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Manuscripts from 2025

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Twelve Tips to Help Junior Faculty Review Medical Education Literature with Confidence, Abagayle Bierowski, Casey Morrone, Ridhima Ghei, Michael Pasirstein, and Dimitrios Papanagnou

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Evaluating the Role of Traditional and Nontraditional Educational Resources in Point-Of-Care Ultrasound Training: A Cross-Sectional Survey of Educator Preferences and Practices, Arthur Broadstock, Annahieta Kalantari, Almaz S. Dessie, Al'ai Alvarez, Resa E. Lewiss, Josie Acuna, Anthony Weekes, Kaylah Maloney, Uwe Stolz, Lori Stolz, and Aalap Shah

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Impact of Sars-Cov-2 on Healthcare and Essential Workers: A Longitudinal Study of Promis-29 Outcomes, Jocelyn Dorney, Imtiaz Ebna Mannan, Caitlin Malicki, Lauren E. Wisk, Joann Elmore, Kelli N. O'Laughlin, Dana Morse, Kristyn Gatling, Michael Gottlieb, Michelle Santangelo, Michelle L'Hommedieu, Nicole L. Gentile, Sharon Saydah, Mandy J. Hill, Ryan Huebinger, Katherine Riley Martin, Ahamed H. Idris, Efrat Kean, Kevin Schaeffer, Robert M. Rodriguez, Robert A. Weinstein, Erica S. Spatz, and INSPIRE Group

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Machine Learning to Optimize Use of Natriuretic Peptides in the Diagnosis of Acute Heart Failure, Dimitrios Doudesis, Kuan Ken Lee, Mohamed Anwar, Adam J. Singer, Judd E. Hollander, Camille Chenevier-Gobeaux, Yann-Erick Claessens, Desiree Wussler, Dominic Weil, Nikola Kozhuharov, Ivo Strebel, Zaid Sabti, Christopher deFilippi, Stephen Seliger, Evandro Tinoco Mesquita, Jan C. Wiemer, Martin Möckel, Joel Coste, Patrick Jourdain, Komukai Kimiaki, Michihiro Yoshimura, Irwani Ibrahim, Shirley Beng Suat Ooi, Win Sen Kuan, Alfons Gegenhuber, Thomas Mueller, Olivier Hanon, Jean-Sébastien Vidal, Peter Cameron, Louisa Lam, Ben Freedman, Tommy Chung, Sean P. Collins, Christopher J. Lindsell, David E. Newby, Alan G. Japp, Anoop S. V. Shah, Humberto Villacorta, A. Mark Richards, John J V McMurray, Christian Mueller, James L. Januzzi, Nicholas L. Mills, Gordon Moe, Carlos Fernando, Hanna K. Gaggin, Antoni Bayes-Genis, Roland RJ Van Kimmenade, Yigal Pinto, Joost H. W. Rutten, Anton H. Van Den Meiracker, Luna Gargani, Nicola R. Pugliese, Pemberton Christopher, Michael Neumaier, Michael Behnes, Ibrahim Akin, Michele Bombelli, Guido Grassi, Peiman Nazerian, Giovanni Albano, and Philipp Bahrmann

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Machine Learning to Optimize Use of Natriuretic Peptides in the Diagnosis of Acute Heart Failure, Dimitrios Doudesis; Kuan Ken Lee; Mohamed Anwar; Adam J. Singer; Judd Hollander, MD; Camille Chenevier-Gobeaux; Yann-Erick Claessens; Desiree Wussler; Dominic Weil; Nikola Kozhuharov; Ivo Strebel; Zaid Sabti; Christopher deFilippi; Stephen Seliger; Evandro Tinoco Mesquita; Jan C. Wiemer; Martin Möckel; Joel Coste; Patrick Jourdain; Komukai Kimiaki; Michihiro Yoshimura; Irwani Ibrahim; Shirley Beng Suat Ooi; Win Sen Kuan; Alfons Gegenhuber; Thomas Mueller; Olivier Hanon; Jean-Sébastien Vidal; Peter Cameron; Louisa Lam; Ben Freedman; Tommy Chung; Sean P. Collins; Christopher J Lindsell; David E. Newby; Alan G. Japp; Anoop S V Shah; Humberto Villacorta; A Mark Richards; John J V McMurray; Christian Mueller; James L. Januzzi; and Nicholas L. Mills

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MBiochemical Identification and Clinical Description of edetomidine Exposure in People Who Use Fentanyl in Philadelphia, PA, Phil Durney, Jennifer L. Kahoud, TaReva Warrick-Stone, Maeve Montesi, Meg Carter, Sabrina Butt, Alberto Martinez Mencia, Louisa Omoregie, Monali Shah, Mariah Bloomfield, Nicholas Tomasko, Rebecca C. Jaffe, Allison Herens, Warren R. Korn, Karen Alexander, Douglas F. Stickle, Dennis Goodstein, Lara Weinstein, and Kory S. London

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Exploring the Impact of the Emergency Department Built Environment on Physician Workplace Stress: A Qualitative Study Utilizing High-Fidelity Virtual Reality, J Matthew Fields, Alan Price, Billie Faircloth, Eden Blas, Marah Sakkal, Sabrina Naumovski, Robert Ries, Callum Hamilton, Kit Elsworth, Morgan Hutchinson, Bon Ku, Christopher Connock, and Jennifer Kahoud

