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Manuscripts from 2016

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Drugs for preventing red blood cell dehydration in people with sickle cell disease., Srikanth Nagalla and Samir K. Ballas

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Ca2+/calmodulin/MLCK pathway initiates, and RhoA/ROCK maintains, the internal anal sphincter smooth muscle tone., Satish Rattan

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Cannibalism, Kuru, and Mad Cows: Prion Disease As a "Choose-Your-Own-Experiment" Case Study to Simulate Scientific Inquiry in Large Lectures., Antonio Serrano, Jeffrey Liebner, and Justin K Hines

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A 22-year-old man with pleural tuberculosis associated hydropneumothorax: Case report and literature review., Lauren A Sharan; Thea Price, MD; Boyd Hehn; David Manoff, MD; and Scott W. Cowan, MD

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Hospitalized Patients at High Risk for Obstructive Sleep Apnea Have More Rapid Response System Events and Intervention Is Associated with Reduced Events., Sunil Sharma, MD; Anindita Chowdhury; Lili Tang; Leslee Willes; Brian Glynn; and Stuart F Quan

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Aging-associated changes in microRNA expression profile of internal anal sphincter smooth muscle: role of microRNA-133a., Jagmohan Singh; Boopathi Ettickan; Sankar Addya; Benjamin Philllips; Isidore Rigoutsos; Raymond B. Penn, PhD; and Satish Rattan

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Aging-associated changes in microRNA expression profile of internal anal sphincter smooth muscle: Role of microRNA-133a., Jagmohan Singh, Boopathi Ettickan, Sankar Addya, Benjamin Philllips, Isidore Rigoutsos, Raymond B. Penn, and Satish Rattan

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Postoperative intussusception in 10-year-old presenting as decreased intestinal motility, Arielle Spellun, Loren Berman, and Stephen Murphy

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Conversion to eslicarbazepine acetate monotherapy: A pooled analysis of 2 phase III studies., Michael R Sperling, Jacqueline French, Mercedes P Jacobson, Ladislav Pazdera, Mallory Gough, Hailong Cheng, Todd Grinnell, and David Blum

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Reduction of CTRP9, a novel anti-platelet adipokine, contributes to abnormal platelet activity in diabetic animals., Wenqing Wang, Wayne Bond Lau, Yajing Wang, Xin-Liang Ma, and Rong Li

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Neural crest cell-autonomous roles of fibronectin in cardiovascular development., Xia Wang and Sophie Astrof

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Preparation and biological activity of the monoclonal antibody against the second extracellular loop of the angiotensin II type 1 receptor, Mingming Wei, Chengrui Zhao, Suli Zhang, Li Wang, Huirong Liu, and Xin-Liang Ma

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Stimulation of Transforming Growth Factor-β1-Induced Endothelial-To-Mesenchymal Transition and Tissue Fibrosis by Endothelin-1 (ET-1): A Novel Profibrotic Effect of ET-1., Peter J. Wermuth, Zhaodong Li, Fabian A. Mendoza, and Sergio A. Jimenez

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Monthly "Grief Rounds" to Improve Residents' Experience and Decrease Burnout in a Medical Intensive Care Unit Rotation., Lindsay Wilde, Brooke Worster, and David Oxman

Manuscripts from 2015

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J-wave syndromes: Brugada and early repolarization syndromes., Charles Antzelevitch and Gan-Xin Yan

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Chimeric cells of maternal origin do not appear to be pathogenic in the juvenile idiopathic inflammatory myopathies or muscular dystrophy., Carol M Artlett, Sihem Sassi-Gaha, Ronald C Ramos, Frederick W Miller, and Lisa G Rider

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Estimation of daily interfractional larynx residual setup error after isocentric alignment for head and neck radiotherapy: quality assurance implications for target volume and organs-at-risk margination using daily CT on- rails imaging., Charles A Baron, Musaddiq J Awan, Abdallah S R Mohamed, Imad Akel, David I Rosenthal, G Brandon Gunn, Adam S Garden, Brandon A Dyer, Laurence Court, Parag R Sevak, Esengul Kocak-Uzel, and Clifton D Fuller

