Document Type
Article
Publication Date
12-1-2019
Abstract
Melanocytoma is a deeply pigmented variant of melanocytic nevus that classically occurs in the optic disk, sometimes with contiguous involvement of the adjacent retina or choroid. Historically, this tumor was often confused with malignant melanoma both clinically and histopathologically. Today, however, it is generally recognized by its typical clinical features that differ from most melanomas and erroneous enucleation is rarely done. Histopathologically, melanocytoma is composed of intensely pigmented round to oval nevus cells with benign features. Although traditionally believed to be a relatively stationary lesion, it is now known to exhibit minor enlargement in 10--15% of cases and can cause minor visual loss by a variety of mechanisms. In rare instance, it can induce severe visual loss due to spontaneous necrosis of the lesion or compressive optic neuropathy. More importantly, it can exhibit malignant transformation into melanoma in 1--2% of cases. Ophthalmologists should be familiar with melanocytoma of the optic disk and affected patients should be followed periodically.
Recommended Citation
Shields, Jerry A.; Demirci, Hakan; Mashayekhi, Arman; Eagle Jr., Ralph C.; and Shields, Carol L., "Melanocytoma of the optic disk: A review." (2019). Wills Eye Hospital Papers. Paper 104.
https://jdc.jefferson.edu/willsfp/104
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-Share Alike 4.0 License.
PubMed ID
31755427
Language
English
Comments
This article is the author’s final published version in Indian Journal of Ophthalmology, Volume 67, Issue 12, December 2019, Pages 1949-1958.
The published version is available at https://doi.org/10.4103/ijo.IJO_2039_19. Copyright © Shields et al.