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Work Impairment and Financial Outcomes Among Adults With vs Without Long COVID, Michael Gottlieb, Ji Chen, Huihui Yu, Michelle Santangelo, Erica S. Spatz, Nicole L. Gentile, Rachel E. Geyer, Caitlin Malicki, Kristyn Gatling, Kelli N. O'Laughlin, Kari A. Stephens, Joann G. Elmore, Lauren E. Wisk, Michelle L'Hommedieu, Robert Rodriguez, Juan Carlos C. Montoy, Ralph C. Wang, Kristin L. Rising, Efrat Kean, Jonathan W. Dyal, Mandy J. Hill, Arjun K. Venkatesh, and Robert A. Weinstein

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Differences in Long COVID Severity by Duration of Illness, Symptom Evolution, and Vaccination: A Longitudinal Cohort Study from the INSPIRE Group, Michael Gottlieb, Huihui Yu, Ji Chen, Erica S. Spatz, Nicole L. Gentile, Rachel E. Geyer, Michelle Santangelo, Caitlin Malicki, Kristyn Gatling, Sharon Saydah, Kelli N. O'Laughlin, Kari A. Stephens, Joann G. Elmore, Lauren E. Wisk, Michelle L'Hommedieu, Robert M. Rodriguez, Juan Carlos C. Montoy, Ralph C. Wang, Kristin L. Rising, Efrat Kean, Jonathan W. Dyal, Mandy J. Hill, Arjun K. Venkatesh, and Robert A. Weinstein

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Acute Carpal Tunnel Syndrome Secondary to Handcuffs Necessitating Emergency Orthopedic Consultation and Operative Intervention, Fabian Jano, Kelly MacKenzie, Vivek Biololikar, David Goldberger, and Andrei Tuluca

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Assessing the Cardiac Safety of a Multimodal Protocol for 'Tranq Dope' Withdrawal: A Retrospective QTc Analysis, Kory London, Emily Deschler, Sabrina Butt, Steven Graver, Jake Figaniak, Nathan Hersh, Ariana Rucker, Bogdan Popa, Jenna Hoopes, Jennifer Kahoud, and Behzad Pavri

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“Are You Worried About Going Into Withdrawal Today?” Retrospective Analysis of Single-Question, Patient-Centered Screen for Substance Use and Care Linkage, Kory S. London, Beth Hurwitz, Jennifer Davis, TaReva Warrick-Stone, Alan Cherney, Frederick Randolph, Bernice Bradley-O'Toole, Kate Deis, and Karen Alexander

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Development and Validation of Risk Stratification for Heart Failure After Acute Coronary Syndrome Based on Dynamic S100A8/A9 Levels, Jie Ma, Ke Ma, Jing Chen, Xinying Yang, Fei Gao, Hai Gao, Hui Zhang, Xin-Liang Ma, Jie Du, Ping Li, and Yulin Li

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Participant Engagement in a National Longitudinal Study of COVID-19: Insights From the INSPIRE Study, Kris Pui Kwan Ma, Tracy Stober, Michael Gottlieb, Rachel E. Geyer, Kristin L. Rising, Sharon Saydah, Michelle Santangelo, Kristyn Gatling, Dylan Grau, Ralph C. Wang, Juan Carlos Montoy, Ahamed Idris, Samuel MacDonald, Mandy J. Hill, Ryan Huebinger, Maria G. Prado, Nicole L. Gentile, Erica Spatz, Caitlin Maliki, Jocelyn Dorney, Joann G. Elmore, Michelle L'Hommedieu, Robert A Weinstein, Arjun K. Venkatesh, and Kari A. Stephens

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Sustained Impact: Long-Term Application of Diagnostic Uncertainty Communication Training, Danielle M. McCarthy; Jethel Hernandez; Dimitrios Papanagnou; Kenzie A. Cameron; David H, Salzman; Andrew W. Long; Alexandra D. Franiek; and Kristin L. Rising

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Targeted EHR-Based Communication of Diagnostic Uncertainty (TECU) in the Emergency Department: Protocol for an Effectiveness Implementation Trial, Danielle M McCarthy, Sara Malone, Dimitrios Papanagnou, Benjamin E Leiby, Amandy M B Doty, Phillip Watts, Rahul Yadav, Julia K Pugliese, Jonathan Woodworth, Tracy Esteves Camacho, Efrat Kean, and Kristin L Rising

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Assessment of Emergency Medicine Residents' Situational Awareness and Perception of Patient Safety Culture in the Emergency Department, Adriana Olson, Nathan Olson, Nicholas Hartman, Casey Morrone, Morgan Battaglia, and Kamna Balhara

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The Effect of SARS-CoV-2 Reinfection on Long-Term Symptoms in the Innovative Support for Patients with SARS-CoV-2 Infections Registry (INSPIRE), John J. Openshaw, Ji Chen, Robert Rodriguez, Michael Gottlieb, Kalyani McCullough, Michelle Santangelo, Mandy J. Hill, Kristyn Gatling, Ahamed H. Idris, Samuel McDonald, Lauren E. Wisk, Jonathan Dyal, Ralph C. Wang, Kristin L. Rising, Efrat Kean, Kelli N. O'Laughlin, Kari A. Stephens, Caitlin Malicki, Zhenqiu Lin, Erica S. Spatz, Huihui Yu, Robert A. Weinstein, and Joann Elmore

