Seeing Is Believing: Optical Computed Tomography (OCT) and Histologic Analysis To Define Pathophysiology Of “Very”, Very Late Stent Thrombosis Occurring More Than 7 Years After Drug Eluting Stent Implantation

Authors

Antony G. Kaliyadan, MD, Thomas Jefferson UniversityFollow
Alec Vishnevsky, MD, Thomas Jefferson UniversityFollow
Henry Siu, MD, Thomas Jefferson University HospitalFollow
David Fishman, MD, Thomas Jefferson UniversityFollow
John Farber, MD, Center for Translational Medicine, Cardiology Division, Thomas Jefferson UniversityFollow
Nicholas Ruggiero II, MD, Thomas Jefferson UniversityFollow
Michael P. Savage, MD, Jefferson Medical CollegeFollow

Document Type

Poster

Publication Date

9-13-2014

Comments

Presented at: Transcather therapeutics (TCT 2014) in Washington DC.

Abstract

Case Presentation

• 58-year-old male with prior non-ST elevation MI with PCI performed using a sirolimus eluting stent placed in a large OM1 branch 86 months prior presented with five hours chest pain similar to prior MI >7 years earlier.
• Additional history of hypertension, hyperlipidemia, non-compliance with antiplatelet therapy and active tobacco abuse at time of presentation.
• Patient reported self-discontinuation of medications (aspirin (time unknown), statin, beta blocker) and resumed smoking.
• Clopidogrel was discontinued by his primary physician 97 days prior to presentation
• Initial electrocardiogram revealed a lateral ST elevation MI and the patient was taken to the cardiac catheterization lab for urgent coronary angiography.

Recommended Citation

Kaliyadan, MD, Antony G.; Vishnevsky, MD, Alec; Siu, MD, Henry; Fishman, MD, David; Farber, MD, John; Ruggiero II, MD, Nicholas; and Savage, MD, Michael P., "Seeing Is Believing: Optical Computed Tomography (OCT) and Histologic Analysis To Define Pathophysiology Of “Very”, Very Late Stent Thrombosis Occurring More Than 7 Years After Drug Eluting Stent Implantation" (2014). Department of Pathology, Anatomy, and Cell Biology Faculty Papers. Paper 151.
https://jdc.jefferson.edu/pacbfp/151