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Manuscripts from 2024

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CYP26A1 Links WNT and Retinoic Acid Signaling: A Target to Differentiate ALDH+ Stem Cells in APC-Mutant CRC, Caroline O.B. Facey, Victoria O. Hunsu, Chi Zhang, Brian Osmond, Lynn M. Opdenaker, and Bruce M. Boman

Manuscripts from 2023

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Intestinal Neuropod Cell GUCY2C Regulates Visceral Pain, Joshua R. Barton, Annie K. Londregran, Tyler D. Alexander, Ariana A. Entezari, Shely Bar-Ad, Lan Cheng, Angelo C. Lepore, Adam E. Snook, Manuel Covarrubias, and Scott A. Waldman

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A Review of IsomiRs in Colorectal Cancer, Molly A. Lausten and Bruce M. Boman

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Comparison of Bacterial Culture With Biofire® Filmarray® Multiplex PCR Screening of Archived Cerebrospinal Fluid Specimens From Children With Suspected Bacterial Meningitis in Nigeria, S Obaro, F Hassan-Hanga, N Medugu, Rasaq Olaosebikan, G Olanipekun, B Jibir, S Gambo, Theresa Ajose, Carissa Duru, B Ebruke, and H D Davies

Manuscripts from 2022

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Circulating Messenger RNA Variants as a Potential Biomarker for Surveillance of Hepatocellular Carcinoma, Timothy Block, Daniel Zezulinski, David E. Kaplan, Jingqiao Lu, Samantha Zanine, Tingting Zhan, Cataldo Doria, and Aejaz Sayeed

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Guanylyl cyclase C as a Diagnostic and Therapeutic Target in Colorectal Cancer, Adi Caspi, Ariana A. Entezari, Madison Crutcher, Adam E. Snook, and Scott A. Waldman

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Pharmacologic Ascorbic Acid as Early Therapy for Hospitalized Patients with COVID-19: A Randomized Clinical Trial, Dagan Coppock, Pierre-Christian Violet, Gustavo Vasquez, Katherine Belden, Michael Foster, Bret Mullin, Devon Magee, Isabelle Mikell, Lokesh Shah, Victoria Powers, Brian Curcio, Daniel A. Monti, and Mark Levine

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T-Cell Responses to Immunodominant Listeria Epitopes Limit Vaccine-Directed Responses to the Colorectal Cancer Antigen, Guanylyl Cyclase C, John C. Flickinger, Jagmohan Singh, Yanki Yarman, Robert D Carlson, Joshua Barton, Scott A Waldman, and Adam E. Snook

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Functional Assessment of Missense Variants in the ABCC6 Gene Implicated in Pseudoxanthoma Elasticum, a Heritable Ectopic Mineralization Disorder., Luke Kowal, Jianhe Huang, Hongbin Luo, Jagmohan Singh, Adam E Snook, Jouni Uitto, and Qiaoli Li

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Spatial Metrics of Interaction between CD163-Positive Macrophages and Cancer Cells and Progression-Free Survival in Chemo-Treated Breast Cancer, Brenton Maisel, Misung Yi, Amy R Peck, Yunguang Sun, Jeffrey A Hooke, Albert J Kovatich, Craig D Shriver, Hai Hu, Marja T Nevalainen, Takemi Tanaka, Nicole L Simone, Li Lily Wang, Hallgeir Rui, and I Chervoneva

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A Prospective Cohort Study of the Clinical Predictors of Bacteremia in Under-Five Children With Acute Undifferentiated Fever Attending a Secondary Health Facility in Northwestern Nigeria, Taofik Oluwaseun Ogunkunle, Timothy Olanrewaju Adedoyin, Samuel Kolade Ernest, Fatimah Hassan-Hanga, Abdulazeez Imam, Rasaq Olaosebikan, and Stephen K Obaro

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HOXA9 Overexpression Contributes to Stem Cell Overpopulation That Drives Development and Growth of Colorectal Cancer, Brian Osmond, Caroline O.B. Facey, Chi Zhang, and Bruce M. Boman

