The records are of print theses and dissertations between 1914-2012 with significant gap years.
To order a full-text copy of a dissertation:
1. Request a copy using inter-library loan services from a nearby library.
2. Request a visitor’s pass to the Scott Memorial Library and access print dissertation from collection. Use the library catalog to locate exact call number and location of dissertation.
3. Purchase a copy from UMI.
Questions? Contact: askalibrarian@jefferson.edu
Theses/Dissertations from 2012
Determining the role of toll-like receptors in innate and adaptive immune responses to borrelia hermsii and other antigenic targets of T cell-independent humoral immunity, Gregory S. Dickinson
Adaptation to ethanol dysregulates hepatic miRNA expression and alters the dynamic response of miRNAs during liver regeneration, Rachael P. Dippold
Harnessing the power of recombinant rabies viruses to make safer vaccines and study viral clearance from the brain, Emily A. Gomme
Nuclear and mitochondrial regulation of cellular differentiation: roles of serum response factor and tumor supressor p53, Nafeesa Hadiyah Hunt Owens
Nonclassical antigen processing and the implications for autoimmunity and infection, Tara M. Robinson
Gene-environment interactions and novel therapeutic interventions in prostate cancer, Supriya Shah
Theses/Dissertations from 2011
The impact of RB deficiency on hepatocyte biology and tumorigenesis, Ryan J. Bourgo
Arsenic-induced cell transformation and angiogenesis requires NADPH oxidase isoform 2-derived reactive oxygen species, Richard L. Carpenter
Prostaglandin D2 differentially regulates functions of human NK cell subsets through distinct receptors, Yingying Chen
MHC Class II restricted processing of endogenous antigens during viral infection, Joseph D. Comber
Therapeutic CDK46 inhibition in breast cancer and the importance of reestablishing cell cycle control through RB activation, Jeffry L. Dean
The effects of expression of thermolabile R789C and R992C collagen II mutants on cell behavior and extracellular matrix structure and function, Deborah Anne Jensen
A comparative analysis of human T cell responses to adenoviral early and late proteins, Amita Joshi
Antibiotic modification of nature's grafts: improving upon nature's scaffolds, Constantinos Ketonis
Characterization of a rat model of chronic headache, Christina R. Maxwell
Mechanisms of RETPTC 3-induced pro-inflammatory signaling, Robert John Neely
Gene expression studies of the VTA in an animal model of Parkinson's disease and the emergence of gremlin as a dopaminergic neuroprotective factor, Sudarshan Phani
Mechanisms of memory CD8+ T cell protection from an acuute lethal viral disease, Sanda S. Remakus
Insertional mutagenesis as a toll for identifying and characterizing novel candidate cancer genes, Jacquelyn Jinan Roth
Elucidation of MHC class II-restricted antigen processing pathways using influnenza epitopes, James S. Testa
Understanding the many facets of RETPTC oncogene activity in thyroid carcinoma: transformation, inflammation, and antigenicity, Josephine Fox Wixted
Theses/Dissertations from 2010
Analysis of B1b lymphocyte-mediated protective immunity, Matthew J. Colombo
A comprehensive analysis of interferon-beta's role in shaping the immunogenicity and pathogenicity of rabies virus:development of a novel vaccine vector, Elizabeth J. Faul
Multifunctional roles of lactate transporters in wound healing and metastasis, Shannon Gallagher-Colombo
Exploring p53 protein-proetin interactions as targets for chemotherapy, Soyoung Heo
N-Cadherin junction formation drives lens fiber cell differentiation and morphogenesis, Michelle Leonard
Double trouble: How simultaneous immune challenges can result in CNS disease, Christine Matullo
