Submissions from 2024
Ephrin-B2 Promotes Nociceptive Plasticity and Hyperalgesic Priming Through EphB2-MNK-eIF4E Signaling in Both Mice and Humans, Eric David, Muhammad Saad Yousuf, Hao-Ruei Mei, Ashita Jain, Sharada Krishnagiri, Hajira Elahi, Rupali Venkatesan, Kolluru Srikanth, Gregory Dussor, Matthew Dalva, and Theodore Price
Dopamine Release Neuroenergetics in Mouse Striatal Slices, Msema Msackyi, Yuanxin Chen, Wangchen Tsering, Ninghan Wang, and Hui Zhang
Automated Seizure Detection Based on State-Space Model Identification, Zhuo Wang, Michael Sperling, Dale Wyeth, and Allon Guez
Submissions from 2023
G Protein-Coupled Receptor Kinase-2 (GRK-2) Controls Exploration Through Neuropeptide Signaling in Caenorhabditis Elegans, Kristen Davis, Christo Mitchell, Olivia Weissenfels, Jihong Bai, David M. Raizen, Michael Ailion, and Irini Topalidou
MAxSIM: Multi-Angle-Crossing Structured Illumination Microscopy With Height-Controlled Mirror for 3D Topological Mapping of Live Cells, Pedro Felipe Gardeazabal Rodriguez, Yigal Lilach, Abhijit Ambegaonkar, Teresa Vitali, Haani Jafri, Hae Won Sohn, Matthew B. Dalva, Susan Pierce, and Inhee Chung
Neuroanatomical and Neurochemical Effects of Prolonged Social Isolation in Adult Mice, Vibol Heng, Michael Zigmond, and Richard Jay Smeyne
Dissecting the Daily Feeding Pattern: Peripheral CLOCK/CYCLE Generate the Feeding/Fasting Episodes and Neuronal Molecular Clocks Synchronize Them, Akiko Maruko, Koichi M Iijima, and Kanae Ando
Association Between Metabolic Syndrome and Stroke: A Population Based Cohort Study, Amir Moghadam-Ahmadi, Narjes Soltani, Fatemeh Ayoobi, Zahra Jamali, Tabandeh Sadeghi, Nazanin Jalali, Alireza Vakilian, Mohammad Amin Lotfi, and Parvin Khalili
Membrane Compression by Synaptic Vesicle Exocytosis Triggers Ultrafast Endocytosis, Tyler H Ogunmowo, Haoyuan Jing, Sumana Raychaudhuri, Grant F Kusick, Yuuta Imoto, Shuo Li, Kie Itoh, Ye Ma, Haani Jafri, Matthew B. Dalva, Edwin R Chapman, Taekjip Ha, Shigeki Watanabe, and Jian Liu
Submissions from 2022
Tunable Action Potential Repolarization Governed by Kv3.4 Channels in Dorsal Root Ganglion Neurons., Tyler D. Alexander, Tanziyah Muqeem, Lianteng Zhi, Stephen R. Tymanskyj, and Manuel Covarrubias
Response of Astrocyte Subpopulations Following Spinal Cord Injury, R Vivian Allahyari, Nicolette M Heinsinger, Daniel Hwang, David A Jaffe, Javad Rasouli, Stephanie Shiers, Samantha J Thomas, Theodore J Price, A M Rostami, and Angelo C Lepore
Astrocyte-secreted chordin-like 1 regulates spine density after ischemic injury, Elena Blanco-Suarez and Nicola J Allen
Cryo-EM Structure of the Human Kv3.1 Channel Reveals Gating Control by the Cytoplasmic T1 Domain, Gamma Chi, Qiansheng Liang, Akshay Sridhar, John B Cowgill, Kasim Sader, Mazdak Radjainia, Pu Qian, Pablo Castro-Hartmann, Shayla Venkaya, Nanki Kaur Singh, Gavin McKinley, Alejandra Fernandez-Cid, Shubhashish M M Mukhopadhyay, Nicola A Burgess-Brown, Lucie Delemotte, Manuel Covarrubias, and Katharina L Dürr
Breakdown of the Central Synapses in C9orf72-Linked ALS/FTD, Layla T. Ghaffari, Davide Trotti, Aaron R. Haeusler, and Brigid K Jensen
Nanoscale rules governing the organization of glutamate receptors in spine synapses are subunit specific, Martin Hruska, Rachel E Cain, and Matthew B Dalva
