
Submissions from 2022
Synaptic Development in Diverse Olfactory Neuron Classes Uses Distinct Temporal and Activity-Related Programs, Michael A. Aimino, Alison T. DePew, Lucas Restrepo, and Timothy J. Mosca
Response of Astrocyte Subpopulations Following Spinal Cord Injury., R Vivian Allahyari, Nicolette M Heinsinger, Daniel Hwang, David A Jaffe, Javad Rasouli, Stephanie Shiers, Samantha J Thomas, Theodore J Price, Abdolmohamad Rostami, and Angelo C Lepore
γ-Secretase promotes Drosophila Postsynaptic Development Through the Cleavage of a Wnt Receptor, Lucas J Restrepo, Alison T DePew, Elizabeth R Moese, Stephen R Tymanskyj, Michael J Parisi, Michael A Aimino, Juan Carlos Duhart, Hong Fei, and Timothy J Mosca
COVID-19 Infection Enhances Susceptibility to Oxidative Stress-Induced Parkinsonism., Richard Jay Smeyne, Jeffrey B Eells, Debotri Chatterjee, Matthew Byrne, Shaw M Akula, Srinivas Sriramula, Dorcas P O'Rourke, and Peter Schmidt
Editorial: Glia-Mediated Neurotoxicity: Uncovering the Molecular Mechanisms, Amit K Srivastava, Barbara Lukomska, and Lorraine Iacovitti
Submissions from 2021
Manganese exposure in juvenile C57BL/6 mice increases glial inflammatory responses in the substantia nigra following infection with H1N1 influenza virus., Collin M Bantle, C Tenley French, Jason E Cummings, Shankar Sadasivan, Kevin Tran, Richard A Slayden, Richard Jay Smeyne, and Ronald B Tjalkens
On the Road from Phenotypic Plasticity to Stem Cell Therapy., Lorraine Iacovitti
The effects of molecular crowding and CpG hypermethylation on DNA G-quadruplexes formed by the C9orf72 nucleotide repeat expansion., Kadir A. Ozcan, Layla T. Ghaffari, and Aaron R. Haeusler
Rapid Decline in Telestroke Consults in the Setting of COVID-19., Syed O. Shah., Robin Dharia, Jaime Stazi, Maureen DePrince, and Robert H. Rosenwasswer
Dynamic Network Connectivity Reveals Markers of Response to Deep Brain Stimulation in Parkinson’s Disease, Chengyuan Wu, Caio Matias, Thomas Foltynie, Patricia Limousin, Ludvic Zrinzo, and Harith Akram
Submissions from 2020
LAR inhibitory peptide promotes recovery of diaphragm function and multiple forms of respiratory neural circuit plasticity after cervical spinal cord injury., Lan Cheng, Armin Sami, Biswarup Ghosh, Mark W Urban, Nicolette M Heinsinger, Sophia S Liang, George M Smith, Megan C Wright, Shuxin Li, and Angelo C Lepore
Modulation of sleep-courtship balance by nutritional status in Drosophila, José M Duhart, Victoria Baccini, Yanan Zhang, Daniel R Machado, and Kyunghee Koh
Sleep Induction by Mechanosensory Stimulation in Drosophila., Arzu Öztürk-Çolak, Sho Inami, Joseph R. Buchler, Patrick D. McClanahan, Andri Cruz, Christopher Fang-Yen, and Kyunghee Koh
Submissions from 2019
MAP7 Prevents Axonal Branch Retraction by Creating a Stable Microtubule Boundary to Rescue Polymerization., Stephen R. Tymanskyj and Le Ma
Long-Distance Axon Regeneration Promotes Recovery of Diaphragmatic Respiratory Function after Spinal Cord Injury., Mark W. Urban, Biswarup Ghosh, Cole G. Block, Laura R. Strojny, Brittany A. Charsar, Miguel Goulão, Sreeya S. Komaravolu, George M. Smith, Megan C. Wright, Shuxin Li, and Angelo C. Lepore
Commentary: Using Directional Deep Brain Stimulation to Co-activate the Subthalamic Nucleus and Zona Incerta for Overlapping Essential Tremor/Parkinson's Disease Symptoms., Chengyuan Wu and Caio Matias
Submissions from 2018
Levels of Par-1 kinase determine the localization of Bruchpilot at the Drosophila neuromuscular junction synapses., Kara R. Barber, Martin Hruska, Keegan M. Bush, Jade A. Martinez, Hong Fei, Irwin B. Levitan, Matthew B. Dalva, and Yogesh P. Wairkar
Local BDNF Delivery to the Injured Cervical Spinal Cord using an Engineered Hydrogel Enhances Diaphragmatic Respiratory Function., Biswarup Ghosh, Zhicheng Wang, Jia Nong, Mark W. Urban, Zhiling Zhang, Victoria A. Trovillion, Megan C. Wright, Yinghui Zhong, and Angelo C. Lepore
