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Manuscripts from 2018

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Pediatric Obesity: Influence on Drug Dosing and Therapeutics, Barbara Ameer PharmD, MBA, BCPS, FCP and Michael Weintraub MD

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CD38/cADPR Signaling Pathway in Airway Disease: Regulatory Mechanisms, Deepak A. Deshpande, PhD; Alonso G. P. Guedes; Richard Graeff; Soner Dogan; Subbaya Subramanian; Timothy F. Walseth; and Mathur S. Kannan

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Epigenetic Regulation of Tumor Suppressors by Helicobacter pylori Enhances EBV-Induced Proliferation of Gastric Epithelial Cells, Saurabh Pandey, Hem Chandra Jha, Sanket Kumar Shukla, Meghan K. Shirley, and Erle S. Robertson

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Repeated Measures of Blood and Breath Ammonia in Response to Control, Moderate and High Protein Dose in Healthy Men., Lisa A. Spacek, Arthur Strzepka, Saurabh Saha, Jonathan Kotula, Jeffrey Gelb, Sarah Guilmain, Terence Risby, and Steven F. Solga

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Synchronous gastric and duodenal metastases from head and neck squamous cell carcinoma: a unique presentation of upper gastrointestinal bleeding., Nicholas P. Tarangelo, Charles Andrew Kistler, Zachary Daitch, Wei Jiang, and Daniel M. Quirk

Manuscripts from 2017

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Of pools, oceans, and the Dead Sea., Samir K. Ballas

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Mobilized Peripheral Blood Stem Cells Versus Unstimulated Bone Marrow As a Graft Source for T-Cell-Replete Haploidentical Donor Transplantation Using Post-Transplant Cyclophosphamide., Asad Bashey; Mei-Jie Zhang; Shannon R McCurdy; Andrew St Martin; Trevor Argall; Claudio Anasetti; Stefan O Ciurea; Omotayo Fasan; Sameh Gaballa, MD; Mehdi Hamadani; Pashna Munshi; Monzr M Al Malki; Ryotaro Nakamura; Paul V O'Donnell; Miguel-Angel Perales; Kavita Raj; Rizwan Romee; Scott Rowley; Vanderson Rocha; Rachel B Salit; Melhem Solh; Robert J Soiffer; Ephraim Joseph Fuchs; and Mary Eapen

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Clinical Characteristics, Management, and Outcomes of Suspected Poststroke Acute Coronary Syndrome., Sylvia Marie Biso, Marvin Lu, Toni Anne De Venecia, Supakanya Wongrakpanich, Mary Rodriguez-Ziccardi, Sujani Yadlapati, Marina Kishlyansky, Harish Seetha Rammohan, and Vincent M. Figueredo

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A Review of Neurogenic Stunned Myocardium., Sylvia Biso, Supakanya Wongrakpanich, Akanksha Agrawal, Sujani Yadlapati, Marina Kishlyansky, and Vincent M. Figueredo

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Efficacy and Safety of Spironolactone in Acute Heart Failure: The ATHENA-HF Randomized Clinical Trial., Javed Butler, Kevin J. Anstrom, G. Michael Felker, Michael M. Givertz, Andreas P Kalogeropoulos, Marvin A. Konstam, Douglas L. Mann, Kenneth B. Margulies, Steven E McNulty, Robert J. Mentz, Margaret M. Redfield, W.H. Wilson Tang, David J. Whellan, Monica Shah, Patrice Desvigne-Nickens, Adrian F. Hernandez, and Eugene Braunwald

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Disseminated Nocardia cyriacigeorgia causing pancreatitis in a haploidentical stem cell transplant recipient., Jason Chen, MD; Jonathan Pan, MD; Joanne Filicko-O'Hara; Margaret Kasner; and Phyllis Flomenberg

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Treatment of Chronic Hepatitis B: An Update and Prospect for Cure, Andrew Dargan and Hie-Won Hann