Mutant LRRK2 in lymphocytes regulates neurodegeneration via IL-6 in an inflammatory model of Parkinson's disease, Elena Kozina, Matthew D. Byrne, and Richard Jay Smeyne
Transcriptional Profiles in Olfactory Pathway-Associated Brain Regions of African Green Monkeys: Associations With Age and Alzheimer’s Disease Neuropathology, Jacob D Negrey, Dorothy L Dobbins, Timothy D Howard, Karin E Borgmann-Winter, C G Hahn, Sergey Kalinin, Douglas L Feinstein, Suzanne Craft, Carol A Shively, and Thomas C Register
Rotenone induces regionally distinct α-synuclein protein aggregation and activation of glia prior to loss of dopaminergic neurons in C57Bl/6 mice, Savannah M Rocha, Collin M Bantle, Tawfik Aboellail, Debotri Chatterjee, Richard Jay Smeyne, and Ronald B Tjalkens
Selective axonal transport through branch junctions is directed by growth cone signaling and mediated by KIF1/kinesin-3 motors., Stephen R. Tymanskyj, Bridget M. Curran, and Le Ma
A mouse model with widespread expression of the C9orf72-linked glycine-arginine dipeptide displays non-lethal ALS/FTD-like phenotypes, Brandie Morris Verdone, Maria Elena Cicardi, Xinmei Wen, Sindhu Sriramoji, Katelyn Russell, Shashirekha S Markandaiah, Brigid K Jensen, Karthik Krishnamurthy, Aaron R. Haeusler, Piera Pasinelli, and Davide Trotti
Submissions from 2021
Neuronal Nsun2 deficiency produces tRNA epitranscriptomic alterations and proteomic shifts impacting synaptic signaling and behavior., J Blaze, A Navickas, H L Phillips, S Heissel, A Plaza-Jennings, S Miglani, H Asgharian, M Foo, C D Katanski, C P Watkins, Z T Pennington, B Javidfar, S Espeso-Gil, B Rostandy, H Alwaseem, C G Hahn, H Molina, D J Cai, T Pan, W D Yao, H Goodarzi, F Haghighi, and S Akbarian
CalDAG-GEFI mediates striatal cholinergic modulation of dendritic excitability, synaptic plasticity and psychomotor behaviors., Jill R. Crittenden, Shenyu Zhai, Magdalena Sauvage, Takashi Kitsukawa, Eric Burguière, Morgane Thomsen, Hui Zhang, Cinzia Costa, Giuseppina Martella, Veronica Ghiglieri, Barbara Picconi, Karen A. Pescatore, Ellen M. Unterwald, Walker S. Jackson, David E. Housman, S. Barak Caine, David Sulzer, Paolo Calabresi, Anne C. Smith, D. James Surmeier, and Ann M. Graybiel
Conservation and Innovation: Versatile Roles for LRP4 in Nervous System Development., Alison T. DePew and Timothy J. Mosca
A high affinity, partial antagonist effect of 3,4-diaminopyridine mediates action potential broadening and enhancement of transmitter release at NMJs, Kristine S Ojala, Scott P Ginebaugh, Man Wu, Evan W Miller, Gloria Ortiz, Manuel Covarrubias, and Stephen D Meriney
Rapid Decline in Telestroke Consults in the Setting of COVID-19., Syed O. Shah., Robin Dharia, Jaime Stazi, Maureen DePrince, and Robert H. Rosenwasswer
Infection and Risk of Parkinson's Disease, Richard Jay Smeyne, Alastair J Noyce, Matthew D. Byrne, Rodolfo Savica, and Connie Marras
Treatment-Specific Hippocampal Subfield Volume Changes With Antidepressant Medication or Cognitive-Behavior Therapy in Treatment-Naive Depression., Hua-Hsin Tai, Jungho Cha, Faezeh Vedaei, Boadie W Dunlop, W Edward Craighead, Helen S Mayberg, and Ki Sueng Choi
The Ephb2 Receptor Uses Homotypic, Head-to-Tail Interactions within Its Ectodomain as an Autoinhibitory Control Mechanism, Yan Xu, Dorothea Robev, Nayanendu Saha, Bingcheng Wang, Matthew B. Dalva, Kai Xu, Juha P. Himanen, and Dimitar B. Nikolov