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Ondansetron to Reduce Neonatal Opioid Withdrawal Severity: A Randomized Clinical Trial, Gary Peltz, Lauren M. Jansson, Susan Adeniyi-Jones, Carol Cohane, David Drover, Steven Shafer, Meiyue Wang, Manhong Wu, Balaji Govindaswami, Priya Jegatheesan, Cynthia Argani, Salwa Kahn, and Walter K. Kraft

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Development and Preclinical Investigation of Physically Cross-Linked and pH-Sensitive Polymeric Gels as Potential Vaginal Contraceptives, Ankit K. Rochani, Vivek Agrahari, Neelima Chandra, Onkar N Singh, Timothy J McCormick, Gustavo F Doncel, Meredith R Clark, and Gagan Kaushal

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Targeting gastrointestinal cancers with chimeric antigen receptor (CAR)-T cell therapy, Ross E Staudt, Robert D Carlson, and Adam E. Snook

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Age Moderates the Effect of Injury Severity on Functional Trajectories in Traumatic Brain Injury: A Study Using the NIDILRR Traumatic Brain Injury Model Systems National Dataset., Laraine Winter, Janell L Mensinger, Helene J Moriarty, Keith M Robinson, Michelle McKay, and Benjamin E Leiby

Manuscripts from 2021

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THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Catalytic receptors, Stephen PH Alexander, Doriano Fabbro, Eamonn Kelly, Alistair Mathie, John A Peters, Emma L Veale, Jane F Armstrong, Elena Faccenda, Simon D Harding, Adam J Pawson, Christopher Southan, Jamie A Davies, Annie Beuve, Peter Brouckaert, Clare Bryant, John C Burnett, Richard W Farndale, Andreas Friebe, John Garthwaite, Adrian J Hobbs, Gavin E Jarvis, Michaela Kuhn, David MacEwan, Tom P Monie, Andreas Papapetropoulos, Lincoln R Potter, Harald H H W Schmidt, Csaba Szabo, and Scott A Waldman

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Choline-Sigma-1R as an Additional Mechanism for Potentiation of Orexin by Cocaine, Jeffrey Barr, Pingwei Zhao, G Cristina Brailoiu, and Eugen Brailoiu

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Seeking Similarities Rather Than Differences With Adults to Aid in Therapeutic Advancement for Children., Mara L. Becker and Walter K. Kraft

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Longitudinal evaluation of azithromycin and cytokine concentrations in amniotic fluid following one-time oral dosing in pregnancy., Rupsa C. Boelig, Edwin Lam, Ankit Rochani, Gagan Kaushal, Amanda Roman, and Walter K. Kraft

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Emerging targets for the diagnosis of Parkinson's disease: examination of systemic biomarkers., Lara Cheslow, Adam E. Snook, and Scott A. Waldman

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Retinoids as Chemo-Preventive and Molecular-Targeted Anti-Cancer Therapies., Victoria O. Hunsu, Caroline O.B. Facey, Jeremy Z. Fields, and Bruce M. Boman

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A Randomized Trial to Improve Adherence to Follow-up Eye Examinations Among People With Glaucoma, Benjamin E Leiby, Sarah E. Hegarty, Tingting Zhan, Jonathan S Myers, L Jay Katz, Julia A Haller, Michael Waisbourd, Christine Burns, Meskerem Divers, Jeanne Molineaux, Jeffrey Henderer, Charles Brodowski, and Lisa A Hark

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Apixaban Discontinuation for Invasive Or major Surgical procedures (ADIOS): A prospective cohort study., Geno J. Merli, Walter K. Kraft, Luis H. Eraso, Taki Galanis, Lynda J. Thomson, Geoffrey O. Ouma, Eugene Viscusi, Jerald Z. Gong, and Edwin Lam

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Correlations between Coffee Consumption and Metabolic Phenotypes, Plasma Folate, and Vitamin B12: NHANES 2003 to 2006., Pratibha V Nerurkar, Krupa Gandhi, and John J Chen