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Factors Associated With Corrective Actions, Remediation, and Employment Termination of Emergency Physicians, Lyndsay Tyler, Yachana Bhakta, Michael Gottlieb, Chadd K. Kraus, Terry Kowalenko, Yvette Calderon, Samuel M. Keim, Diane L. Gorgas, Deborah B. Diercks, and Lewis S. Nelson

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Association of SARS-CoV-2 With Health-related Quality of Life 1 Year After Illness Using Latent Transition Analysis, Lauren Wisk, Michael Gottlieb, Peizheng Chen, Huihui Yu, Kelli O'Laughlin, Kari Stephens, Graham Nichol, Juan Carlos Montoy, Robert Rodriguez, Michelle Santangelo, Kristyn Gatling, Erica Spatz, Arjun Venkatesh, Kristin Rising, Mandy Hill, Ryan Huebinger, Ahamed Idris, Michael Willis, Efrat Kean, Samuel McDonald, Joann Elmore, and Robert Weinstein

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Does Cognitive Frame Affect Clinical Reasoning Among Medical Students? A Cross-Sectional Study, Xiao C. Zhang, Sara A. Belko, and Andrew J Monick

Manuscripts from 2024

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Exploring Medical Student Experiences of Trauma in the Emergency Department: Opportunities for Trauma-informed Medical Education, Giselle Appel, Ahmed Shahzad, Kestrel Reopelle, Stephen DiDonato, Frances Rusnack, and Dimitrios Papanagnou

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Transcription and Post-translational Mechanisms: Dual Regulation of Adiponectin-Mediated Occludin Expression in Diabetes, Yanru Duan, Demin Liu, Huahui Yu, Shihan Zhang, Yihua Xia, Zhiyong Du, Yanwen Qin, Yajing Wang, Xin-Liang Ma, Huirong Liu, and Yunhui Du

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Analysis of Anonymous Student Narratives About Experiences with Emergency Medicine Residency Programs, Molly Estes, Jacob Garcia, Ronnie Ren, Mark Olaf, Shannon Moffett, Michael Galuska, and Xiao C. Zhang

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Elderly Female With Abdominal Pain and Hypotension, Michael Fareri, Arthur K Au, Kelly Goodsell, and M. Fields

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Scurvy: A Rare Disease or a Rare Diagnosis?, David F. Gaieski

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Adipocyte-Derived Small Extracellular Vesicles Exacerbate Diabetic Ischemic Heart Injury by Promoting Oxidative Stress and Mitochondrial-Mediated Cardiomyocyte Apoptosis, Lu Gan, Jianli Zhao, Peng Yao, Theodore A. Christopher, Bernard Lopez, Wayne B. Lau, Walter Koch, Erhe Gao, Xin-Liang Ma, and Yajing Wang

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Emergency Department Slit Lamp Interdisciplinary Training Via Longitudinal Assessment in Medical Practice, Samara Hamou, Shayan Ghiaee, Christine Chung, Maureen Lloyd, Kelly Khem, and Xiao Zhang

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Digital Health Research Symposium: Closing Panel Commentary, Judd E. Hollander, Kristin L. Rising, and Brian M. Dougan

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Hereditary Spherocytosis Due to a Novel Variant, p.Q1034X, in the beta subunit of the spectrin gene: A Case Report, Emmalee M. Kugler, Akash Patel, Faraz Afridi, Maria I. Scarano, and Rafat Ahmed

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Cardiomyocyte-Derived Small Extracellular Vesicle: a New Mechanism Driving Diabetic Cardiac Fibrosis and Cardiomyopathy, Yu Li, Yunhui Du, Yang Liu, Xiuhuan Chen, Xinxin Li, Yanru Duan, Yanwen Qin, Huirong Liu, Xinliang Ma, Shaoping Nie, and Huina Zhang

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Tranq Dope: Characterization of an ED Cohort Treated With a Novel Opioid Withdrawal Protocol in the Era of Fentanyl/Xylazine, Kory London, Yutong Li, Jennifer Kahoud, Davis Cho, Jamus Mulholland, Sebastian Roque, Logan Stugart, Jeffrey Gillingham, Elias Borne, and Benjamin Slovis

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S100A8/A9 as a Prognostic Biomarker with Causal Effects for Post-Acute Myocardial Infarction Heart Failure, Jie Ma, Yang Li, Ping Li, Xinying Yang, Shuolin Zhu, Ke Ma, Fei Gao, Hai Gao, Hui Zhang, Xin-Liang Ma, Jie Du, and Yulin Li

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"Addressing Barriers to Digital Health Readiness Among a Latino Population", Karla Martin Gonzalez, Alexzandra T. Gentsch, Chelsea Torres, Elias Borne, Josefina Hendry, Lianette Pappaterra, Maryann Salib, Brooke Worster, Steven Gravier-Leon, and Kristin L. Rising

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Recommendations From People Who Use Drugs in Philadelphia, PA About Structuring Point-Of-Care Drug Checking, Megan K. Reed, Elias Borne, Tracy Esteves Camacho, Morgan Kelly, and Kristin L. Rising

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Long COVID Among Undocumented Latino Immigrant Populations in the Emergency Department., Karen P. Reyes, Zubaid Rafique, Brian Chinnock, Vijaya Arun Kumar, Michael Gottlieb, Kristin L. Rising, and Robert M. Rodriguez

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Relationship Between On-Demand Telehealth Visits and Emergency Department and Hospital Surge During the COVID-19 Pandemic, B. H. Slovis, Xin Ji, Anna Marie Chang, John C. Kairys, and Judd Hollander