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Human Polyclonal Antibodies Produced through DNA Vaccination of Transchromosomal Cattle Provide Mice with Post-Exposure Protection against Lethal Zaire and Sudan Ebolaviruses., Callie E Bounds, Steven A Kwilas, Ana I Kuehne, Jennifer M Brannan, Russell R Bakken, John M Dye, Jay W Hooper, Lesley C Dupuy, Barry Ellefsen, Drew Hannaman, Hua Wu, Jin-An Jiao, Eddie J Sullivan, Connie S Schmaljohn, and Matthias J. Schnell

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Current Management of Heart Failure: When to Refer to Heart Failure Specialist and When Hospice is the Best Option., Behnam Bozorgnia and Paul J. Mather

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Fibronectin signals through integrin α5β1 to regulate cardiovascular development in a cell type-specific manner., Dongying Chen, Xia Wang, Dong Liang, Julie Gordon, Ashok Mittal, Nancy Manley, Karl Degenhardt, and Sophie Astrof

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Granular cell tumor of the common hepatic duct as an unusual cause of jaundice in a hepatitis C patient: looking beyond the tip of the iceberg!, Tripti R. Chopade, MBBS; Colin L. Smith, MD; Warren R. Maley, MD; Ali A. Siddiqui, MD; and David A. Sass, MD

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Anxiety and depression in patients with advanced macular degeneration: current perspectives., Verena R Cimarolli, Robin J Casten, Barry W. Rovner, Vera Heyl, Silvia Sörensen, and Amy Horowitz

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Vertebral Body Stapling versus Bracing for Patients with High-Risk Moderate Idiopathic Scoliosis., Laury Cuddihy, Aina J Danielsson, Patrick J Cahill, Amer F Samdani, Harsh Grewal, John M Richmond, M J Mulcahey, John P Gaughan, M Darryl Antonacci, and Randal R Betz

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Inflammatory Muscle Diseases., Marinos Dalakas

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Utility of the QT interval in predicting outcomes in patients presenting to the emergency department with chest pain., Toni A de Venecia; Marvin Y Lu; Chinualumogu C Nwakile; and Vincent M. Figueredo, M.D.

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Dysregulation of the haem-haemopexin axis is associated with severe malaria in a case-control study of Ugandan children., Robyn E Elphinstone, Frank Riley, Tian Lin, Sarah Higgins, Aggrey Dhabangi, Charles Musoke, Christine Cserti-Gazdewich, Raymond F. Regan, H Shaw Warren, and Kevin C Kain

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Low-density lipoprotein cholesterol lowering therapies: what is on the horizon?, Ramprasad Gadi and Vincent M. Figueredo, M.D.

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The Effect of Aspirin on Bleeding and Transfusion in Contemporary Cardiac Surgery., Jordan E Goldhammer, Gregary D. Marhefka, Constantine Daskalakis, Mark W Berguson, John E Bowen, James Diehl, and Jianzhong Sun

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Aspartate aminotransferase to platelet ratio index as a prospective predictor of hepatocellular carcinoma risk in patients with chronic hepatitis B virus infection., Hie-Won Hann; Shaogui Wan; Yinzhi Lai; Richard Hann; Ronald E. Myers, PhD, DSW; Fenil Patel; Kejin Zhang; Zhong Ye; Chun Wang; and Hushan Yang

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High Throughput Sequencing Identifies MicroRNAs Mediating α-Synuclein Toxicity by Targeting Neuroactive-Ligand Receptor Interaction Pathway in Early Stage of Drosophila Parkinson's Disease Model., Yan Kong, Xijun Liang, Lin Liu, Dongdong Zhang, Chao Wan, Zhenji Gan, Liudi Yuan, and Bing-Hua Jiang

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Practical management of anticoagulation in patients with atrial fibrillation., Richard J Kovacs, Greg C Flaker, Sherry J Saxonhouse, John U. Doherty, Kim K Birtcher, Adam Cuker, Bruce L Davidson, Robert P Giugliano, Christopher B Granger, Amir K Jaffer, Bella H Mehta, Edith Nutescu, and Kim A Williams