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Effect of Oral Semaglutide Compared With Placebo and Subcutaneous Semaglutide on Glycemic Control in Patients With Type 2 Diabetes: A Randomized Clinical Trial., Melanie Davies, Thomas R. Pieber, Marie-Louise Hartoft-Nielsen, Oluf K.H. Hansen, Serge Jabbour, and Julio Rosenstock

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Oral Apolipoprotein A-I Mimetic D-4F Lowers HDL-Inflammatory Index in High-Risk Patients: A First-in-Human Multiple-Dose, Randomized Controlled Trial., Richard L. Dunbar, Rajesh Movva, LeAnne T. Bloedon, Danielle Duffy, Robert B. Norris, Mohamad Navab, Alan M. Fogelman, and Daniel J. Rader

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Effect of Natriuretic Peptide-Guided Therapy on Hospitalization or Cardiovascular Mortality in High-Risk Patients With Heart Failure and Reduced Ejection Fraction: A Randomized Clinical Trial., G. Michael Felker, Kevin J. Anstrom, Kirkwood F. Adams, Justin A Ezekowitz, Mona Fiuzat, Nancy Houston-Miller, James L. Januzzi, Daniel B. Mark, Ileana L. Piña, Gayle Passmore, David J. Whellan, Hongqiu Yang, Lawton S. Cooper, Eric S. Leifer, Patrice Desvigne-Nickens, and Christopher M O'Connor

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The Nephrotoxicity of Vancomycin., Edward J. Filippone, Walter K. Kraft, and John L. Farber

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Patient-reported outcome assessment of inflammatory arthritis patient experience with intravenously administered biologic therapy, Norman B. Gaylis, Joanne Sagliani, Shawn Black, Kezhen L. Tang, Raphael J. DeHoratius, Wesley A. Kafka, and Dennis Parenti

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Niche Cadherins Control the Quiescence-to-Activation Transition in Muscle Stem Cells., Aviva J. Goel, Marysia-Kolbe Rieder, Hans-Henning Arnold, Glenn L. Radice, and Robert S. Krauss

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The Value of Cancer Immunotherapy Summit at the 2016 Society for Immunotherapy of Cancer 31st anniversary annual meeting, Howard L. Kaufman; Michael B. Atkins; Adam Dicker MD, PhD; Heather S. Jim; Louis P. Garrison; Roy S. Herbst; William T. McGivney; Steven Silverstein; Jon M. Wigginton; and Peter P. Yu

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Effect of Oral Iron Repletion on Exercise Capacity in Patients With Heart Failure With Reduced Ejection Fraction and Iron Deficiency: The IRONOUT HF Randomized Clinical Trial., Gregory D Lewis, Rajeev Malhotra, Adrian F Hernandez, Steven E McNulty, Andrew Smith, G Michael Felker, W H Wilson Tang, Shane J LaRue, Margaret M Redfield, Marc J Semigran, Michael M Givertz, Peter Van Buren, David J Whellan, Kevin J Anstrom, Monica R Shah, Patrice Desvigne-Nickens, Javed Butler, and Eugene Braunwald

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Plekhg5-regulated autophagy of synaptic vesicles reveals a pathogenic mechanism in motoneuron disease., Patrick Lüningschrör, Beyenech Binotti, Benjamin Dombert, Peter Heimann, Angel Perez-Lara, Carsten Slotta, Nadine Thau-Habermann, Cora R. von Collenberg, Franziska Karl, Markus Damme, Arie Horowitz, Isabelle Maystadt, Annette Füchtbauer, Ernst-Martin Füchtbauer, Sibylle Jablonka, Robert Blum, Nurcan Üçeyler, Susanne Petri, Barbara Kaltschmidt, Reinhard Jahn, Christian Kaltschmidt, and Michael Sendtner

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An unknown reaction to pembrolizumab: giant cell arteritis., Ida Micaily, MD and Marc Chernoff, DO

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Evaluating the Relationship Between Participation in Student-Run Free Clinics and Changes in Empathy in Medical Students., Anita Modi, Michele Fascelli, Zachary Daitch, and Mohammadreza Hojat Professor