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Increased Usage of Doxycycline for Young Children With Lyme Disease, Amy Thompson, Desiree Neville, Laura Chapman, Fran Balamuth, Meagan Ladell, Anupam Kharbanda, Rachael Aresco, and Lise Nigrovic

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Myalgic Encephalomyelitis/Chronic Fatigue Syndrome After SARS-CoV-2 Infection, Elizabeth R. Unger, Jin-Mann S. Lin, Lauren E. Wisk, Huihui Yu, Michelle L'Hommedieu, Helen Lavretsky, Juan Carlos C. Montoy, Michael A. Gottlieb, Kristin L. Rising, Nicole L. Gentile, Michelle Santangelo, Arjun K. Venkatesh, Robert M. Rodriguez, Mandy J. Hill, Rachel E. Geyer, Efrat R. Kean, Sharon Saydah, Samuel A. McDonald, Ryan Huebinger, Ahamed H. Idris, Jocelyn Dorney, Bala Hota, Erica S. Spatz, Kari A. Stephens, Robert A. Weinstein, and Joann G. Elmore

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The Association Between Prolonged SARS-CoV-2 Symptoms and Work Outcomes, Arjun K Venkatesh, Huihui Yu, Caitlin Malicki, Michael Gottlieb, Joann G Elmore, Mandy J Hill, Ahamed H Idris, Juan Carlos C Montoy, Kelli N O'Laughlin, Kristin L. Rising, Kari A Stephens, Erica S Spatz, and Robert A Weinstein

Manuscripts from 2023

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Use of Serial Smartphone-Based Assessments to Characterize Diverse Neuropsychiatric Symptom Trajectories in a Large Trauma Survivor Cohort, Francesca L Beaudoin, Xinming An, Archana Basu, Yinyao Ji, Mochuan Liu, Ronald C Kessler, Robert F Doughtery, Donglin Zeng, Kenneth A Bollen, Stacey L House, Jennifer S Stevens, Thomas C Neylan, Gari D Clifford, Tanja Jovanovic, Sarah D Linnstaedt, Laura T Germine, Scott L Rauch, John P Haran, Alan B Storrow, Christopher Lewandowski, Paul I Musey, Phyllis L Hendry, Sophia Sheikh, Christopher W Jones, Brittany E Punches, Michael C Kurz, Robert A Swor, Vishnu P Murty, Meghan E McGrath, Lauren A Hudak, Jose L Pascual, Elizabeth M Datner, Anna Marie Chang, Claire Pearson, David A Peak, Roland C Merchant, Robert M Domeier, Niels K Rathlev, Brian J O' Neil, Paulina Sergot, Leon D Sanchez, Steven E Bruce, Justin T Baker, Jutta Joormann, Mark W Miller, Robert H Pietrzak, Deanna M Barch, Diego A Pizzagalli, John F Sheridan, Jordan W Smoller, Steven E Harte, James M Elliott, Karestan C Koenen, Kerry J Ressler, and Samuel A McLean

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Changing The Playbook For Immigrant Health, Cheryl Bettigole, Patricia C. Henwood, Sage Myers, and Maura Sammon

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Delay in Hospital Presentation is the Main Reason Large Vessel Occlusion Stroke Patients Do Not Receive Intravenous Thrombolysis, Ethan Brandler, Derek Isenberg, Joseph Herres, Huaqing Zhao, Chadd Kraus, Daniel Ackerman, Adam Sigal, Alexander Kuc, Jason Nomura, Susan Wojcik, Michael Mullen, and Nina Gentile

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#StopTheStigmaEM: Building a Social Media-Based Movement to Support Emergency Medicine Mental Health, Amanda J. Deutsch, Al'ai Alvarez, Stephanie Balint, Ryan D. Pappal, Stacey Roseen, Wendy W. Sun, Jonathan Warren, Kelsey Stanton, and Anish K. Agarwal

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Adiponectin-Mediated Promotion of CD44 Suppresses Diabetic Vascular Inflammatory Effects, Yanru Duan, Shihan Zhang, Yuanyuan Xing, Ye Wu, Wen Zhao, Pinxue Xie, Huina Zhang, Xinxiao Gao, Yanwen Qin, Yajing Wang, Xin-Liang Ma, Yunhui Du, and Huirong Liu

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What Regenerative Agriculture Can Teach Medical Students About Human Health, David Ebbott and Dimitrios Papanagnou

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Are Patients With an International Classification of Diseases, 10th Edition Discharge Diagnosis Code for Sepsis Different in Regard to Demographics and Outcome Variables When Comparing Those With Sepsis Only to Those Also Diagnosed With COVID-19 or Those With a COVID-19 Diagnosis Alone?, David F. Gaieski, Jumpei Tsukuda, Parker Maddox, and Michael Li

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Long COVID Clinical Phenotypes up to 6 Months After Infection Identified by Latent Class Analysis of Self-Reported Symptoms, Michael Gottlieb, Erica S. Spatz, Huihui Yu, Lauren E Wisk, Joann G. Elmore, Nicole L. Gentile, Mandy Hill, Ryan M. Huebinger, Ahamed H. Idris, Efrat M. Kean, Katherine Koo, Shu-Xia Li, Samuel McDonald, Juan Carlos C Montoy, Graham Nichol, Kelli N. O'Laughlin, Ian D. Plumb, Kristin L. Rising, Michelle Santangelo, Sharon Saydah, Ralph C. Wang, Arjun Venkatesh, Kari A. Stephens, and Robert A. Weinstein