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Level of utilization and provider-related barriers to the use of hydroxyurea in the treatment of sickle cell disease patients in Jos, North-Central Nigeria, Akinyemi O.D. Ofakunrin, Edache S. Okpe, Tolulope O. Afolaranmi, Rasaq Olaosebikan, Patience U. Kanhu, Kehinde Adekola, Nantok Dami, and Atiene S. Sagay

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Review article: diagnosis, management and patient perspectives of the spectrum of constipation disorders., Amol Sharma, Satish S C Rao, Kimberly Kearns, Kimberly D Orleck, and Scott A Waldman

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The Role of miRNAs, miRNA Clusters, and isomiRs in Development of Cancer Stem Cell Populations in Colorectal Cancer., Victoria A Stark, Caroline O B Facey, Vignesh Viswanathan, and Bruce M Boman

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Point-of-Care Lung Ultrasound for COVID-19: Findings and Prognostic Implications From 105 Consecutive Patients, Kosuke Yasukawa, Taro Minami, David R Boulware, Ayako Shimada, and Ernest A Fischer

Manuscripts from 2020

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Unexpected cell type-dependent effects of autophagy on polyglutamine aggregation revealed by natural genetic variation in C. elegans., J Alexander-Floyd, S Haroon, M Ying, A A Entezari, C Jaeger, M Vermulst, and T Gidalevitz

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APC-β-catenin-TCF signaling silences the intestinal guanylin-GUCY2C tumor suppressor axis., Erik S Blomain, Jeffrey A Rappaport, Amanda M Pattison, Babar Bashir, Ellen Caparosa, Jonathan Stem, Adam E Snook, and Scott A Waldman

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Autocatalytic Tissue Polymerization Reaction Mechanism in Colorectal Cancer Development and Growth., Bruce M Boman, Arthur Guetter, Ryan M Boman, and Olaf A Runquist

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Development of an abbreviated symptom score for the neonatal abstinence syndrome., I. Chervoneva, S. C. Adeniyi-Jones, F. Blanco, and W. K. Kraft

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Chimeric Ad5.F35 vector evades anti-adenovirus serotype 5 neutralization opposing GUCY2C-targeted antitumor immunity, John C. Flickinger, Jagmohan Singh, Robert D Carlson, Elinor Leong, Trevor R. Baybutt, Joshua Barton, Ellen M. Caparosa, Amanda M. Pattison, Jeff A. Rappaport, Jamin Roh, Tingting Zhan, Babar Bashir, Scott A Waldman, and Adam E. Snook

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Epidemiology of COVID-19 and Predictors of Outcome in Nigeria: A Single-Center Study., Olayinka Rasheed Ibrahim, Bello Muhammed Suleiman, Suleiman Bello Abdullahi, Taofeek Oloyede, Abdallah Sanda, Maruf Sanusi Gbadamosi, Bashir Olajide Yusuf, Rabilu Yandoma Iliyasu, Lawal Magaji Ibrahim, Adamu Danladi Dawud, Sulaiman Saidu Bashir, Nwawueze Efam Okonta, Wasinda Francis Umar, Abiodun Gbenga Tekobo, Muhammadu Sani Abubakar, Bashir Taiye Aminu, Shuaibu Onoruoyiza Ibrahim, Rasaq Olaosebikan, and Olugbenga Ayodeji Mokuolu

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Mobilizing Toxins for Cancer Treatment: Historical Perspectives and Current Strategies., Jessica Kopenhaver, Robert D Carlson, and Adam E Snook

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Vancomycin in peritoneal dialysis: Clinical pharmacology considerations in therapy., Edwin Lam, Yi Ting Kayla Lien, Walter K. Kraft, Beth Piraino, Valvanera Vozmediano, Stephan Schmidt, and Jingjing Zhang

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Twice-Daily Doravirine Overcomes the Interaction Effect from Once-Weekly Rifapentine and Isoniazid in Healthy Volunteers., Edwin Lam, Joseph Schaefer, Richard Zheng, Tingting Zhan, and Walter K. Kraft