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Binding of CIB1 to the αIIb tail of αIIbβ3 is required for FAK recruitment and activation in platelets., Meghna U. Naik, Tejal U. Naik, Ross Summer, and Ulhas P. Naik

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Dabigatran Reversal with Idarucizumab., Charles V. Pollack, Paul A Reilly, and Jeffrey I Weitz

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Bitter Taste Receptor Agonists Mitigate Features of Allergic Asthma in Mice., Pawan Sharma, Roslyn Yi, Ajay P Nayak, Nadan Wang, Francesca Tang, Morgan J. Knight, Shi Pan, Brian Oliver, and Deepak A. Deshpande

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Intravesical rAd-IFNα/Syn3 for Patients With High-Grade, Bacillus Calmette-Guerin-Refractory or Relapsed Non-Muscle-Invasive Bladder Cancer: A Phase II Randomized Study., Neal D Shore, Stephen A Boorjian, Daniel J Canter, Kenneth Ogan, Lawrence I Karsh, Tracy M Downs, Leonard G Gomella, Ashish M Kamat, Yair Lotan, Robert S Svatek, Trinity J Bivalacqua, Robert L Grubb, Tracey L Krupski, Seth P Lerner, Michael E Woods, Brant A Inman, Matthew I Milowsky, Alan Boyd, F Peter Treasure, Gillian Gregory, David G Sawutz, Seppo Yla-Herttuala, Nigel R Parker, and Colin P N Dinney

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Influence of Sex/Gender and Race on Responses to Raltegravir Combined With Tenofovir-Emtricitabine in Treatment-Naive Human Immunodeficiency Virus-1 Infected Patients: Pooled Analyses of the STARTMRK and QDMRK Studies., Kathleen E. Squires, Linda-Gail Bekker, Christine Katlama, Yazdan Yazdanpanah, Yan Zhou, Anthony J Rodgers, Mark J DiNubile, Peter A Sklar, Randi Y Leavitt, and Hedy Teppler

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Discordance in investigator-reported and adjudicated sudden death in TIOSPIR., Robert A. Wise, Peter R. Kowey, George Austen, Achim Mueller, Norbert Metzdorf, Andy Fowler, and Lorcan P McGarvey

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CIB1 protects against MPTP-induced neurotoxicity through inhibiting ASK1., Kyoung Wan Yoon, Hyun-Suk Yang, Young Mok Kim, Yeonsil Kim, Seongman Kang, Woong Sun, Ulhas P. Naik, Leslie V. Parise, and Eui-Ju Choi

Manuscripts from 2016

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Heart Rhythm Monitoring Strategies for Cryptogenic Stroke: 2015 Diagnostics and Monitoring Stroke Focus Group Report., Gregory W. Albers, Richard A. Bernstein, Johannes Brachmann, John Camm, J. Donald Easton, Peter Fromm, Shinya Goto, Christopher B. Granger, Stefan H. Hohnloser, Elaine Hylek, Amir K. Jaffer, Derk W. Krieger, Rod Passman, Jesse M. Pines, Shelby D. Reed, Peter M. Rothwell, and Peter R. Kowey

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Utilization of HIV-1 envelope V3 to identify X4- and R5-specific Tat and LTR sequence signatures., Gregory C Antell, Will Dampier, Benjamas Aiamkitsumrit, Michael R Nonnemacher, Jeffrey M Jacobson, Vanessa Pirrone, Wen Zhong, Katherine Kercher, Shendra Passic, Jean W Williams, Gregory Schwartz, Uri Hershberg, Fred C Krebs, and Brian Wigdahl

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Lambda Red-mediated Recombineering in the Attaching and Effacing Pathogen Escherichia albertii., Marisa Egan, Jasmine Ramirez, Christian Xander, Chirag Upreti, and Shantanu Bhatt

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The Humoral Theory of Transplantation: Epitope Analysis and the Pathogenicity of HLA Antibodies., Edward J Filippone and John Farber

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Parental and staff perspectives of NICU research procedures., Christina Freibott, Ursula Guillen, Amy Mackley, and Robert Locke