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A Chinese Scoring System for Predicting Successful Retrograde Collateral Traverse In Patients With Chronic Total Coronary Occlusion, Qiu Yu Li, Xiao Long Lin, Fan Qi Li, Zi Chao Cheng, Jia Yu Tian, Dong Hui Zhao, Wayne Bond Lau, Jing Hua Liu, and Qian Fan

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Presence of Symptoms 6 Weeks After COVID-19 Among Vaccinated and Unvaccinated US Healthcare Personnel: A Prospective Cohort Study, Nicholas M. Mohr, Ian D. Plumb, Kari K. Harland, Tamara Pilishvili, Katherine E. Fleming-Dutra, Anusha Krishnadasan, Karin F. Hoth, Sharon H. Saydah, Zachary Mankoff, John P. Haran, Melissa Briggs-Hagen, Eliezer Santos León, and David A. Talan

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Emergency Department Presentations of Diabetic Ketoacidosis in a Large Cohort of Children, Lisa E. Nigrovic, Nathan Kuppermann, Simona Ghetti, Jeff E. Schunk, Michael J. Stoner, Arleta Rewers, Julie K. McManemy, Kimberly S. Quayle, Jennifer L. Trainor, Leah Tzimenatos, Jonathan E. Bennett, Maria Y. Kwok, Sage R. Myers, Kathleen M. Brown, T. Charles Casper, Cody S. Olsen, and Nicole S. Glaser

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Intolerance of Uncertainty and Attitudes Towards Persons Living with Disabilities in Medical Students: Is There a Correlation?, Martinique Ogle; Dimitrios Papanagnou, MD; Kestrel Reopelle; Frances Rusnack; Jordan Feingold-Link; Maria Poluch; and Nethra S. Ankam

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Effectiveness of a Messenger RNA Vaccine Booster Dose Against Coronavirus Disease 2019 Among US Healthcare Personnel, October 2021-July 2022, Ian D. Plumb, Nicholas M. Mohr, Melissa Hagen, Ryan Wiegand, Ghinwa Dumyati, Karisa K. Harland, Anusha Krishnadasan, Jade James Gist, Glen Abedi, Katherine E Fleming-Dutra, Nora Chea, Jane Lee, Devra Barter, Monica Brackney, Scott K. Fridkin, Lucy E. Wilson, Sara A. Lovett, Valerie Ocampo, Erin C. Phipps, Tiffanie M. Marcus, Howard A. Smithline, Peter C. Hou, Lilly C. Lee, Gregory J. Moran, Elizabeth Krebs, Mark T. Steele, Stephen C. Lim, Walter A. Schrading, Brian Chinnock, David G. Beiser, Brett Faine, John P. Haran, Utsav Nandi, Anne K. Chipman, Frank LoVecchio, David A. Talan, and Tamara Pilishvili

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Sorting Through Life: Evaluating Patient-Important Measures of Success in a Medication for Opioid Use Disorder (MOUD) Treatment Program, Megan K Reed, Kelsey R Smith, Francesca Ciocco, Richard W. Hass, Avery Lin Cox, Erin L Kelly, and Lara Weinstein

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A Prioritized Patient-Centered Research Agenda to Reduce Disparities in Telehealth Uptake: Results from a National Consensus Conference, Kristin L. Rising, Mackenzie Kemp, Amy E. Leader, Anna Marie Chang, Andrew J. Monick, Amanda Guth, Tracy Esteves Camacho, Gregory Laynor, and Brooke Worster

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A Case of Malignant Atrophic Papulosis with Septic Complications, Mengjiao Tao, Kaiwen Zhuang, Yaowen Jiang, Wayne Bond Lau, and Yarong He

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Telehealth Clinical Appropriateness and Quality, Lulu Wang, Anthony Fabiano, Arjun K. Venkatesh, Nick Patel, and Judd E. Hollander

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Association Between SARS-CoV-2 Variants and Frequency of Acute Symptoms: Analysis of a Multi-institutional Prospective Cohort Study-December 20, 2020-June 20, 2022., Ralph C, Wang; Michael Gottlieb; Juan Carlos C. Montoy; Robert M. Rodriguez; Huihui Yu; Erica S. Spatz; Christopher W. Chandler; Joann G. Elmore; Paavali A. Hannikainen; Anna Marie Chang; Mandy Hill; Ryan M. Huebinger; Ahamed H. Idris; Katherine Koo; Shu-Xia Li; Samuel McDonald; Graham Nichol; Kelli N. O'Laughlin; Ian D. Plumb; Michelle Santangelo; Sharon Saydah; Kari A. Stephens; Arjun K. Venkatesh; and Robert A. Weinstein

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Rationale and Design of the RESTORE Trial: A Multicenter, Randomized, Double-Blinded, Parallel-Group, Placebo-Controlled Trial to Evaluate the Effect of Shenfu Injection on Myocardial Injury in STEMI Patients After Primary PCI, Xiao Wang, Ruifeng Guo, Yingying Guo, Qian Guo, Yan Yan, Wei Gong, Wen Zheng, Hui Wang, Lei Xu, Hui Ai, Bin Que, Xiaoyan Yan, Xin-Liang Ma, and Shaoping Nie