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Simulation-based mastery learning compared to standard education for discussing diagnostic uncertainty with patients in the emergency department: a randomized controlled trial., Danielle M. McCarthy, Rhea E. Powell, Kenzie A. Cameron, David H. Salzman, Dimitrios Papanagnou, Amanda Doty, Benjamin E. Leiby, Katherine Piserchia, Matthew R. Klein, Xiao C. Zhang, William C. McGaghie, and Kristin L. Rising

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Functional Blockade of E-Selectin in Tumor-Associated Vessels Enhances Anti-Tumor Effect of Doxorubicin in Breast Cancer, Yoshihiro Morita, Macall Leslie, Hiroyasu Kameyama, Ganesh L R Lokesh, Norihisa Ichimura, Rachel Davis, Natalie Hills, Nafis Hasan, Roy Zhang, Yuji Kondo, David G Gorenstein, David E Volk, Inna Chervoneva, Hallgeir Rui, and Takemi Tanaka

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Fatal case of newborn Lassa fever virus infection mimicking late onset neonatal sepsis: a case report from northern Nigeria, Taofik Oluwaseun Ogunkunle, Surajudeen Oyeleke Bello, Chinwe Immaculata Anderson, Rashida Musa, Rasaq Olaosebikan, and Abdulazeez Imam

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MicroRNA Expression Profiling of Normal and Malignant Human Colonic Stem Cells Identifies, Vignesh Viswanathan, Lynn Opdenaker, Shirin Modarai, Jeremy Z Fields, Gregory Gonye, and Bruce M Boman

Manuscripts from 2019

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No meaningful drug interactions with doravirine, lamivudine and tenofovir disoproxil fumarate co-administration., Matt S. Anderson, Jocelyn Gilmartin, Li Fan, Ka Lai Yee, Walter K. Kraft, Ilias Triantafyllou, Christina Reitmann, Ying Guo, Rachael Liu, and Marian Iwamoto

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Silencing the GUCA2A-GUCY2C tumor suppressor axis in CIN, serrated, and MSI colorectal neoplasia., Babar Bashir, Dante J. Merlino, Jeff A. Rappaport, Esteban Gnass, Juan P. Palazzo, Ying Feng, Eric R R. Fearon, Adam E. Snook, and Scott A. Waldman

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Advances in Chimeric Antigen Receptor T-Cell Therapies for Solid Tumors., Trevor R. Baybutt, John C. Flickinger, Ellen M. Caparosa, and Adam E. Snook

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Antibody responses against the vaccine antigens Ov-103 and Ov-RAL-2 are associated with protective immunity to Onchocerca volvulus infection in both mice and humans., Parakkal Jovvian George, Jessica A. Hess, Sonia Jain, John B. Patton, Tingting Zhan, Nancy Tricoche, Bin Zhan, Maria Elena Bottazzi, Peter J. Hotez, David Abraham, and Sara Lustigman

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Non-Thermal Plasma-Induced Immunogenic Cell Death in Cancer: A Topical Review., Marian Khalili, Lynsey Daniels, Abraham Lin, Fred C. Krebs, Adam E. Snook, Sander Bekeschus, Wilbur B. Bowne, and Vandana Miller

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Drug interactions between direct-acting oral anticoagulants and calcineurin inhibitors during solid organ transplantation: considerations for therapy, Edwin Lam, Babar Bashir, Mark Chaballa, and Walter K. Kraft

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Pharmacokinetics of Ketamine at Dissociative Doses in an Adult Patient With Refractory Status Asthmaticus Receiving Extracorporeal Membrane Oxygenation Therapy., Edwin Lam, Ankit K. Rochani, Gagan Kaushal, Brandi N. Thoma, Julian Tanjuakio, Frances Mae West, and Hitoshi Hirose

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Pharmacological and non-pharmacological treatments for the Neonatal Abstinence Syndrome (NAS)., A. K. Mangat, G. M. Schmölzer, and W. K. Kraft