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DNA-Repair Defects and Olaparib in Metastatic Prostate Cancer., Joaquin Mateo, Suzanne Carreira, Shahneen Sandhu, Susana Miranda, Helen Mossop, Raquel Perez-Lopez, Daniel Nava Rodrigues, Dan Robinson, Aurelius Omlin, Nina Tunariu, Gunther Boysen, Nuria Porta, Penny Flohr, Alexa Gillman, Ines Figueiredo, Claire Paulding, George Seed, Suneil Jain, Christy Ralph, Andrew Protheroe, Syed Hussain, Robert Jones, Tony Elliott, Ursula McGovern, Diletta Bianchini, Jane Goodall, Zafeiris Zafeiriou, Chris T Williamson, Roberta Ferraldeschi, Ruth Riisnaes, Bernardette Ebbs, Gemma Fowler, Desamparados Roda, Wei Yuan, Yi-Mi Wu, Xuhong Cao, Rachel Brough, Helen Pemberton, Roger A'Hern, Amanda Swain, Lakshmi P Kunju, Rosalind Eeles, Gerhardt Attard, Christopher J Lord, Alan Ashworth, Mark A Rubin, Karen E Knudsen, Felix Y Feng, Arul M Chinnaiyan, Emma Hall, and Johann S de Bono

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Treatment-Induced Changes in Plasma Adiponectin Do Not Reduce Urinary Albumin Excretion in the Diabetes Prevention Program Cohort., Kieren J Mather, Qing Pan, William C Knowler, Tohru Funahashi, George A Bray, Richard Arakaki, Bonita Falkner, Kumar Sharma, and Barry J. Goldstein

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Expression of enteropathogenic Escherichia coli map is significantly different than that of other type III secreted effectors in vivo., Mai Nguyen, Jason Rizvi, and Gail Hecht

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Significance of QRS duration in non-ST elevation myocardial infarction., Chinualumogu Nwakile; Bhaskar Purushottam; Vikas Bhalla; Daniel Ukpong; Mahek Shah; Jeong Yun; D Lynn Morris; and Vincent M. Figueredo, M.D.

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Sex and race and/or ethnicity differences in patients undergoing radiofrequency ablation for Barrett's esophagus: results from the U.S. RFA Registry., Sarina Pasricha, Nan Li, William J. Bulsiewicz, Richard I. Rothstein, Anthony Infantolino, Atilla Ertan, Daniel S. Camara, Evan S. Dellon, George Triadafilopoulos, Charles J. Lightdale, Ryan D. Madanick, William D. Lyday, Raman V. Muthusamy, Bergein F. Overholt, and Nicholas J. Shaheen

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A Synthetic Lethality Screen Using a Focused siRNA Library to Identify Sensitizers to Dasatinib Therapy for the Treatment of Epithelial Ovarian Cancer., Harsh B Pathak, Yan Zhou, Geetika Sethi, Jeff Hirst, Russell J Schilder, Erica A Golemis, and Andrew K Godwin

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Isosorbide Mononitrate in Heart Failure with Preserved Ejection Fraction., Margaret M. Redfield, Kevin J. Anstrom, James A. Levine, Gabe A. Koepp, Barry A. Borlaug, Horng H. Chen, Martin M. LeWinter, Susan M. Joseph, Sanjiv J. Shah, Marc J. Semigran, G. Michael Felker, Robert T. Cole, Gordon R. Reeves, Ryan J. Tedford, W.H. Wilson Tang, Steven E. McNulty, Eric J. Velazquez, Monica R Shah, and Eugene Braunwald

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Tools for Economic Analysis of Patient Management Interventions in Heart Failure Cost-Effectiveness Model: A Web-based program designed to evaluate the cost-effectiveness of disease management programs in heart failure., Shelby D. Reed, Matthew P. Neilson, Matthew Gardner, Yanhong Li, Andrew H. Briggs, Daniel E E. Polsky, Felicia L. Graham, Margaret T. Bowers, Sara C. Paul, Bradi B. Granger, Kevin A. Schulman, David J. Whellan, Barbara Riegel, and Wayne C. Levy

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Immune Reconstitution but Persistent Activation After 48 Weeks of Antiretroviral Therapy in Youth With Pre-Therapy CD4 >350 in ATN 061., Bret J. Rudy, Bill G. Kapogiannis, Carol Worrell, Kathleen E. Squires, James Bethel, Su Li, Craig M. Wilson, Allison Agwu, Patricia Emmanuel, Georgine Price, Stephanie Hudey, Maureen M. Goodenow, and John W. Sleasman

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A Rare Cause of Obscure Occult Gastrointestinal Bleeding, Haroon Shahid, MD and Jason Korenblit, MD, MBA