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Neighborhood Disadvantage and Neural Correlates of Threat and Reward Processing in Survivors of Recent Trauma, E. Kate Webb, Timothy D. Ely, Grace E. Rowland, Lauren A.M. Lebois, Sanne J.H. van Rooij, Steven E. Bruce, Tanja Jovanovic, Stacey L. House, Francesca L. Beaudoin, Xinming An, Thomas C. Neylan, Gari D. Clifford, Sarah D. Linnstaedt, Laura T. Germine, Kenneth A. Bollen, Scott L. Rauch, John P. Haran, Alan B. Storrow, Christopher Lewandowski, Paul I. Musey, Phyllis L. Hendry, Sophia Sheikh, Christopher W. Jones, Brittany E. Punches, Robert A. Swor, Jose L. Pascual, Mark J. Seamon, Elizabeth M. Datner, Claire Pearson, David A. Peak, Roland C. Merchant, Robert M. Domeier, Niels K. Rathlev, Paulina Sergot, Leon D. Sanchez, Ronald C. Kessler, Karestan C. Koenen, Samuel A. McLean, Jennifer S. Stevens, Kerry J. Ressler, and Nathaniel G. Harnett

Manuscripts from 2022

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Advanced Triage Protocol: The Role of an Automated Lactate Order in Expediting Rapid Identification of Patients at Risk of Sepsis in the Emergency Department, Andrew Baum, Brendan G Carr, Sarah M Perman, Jennifer Barger, Munish Goyal, and David F. Gaieski

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Emergency Department Communication in Persons Living With Dementia and Care Partners: A Scoping Review, Christopher R Carpenter, Jesseca Leggett, Fernanda Bellolio, Marian Betz, Ryan M Carnahan, David Carr, Michelle Doering, Jennie Chin Hansen, Eric D Isaacs, Deborah Jobe, Kathleen Kelly, Nancy Morrow-Howell, Beth Prusaczyk, Bob Savage, Joe Suyama, Allan S Vann, Kristin L Rising, Ula Hwang, and Manish N Shah

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Troponin Is Unrelated to Outcomes in Heart Failure Patients Discharged From the Emergency Department, Gregory J Fermann, Jon W Schrock, Phillip D Levy, Peter Pang, Javed Butler, Anna Marie Chang, Douglas Char, Deborah Diercks, Jin H Han, Brian Hiestand, Chris Hogan, Cathy A Jenkins, Christy Kampe, Yosef Khan, Vijaya A Kumar, Sangil Lee, JoAnn Lindenfeld, Dandan Liu, Karen F Miller, W Frank Peacock, Carolyn M Reilly, Chad Robichaux, Russell L Rothman, Wesley H Self, Adam J Singer, Sarah A Sterling, Alan B Storrow, William B Stubblefield, Cheryl Walsh, John Wilburn, and Sean P Collins

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Curriculum Development by Design Thinking: Analyzing a Program for Social Determinants of Health Screening by Pre-Clerkship Medical Students., Ari M Fish, J Matthew Fields, Deborah Ziring, Gina McCoy, Paula Ostroff, and Geoffrey Hayden

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A Consensus List of Ultrasound Competencies for Graduating Emergency Medicine Residents, David A Haidar, William J Peterson, Patrick G Minges, Jennifer Carnell, Jason T Nomura, John Bailitz, Jeremy S Boyd, Megan M Leo, E Liang Liu, Youyou Duanmu, Josie Acuña, Ross Kessler, Marco F Elegante, Mathew Nelson, Rachel B Liu, Resa E. Lewiss, Arun Nagdev, and Rob D Huang

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The Art of Sim-Making: What to Learn from Film-Making, Fatimah Lateef, Brad Peckler, Eric Saindon, Shruti Chandra, Indrani Sardesai, Mohamed Alwi Abdul Rahman, S Vimal Krishnan, Afrah Abdul Wahid Ali, Rose V Goncalves, and Sagar Galwankar

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Using a Human-Centered, Mixed Methods Approach to Understand the Patient Waiting Experience and its Impact on Medically Underserved Populations, Elizabeth N. Liao, Lara Z. Chehab, Kathryn Neville, Jennifer Liao, Devika Patel, and Amanda Sammann

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Principles of Hypotensive Shock: A Video Introduction to Pathophysiology and Treatment Strategies, Brittany MacDonald, Nicholas MacDonald, Jacob Garcia, Xiao Chi Zhang, and Dimitrios Papanagnou

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A Just-in-Time Video Primer on Pneumothorax Pathophysiology and Early Management, Nicholas MacDonald, Jacob Garcia, Gregory C. Kane, Xiao Chi Zhang, and Dimitrios Papanagnou

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Emergency Medicine Clinician Experiences Addressing Uncertainty in First-Trimester Bleeding., Garrison Nord, Amanda Doty, Andrew J Monick, Danielle M McCarthy, Robin J Casten, Amer Z Aldeen, Philip S Nawrocki, and Kristin L. Rising

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Analyzing the Effect of Interview Time and Day on Emergency Medicine Residency Interview Scores, Alanna O’Connel, Sean Greco, Peter Tomaselli, Megan Stobart Gallagher, Robin Naples, and Dimitrios Papanagnou

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Study protocol for the Innovative Support for Patients with SARS-COV-2 Infections Registry (INSPIRE): A longitudinal study of the medium and long-term sequelae of SARS-CoV-2 infection, Kelli N O'Laughlin, Matthew Thompson, Bala Hota, Michael Gottlieb, Ian D Plumb, Anna Marie Chang, Lauren E Wisk, Aron J Hall, Ralph C Wang, Erica S Spatz, Kari A Stephens, Ryan M Huebinger, Samuel A McDonald, Arjun Venkatesh, Nikki Gentile, B. H. Slovis, Mandy Hill, Sharon Saydah, Ahamed H Idris, Robert Rodriguez, Harlan M Krumholz, Joann G Elmore, Robert A Weinstein, and Graham Nichol