Submissions from 2020
A Crucial Role for the Protein Quality Control System in Motor Neuron Diseases., Riccardo Cristofani, Valeria Crippa, Maria Elena Cicardi, Barbara Tedesco, Veronica Ferrari, Marta Chierichetti, Elena Casarotto, Margherita Piccolella, Elio Messi, Mariarita Galbiati, Paola Rusmini, and Angelo Poletti
Combination of a Gellan Gum-Based Hydrogel With Cell Therapy for the Treatment of Cervical Spinal Cord Injury, Eduardo D Gomes, Biswarup Ghosh, Rui Lima, Miguel Goulão, Tiago Moreira-Gomes, Joana Martins-Macedo, Mark W Urban, Megan C Wright, Jeffrey M Gimble, Nuno Sousa, Nuno A Silva, Angelo C Lepore, and António J Salgado
Facial grimace testing as an assay of neuropathic pain-related behavior in a mouse model of cervical spinal cord injury., Nicolette M Heinsinger, Gabrielle Spagnuolo, R Vivian Allahyari, Simon Galer, Tyler Fox, David A Jaffe, Samantha J Thomas, Lorraine Iacovitti, and Angelo C Lepore
Synaptic dysfunction induced by glycine-alanine dipeptides in C9orf72-ALS/FTD is rescued by SV2 replenishment., Brigid K Jensen, Martin H Schuldi, Kevin McAvoy, Katelyn A Russell, Ashley Boehringer, Bridget M Curran, Karthik Krishnamurthy, Xinmei Wen, Thomas Westergard, Le Ma, Aaron R. Haeusler, Dieter Edbauer, Piera Pasinelli, and Davide Trotti
Antagonistic Regulation of Circadian Output and Synaptic Development by JETLAG and the DYSCHRONIC-SLOWPOKE Complex, Angelique Lamaze, James E.C. Jepson, Oghenerukevwe Akpoghiran, and Kyunghee Koh
COVID-19-associated CNS Demyelinating Diseases, Dhanashri Miskin, MD
Sleep Induction by Mechanosensory Stimulation in Drosophila., Arzu Öztürk-Çolak, Sho Inami, Joseph R. Buchler, Patrick D. McClanahan, Andri Cruz, Christopher Fang-Yen, and Kyunghee Koh
COVID-19 and possible links with Parkinson's disease and parkinsonism: from bench to bedside, David Sulzer, Angelo Antonini, Valentina Leta, Anna Nordvig, Richard Jay Smeyne, James E Goldman, Osama Al-Dalahmah, Luigi Zecca, Alessandro Sette, Luigi Bubacco, Olimpia Meucci, Elena Moro, Ashley S Harms, Yaqian Xu, Stanley Fahn, and K Ray Chaudhuri
Positive surface charge of GluN1 N-terminus mediates the direct interaction with EphB2 and NMDAR mobility., Halley R. Washburn, Nan L. Xia, Wei Zhou, Yu-Ting Mao, and Matthew B. Dalva
Submissions from 2019
The Tenets of Teneurin: Conserved Mechanisms Regulate Diverse Developmental Processes in the Drosophila Nervous System, Alison T. DePew, Michael A. Aimino, and Timothy J. Mosca
Ephrin-B3 controls excitatory synapse density through cell-cell competition for EphBs., Nathan T. Henderson, Sylvain J. Le Marchand, Martin Hruska, Simon Hippenmeyer, Liqun Luo, and Matthew B. Dalva
Understanding the axonal response to injury by in vivo imaging in the mouse spinal cord: A tale of two branches., Binhai Zheng, Ariana O Lorenzana, and Le Ma
Submissions from 2018
Evolution of Cortical Neurogenesis in Amniotes Controlled by Robo Signaling Levels., Adrián Cárdenas, Ana Villalba, Camino de Juan Romero, Esther Picó, Christina Kyrousi, Athanasia C Tzika, Marc Tessier-Lavigne, Le Ma, Micha Drukker, Silvia Cappello, and Víctor Borrell
Representing diversity in the dish: Using patient-derived in vitro models to recreate the heterogeneity of neurological disease, Layla T. Ghaffari, Alexander Starr, Andrew T. Nelson, and Rita Sattler