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Effect of mycophenolate mofetil on the white blood cell count and the frequency of infection in systemic lupus erythematosus., Ananta Subedi, Laurence S. Magder, and Michelle Petri

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Emerging Novel Therapies for Heart Failure., Anthony M Szema, Sophia Dang, and Jonathan C Li

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Palbociclib in Hormone-Receptor-Positive Advanced Breast Cancer., Nicholas C Turner, Cynthia Huang Bartlett, and Massimo Cristofanilli

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Accuracy of Melena Identification on Physical Exam in Post Graduate Training – Implications of Level of Training, Medical Specialty, Rectal Exam Concordance and Appropriateness of Therapy, Richard M. Wu, MD, MPH; Eugene Han, MD; Andrew Dargan, MD; Cecilia Kelly, MD; and Mitchell Conn, MD, MBA

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Flattening filter-free accelerators: a report from the AAPM Therapy Emerging Technology Assessment Work Group., Ying Xiao, Stephen F Kry, Richard Popple, Ellen Yorke, Niko Papanikolaou, Sotirios Stathakis, Ping Xia, Saiful Huq, John Bayouth, James Galvin PhD, and Fang-Fang Yin

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Notching early repolarization pattern in inferior leads increases risk of ventricular tachyarrhythmias in patients with acute myocardial infarction: a meta-analysis., Zhiwei Zhang, Konstantinos P Letsas, Yajuan Yang, Panagiotis Korantzopoulos, Guangping Li, Gan-Xin Yan, and Tong Liu

Manuscripts from 2014

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Senile Cardiac Amyloidosis: An Undervalued Cause of Heart Failure., Toni Anne Alvarez de Venecia; Scott Blumhof; Daniel Ukpong; Marvin Lu; Claudia Nieves; and Vincent M. Figueredo, M.D.

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Estimation of daily interfractional larynx residual setup error after isocentric alignment for head and neck radiotherapy: quality assurance implications for target volume and organs-at-risk margination using daily CT on- rails imaging., Charles A Baron, Musaddiq J Awan, Abdallah S R Mohamed, Imad Akel, David I Rosenthal, G Brandon Gunn, Adam S Garden, Brandon A Dyer, Laurence Court, Parag R Sevak, Esengul Kocak-Uzel, and Clifton D Fuller

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Treatment of Duodenal Variceal Hemorrhage with Endoscopic Band Ligation, Tripti R. Chopade, MD; Jesse M. Civan, MD; Jonathan M. Fenkel, MD; Ali A. Siddiqui, MD; Ashish R. Gandhe, MD; and Dina L. Halegoua-De Marzio, MD

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Clinical Vignette: A Case of Successful Surgical Decortication for Empyema with Trapped Lung, in A Patient with Decompensated Cirrhosis, Tripti R. Chopade, MD; She-Yan Wong, MD; David A. Sass, MD; Scott W. Cowan, MD; and Jesse M. Civan, MD

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Update on ranolazine in the management of angina., J Nicolás Codolosa; Subroto Acharjee; and Vincent M. Figueredo, M.D.

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Underutilization of Statins and Aspirin Following Coronary Artery Bypass Graft Surgery, Kevin M. Curl, MD; Bryan Lebude, MD; Nicholas Ruggiero, MD; D L Fischman, MD; Andrew Rose, MD; Sulay Patel, MD; J. David Ogilby, MD; Paul Walinsky, MD; Babu Jasti, MD; and Michael P. Savage, MD

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Dipstick proteinuria is an independent predictor of high on treatment platelet reactivity in patients on clopidogrel, but not aspirin, admitted for major adverse cardiovascular events., Carlos D. Davila; Fernando Vargas; Kuan-Hsiang Gary Huang; Thomas Monaco; Anastasios Dimou; Janani Rangaswami; and Vincent M. Figueredo, M.D.