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Quantitative sensory testing in children with sickle cell disease: additional insights and future possibilities., Robin E. Miller, Dawn S. Brown, Scott W. Keith, Sarah E. Hegarty, Yamaja Setty, Claudia M. Campbell, Suzanne M. McCahan, Suhita Gayen-Betal, Hal Byck, and Marie Stuart

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Split tolerance permits safe Ad5-GUCY2C-PADRE vaccine-induced T-cell responses in colon cancer patients., Adam E. Snook, Trevor R. Baybutt, Bo Xiang, Tara S. Abraham, John C. Flickinger, Terry Hyslop, Tingting Zhan, Walter K. Kraft, Takami Sato, and Scott A. Waldman

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Efficacy and safety of intravenous golimumab plus methotrexate in patients with rheumatoid arthritis aged < 65 years and those ≥ 65 years of age., John Tesser, Shelly Kafka, Raphael J. DeHoratius, Stephen Xu, Elizabeth C Hsia, and Anthony Turkiewicz

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Blunted Evoked Prouroguanylin Endocrine Secretion in Chronic Constipation., Scott A. Waldman, Renata Tenenbaum, Henry C. Foehl, Peter Winkle, and Patrick Griffin

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Health Care Evolves From Reactive to Proactive., Scott A. Waldman and Andre Terzic

Manuscripts from 2018

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Neonatal Safety Information Reported to the FDA During Drug Development Studies., Debbie Avant, Gerri Baer, Jason N. Moore, Panli Zheng, Alfred Sorbello, Ron Ariagno, Lynne Yao, Gilbert J. Burckart, and Jian Wang

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Evaluating comfort measures for commonly performed painful procedures in pediatric patients., Sana Dastgheyb, Keith Fishlock, Constantine Daskalakis, Jami Kessel, and Paul Rosen

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Listeria monocytogenes as a vector for cancer immunotherapy: Current understanding and progress, John C. Flickinger, Ulrich Rodeck, and Adam E. Snook

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Buprenorphine in Neonatal Abstinence Syndrome., Walter K. Kraft

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Visual field changes in professional wind versus non-wind musical instrument players in the Philadelphia orchestra, Shuai‑Chun Lin, Cindy X. Zheng, Michael Waisbourd, Jeanne Molineaux, Lichuan Zeng, Tingting Zhan, Kamran Rahmatnejad, Arthur Resende, Anand V. Mantravadi, Lisa A. Hark, Marlene R. Moster, Joseph I. Markoff, George L. Spaeth, and L. Jay Katz

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Human GUCY2C-Targeted Chimeric Antigen Receptor (CAR)-Expressing T Cells Eliminate Colorectal Cancer Metastases., Michael S. Magee, Tara S. Abraham, Trevor R. Baybutt, John C. Flickinger, Natalie A. Ridge, Glen P Marszalowicz, Priyanka Prajapati, Adam R. Hersperger, Scott A. Waldman, and Adam E. Snook

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The anti-cancer effect of retinoic acid signaling in CRC occurs via decreased growth of ALDH+ colon cancer stem cells and increased differentiation of stem cells, Shirin R. Modarai, Anindita Gupta, Lynn M. Opdenaker, Ryan Kowash, Gabriel Masters, Vignesh Viswanathan, Tao Zhang, Jeremy Z. Fields, and Bruce M. Boman

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The Guanylate Cyclase C-cGMP Signaling Axis Opposes Intestinal Epithelial Injury and Neoplasia., Jeffrey A. Rappaport and Scott A. Waldman

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Process Improvement for Maximized Therapeutic Innovation Outcome., Scott A. Waldman and Andre Terzic

Manuscripts from 2017

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Guanylate cyclase C as a target for prevention, detection, and therapy in colorectal cancer., Allison A. Aka, Jeff A. Rappaport, Amanda M. Pattison, Takami Sato, Adam E. Snook, and Scott A. Waldman

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The Heat-Stable Enterotoxin Receptor, Guanylyl Cyclase C, as a Pharmacological Target in Colorectal Cancer Immunotherapy: A Bench-to-Bedside Current Report., Trevor R. Baybutt, Allison A. Aka, and Adam E. Snook