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Childhood Psychosocial Determinants of Cardiovascular Health, Samuel S. Gidding and Erica D. Sood

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Evaluation of Polymorphic Locus Sequence Typing for Candida glabrata Epidemiology., Santosh Katiyar; Eric Shiffrin, MD; Celeste Shelton; Kelley Healey; John-Paul Vermitsky; and Tom Edlind

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Cell-free circulating mitochondrial DNA content and risk of hepatocellular carcinoma in patients with chronic HBV infection., Ling Li; Hie-Won Hann; Shaogui Wan; Richard Hann; Chun Wang; Yinzhi Lai; Xishan Ye; Alison Evans; Ronald E. Myers, PhD, DSW; Zhong Ye; Bingshan Li; Jinliang Xing; and Hushan Yang

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Cloning and Transcriptional Activity of the Mouse Omi/HtrA2 Gene Promoter., Dan Liu, Xin Liu, Ye Wu, Wen Wang, Xin-Liang Ma, and Huirong Liu

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Drugs for preventing red blood cell dehydration in people with sickle cell disease., Srikanth Nagalla and Samir K. Ballas

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Cannibalism, Kuru, and Mad Cows: Prion Disease As a "Choose-Your-Own-Experiment" Case Study to Simulate Scientific Inquiry in Large Lectures., Antonio Serrano, Jeffrey Liebner, and Justin K Hines

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A 22-year-old man with pleural tuberculosis associated hydropneumothorax: Case report and literature review., Lauren A Sharan; Thea Price, MD; Boyd Hehn; David Manoff, MD; and Scott W. Cowan, MD

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Hospitalized Patients at High Risk for Obstructive Sleep Apnea Have More Rapid Response System Events and Intervention Is Associated with Reduced Events., Sunil Sharma, MD; Anindita Chowdhury; Lili Tang; Leslee Willes; Brian Glynn; and Stuart F Quan

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Postoperative intussusception in 10-year-old presenting as decreased intestinal motility, Arielle Spellun, Loren Berman, and Stephen Murphy

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Conversion to eslicarbazepine acetate monotherapy: A pooled analysis of 2 phase III studies., Michael R Sperling, Jacqueline French, Mercedes P Jacobson, Ladislav Pazdera, Mallory Gough, Hailong Cheng, Todd Grinnell, and David Blum

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Reduction of CTRP9, a novel anti-platelet adipokine, contributes to abnormal platelet activity in diabetic animals., Wenqing Wang, Wayne Bond Lau, Yajing Wang, Xin-Liang Ma, and Rong Li

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Neural crest cell-autonomous roles of fibronectin in cardiovascular development., Xia Wang and Sophie Astrof

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Preparation and biological activity of the monoclonal antibody against the second extracellular loop of the angiotensin II type 1 receptor, Mingming Wei, Chengrui Zhao, Suli Zhang, Li Wang, Huirong Liu, and Xin-Liang Ma

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Stimulation of Transforming Growth Factor-β1-Induced Endothelial-To-Mesenchymal Transition and Tissue Fibrosis by Endothelin-1 (ET-1): A Novel Profibrotic Effect of ET-1., Peter J. Wermuth, Zhaodong Li, Fabian A. Mendoza, and Sergio A. Jimenez

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Monthly "Grief Rounds" to Improve Residents' Experience and Decrease Burnout in a Medical Intensive Care Unit Rotation., Lindsay Wilde, Brooke Worster, and David Oxman

Manuscripts from 2015

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J-wave syndromes: Brugada and early repolarization syndromes., Charles Antzelevitch and Gan-Xin Yan

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Chimeric cells of maternal origin do not appear to be pathogenic in the juvenile idiopathic inflammatory myopathies or muscular dystrophy., Carol M Artlett, Sihem Sassi-Gaha, Ronald C Ramos, Frederick W Miller, and Lisa G Rider

