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Manuscripts from 2024

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Combination Treatment of Biochanin A and Atorvastatin Alters Mitochondrial Bioenergetics, Modulating Cell Metabolism and Inducing Cell Cycle Arrest in Pancreatic Cancer Cells, Vilas Desai, Satya Murthy Tadinada, Hoora Shaghaghi, Ross Summer, James C.K. Lai, and Alok Bhushan

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The Dual-Targeted Fusion Inhibitor Clofazimine Binds to the S2 Segment of the SARS-CoV-2 Spike Protein, Matthew Freidel, Pratiti Vakhariya, Shalinder Sardarni, and Roger Armen

Manuscripts from 2023

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A Longitudinal Observational Study of Medical Cannabis Use and Polypharmacy among Patients Presenting to Dispensaries in Pennsylvania, Emily R. Hajjar, Allison Herens, Erin L. Kelly, Kayla Madden, Jessica M. Lungen, and Brooke K. Worster

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Two-Pore Channel-2 and Inositol Trisphosphate Receptors Coordinate CA2+ Signals Between Lysosomes and the Endoplasmic Reticulum, Yu Yuan, Vikas Arige, Ryo Saito, Qianru Mu, Gabriela C. Brailoiu, Gustavo J.S. Pereira, Stephen R. Bolsover, Marco Keller, Franz Bracher, Christian Grimm, Eugen Brailoiu, Jonathan S. Marchant, David I. Yule, and Sandip Patel

Manuscripts from 2022

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A state-wide education program on opioid use disorder: influential community members' knowledge, beliefs, and opportunities for coalition development, Lindsey Hohmann, Haley Phillippe, Karen Marlowe, Ruth Jeminiwa, Natalie Hohmann, Salisa Westrick, Amanda Fowler, and Brent Fox

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Use of tocilizumab, remdesivir, and high-dose methylprednisolone prevents intubation in an ESRD patient with COVID-19 pneumonia, Ramzan Judge, Stephanie Kolaski, and Farhan Qadeer

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Effects of GLP-1 Receptor Agonists on Cardiovascular Outcomes in Patients With Type 2 Diabetes and Chronic Kidney Disease: A Systematic Review and Meta-Analysis, Michael Kelly, Jelena Lewis, Hindu Rao, Jessica Carter, Ivan Portillo, and Richard Beuttler

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Blood-Brain Barrier Disruption Mediated by FFA1 Receptor-Evidence Using Miniscope, Kristen L Lindenau, Jeffrey L Barr, Christopher R Higgins, Kevin T Sporici, Eugen Brailoiu, and G Cristina Brailoiu

Manuscripts from 2021

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Mapping major SARS-CoV-2 drug targets and assessment of druggability using computational fragment screening: Identification of an allosteric small-molecule binding site on the Nsp13 helicase., Matthew R Freidel and Roger S Armen

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Human Immunodeficiency Virus Type-1 (HIV-1) Transcriptional Regulation, Latency and Therapy in the Central Nervous System, Joseph Hokello, Adhikarimayum Lakhikumar Sharma, Priya Tyagi, Alok Bhushan, and Mudit Tyagi

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Incidence and Severity of Drug Interactions Before and After Switching Antiretroviral Therapy to Bictegravir/Emtricitabine/Tenofovir Alafenamide in Treatment-Experienced Patients., Jason J. Schafer, PharmD, MPH, BCPS, AAHIVP; Neha S Pandit; Agnes Cha; Emily Huesgen; Melissa Badowski; Elizabeth M Sherman; Jennifer Cocohoba; Ayako Shimada; and Scott W Keith

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CD44-targeted, indocyanine green-paclitaxel-loaded human serum albumin nanoparticles for potential image-guided drug delivery., Karthik Thangavel, Asha Lakshmikuttyamma, Chellappagounder Thangavel, and Sunday A. Shoyele

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Implementation of a Teaching Electronic Medical Record within Didactic Instruction Using a Drug Information Question Assignment., Jacqueline Wasynczuk and Amy H Sheehan

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Managing Polypharmacy in Older Adults with Cancer Across Different Healthcare Settings., Andrew Whitman; Paige Erdeljac; Caroline Jones; Nicole Pillarella; and Ginah Nightingale PharmD, BCOP

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Faculty writing: A collaborative approach to producing manuscripts., Jennifer Wilson, Pamela Walter, Shoshana Sicks, and Elena Umland

Manuscripts from 2020

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1-Chromonyl-5-Imidazolylpentadienone Demonstrates Anti-Cancer Action against TNBC and Exhibits Synergism with Paclitaxel, Karan Modi, Scott Lawson, Guanglin Chen, Deepthi Tumuluri, Inga Rekhtman, Michael Kurtz, G Cristina Brailoiu, Qiao-Hong Chen, and Ashakumary Lakshmikuttyamma

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Heat Shock Protein 90 (Hsp90)-Inhibitor-Luminespib-Loaded-Protein-Based Nanoformulation for Cancer Therapy, Ankit K. Rochani; Sivakumar Balasubramanian; Aswathy Ravindran Girija; Toru Maekawa; Gagan Kaushal, PhD; and D Sakthi Kumar