miR126-5p Downregulation Facilitates Axon Degeneration and NMJ Disruption via a Non-Cell-Autonomous Mechanism in ALS., Roy Maimon, Ariel Ionescu, Avichai Bonnie, Sahar Sweetat, Shane Wald-Altman, Shani Inbar, Tal Gradus, Davide Trotti, Miguel Weil, Oded Behar, and Eran Perlson
Regulation of Nociceptive Glutamatergic Signaling by Presynaptic Kv3.4 Channels in the Rat Spinal Dorsal Horn., Tanziyah Muqeem, Biswarup Ghosh, Vitor Pinto, Angelo C. Lepore, and Manuel Covarrubias
Managing the Complex Patient with Degenerative Cervical Myelopathy: How to Handle the Aging Spine, the Obese Patient, and Individuals with Medical Comorbidities., Geoffrey Stricsek, John Gillick, George Rymarczuk, and James Harrop
Submissions from 2016
iPS cell transplantation for traumatic spinal cord injury., Miguel Goulao and Angelo C Lepore
Fumarate modulates the immune/inflammatory response and rescues nerve cells and neurological function after stroke in rats., Ruihe Lin, Jingli Cai, Eric W Kostuk, Robert H. Rosenwasswer MD, and Lorraine Iacovitti
Cell-to-Cell Transmission of Dipeptide Repeat Proteins Linked to C9orf72-ALS/FTD., Thomas Westergard, Brigid K Jensen, Xinmei Wen, Jingli Cai, Elizabeth Kropf, Lorraine Iacovitti, Piera Pasinelli, and Davide Trotti
Submissions from 2015
Dysregulation of Kv3.4 channels in dorsal root ganglia following spinal cord injury., David Ritter, Benjamin M Zemel, Tamara J Hala, Michael E O'Leary, Angelo C Lepore, and Manuel Covarrubias
Submissions from 2014
Overexpression of the astrocyte glutamate transporter GLT1 exacerbates phrenic motor neuron degeneration, diaphragm compromise, and forelimb motor dysfunction following cervical contusion spinal cord injury., Ke Li, Charles Nicaise, Daniel Sannie, Tamara J Hala, Elham Javed, Jessica L Parker, Rajarshi Putatunda, Kathleen A Regan, Valérie Suain, Jean-Pierre Brion, Fred Rhoderick, Megan C Wright, David J Poulsen, and Angelo C Lepore
Submissions from 2013
Tracking transplanted bone marrow stem cells and their effects in the rat MCAO stroke model., Gregory V Goldmacher, Rena Nasser, Daniel Y Lee, Sargon Yigit, Robert Rosenwasser, and Lorraine Iacovitti
Impairments in neurogenesis are not tightly linked to depressive behavior in a transgenic mouse model of Alzheimer's disease., Daniel M Iascone, Sneha Padidam, Mark S Pyfer, Xiaohong Zhang, Lijuan Zhao, and Jeannie Chin
Behavioral and transcriptome alterations in male and female mice with postnatal deletion of TrkB in dorsal striatal medium spiny neurons., Ellen M Unterwald, Michelle E. Page, Timothy B Brown, Jonathan S Miller, Marta Ruiz, Karen A Pescatore, Baoji Xu, Louis French Reichardt, Joel Beverley, Bin Tang, Heinz Steiner, Elizabeth A Thomas, and Michelle E Ehrlich
Submissions from 2012
Corticothalamic dysfunction and cognitive deficits in a mouse model of Alzheimer's disease, Brian Corbett, Xiaohong Zhang, Lijuan Zhao, and Jeannie Chin
Modeling-independent elucidation of inactivation pathways in recombinant and native A-type Kv channels., Jeffrey D Fineberg, David M Ritter, and Manuel Covarrubias
Loss of axonal mitochondria promotes tau-mediated neurodegeneration and Alzheimer's disease-related tau phosphorylation via PAR-1., Kanae Iijima-Ando, Michiko Sekiya, Akiko Maruko-Otake, Yosuke Ohtake, Emiko Suzuki, Bingwei Lu, and Koichi M Iijima
dyschronic, a Drosophila homolog of a deaf-blindness gene, regulates circadian output and Slowpoke channels., James E C Jepson, Mohammad Shahidullah, Angelique Lamaze, Drew Peterson, Huihui Pan, and Kyunghee Koh
Egr-1 induces DARPP-32 expression in striatal medium spiny neurons via a conserved intragenic element., Serene Keilani, Samira Chandwani, Georgia Dolios, Alexey Bogush, Heike Beck, Antonis K Hatzopoulos, Gadiparthi N Rao, Elizabeth A Thomas, Rong Wang, and Michelle E Ehrlich