Synaptic nanomodules underlie the organization and plasticity of spine synapses., Martin Hruska, Nathan T. Henderson, Sylvain J. Le Marchand, Haani Jafri, and Matthew B. Dalva
Regional microglia are transcriptionally distinct but similarly exacerbate neurodegeneration in a culture model of Parkinson's disease., Eric Wildon Kostuk, Jingli Cai, and Lorraine Iacovitti
MAP7 regulates axon morphogenesis by recruiting kinesin-1 to microtubules and modulating organelle transport., Stephen R. Tymanskyj, Benjamin Yang, Kristen J. Verhey, and Le Ma
Propofol inhibits the voltage-gated sodium channel NaChBac at multiple sites., Yali Wang, Elaine Yang, Marta M. Wells, Vasyl Bondarenko, Kellie Woll, Vincenzo Carnevale, Daniele Granata, Michael L. Klein, Roderic G. Eckenhoff, William P. Dailey, Manuel Covarrubias, Pei Tang, and Yan Xu
Propofol inhibits prokaryotic voltage-gated Na+ channels by promoting activation-coupled inactivation, Elaine Yang, Daniele Granata, Roderic G. Eckenhoff, Vincenzo Carnevale, and Manuel Covarrubias
Genome-wide profiling reveals functional diversification of ∆FosB gene targets in the hippocampus of an Alzheimer's disease mouse model., Jason C. You, Gabriel S. Stephens, Chia-Hsuan Fu, Xiaohong Zhang, Yin Liu, and Jeannie Chin
A-Type KV Channels in Dorsal Root Ganglion Neurons: Diversity, Function, and Dysfunction, Benjamin M. Zemel, David M. Ritter, Manuel Covarrubias, and Tanziyah Muqeem
Submissions from 2017
Rabies screen reveals GPe control of cocaine-triggered plasticity., Kevin T. Beier, Christina K. Kim, Paul Hoerbelt, Lin Wai Hung, Boris D. Heifets, Katherine E. DeLoach, Timothy J. Mosca, Sophie Neuner, Karl Deisseroth, Liqun Luo, and Robert C. Malenka
A delayed h3k27me3 accumulation after DNA replication of embryonic stem cells opens chromatin for lineage specific transcription factors to bind and initiate differentiation, Jingli Cai, Svetlana Petruk, Robyn Sussman, Sina K. Kovermann, Samantha Mariani, Bruno Calabretta, Steven B McMahon, Hugh W. Brock, Lorraine Iacovitti, and Alexander Mazo
Harnessing the power of cell transplantation to target respiratory dysfunction following spinal cord injury., Brittany A. Charsar, Mark W. Urban, and Angelo C. Lepore
ΔFosB Regulates Gene Expression and Cognitive Dysfunction in a Mouse Model of Alzheimer's Disease., Brian F Corbett, Jason C You, Xiaohong Zhang, Mark S Pyfer, Umberto Tosi, Daniel M Iascone, Iraklis Petrof, Anupam Hazra, Chia-Hsuan Fu, Gabriel S Stephens, Annie Ashok, Suzan Aschmies, Lijuan Zhao, Eric J Nestler, and Jeannie Chin
Regulation of sleep plasticity by a thermo-sensitive circuit in Drosophila., Angelique Lamaze, Arzu Öztürk-Çolak, Robin Fischer, Nicolai Peschel, Kyunghee Koh, and James E.C. Jepson
Identification of octopaminergic neurons that modulate sleep suppression by male sex drive., Daniel R. Machado, Dinis Afonso, Alexandra R. Kenny, Arzu Öztürk-Çolak, Emilia H. Moscato, Benjamin Mainwaring, Matthew Kayser, and Kyunghee Koh
Presynaptic LRP4 promotes synapse number and function of excitatory CNS neurons., Timothy J. Mosca, David J. Luginbuhl, Irving E. Wang, and Liqun Luo
MAP7 Regulates Axon Collateral Branch Development in Dorsal Root Ganglion Neurons., Stephen R Tymanskyj, Benjamin Yang, Aditi Falnikar, Angelo C Lepore, and Le Ma