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GUCY2C maintains intestinal LGR5+ stem cells by opposing ER stress, Crystal Kraft, Jeff A. Rappaport, Adam E. Snook, Amanda M. Pattison, John P. Lynch, and Scott A. Waldman

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ST-Producing E. coli Oppose Carcinogen-Induced Colorectal Tumorigenesis in Mice., Peng Li, Jieru E. Lin, Adam E. Snook, and Scott A. Waldman

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GUCY2C Signaling Opposes the Acute Radiation-Induced GI Syndrome., Peng Li, Evan Wuthrick, Jeff A. Rappaport, Crystal Kraft, Jieru E. Lin, Glen Marszalowicz, Adam E. Snook, Tingting Zhan, Terry M. Hyslop, and Scott A. Waldman

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Extensions of D-optimal Minimal Designs for Symmetric Mixture Models., Yanyan Li, Damaraju Raghavarao, and Inna Chervoneva

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Tumor necrosis factor inhibitors in psoriatic arthritis., Santhi Mantravadi, Alexis Ogdie, and Walter K. Kraft

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Pathologic evaluation of tumor-associated macrophage density and vessel inflammation in invasive breast carcinomas, Yoshihiro Morita, Roy Zhang, Macall Leslie, Smita Adhikari, Nafis Hasan, Inna Chervoneva, Hallgeir Rui, and Takemi Tanaka

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Clinical Pharmacology & Therapeutics: Past, Present, and Future., Scott A. Waldman and Andre Terzic

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Peer Review Certifies Quality and Innovation in Clinical Pharmacology & Therapeutics., Scott A. Waldman and Andre M. Terzic

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Bioactivity of Oral Linaclotide in Human Colorectum for Cancer Chemoprevention., David S. Weinberg, Jieru E. Lin, Nathan R. Foster, Gary Della'Zanna, Asad Umar, Drew Seisler, walter K. Kraft, David M. Kastenberg, Leo C. Katz, Paul J. Limburg, and Scott A. Waldman

Manuscripts from 2016

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Editorial: Ferid murad, at 80: A legacy of science, medicine, and mentorship, Atta-Ur-Rahman

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The landscape of pancreatic cancer therapeutic resistance mechanisms, Saswati N. Chand; Kevin O’Hayer; Fernando F. Blanco; Jordan M Winter; and Jonathan Brody, MD

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Effect of Vorapaxar Alone and in Combination with Aspirin on Bleeding Time and Platelet Aggregation in Healthy Adult Subjects., Walter K. Kraft, J H Gilmartin, D L Chappell, F Gheyas, B M Walker, S Nagalla, U P Naik, J C Horrow, R E Wrishko, S Zhang, and M S Anderson

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Neonatal abstinence syndrome: Pharmacologic strategies for the mother and infant., Walter K. Kraft, Megan W. Stover, and Jonathan M. Davis

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Obesity-Induced Colorectal Cancer Is Driven by Caloric Silencing of the Guanylin-GUCY2C Paracrine Signaling Axis., Jieru E. Lin, Francheska Colon-Gonzalez, Erik S. Blomain, Gilbert W. Kim, Amanda Aing, Brian Stoecker, Justin Rock, Adam E. Snook, Tingting Zhan, Terry M. Hyslop, Michal Tomczak, Richard S. Blumberg, and Scott A. Waldman

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Role of a plausible nuisance contributor in the declining obesity-mortality risks over time., Tapan Mehta, Nicholas m. Pajewski, Scott W. Keith, Kevin Fontaine, and David B. Allison

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Pharmacologic and clinical evaluation of posaconazole., Jason N. Moore, Jason R. Healy, and Walter K. Kraft

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Impossibility to eliminate observer effect in the assessment of adherence in clinical trials., Jonathan S. Myers, Scott J. Fudemberg, Robert E. Fintelmann, Lisa A. Hark, Nitasha Khanna, Benjamin E. Leiby, and Michael Waisbourd