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Peripheral arterial disease, prevalence and cumulative risk factor profile analysis., Luis H. Eraso Jefferson Vascular Center, Departments of Medicine and Surgery, Thomas Jefferson University; Eri Fukaya; Emile R Mohler; Dawei Xie; Daohang Sha; and Jeffrey S Berger

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Understanding the power of perinatal events and metabolic status in childhood., Bonita Falkner and Julie Ingelfinger

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Decreased levels of BAG3 in a family with a rare variant and in idiopathic dilated cardiomyopathy., Arthur M Feldman, Rene L Begay, Tijana Knezevic, Valerie D Myers, Dobromir B Slavov, Weizhong Zhu, Katherine Gowan, Sharon L Graw, Kenneth L Jones, Douglas G Tilley, Ryan C Coleman, Paul Walinsky, Joseph Y Cheung, Luisa Mestroni, Kamel Khalili, and Mathew R G Taylor

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Rationale and design of the GUIDE-IT study: Guiding Evidence Based Therapy Using Biomarker Intensified Treatment in Heart Failure., G. Michael Felker, Tariq Ahmad, Kevin J. Anstrom, Kirkwood F. Adams, Lawton S. Cooper, Justin A. Ezekowitz, Mona Fiuzat, Nancy Houston-Miller, James L. Januzzi, Eric S. Leifer, Daniel B. Mark, Patrice Desvigne-Nickens, Gayle Paynter, Ileana L. Piña, David J. Whellan, and Christopher M. O'Connor

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Regular dipyridamole therapy produces sustained protection against cardiac ischemia-reperfusion injury: is it time to revisit PARIS?, Vincent M. Figueredo, M.D.; Chika Okusa; Kazuhiro Kaneda; Yoshitaka Inamura; and Masami Miyamae

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The new oral anticoagulants for the treatment of venous thromboembolism: a new paradigm shift in antithrombotic therapy., Taki Galanis, Gina Keiffer, and Geno J Merli

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Tachycardia mediated cardiomyopathy: pathophysiology, mechanisms, clinical features and management., Shuchita Gupta and Vincent M. Figueredo, M.D.

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Then and now: the progress in hepatitis B treatment over the past 20 years., Dina Halegoua-De Marzio and Hie-Won Hann

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Listing practices for Morbidly Obese Patients at Liver Transplant Centers in the United States, Dina Halegoua-De Marzio, MD; She-Yan Wong, MD; Jonathan M. Fenkel, MD; Cataldo Doria, MD, PhD; and David A. Sass, MD

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Enteral Nutrition Support for a Sarcopenia in End-Stage Liver Disease, Dina Halegoua-De Marzio, MD; She-Yan Wong, MD; Flavius Guglielmo, MD; and Jonathan M. Fenkel, MD

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A long-term study of the effects of antiviral therapy on survival of patients with HBV-associated hepatocellular carcinoma (HCC) following local tumor ablation., Hie-Won Hann, Robert Coben, Daniel Brown, Laurence Needleman, Ernest Rosato, Albert Min, Richard Hann, Kyong Bin Park, Stephen Dunn, and Anthony J. DiMarino

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Usefulness of Highly Sensitive AFP-L3 and DCP in Surveillance for Hepatocellular Carcinoma in Patients with a Normal Alpha-Fetoprotein, Hie-Won Hann, Dave Li, Hiroyuki Yamada, Shinji Satomura, Robert Coben, and Anthony J. DiMarino

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Molecular and functional identification of a mitochondrial ryanodine receptor in neurons., Regina Jakob, Gisela Beutner, Virendra K Sharma, Yuntao Duan, Robert A Gross, Stephen Hurst, Bong Sook Jhun, Jin O-Uchi, and Shey-Shing Sheu

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Wandering acute myocardial infarction., Kamal R. Joshi; D Lynn Morris; and Vincent M. Figueredo, M.D.

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Implementation of a Residency Twitter Account to Provide Curricular Enrichment, Bryan Lebude, MD; Subhashini Appulingam Sellers, MD; and Gretchen Diemer, MD, FACP

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Randomised clinical trial: Polyethylene glycol 3350 with sports drink vs. polyethylene glycol with electrolyte solution as purgatives for colonoscopy--the incidence of hyponatraemia., Rebecca Matro, Constantine Daskalakis, Dan Negoianu, Leo Katz, Cassandra Henry, Michael Share, and David Kastenberg

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Advances in the pathophysiology and treatment of heparin-induced thrombocytopenia., Steven E. McKenzie and Bruce S Sachais

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GATA3: a multispecific but potentially useful marker in surgical pathology: a systematic analysis of 2500 epithelial and nonepithelial tumors., Markku Miettinen, Peter McCue, Maarit Sarlomo-Rikala, Janusz Rys, Piotr Czapiewski, Krzysztof Wazny, Renata Langfort, Piotr Waloszczyk, Wojciech Biernat, Jerzy Lasota, and Zengfeng Wang