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Estimation of daily interfractional larynx residual setup error after isocentric alignment for head and neck radiotherapy: quality assurance implications for target volume and organs-at-risk margination using daily CT on- rails imaging., Charles A Baron, Musaddiq J Awan, Abdallah S R Mohamed, Imad Akel, David I Rosenthal, G Brandon Gunn, Adam S Garden, Brandon A Dyer, Laurence Court, Parag R Sevak, Esengul Kocak-Uzel, and Clifton D Fuller

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Human Polyclonal Antibodies Produced through DNA Vaccination of Transchromosomal Cattle Provide Mice with Post-Exposure Protection against Lethal Zaire and Sudan Ebolaviruses., Callie E Bounds, Steven A Kwilas, Ana I Kuehne, Jennifer M Brannan, Russell R Bakken, John M Dye, Jay W Hooper, Lesley C Dupuy, Barry Ellefsen, Drew Hannaman, Hua Wu, Jin-An Jiao, Eddie J Sullivan, Connie S Schmaljohn, and Matthias J. Schnell

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Fibronectin signals through integrin α5β1 to regulate cardiovascular development in a cell type-specific manner., Dongying Chen, Xia Wang, Dong Liang, Julie Gordon, Ashok Mittal, Nancy Manley, Karl Degenhardt, and Sophie Astrof

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Anxiety and depression in patients with advanced macular degeneration: current perspectives., Verena R Cimarolli, Robin J Casten, Barry W. Rovner, Vera Heyl, Silvia Sörensen, and Amy Horowitz

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Vertebral Body Stapling versus Bracing for Patients with High-Risk Moderate Idiopathic Scoliosis., Laury Cuddihy, Aina J Danielsson, Patrick J Cahill, Amer F Samdani, Harsh Grewal, John M Richmond, M J Mulcahey, John P Gaughan, M Darryl Antonacci, and Randal R Betz

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Inflammatory Muscle Diseases., Marinos Dalakas

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Dysregulation of the haem-haemopexin axis is associated with severe malaria in a case-control study of Ugandan children., Robyn E Elphinstone, Frank Riley, Tian Lin, Sarah Higgins, Aggrey Dhabangi, Charles Musoke, Christine Cserti-Gazdewich, Raymond F. Regan, H Shaw Warren, and Kevin C Kain

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The Effect of Aspirin on Bleeding and Transfusion in Contemporary Cardiac Surgery., Jordan E Goldhammer, Gregary D. Marhefka, Constantine Daskalakis, Mark W Berguson, John E Bowen, James Diehl, and Jianzhong Sun

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High Throughput Sequencing Identifies MicroRNAs Mediating α-Synuclein Toxicity by Targeting Neuroactive-Ligand Receptor Interaction Pathway in Early Stage of Drosophila Parkinson's Disease Model., Yan Kong, Xijun Liang, Lin Liu, Dongdong Zhang, Chao Wan, Zhenji Gan, Liudi Yuan, and Bing-Hua Jiang

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Practical management of anticoagulation in patients with atrial fibrillation., Richard J Kovacs, Greg C Flaker, Sherry J Saxonhouse, John U. Doherty, Kim K Birtcher, Adam Cuker, Bruce L Davidson, Robert P Giugliano, Christopher B Granger, Amir K Jaffer, Bella H Mehta, Edith Nutescu, and Kim A Williams

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DNA-Repair Defects and Olaparib in Metastatic Prostate Cancer., Joaquin Mateo, Suzanne Carreira, Shahneen Sandhu, Susana Miranda, Helen Mossop, Raquel Perez-Lopez, Daniel Nava Rodrigues, Dan Robinson, Aurelius Omlin, Nina Tunariu, Gunther Boysen, Nuria Porta, Penny Flohr, Alexa Gillman, Ines Figueiredo, Claire Paulding, George Seed, Suneil Jain, Christy Ralph, Andrew Protheroe, Syed Hussain, Robert Jones, Tony Elliott, Ursula McGovern, Diletta Bianchini, Jane Goodall, Zafeiris Zafeiriou, Chris T Williamson, Roberta Ferraldeschi, Ruth Riisnaes, Bernardette Ebbs, Gemma Fowler, Desamparados Roda, Wei Yuan, Yi-Mi Wu, Xuhong Cao, Rachel Brough, Helen Pemberton, Roger A'Hern, Amanda Swain, Lakshmi P Kunju, Rosalind Eeles, Gerhardt Attard, Christopher J Lord, Alan Ashworth, Mark A Rubin, Karen E Knudsen, Felix Y Feng, Arul M Chinnaiyan, Emma Hall, and Johann S de Bono