Msh2 acts in medium-spiny striatal neurons as an enhancer of CAG instability and mutant huntingtin phenotypes in Huntington's disease knock-in mice., Marina Kovalenko, Ella Dragileva, Jason St Claire, Tammy Gillis, Jolene R Guide, Jaclyn New, Hualing Dong, Raju Kucherlapati, Melanie H Kucherlapati, Michelle E Ehrlich, Jong-Min Lee, and Vanessa C Wheeler
Glucose decouples intracellular Ca2+ activity from glucagon secretion in mouse pancreatic islet alpha-cells., Sylvain J Le Marchand and David W Piston
Severe stress switches CRF action in the nucleus accumbens from appetitive to aversive., Julia C Lemos, Matthew J Wanat, Jeffrey S Smith, Beverly A S Reyes, Nick G Hollon, Elisabeth J Van Bockstaele, Charles Chavkin, and Paul E M Phillips
Submissions from 2011
Amyloid-beta/Fyn–Induced Synaptic, Network, and Cognitive Impairments Depend on Tau Levels in Multiple Mouse Models of Alzheimer’s Disease, Erik D. Roberson, Brian Halabisky, Jong W. Yoo, Jinghua Yao, Jeannie Chin, Fengrong Yan, Tiffany Wu, Patricia Hamto, Nino Devidze, Gui-Qiu Yu, Jorge J. Palop, Jeffrey L. Noebels, and Lennart Mucke
Characterization of the Drosophila SLOWPOKE binding protein (SLOB) promoter, Amanda L. Sheldon, Lauren Manderfield, and Irwin B. Levitan
Submissions from 2010
Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS., Daryl A Bosco, Gerardo Morfini, N Murat Karabacak, Yuyu Song, Francois Gros-Louis, Piera Pasinelli, Holly Goolsby, Benjamin A Fontaine, Nathan Lemay, Diane McKenna-Yasek, Matthew P Frosch, Jeffrey N Agar, Jean-Pierre Julien, Scott T Brady, and Robert H Brown
Dopaminergic neurons derived from human induced pluripotent stem cells survive and integrate into 6-OHDA-lesioned rats., Jingli Cai, Ming Yang, Elizabeth Poremsky, Sarah Kidd, Jay S Schneider, and Lorraine Iacovitti
ALS-linked mutant SOD1 damages mitochondria by promoting conformational changes in Bcl-2., Steve Pedrini, Daniela Sau, Stefania Guareschi, Marina Bogush, Robert H Brown, Nicole Naniche, Azadeh Kia, Davide Trotti, and Piera Pasinelli
Submissions from 2009
Human amniotic fluid stem cells do not differentiate into dopamine neurons in vitro or after transplantation in vivo., Angela E Donaldson, Jingli Cai, Ming Yang, and Lorraine Iacovitti
Evidence for beta1-adrenergic receptor involvement in amygdalar corticotropin-releasing factor gene expression: implications for cocaine withdrawal., Carla A Rudoy, Arith-Ruth S Reyes, and E. J. Van Bockstaele
Submissions from 2008
Gene expression profile of neuronal progenitor cells derived from hESCs: activation of chromosome 11p15.5 and comparison to human dopaminergic neurons., William J Freed, Jia Chen, Cristina M Bäckman, Catherine M Schwartz, Tandis Vazin, Jingli Cai, Charles E Spivak, Carl R Lupica, Mahendra S Rao, and Xianmin Zeng
Trk: a neuromodulator of age-specific behavioral and neurochemical responses to cocaine in mice., Michelle Niculescu, Shane A Perrine, Jonathan S Miller, Michelle E Ehrlich, and Ellen M Unterwald
Submissions from 2007
Evidence against roles for phorbol binding protein Munc13-1, ADAM adaptor Eve-1, or vesicle trafficking phosphoproteins Munc18 or NSF as phospho-state-sensitive modulators of phorbol/PKC-activated Alzheimer APP ectodomain shedding., Annat F Ikin, Mirsada Causevic, Steve Pedrini, Lyndsey S Benson, Joseph D Buxbaum, Toshiharu Suzuki, Simon Lovestone, Shigeki Higashiyama, Tomas Mustelin, Robert D Burgoyne, and Sam Gandy
The role of presenilin and its interacting proteins in the biogenesis of Alzheimer's beta amyloid., Giuseppe Verdile, Samuel E Gandy, and Ralph N Martins
Submissions from 2004
Similar promotion of Abeta1-42 fibrillogenesis by native apolipoprotein E epsilon3 and epsilon4 isoforms., David Sweeney, Ralph Martins, Harry LeVine, Jonathan D Smith, and Sam Gandy