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The spectrum of eye disease in hospitalized adults living with HIV, 1995-2010., Christopher Miller; William Short, MD, MPH; Lorena Perez-Povis; Josephine Lontok; Christopher Fecarotta; Mengdan Liu; Jocelyn Sendecki; and Katherine Belden

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Evaluation of Echogenic Material on Transvenous Leads by Transesophageal Echocardiography in Patients with and without Lead-associated Endocarditis, Toshimasa Okabe, MD; Praveen Mehrotra, MD; Henry Siu, MD; and Arnold J. Greenspon, MD

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Adrenergic signaling regulates mitochondrial Ca2+ uptake through Pyk2-dependent tyrosine phosphorylation of the mitochondrial Ca2+ uniporter., Jin O-Uchi, Bong Sook Jhun, Shangcheng Xu, Stephen Hurst, Anna Raffaello, Xiaoyun Liu, Bing Yi, Huiliang Zhang, Polina Gross, Jyotsna Mishra, Alina Ainbinder, Sarah Kettlewell, Godfrey L Smith, Robert T Dirksen, Wang Wang, Rosario Rizzuto, and Shey-Shing Sheu

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Mitochondrial ion channels/transporters as sensors and regulators of cellular redox signaling., Jin O-Uchi, Shin-Young Ryu, Bong Sook Jhun, Stephen Hurst, and Shey-Shing Sheu

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Patient Characteristics and Predictors of Mortality Associated with Pericardial Decompression Syndrome, Rajesh Pradhan, MD; Toshimasa Okabe, MD; Kazuki Yoshida, MD; Dimitrios Angouras, MD; Matthew Decaro, MD; and Gregary D. Marhefka, MD

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Ventricular Septal Rupture in the Cardiac Catheterization Laboratory, Loheetha Ragupathi, MD; Xin Zhang, MD; and Gregary D. Marhefka, MD, FACP, FACC

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Induction of autophagy restores the loss of sevoflurane cardiac preconditioning seen with prolonged ischemic insult., Mayumi Shiomi; Masami Miyamae; Genzou Takemura; Kazuhiro Kaneda; Yoshitaka Inamura; Anna Onishi; Shizuka Koshinuma; Yoshihiro Momota; Toshiaki Minami; and Vincent M. Figueredo, M.D.

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Comparative effectiveness of less commonly used systemic monotherapies and common combination therapies for moderate to severe psoriasis in the clinical setting., Junko Takeshita, Shuwei Wang, Daniel B Shin, Kristina Callis Duffin, Gerald G Krueger, Robert E Kalb, Jamie D Weisman, Brian R Sperber, Michael B Stierstorfer, Bruce A Brod, Stephen M Schleicher, Andrew D Robertson, Kristin A Linn, Russell T Shinohara, Andrea B Troxel, Abby S Van Voorhees, and Joel M Gelfand

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Kallikrein family proteases KLK6 and KLK7 are potential early detection and diagnostic biomarkers for serous and papillary serous ovarian cancer subtypes., Ayala Tamir, Ushma Jag, Sreeja Sarojini, Craig Schindewolf, Takemi Tanaka, Rajendra Gharbaran, Hiren Patel, Anil Sood, Wei Hu, Ruzeen Patwa, Patrick Blake, Polina Chirina, Jin Oh Jeong, Heejin Lim, Andre Goy, Andrew Pecora, and K Stephen Suh

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The emerging role of oxylipins in thrombosis and diabetes., Benjamin E Tourdot, Intekhab Ahmed, and Michael Holinstat

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Optimal Duration of Holter Recordings: Is there Additional Yield from 48 Versus 24 Hours?, Amanda Trang, MD and Behzad B. Pavri, MD

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Adiponectin inhibits tumor necrosis factor-α-induced vascular inflammatory response via caveolin-mediated ceramidase recruitment and activation., Yajing Wang, Xiaoliang Wang, Wayne Bond Lau, Yuexing Yuan, David Booth, Jing-Jing Li, Rosario Scalia, Kyle Preston, Erhe Gao, Walter Koch, and Xin-Liang Ma