Pathogenic determinants and mechanisms of ALS/FTD linked to hexanucleotide repeat expansions in the C9orf72 gene., Xinmei Wen, Thomas Westergard, Piera Pasinelli, and Davide Trotti
A Role for AnkyrinG in Maturation and Maintenance of the Nodes of Ranvier., Benjamin Yang, Bridget M. Curran, and Stephen R. Tymanskyj
Epigenetic suppression of hippocampal calbindin-D28k by ΔFosB drives seizure-related cognitive deficits., Jason C. You, Kavitha Muralidharan, Jin W. Park, Iraklis Petrof, Mark S. Pyfer, Brian F. Corbett, John J. LaFrancois, Yi Zheng, Xiaohong Zhang, Carrie A. Mohila, Daniel Yoshor, Robert A. Rissman, Eric J. Nestler, Helen E. Scharfman, and Jeannie Chin
Calcineurin Dysregulation Underlies Spinal Cord Injury-Induced K(+) Channel Dysfunction in DRG Neurons., Benjamin M. Zemel, Tanziyah Muqeem, Eric V. Brown, Miguel Goulão, Mark W Urban, Stephen R. Tymanskyj, Angelo C. Lepore, and Manuel Covarrubias
Submissions from 2016
Tau phosphorylation at Alzheimer's disease-related Ser356 contributes to tau stabilization when PAR-1/MARK activity is elevated., Kanae Ando, Mikiko Oka, Yosuke Ohtake, Motoki Hayashishita, Sawako Shimizu, Shin-Ichi Hisanaga, and Koichi M. Iijima
Closed-state inactivation involving an internal gate in Kv4.1 channels modulates pore blockade by intracellular quaternary ammonium ions., Jeffrey D. Fineberg, Tibor G. Szanto, Gyorgy Panyi, and Manuel Covarrubias
Stabilization of Microtubule-Unbound Tau via Tau Phosphorylation at Ser262/356 by Par-1/MARK Contributes to Augmentation of AD-Related Phosphorylation and Aβ42-Induced Tau Toxicity., Kanae Iijima-Ando, Akiko Maruko-Otake, Yosuke Ohtake, Motoki Hayashishita, Michiko Sekiya, and Koichi M Iijima
Dcc Mediates Functional Assembly of Peripheral Auditory Circuits., Young J Kim, Sheng-Zhi Wang, Stephen Tymanskyj, Le Ma, Huizhong W Tao, and Li I Zhang
Assessment of the Effects of MPTP and Paraquat on Dopaminergic Neurons and Microglia in the Substantia Nigra Pars Compacta of C57BL/6 Mice., Richard Jay Smeyne, Charles B. Breckenridge, Melissa Beck, Yun Jiao, Mark T. Butt, Jeffrey C. Wolf, Dan Zadory, Daniel J. Minnema, Nicholas C. Sturgess, Kim Z. Travis, Andrew R. Cook, Lewis L. Smith, and Philip A. Botham
Submissions from 2015
TARANIS Functions with Cyclin A and Cdk1 in a Novel Arousal Center to Control Sleep in Drosophila., Dinis J.S. Afonso, Die Liu, Daniel R. Machado, Huihui Pan, James E.C. Jepson, Dragana Rogulja, and Kyunghee Koh
Loss of VGLUT3 Produces Circadian-Dependent Hyperdopaminergia and Ameliorates Motor Dysfunction and l-Dopa-Mediated Dyskinesias in a Model of Parkinson's Disease., Christopher B. Divito, Kathy Steece-Collier, Daniel T. Case, Sean-Paul G. Williams, Jennifer A. Stancati, Lianteng Zhi, Maria E. Rubio, Caryl E. Sortwell, Timothy J. Collier, David Sulzer, Robert H. Edwards, Hui Zhang, and Rebecca P. Seal
Positive Allosteric Modulation of Kv Channels by Sevoflurane: Insights into the Structural Basis of Inhaled Anesthetic Action., Qiansheng Liang, Warren D Anderson, Shelly T Jones, Caio S Souza, Juliana M Hosoume, Werner Treptow, and Manuel Covarrubias
Human iPS cell-derived astrocyte transplants preserve respiratory function after spinal cord injury., Ke Li, Elham Javed, Daniel Scura, Tamara J. Hala, Suneil Seetharam, Aditi Falnikar, Jean-Philippe Richard, Ashley Chorath, Nicholas J. Maragakis, Megan C. Wright, and Angelo C. Lepore