The use of adult adipose-derived stem cells in the creation of a tissue engineered vascular bypass graft, Stephen Edward McIlhenny
Caveolin-1 in human disease:the roles of Caveolin-1 in cancer and atherosclerosis, Stephanos Pavlides
Regulation of apoptosis by p53 and the Ecdysone receptor co-activator TRR in Drosophila, Kristen Marie Riley
Analysis of the function of FADD in hematopoietic stem cells, lineage development and hematopoietic function, Stephen M. Rosenberg
Regulation of meiotic development in Saccharomyces cerevisiae by the meiosis-specific Ime2 protein kinase, Marcus Shin
Biophysical and in vivo characterization of the dynein-dynactin interaction;implications for multiple modes of regulation, Amanda E. Siglin
Type I collagen-integrin interactions in angiogenesis, Kevin Turner
An intestinal prouroguanylin-hypothalamic GUCY2C axis mediates nutrient-induced satiety, Michael A. Valentino
A role for Myb in BCR-ABL(p190)-induced leukemogenesis:regulation of Arf suppression through transcriptional activation of BMI1, Todd J. Waldron
S100A1 competes with calmodulin for calmodulin binding proteins, CAV1.2 and SK2 channels, Kristen Metzler Wilson
Deletion of GSK-3B in vivo: revealing the role of this signal integrator in cardiomyocyte hypertrophy and proliferation, Kathleen Camille Woulfe
Guanylyl cyclase C remodels metastatic architecture through vasodilator-stimulated phosphoprotein, David S. Zuzga
Theses/Dissertations from 2009
Regulation of middle meiotic gene expression by the Sum1 repressor, Noreen T. Ahmed
Influence of opioid and estrogen systems on cocaine withdrawal in females, Lisa M. Ambrose-Lanci
Novel insights into arrestin mediated receptor trafficking, Ronald C. Kern
Regulation of the transcriptional repressor Sum1 by the meiosis-specific kinase Ime2 in Saccharomyces cerevisiae, Michael Moore
Molecular basis of aneuploidy:functions of the aurora kinases, Rad51c, and CREB binding protein in female meiosis, Kristy Shuda
Induction of the osteocytic phenotype:the influence of oxygen on bone cell maturation and survival, Adam M. Zahm
Perlecan coordinates developmental angiogenesis, Jason Joseph Zoeller
Theses/Dissertations from 2008
Approaches toward the investigation of T cell specificities and antigenic determinants in an MHC-matched mouse GVHD model, Michael Jay Appel
T cell-mediated cytotoxicity: understanding the mechanism of effective delivery of a poison pill, Allison M. Beal
In vivo analysis of cell-autonomous versus non-cell-autonomous contributions to neuronal dysfunction in disorders of the basal ganglia, Timothy B. Brown
Structure, folding and engineering of 5-Helix, a designed HIV-1 entry inhibitor, Kelly Champagne
Role of a polybasic motif in plasma membrane targeting and signaling of G-protein alpha subunits, Marykate Crouthamel
Investigating the role of the adenylyl cyclase inhibitory G protein alpha subunit (G-alpha-i2) in dysfunctional myocardium, Brent Robert DeGeorge
A novel integral voltage sensor-interacting protein:shedding light on the gating mechanisms of somatodendritic Kv channels, Kevin Joseph Dougherty
A new mechanism for transcriptional regulation by nuclear hormone receptors during Drosophila development, Danika M. Johnston
Uncovering G protein-coupled receptor kinase-5 as a novel histone deacetylase kinase, Jeffrey S. Martini
Pathogenicity determinants of rabies virus and their function in the pathogenesis of rabies, Rojjanaporn Poumanausahakul
Expression of Kv4 channels in dorsal root ganglion neurons:major determinants of the A-type potassium current, Thanawath Ratanadilok Na Phuket
Immune evasion by silver-haired bat rabies virus and implications for treatment, Anirban Roy
Targeting adrenergic receptors in the treatment of cocaine withdrawal-related anxiety, Carla Ann Rudoy
Theses/Dissertations from 2007
Upregulation of fetal hemoglobin in adult-derived erythroid progenitors, Bubu Ama Banini