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LC-MS based stability-indicating method for studying the degradation of lonidamine under physical and chemical stress conditions, Ankit K. Rochani, Margaret A. Wheatley, Brian Oeffinger, John R. Eisenbrey, and Gagan Kaushal

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Flavonoids and Other Polyphenols Act as Epigenetic Modifiers in Breast Cancer., Priyanga Selvakumar, Aja Badgeley, Paige Murphy, Hina Anwar, Urvashi Sharma, Katharine Lawrence, and Ashakumary Lakshmikuttyamma

Manuscripts from 2019

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Choline Is an Intracellular Messenger Linking Extracellular Stimuli to IP3-Evoked Ca2+ Signals through Sigma-1 Receptors, Eugen Brailoiu, Sumita Chakraborty, G. Cristina Brailoiu, Pingwei Zhao, Jeffrey L. Barr, Marc A. Ilies, Ellen M. Unterwald, Mary E. Abood, and Colin W. Taylor

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Codelivery of Genistein and miRNA-29b to A549 Cells Using Aptamer-Hybrid Nanoparticle Bioconjugates., Koita Sacko, Karthik Thangavel, and Sunday A. Shoyele

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Changes in Body Mass Index and Atherosclerotic Disease Risk Score After Switching From Tenofovir Disoproxil Fumarate to Tenofovir Alafenamide., Jason J. Schafer, Kaitlin N. Sassa, Jaclyn R. O'Connor, Ayako Shimada, Scott W. Keith, and Joseph A. DeSimone

Manuscripts from 2018

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Formulation, characterization and evaluation of morusin loaded niosomes for potentiation of anticancer therapy, Srishti Agarwal, M. Sheikh Mohamed, Sreejith Raveendran, Ankit K. Rochani, Toru Maekawa, and D. Sakthi Kumar

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Effects of Platelet-Activating Factor on Brain Microvascular Endothelial Cells., Eugen Brailoiu, Christine L. Barlow, Servio H. Ramirez, Mary E. Abood, and G. Cristina Brailoiu

Manuscripts from 2017

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Mechanisms of modulation of brain microvascular endothelial cells function by thrombin., Eugen Brailoiu, Megan M. Shipsky, Guang Yan, Mary E. Abood, and G. Cristina Brailoiu

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Natural Bioactive Compounds: Alternative Approach to the Treatment of Glioblastoma Multiforme, Vilas Desai and Alok Bhushan

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Medication Complications in Extracorporeal Membrane Oxygenation., Ami G. Shah, Michelle Peahota, Brandi Thoma, and Walter K. Kraft

Manuscripts from 2016

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Aptamer-hybrid nanoparticle bioconjugate efficiently delivers miRNA-29b to non-small-cell lung cancer cells and inhibits growth by downregulating essential oncoproteins., Maryna Perepelyuk, Christina Maher, Ashakumary Lakshmikuttyamma, and Sunday A. Shoyele

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A randomized placebo-controlled pilot study of the efficacy and safety of D-cycloserine in people with chronic back pain., Thomas J. Schnitzer, Souraya Torbey, Kristi Herrmann, Gagan Kaushal, Renita Yeasted, and A. Vania Apkarian

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Polypharmacy and potentially inappropriate medication use in geriatric oncology., Manvi Sharma; Kah Poh Loh; Ginah Nightingale PharmD, BCOP; Supriya G. Mohile; and Holly M. Holmes

Manuscripts from 2015

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Mechanisms of activation of nucleus accumbens neurons by cocaine via sigma-1 receptor-inositol 1,4,5-trisphosphate-transient receptor potential canonical channel pathways., Jeffrey L. Barr, Elena Deliu, Gabriela Cristina Brailoiu, Pingwei Zhao, Guang Yan, Mary E. Abood, Ellen M. Unterwald, and Eugen Brailoiu

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Irisin evokes bradycardia by activating cardiac-projecting neurons of nucleus ambiguus., Eugen Brailoiu, Elena Deliu, Romeo A Sporici, and Gabriela Cristina Brailoiu

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Evaluation of a pharmacist-led medication assessment used to identify prevalence of and associations with polypharmacy and potentially inappropriate medication use among ambulatory senior adults with cancer., Ginah Nightingale, Emily Hajjar, Kristine Swartz, Jocelyn Andrel-Sendecki, and Andrew Chapman

Manuscripts from 2014

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Outcomes of Third-Year Pharmacy Students Using Technology for Instruction in an Infectious Diseases Elective Course, Joanna Headley, PharmD, Candidate 2015; Bhavik Shah, PharmD, BCPS, AAHIVP; and Jason J. Schafer, PharmD, MPH, BCPS, AAHIVP

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Clinical consequences of polypharmacy in elderly., Robert L Maher, Joseph Hanlon, and Emily Hajjar

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Cost-effectiveness of a community-integrated home-based depression intervention in older African Americans., Laura T. Pizzi, Eric Jutkowitz, Kevin D Frick, Dong-Churl Suh, Katherine M Prioli, and Laura N Gitlin