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A survey of physician receptivity to molecular diagnostic testing and readiness to act on results for early-stage colon cancer patients., Ronald E. Myers, Thomas Wolf, Phillip Shwae, Sarah E. Hegarty, Stephen C. Peiper, and Scott A. Waldman

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Reversibility of Apixaban Anticoagulation with a Four-Factor Prothrombin Complex Concentrate in Healthy Volunteers., S Nagalla, Lynda Thomson, Y Oppong, B Bachman, I Chervoneva, and walter k. Kraft

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Big Data Transforms Discovery-Utilization Therapeutics Continuum., Scott A. Waldman and Andre Terzic

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Bioinnovation Enterprise: An engine driving breakthrough therapies., Scott A. Waldman and Andre Terzic

Manuscripts from 2015

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Association of Adipokines with Insulin Resistance, Microvascular Dysfunction, and Endothelial Dysfunction in Healthy Young Adults., Cindy Cheng, MD, PhD and Constantine Daskalakis

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Adolescent and adult African Americans have similar metabolic dyslipidemia., Samuel S. Gidding, Scott W. Keith, and Bonita Falkner

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Ketamine for the treatment of depression in patients receiving hospice care: a retrospective medical record review of thirty-one cases., Alana Iglewicz, Katherine Morrison, Richard A. Nelesen, Tingting Zhan, Boris Iglewicz, Nathan Fairman, Jeremy M. Hirst, and Scott A. Irwin

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No Evidence of a Drug-Drug Interaction Between Letermovir (MK-8228) and Mycophenolate Mofetil, WL Marshall; C. Badshah; F. Liu; Walter K. Kraft, MD; F. Colon-Gonzalez; A. van Schanke; CR. Cho; E. Hulskotte; JR Butterton; and EE Marcantonio

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GM1 ganglioside in Parkinson's disease: Pilot study of effects on dopamine transporter binding., Jay S. Schneider, Franca Cambi, Stephen M. Gollomp, Hiroto Kuwabara, James R. Brašić, Benjamin E. Leiby, Stephanie Sendek, and Dean F. Wong

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Companion diagnostics at the intersection of personalized medicine and healthcare delivery., Scott A Waldman and Andre Terzic

Manuscripts from 2014

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Evidence for role of acid-sensing ion channels in nucleus ambiguus neurons: essential differences in anesthetized versus awake rats., G Cristina Brailoiu, Elena Deliu, Joseph Altmann, Vineet Chitravanshi, and Eugen Brailoiu

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ASA Section on Teaching of Statistics in the Health Sciences: 25 Years Later, Constantine Daskalakis, ScD

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Posaconazole Tablet Pharmacokinetics: Lack of Effect of Concomitant Medications Altering Gastric pH and Gastric Motility in Healthy Subjects., Walter K. Kraft, Peter S. Chang, Marlou L P S van Iersel, Hetty Waskin, Gopal Krishna, and Wendy M Kersemaekers

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Ethanol Pharmacokinetics in Neonates and Infants, Elizabeth Marek, PharmD. and Walter K. Kraft, MD

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GUCY2C lysosomotropic endocytosis delivers immunotoxin therapy to metastatic colorectal cancer., Glen P Marszalowicz, Adam E. Snook, Michael Sullivan Magee, Dante Merlino, Lisa D Berman-Booty, and Scott A Waldman

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Obesity and mortality: are the risks declining? Evidence from multiple prospective studies in the United States., Tapan S. Mehta, Kevin R. Fontaine, Scott W. Keith, Sripal S. Bangalore, Gustavo de los Campos, Alfred Bartolucci, Nicholas M. Pajewski, and David B. Allison

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Impact of Preadmission Beta-blocker Use on Cardiac Abnormalities and In-hospital Mortality in Patients with Aneurysmal Subarachnoid Hemorrhage, Toshimasa Okabe, MD; Anushya Jeyabalan, MD; Benjamin E. Leiby, PhD; Fred Rincon, MD; and Walter K. Kraft, MD