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Informal and Incidental Learning in the Clinical Learning Environment: Learning Through Complexity and Uncertainty During COVID-19, Dimitrios Papanagnou, Karen E Watkins, Henriette Lundgren, Grace A Alcid, Deborah Ziring, and Victoria J Marsick

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Finding Acute Coronary Syndrome with Serial Troponin Testing for Rapid Assessment of Cardiac Ischemic Symptoms (FAST-TRAC): A Study Protocol, W Frank Peacock, Alan S Maisel, Christian Mueller, Stefan D Anker, Fred S Apple, Robert H Christenson, Paul Collinson, Lori B Daniels, Deborah B Diercks, Salvatore Di Somma, Gerasimos Filippatos, Gary Headden, Brian Hiestand, Judd Hollander, Juan C Kaski, Joshua M Kosowsky, John T Nagurney, Richard M Nowak, Donald Schreiber, Gary M Vilke, Marvin A Wayne, and Martin Than

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I Don't Have a Diagnosis for You: Preparing Medical Students to Communicate Diagnostic Uncertainty in the Emergency Department, Maria Poluch, Jordan Feingold-Link, Nethra S. Ankam, Jared Kilpatrick, Kenzie Cameron, Shruti Chandra, Amanda Doty, Matthew Klein, Danielle McCarthy, Kristin L. Rising, David Salzman, Deborah Ziring, and Dimitrios Papanagnou

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Predicting At-Risk Opioid Use Three Months After Ed Visit for Trauma: Results from the AURORA Study, Brittany E. Punches, Uwe Stolz, Caroline E. Freiermuth, Rachel M. Ancona, Samuel A. McLean, Stacey L. House, Francesca L. Beaudoin, Xinming An, Jennifer S. Stevens, Donglin Zeng, Thomas C. Neylan, Gari D. Clifford, Tanja Jovanovic, Sarah D. Linnstaedt, Laura T. Germine, Kenneth A. Bollen, Scott L. Rauch, John P. Haran, Alan B. Storrow, Christopher Lewandowski, Paul I. Musey Jr., Phyllis L. Hendry, Sophia Sheikh, Christopher W. Jones, Michael C. Kurz, Nina T. Gentile, Meghan E. McGrath, Lauren A. Hudak, Jose L. Pascual, Mark J. Seamon, Erica Harris, Anna M. Chang, Claire Pearson, David A. Peak, Roland C. Merchant, Robert M. Domeier, Niels K. Rathlev, Brian J. O'Neil, Leon D. Sanchez, Steven E. Bruce, Robert H. Pietrzak, Jutta Joormann, Deanna M. Barch, Diego A. Pizzagalli, Jordan W. Smoller, Beatriz Luna, Steven E. Harte, James M. Elliott, Ronald C. Kessler, Kerry J. Ressler, Karestan C. Koenen, and Michael S. Lyons

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"You can't go wrong being safe": Motivations, patterns, and context surrounding use of fentanyl test strips for heroin and other drugs., Megan K Reed, Amanda Guth, Venise J Salcedo, Jeffrey K Hom, and Kristin L Rising

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PROmotion of COvid-19 VA(X)ccination in the Emergency Department-PROCOVAXED: study protocol for a cluster randomized controlled trial., Robert M Rodriguez, Kelli O'Laughlin, Stephanie A Eucker, Anna Marie Chang, Kristin L. Rising, Graham Nichol, Alena Pauley, Hemal Kanzaria, Alexzandra Gentsch, Cindy Li, Herbie Duber, Jonathan Butler, Vidya Eswaran, and Dave Glidden

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Standardizing Evaluation of Patient-Specific 3D Printed Models in Surgical Planning: Development of a Cross-Disciplinary Survey Tool for Physician and Trainee Feedback, Lauren Schlegel, Michelle Ho, M. Fields, Erik Backlund, Robert S. Pugliese, and Kristy M. Shine

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COVID-19 Vaccine Equity: Codesigning Public Health Interventions With Community Partners, Eva Varotsis, Lauren Schlegel, B. H. Slovis, Patricia C. Henwood, Sandra E Brooks, Robert S. Pugliese, Bon Ku, and Morgan Hutchinson

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Association of Initial SARS-CoV-2 Test Positivity With Patient-Reported Well-being 3 Months After a Symptomatic Illness., Lauren E Wisk, Michael A Gottlieb, Erica S Spatz, Huihui Yu, Ralph C Wang, B. H. Slovis, Sharon Saydah, Ian D Plumb, Kelli N O'Laughlin, Juan Carlos C Montoy, Samuel A McDonald, Zhenqiu Lin, Jin-Mann S Lin, Katherine Koo, Ahamed H Idris, Ryan M Huebinger, Mandy J Hill, Nicole L Gentile, Anna Marie Chang, Jill Anderson, Bala Hota, Arjun K Venkatesh, Robert A Weinstein, Joann G Elmore, and Graham Nichol

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Extracellular Vesicle-Derived miR-144 as a Novel Mechanism for Chronic Intermittent Hypoxia-induced Endothelial Dysfunction, Huina Zhang, Lu Peng, Yifan Wang, Wen Zhao, Wayne Bond Lau, Yajing Wang, Yu Li, Yunhui Du, Linyi Li, Yu Huang, Shaoping Nie, Yanwen Qin, Xinliang Ma, and Yongxiang Wei