Manuscripts from 2013

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Fibroblast growth factor-2 (FGF2) and syndecan-1 (SDC1) are potential biomarkers for putative circulating CD15+/CD30+ cells in poor outcome Hodgkin lymphoma patients., Rajendra Gharbaran, Andre Goy, Takemi Tanaka, Jongwhan Park, Chris Kim, Nafis Hasan, Swathi Vemulapalli, Sreeja Sarojini, Madalina Tuluc, Kip Nalley, Pritish Bhattacharyya, Andrew Pecora, and K Stephen Suh

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Identification of distant drug off-targets by direct superposition of binding pocket surfaces., Marcel Schumann and Roger S Armen

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Clevidipine for Acute Blood Pressure Management in the Neurological Intensive Care Unit, Dorota K. Szarlej, PharmD; Jessica L. McKeon, PharmD; Akta S. Patel, PharmD, BCPS; and Amber King

Manuscripts from 2012

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The Use of Glucarpidase in an Open-Label Treatment Protocol as Adjunctive Treatment for a Patient with Delayed Methotrexate Elimination, Cheryl A. Abbas, PharmD and Anne Marie Valorie-Oberle, BS, PharmD, BCOP

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Heart Failure Transition of Care Program: The Pharmacist’s role in reducing readmissions, Joseph Favatella, PharmD Candidate 2013 and Joanne Heil, PharmD, BCPS

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Intracranial hypertension secondary to psychogenic polydipsia., Vanessa M Gleason and Niels D Martin

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Treatment options for vasomotor symptoms in menopause: focus on desvenlafaxine., Elena M Umland and Laura Falconieri

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Interprofessional Education in Didactic and Experiential Settings at the Jefferson School of Pharmacy, Elena M. Umland, Cynthia A. Sanoski, Emily R. Hajjar, and Bhavik Shah

Manuscripts from 2011

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An evidence-based review of fat modifying supplemental weight loss products., Amy M Egras, William R Hamilton, Thomas L Lenz, and Michael S Monaghan

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Thioaptamer conjugated liposomes for tumor vasculature targeting., Aman P Mann, Rohan C Bhavane, Anoma Somasunderam, Brenda Liz Montalvo-Ortiz, Ketan B Ghaghada, David Volk, René Nieves-Alicea, K Stephen Suh, Mauro Ferrari, Ananth Annapragada, David G Gorenstein, and Takemi Tanaka

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Differential subcellular distribution of rat brain dopamine receptors and subtype-specific redistribution induced by cocaine., Pamela J Voulalas, John Schetz, and Ashiwel S Undieh

Manuscripts from 2010

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Antidepressant stimulation of CDP-diacylglycerol synthesis does not require monoamine reuptake inhibition, Marwa A. Aboukhatwa and Ashiwel S. Undieh

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The role of transdermal estrogen sprays and estradiol topical emulsion in the management of menopause-associated vasomotor symptoms., Amy M Egras and Elena Umland

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Building capacity for public and population health research in Africa: the consortium for advanced research training in Africa (CARTA) model., Alex C Ezeh, Chimaraoke O Izugbara, Caroline W Kabiru, Sharon Fonn, Kathleen Kahn, Lenore Manderson, Ashiwel S. Undieh, Akinyinka Omigbodun, and Margaret Thorogood

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Troglitazone stimulates beta-arrestin-dependent cardiomyocyte contractility via the angiotensin II type 1A receptor., Douglas G G. Tilley, Anny D. Nguyen, and Howard A. Rockman

Manuscripts from 2009

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Transcriptional regulation of cytokine function in airway smooth muscle cells., Deborah Clarke, Gautam Damera, Maria B. Sukkar, and Omar Tliba

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Airway smooth muscle as an immunomodulatory cell., Gautam Damera; Omar Tliba; and Reynold A. Panettieri, Jr.

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Subconjunctivally implantable hydrogels with degradable and thermoresponsive properties for sustained release of insulin to the retina., Gauri P. Misra, Ravi S.J. Singh, Tomas S. Aleman, Samuel G. Jacobson, Thomas W. Gardner, and Tao L. Lowe

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Title: Student Readiness For Interprofessional Learning: Baseline and Midpoint in the Jefferson Health Mentor Program, Elena M. Umland, Cynthia A. Sanoski, Jon Veloski, Kevin Lyons, Carolyn Giordano, Christine Arenson, and Molly Rose

Manuscripts from 2008

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Maternal cocaine administration in mice alters DNA methylation and gene expression in hippocampal neurons of neonatal and prepubertal offspring, Svetlana I. Novikova, Fang He, Jie Bai, Nicholas J. Cutrufello, Michael S. Lidow, and Ashiwel S. Undieh

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Diverse antidepressants increase CDP-diacylglycerol production and phosphatidylinositide resynthesis in depression-relevant regions of the rat brain, Kimberly R. Tyeryar, Habiba O.U. Vongtau, and Ashiwel S. Undieh