Interactions of L-3,5,3′-triiodothyronine, allopregnanolone, and ivermectin with the GABAA receptor: Evidence for overlapping intersubunit binding modes, Thomas Westergard, Reza Salari, Joseph V. Martin, and Grace Brannigan
Submissions from 2014
Persistent At-Level Thermal Hyperalgesia and Tactile Allodynia Accompany Chronic Neuronal and Astrocyte Activation in Superficial Dorsal Horn following Mouse Cervical Contusion Spinal Cord Injury., Jaime L Watson, Tamara J Hala, Rajarshi Putatunda, Daniel Sannie, and Angelo C Lepore
Submissions from 2013
Serotonergic innervation and serotonin receptor expression of NPY-producing neurons in the rat lateral and basolateral amygdaloid nuclei., M Bonn, A Schmitt, K-P Lesch, E J Van Bockstaele, and E Asan
Synchronous and asynchronous theta and gamma activity during episodic memory formation., John F Burke, Kareem A Zaghloul, Joshua Jacobs, Ryan B Williams, Michael R Sperling, Ashwini D Sharan, and Michael J Kahana
Acute activation, desensitization and smoldering activation of human acetylcholine receptors., Barbara Campling, M.D., FRCPC; Alexander Kuryatov; and Jon Lindstrom
Expression of c-fos in hilar mossy cells of the dentate gyrus in vivo., Aine M Duffy, Michael J Schaner, Jeannie Chin, and Helen E Scharfman
Genetic and anatomical basis of the barrier separating wakefulness and anesthetic-induced unresponsiveness., William J Joiner, Eliot B Friedman, Hsiao-Tung Hung, Kyunghee Koh, Mallory Sowcik, Amita Sehgal, and Max B Kelz
Exploring volatile general anesthetic binding to a closed membrane-bound bacterial voltage-gated sodium channel via computation., S G Raju, Annika F Barber, David N LeBard, Michael L Klein, and Vincenzo Carnevale
Defects in synapse structure and function precede motor neuron degeneration in Drosophila models of FUS-related ALS., Mohammad Shahidullah, Sylvain J Le Marchand, Hong Fei, Jiaming Zhang, Udai Bhan Pandey, Matthew B. Dalva, Piera Pasinelli, and Irwin B. Levitan
Choline transporter-like protein 4 (CTL4) links to non-neuronal acetylcholine synthesis., Pingfang Song; Stephen S Rekow; Corey-Ayne Singleton; Harmanjatinder S Sekhon; Gregory A Dissen; Minerva Zhou; Barbara Campling, M.D., FRCPC; Jon Lindstrom; and Eliot R Spindel
Submissions from 2012
Degeneration of phrenic motor neurons induces long-term diaphragm deficits following mid-cervical spinal contusion in mice., Charles Nicaise, Rajarshi Putatunda, Tamara J Hala, Kathleen A Regan, David M Frank, Jean-Pierre Brion, Karelle Leroy, Roland Pochet, Megan C Wright, and Angelo C Lepore
Submissions from 2011
Human glial-restricted progenitor transplantation into cervical spinal cord of the SOD1 mouse model of ALS., Angelo C Lepore, John O'Donnell, Andrew S Kim, Timothy Williams, Alicia Tuteja, Mahendra S Rao, Linda L Kelley, James T Campanelli, and Nicholas J Maragakis
Human glial-restricted progenitor transplantation into cervical spinal cord of the SOD1 mouse model of ALS., Angelo C Lepore, John O'Donnell, Andrew S Kim, Timothy Williams, Alicia Tuteja, Mahendra S Rao, Linda L Kelley, James T Campanelli, and Nicholas J Maragakis
SLOB, a SLOWPOKE channel binding protein, regulates insulin pathway signaling and metabolism in Drosophila., Amanda L. Sheldon, Jiaming Zhang, Hong Fei, and Irwin B Levitan