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Treatment-Induced Changes in Plasma Adiponectin Do Not Reduce Urinary Albumin Excretion in the Diabetes Prevention Program Cohort., Kieren J Mather, Qing Pan, William C Knowler, Tohru Funahashi, George A Bray, Richard Arakaki, Bonita Falkner, Kumar Sharma, and Barry J. Goldstein

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Expression of enteropathogenic Escherichia coli map is significantly different than that of other type III secreted effectors in vivo., Mai Nguyen, Jason Rizvi, and Gail Hecht

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Sex and race and/or ethnicity differences in patients undergoing radiofrequency ablation for Barrett's esophagus: results from the U.S. RFA Registry., Sarina Pasricha, Nan Li, William J. Bulsiewicz, Richard I. Rothstein, Anthony Infantolino, Atilla Ertan, Daniel S. Camara, Evan S. Dellon, George Triadafilopoulos, Charles J. Lightdale, Ryan D. Madanick, William D. Lyday, Raman V. Muthusamy, Bergein F. Overholt, and Nicholas J. Shaheen

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A Synthetic Lethality Screen Using a Focused siRNA Library to Identify Sensitizers to Dasatinib Therapy for the Treatment of Epithelial Ovarian Cancer., Harsh B Pathak, Yan Zhou, Geetika Sethi, Jeff Hirst, Russell J Schilder, Erica A Golemis, and Andrew K Godwin

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Tools for Economic Analysis of Patient Management Interventions in Heart Failure Cost-Effectiveness Model: A Web-based program designed to evaluate the cost-effectiveness of disease management programs in heart failure., Shelby D. Reed, Matthew P. Neilson, Matthew Gardner, Yanhong Li, Andrew H. Briggs, Daniel E E. Polsky, Felicia L. Graham, Margaret T. Bowers, Sara C. Paul, Bradi B. Granger, Kevin A. Schulman, David J. Whellan, Barbara Riegel, and Wayne C. Levy

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Immune Reconstitution but Persistent Activation After 48 Weeks of Antiretroviral Therapy in Youth With Pre-Therapy CD4 >350 in ATN 061., Bret J. Rudy, Bill G. Kapogiannis, Carol Worrell, Kathleen E. Squires, James Bethel, Su Li, Craig M. Wilson, Allison Agwu, Patricia Emmanuel, Georgine Price, Stephanie Hudey, Maureen M. Goodenow, and John W. Sleasman

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Effect of mycophenolate mofetil on the white blood cell count and the frequency of infection in systemic lupus erythematosus., Ananta Subedi, Laurence S. Magder, and Michelle Petri

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Emerging Novel Therapies for Heart Failure., Anthony M Szema, Sophia Dang, and Jonathan C Li

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Palbociclib in Hormone-Receptor-Positive Advanced Breast Cancer., Nicholas C Turner, Cynthia Huang Bartlett, and Massimo Cristofanilli

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Flattening filter-free accelerators: a report from the AAPM Therapy Emerging Technology Assessment Work Group., Ying Xiao, Stephen F Kry, Richard Popple, Ellen Yorke, Niko Papanikolaou, Sotirios Stathakis, Ping Xia, Saiful Huq, John Bayouth, James Galvin PhD, and Fang-Fang Yin

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Notching early repolarization pattern in inferior leads increases risk of ventricular tachyarrhythmias in patients with acute myocardial infarction: a meta-analysis., Zhiwei Zhang, Konstantinos P Letsas, Yajuan Yang, Panagiotis Korantzopoulos, Guangping Li, Gan-Xin Yan, and Tong Liu