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Serum CTRP9 and high-molecular weight adiponectin are associated with ischemic stroke., Yan-Qing Zhang, Yan-Wei Zhang, Jian-Li Dai, Chen Li, Wen-Qing Wang, Hai-Feng Zhang, Wayne Bond Lau, Xiao-Ming Wang, Xiao-Gang Liu, and Rong Li

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Endothelial Autophagy in Coronary Microvascular Dysfunction and Cardiovascular Disease, Fujie Zhao, Ganesh Satyanarayana, Zheng Zhang, Jianli Zhao, Xin-Liang Ma, and Yajing Wang

Manuscripts from 2021

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Emergency Medicine and COVID-19: Now and Next Year, Theodore A. Christopher and Adrienne N. Christopher

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Early hemodynamic assessment using NICOM in patients at risk of developing Sepsis immediately after emergency department triage., Steve B Chukwulebe, David F. Gaieski, Abhishek Bhardwaj, Lakeisha Mulugeta-Gordon, Frances S Shofer, and Anthony J Dean

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Global point-of-care ultrasound education and training in the age of COVID-19., Onyinyechi F Eke, Patricia C. Henwood, Grace W Wanjiku, Abiola Fasina, Sigmund J Kharasch, and Hamid Shokoohi

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Nicotine aggravates vascular adiponectin resistance via ubiquitin-mediated adiponectin receptor degradation in diabetic Apolipoprotein E knockout mouse, Jia Gao, Jianghong Fan, Zhijun Meng, Rui Wang, Caihong Liu, Jing Liu, Bin Liang, Jing Wang, Yaoli Xie, Jing Zhao, Rui Guo, Jianli Zhao, Xin-Liang Ma, Xiangying Jiao, Jimin Cao, and Yajing Wang

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Atg16L1 as a Novel Biomarker and Autophagy Gene for Diabetic Retinopathy., Xinxiao Gao, Yunhui Du, Wayne Bond Lau, Yu Li, Siquan Zhu, and Xin-Liang Ma

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Analysis of an obstetrics point-of-care ultrasound training program for healthcare practitioners in Zanzibar, Tanzania., Elizabeth A Hall, Danielle Matilsky, Rachel Zang, Naomasa Hase, Ali Habibu Ali, Patricia C Henwood, and Anthony J Dean

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Building Trauma and EMS Systems Capacity in Rwanda: Lessons and Recommendations, Sudha Jayaraman, Faustin Ntirenganya, Menelas Nkeshimana, Ashley Rosenberg, Theophile Dushime, Ignace Kabagema, Jean Marie Uwitonze, Eric Uwitonize, Jeanne d'Arc Nyinawankusi, Robert Riviello, Irene Bagahirwa, Kenneth L Williams, Elizabeth Krebs, Rebecca Maine, Paulin Banguti, Stephen Rulisa, Patrick Kyamanywa, and Jean Claude Byiringiro

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Simulation Centers and Simulation-Based Education during the Time of COVID 19: A Multi-Center Best Practice Position Paper by the World Academic Council of Emergency Medicine., Fatimah Lateef, Madhavi Suppiah, Shruti Chandra, Too Xin Yi, Willy Darmawan, Brad Peckler, Veronica Tucci, Alfredo Tirado, Lorraine Mendez, Lisa Moreno, and Sagar Galwankar

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Identification of a CTRP9 C-Terminal polypeptide capable of enhancing bone-derived mesenchymal stem cell cardioprotection through promoting angiogenic exosome production., Demin Liu, Guoqiang Gu, Lu Gan, Wenjun Yan, Zhen Zhang, Peng Yao, Di Zhu, Wayne Bond Lau, Dina Xie, Sisi Wu, Zhijun Meng, Jumpei Tsukuda, Theodore Christopher, Bernard Lopez, Jianli Zhao, Erhe Gao, Walter Koch, Xin-Liang Ma, and Yajing Wang

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The Protective Effect of Traditional Chinese Medicine on Liver Ischemia-Reperfusion Injury., Wen Ma, Songling Tang, Dina Xie, Guoqiang Gu, and Lu Gan

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Coaching junior faculty for the uncertainties of academic professional practice, Richard McKnight and Dimitrios Papanagnou

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Pre-operative fluid resuscitation in the emergency general surgery septic patient: does it really matter?, Benjamin Moran, Erin Major, Joseph A Kufera, Samuel A Tisherman, and Jose Diaz

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Female with intermittently bleeding abdominal wall mass., Evan Osterman, Rebecca Lisowski, and Arthur Au

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Towards a medical school curriculum for uncertainty in clinical practice, Dimitrios Papanagnou, Nethra S. Ankam, David Ebbott, and Deborah Ziring

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Developing standardized patient-based cases for communication training: lessons learned from training residents to communicate diagnostic uncertainty., Dimitrios Papanagnou, Matthew R Klein, Xiao Chi Zhang, Kenzie A Cameron, Amanda Doty, Danielle M McCarthy, Kristin L. Rising, and David H Salzman

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The relationship between vitamin C or thiamine levels and outcomes for severe sepsis patients admitted to the ICU., Nandan Prasad, Anne V. Grossestreuer, Nuala J. Meyer, Sarah M. Perman, Mark E. Mikkelsen, Judd Hollander, and David F. Gaieski