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Integrated guidance on the care of familial hypercholesterolaemia from the International FH Foundation., Gerald F Watts, Samuel Gidding, Anthony S Wierzbicki, Peter P Toth, Rodrigo Alonso, W Virgil Brown, Eric Bruckert, Joep Defesche, Khoo Kah Lin, Michael Livingston, Pedro Mata, Klaus G Parhofer, Frederick J Raal, Raul D Santos, Eric J G Sijbrands, William G Simpson, David R Sullivan, Andrey V Susekov, Brian Tomlinson, Albert Wiegman, Shizuya Yamashita, and John J P Kastelein

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Achieving high-value cardiac imaging: challenges and opportunities., David H Wiener

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Blau Syndrome, the prototypic auto-inflammatory granulomatous disease., Carine H Wouters, Anne Maes, Kevin P Foley, John Bertin, and Carlos D Rose

Manuscripts from 2013

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Long-term persistency and costs associated with the use of iron chelation therapies in the treatment of Sickle cell disease within Medicaid programs., Edward P Armstrong, Grant H Skrepnek, Medha Sasane, Susan M Snodgrass, and Samir K. Ballas

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Comparison of intravenous adenosine and intravenous regadenoson for the measurement of pressure-derived coronary fractional flow reserve., Pradeep Arumugham, Vincent M. Figueredo, Parul B Patel, and D Lynn Morris

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Listeria monocytogenes Cholecystitis: A Possible New Syndrome., Jackrapong Bruminhent, Timothy K Lynch, Jonathan Gefen, and Jerome Santoro

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Association between obesity and infarct size: insight into the obesity paradox., Beatriz Cepeda-Valery, MD; Leandro Slipczuk, MD; Vincent M. Figueredo, M.D.; Gregg S. Pressman; D Lynn Morris, MD; Carl J Lavie, MD; and Abel Romero-Corral, MD

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A multicenter, prospective, randomized comparison of a novel signal transmission capsule endoscope to an existing capsule endoscope., Eric H Choi, Klaus Mergener, Carol Semrad, Laurel Fisher, David R Cave, Milan Dodig, Carol Burke, Jonathan A Leighton, David Kastenberg, Peter Simpson, James Sul, Kanishka Bhattacharya, Roger Charles, Lauren Gerson, Luke Weber, Glenn Eisen, Warren Reidel, John J Vargo, Jamile Wakim-Fleming, and Simon K Lo

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De Novo Fibrillary Glomerulonephritis (FGN) in a Renal Transplant with Chronic Hepatitis C., E J Filippone, Christine Chmielewski, Rakesh Gulati, Eric Newman, and John Farber

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The case for intervention bias in the practice of medicine., Andrew J Foy and E J Filippone

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HDL-C: Does it matter? An update on novel HDL-directed pharmaco-therapeutic strategies., Ramprasad Gadi, Aman Amanullah, and Vincent M. Figueredo

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Ectopic Cushing's Syndrome from ACTH-Producing Pheochromocytoma, Susan Gerber, MD; Lawrence C. Kenyon, MD, PhD; Mary Kate McCullen; and Serge Jabbour, MD, FACP, FACE

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Presumed Familial Late-Onset Medullary Thyroid Cancer in a patient with a germline point mutation, c. 2304 G->T, in RET proto-oncogene codon 768: specific mutation may guide timing of prophylactic total thyroidectomy in affected family members, Susan Gerber, MD; Madalina Tuluc, MD, PhD; and Serge Jabbour, MD, FACP, FACE

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Nuclear translocation of cardiac G protein-Coupled Receptor kinase 5 downstream of select Gq-activating hypertrophic ligands is a calmodulin-dependent process., Jessica I Gold, Jeffrey S Martini, Jonathan Hullmann, Erhe Gao, J Kurt Chuprun, Linda Lee, Douglas G Tilley, Joseph E Rabinowitz, Julie Bossuyt, Donald M Bers, and Walter J. Koch

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Secondary membranous nephropathy associated with guillain-barré syndrome., Edward J Filippone, Mitul Kanzaria, Rodney Bell, Eric Newman, and John L Farber

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Combination of necroptosis and apoptosis inhibition enhances cardioprotection against myocardial ischemia-reperfusion injury., Shizuka Koshinuma, Masami Miyamae, Kazuhiro Kaneda, Junichiro Kotani, and Vincent M. Figueredo