Manuscripts from 2014

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Estimation of daily interfractional larynx residual setup error after isocentric alignment for head and neck radiotherapy: quality assurance implications for target volume and organs-at-risk margination using daily CT on- rails imaging., Charles A Baron, Musaddiq J Awan, Abdallah S R Mohamed, Imad Akel, David I Rosenthal, G Brandon Gunn, Adam S Garden, Brandon A Dyer, Laurence Court, Parag R Sevak, Esengul Kocak-Uzel, and Clifton D Fuller

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Peripheral arterial disease, prevalence and cumulative risk factor profile analysis., Luis H. Eraso Jefferson Vascular Center, Departments of Medicine and Surgery, Thomas Jefferson University; Eri Fukaya; Emile R Mohler; Dawei Xie; Daohang Sha; and Jeffrey S Berger

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Understanding the power of perinatal events and metabolic status in childhood., Bonita Falkner and Julie Ingelfinger

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Decreased levels of BAG3 in a family with a rare variant and in idiopathic dilated cardiomyopathy., Arthur M Feldman, Rene L Begay, Tijana Knezevic, Valerie D Myers, Dobromir B Slavov, Weizhong Zhu, Katherine Gowan, Sharon L Graw, Kenneth L Jones, Douglas G Tilley, Ryan C Coleman, Paul Walinsky, Joseph Y Cheung, Luisa Mestroni, Kamel Khalili, and Mathew R G Taylor

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The new oral anticoagulants for the treatment of venous thromboembolism: a new paradigm shift in antithrombotic therapy., Taki Galanis, Gina Keiffer, and Geno J Merli

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Then and now: the progress in hepatitis B treatment over the past 20 years., Dina Halegoua-De Marzio and Hie-Won Hann

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A long-term study of the effects of antiviral therapy on survival of patients with HBV-associated hepatocellular carcinoma (HCC) following local tumor ablation., Hie-Won Hann, Robert Coben, Daniel Brown, Laurence Needleman, Ernest Rosato, Albert Min, Richard Hann, Kyong Bin Park, Stephen Dunn, and Anthony J. DiMarino

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Usefulness of Highly Sensitive AFP-L3 and DCP in Surveillance for Hepatocellular Carcinoma in Patients with a Normal Alpha-Fetoprotein, Hie-Won Hann, Dave Li, Hiroyuki Yamada, Shinji Satomura, Robert Coben, and Anthony J. DiMarino

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Molecular and functional identification of a mitochondrial ryanodine receptor in neurons., Regina Jakob, Gisela Beutner, Virendra K Sharma, Yuntao Duan, Robert A Gross, Stephen Hurst, Bong Sook Jhun, Jin O-Uchi, and Shey-Shing Sheu

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Implementation of a Residency Twitter Account to Provide Curricular Enrichment, Bryan Lebude, MD; Subhashini Appulingam Sellers, MD; and Gretchen Diemer, MD, FACP

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Advances in the pathophysiology and treatment of heparin-induced thrombocytopenia., Steven E. McKenzie and Bruce S Sachais

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GATA3: a multispecific but potentially useful marker in surgical pathology: a systematic analysis of 2500 epithelial and nonepithelial tumors., Markku Miettinen, Peter McCue, Maarit Sarlomo-Rikala, Janusz Rys, Piotr Czapiewski, Krzysztof Wazny, Renata Langfort, Piotr Waloszczyk, Wojciech Biernat, Jerzy Lasota, and Zengfeng Wang

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The spectrum of eye disease in hospitalized adults living with HIV, 1995-2010., Christopher Miller; William Short, MD, MPH; Lorena Perez-Povis; Josephine Lontok; Christopher Fecarotta; Mengdan Liu; Jocelyn Sendecki; and Katherine Belden