Analysis of the molecular mechanisms underlying genomic maintenance in the malaria parasite Plasmodium Falciparum, Jeffrey S. Buguliskis
Insulin receptor substrate 1, a novel oncogene target in breast cancer, Gregory V. Cesarone
RGS-RhoGEFs: interactions with G proteins and identification of novel subcellular locations and functions, Elda Grabocka
IgH chain rearrangement in anti-DNA transgenic B cells, Kerstin Kiefer
Guanylyl cyclase C controls intestinal homeostatis and suppresses intestinal tumorigenesis, Peng Li
B lymphocyte adaptive tolerance: a learned ignorance pathway, Xiaohe Liu
Neutrophils and macrophages in the immune response to parasitic helminths, Amy O'Connell
Molecular physiology of voltage-gated sodium channels: a cation-PI interaction and voltage sensor movement, Vincent P. Santarelli
Guanylyl Cyclase C is a novel immunotherapeutic target for metastatic colorectal cancer, Adam E. Snook
The dynein light chain 8 binding motif of rabies virus phosphoprotein promotes efficient viral transcription, Gene S. Tan
Hypoxia inducible factor and prolyl hydrolase regulation of growth rate function, Shawn Patrick Terkhorn
Theses/Dissertations from 2006
Molecular characterization of adult human mesenchymal stem cell differentiation: the role of WNT signaling, Genevieve Marie Boland
Functions of the structure-specific metallonuclease flap endonuclease-1 in the Plasmodium falciparum DNA base excision repair pathway, Louis John Casta III
Expression and interactions of hMLH3 in DNA repair: , Nicole Rene Charbonneau
Analysis of T cell receptor alpha chain restriction during a CD4+ V-beta 11+ T cell against minor histocompatability antigens, Christine Gabriella DiRienzo
The function of C R E B - binding protein in germline development, Aaron Matthew Elliot
The CLCA family of calcium-activated chloride, Stella R. Evans
The oxemic environment of the nucleas pulposus and its mechanism of regulation, Deanna Candace Lee
Arrestin-2: structure and function, Shawn K. Milano
Mechanism of G protein-coupled receptor kinase binding and activation by G protein-coupled receptors, Christina S. Pao
Rabies virus as an immunostimulatory carrier molecule for vaccination against anthrax, Mary Ellen Smith
Kinetic restriction of HIV-1 entry inhibition, H Kirby Steger
An essential role for caspase-3 in osteoclast differentiation, Krystyna Helena Szymczyk
Survival and apoptotic-related signaling pathways regulate lens cell differentiation, Gregory F. Weber
Design, synthesis and analysis of ligands for guanylyl cyclase C, R Henry Wolfe
Theses/Dissertations from 2005
Modulation of glucocorticoid-induced apoptosis in acute lymphoblastic leukemia cells, Marc T. Abrams
The interactions of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) treatment and age with ganglioside therapy on the nigrostriatal dopamine system, David William Anderson
Bone cell survival in microgravity: the effects of vector-averaged gravity on the osteoblast, Michael A. Bucaro
Molecular-genetic analysis of the role of the RSC chromatin remodeling complex during sporulation in Saccharomyces cerevisiae, David Bungard
Androgen modulation alters phenotype and cellular pathology in a mouse model of spinal and bulbar muscular atrophy, Erica S. Chevalier-Larson
Regulation of CD4+ T cell responses to the hepatitus B core antigen, Jessica A. Chichester
Perturbation of oncogenic orthologs in zebrafish, Kevin T. Duffy
Myosin crossbridge kinetics and the mechanism of catch: single turnover of myosin-bound ADP in catch muscle, Aaron S. Franke
Guanylyl cyclase C activity inhibits colorectal carcinoma cell metastatic seeding of the lung by a matrix metalloproteinase-9-dependent mechanism, Wilhelm Johannes Lubbe
Analyses of FHIT Function in tumor suppression, cell cycle progression and DNA damage response, Kelly A. McCorkell