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Adrenergic signaling regulates mitochondrial Ca2+ uptake through Pyk2-dependent tyrosine phosphorylation of the mitochondrial Ca2+ uniporter., Jin O-Uchi, Bong Sook Jhun, Shangcheng Xu, Stephen Hurst, Anna Raffaello, Xiaoyun Liu, Bing Yi, Huiliang Zhang, Polina Gross, Jyotsna Mishra, Alina Ainbinder, Sarah Kettlewell, Godfrey L Smith, Robert T Dirksen, Wang Wang, Rosario Rizzuto, and Shey-Shing Sheu

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Mitochondrial ion channels/transporters as sensors and regulators of cellular redox signaling., Jin O-Uchi, Shin-Young Ryu, Bong Sook Jhun, Stephen Hurst, and Shey-Shing Sheu

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Comparative effectiveness of less commonly used systemic monotherapies and common combination therapies for moderate to severe psoriasis in the clinical setting., Junko Takeshita, Shuwei Wang, Daniel B Shin, Kristina Callis Duffin, Gerald G Krueger, Robert E Kalb, Jamie D Weisman, Brian R Sperber, Michael B Stierstorfer, Bruce A Brod, Stephen M Schleicher, Andrew D Robertson, Kristin A Linn, Russell T Shinohara, Andrea B Troxel, Abby S Van Voorhees, and Joel M Gelfand

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Kallikrein family proteases KLK6 and KLK7 are potential early detection and diagnostic biomarkers for serous and papillary serous ovarian cancer subtypes., Ayala Tamir, Ushma Jag, Sreeja Sarojini, Craig Schindewolf, Takemi Tanaka, Rajendra Gharbaran, Hiren Patel, Anil Sood, Wei Hu, Ruzeen Patwa, Patrick Blake, Polina Chirina, Jin Oh Jeong, Heejin Lim, Andre Goy, Andrew Pecora, and K Stephen Suh

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Optimal Duration of Holter Recordings: Is there Additional Yield from 48 Versus 24 Hours?, Amanda Trang, MD and Behzad B. Pavri, MD

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Adiponectin inhibits tumor necrosis factor-α-induced vascular inflammatory response via caveolin-mediated ceramidase recruitment and activation., Yajing Wang, Xiaoliang Wang, Wayne Bond Lau, Yuexing Yuan, David Booth, Jing-Jing Li, Rosario Scalia, Kyle Preston, Erhe Gao, Walter Koch, and Xin-Liang Ma

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Blau Syndrome, the prototypic auto-inflammatory granulomatous disease., Carine H Wouters, Anne Maes, Kevin P Foley, John Bertin, and Carlos D Rose

Manuscripts from 2013

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Long-term persistency and costs associated with the use of iron chelation therapies in the treatment of Sickle cell disease within Medicaid programs., Edward P Armstrong, Grant H Skrepnek, Medha Sasane, Susan M Snodgrass, and Samir K. Ballas

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De Novo Fibrillary Glomerulonephritis (FGN) in a Renal Transplant with Chronic Hepatitis C., E J Filippone, Christine Chmielewski, Rakesh Gulati, Eric Newman, and John Farber

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The case for intervention bias in the practice of medicine., Andrew J Foy and E J Filippone

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Ectopic Cushing's Syndrome from ACTH-Producing Pheochromocytoma, Susan Gerber, MD; Lawrence C. Kenyon, MD, PhD; Mary Kate McCullen; and Serge Jabbour, MD, FACP, FACE

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Presumed Familial Late-Onset Medullary Thyroid Cancer in a patient with a germline point mutation, c. 2304 G->T, in RET proto-oncogene codon 768: specific mutation may guide timing of prophylactic total thyroidectomy in affected family members, Susan Gerber, MD; Madalina Tuluc, MD, PhD; and Serge Jabbour, MD, FACP, FACE

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Nuclear translocation of cardiac G protein-Coupled Receptor kinase 5 downstream of select Gq-activating hypertrophic ligands is a calmodulin-dependent process., Jessica I Gold, Jeffrey S Martini, Jonathan Hullmann, Erhe Gao, J Kurt Chuprun, Linda Lee, Douglas G Tilley, Joseph E Rabinowitz, Julie Bossuyt, Donald M Bers, and Walter J. Koch