Methemoglobinemia-Induced Cardiac Dysfunction in a Pediatric Patient

Authors

Brian Drury
Chelsea Boyd
Kelsey Van Housen, Thomas Jefferson UniversityFollow
Siraj Amanullah

Document Type

Report

Publication Date

10-7-2025

Comments

This article is the author’s final published version in Annals of Internal Medicine Clinical Cases, Volume 4, Issue 10, 2025, Article number e250671.

The published version is available at https://doi.org/10.7326/aimcc.2025.0671. Copyright © 2025 Authors.

Abstract

Methemoglobinemia is a rare congenital or acquired cause of functional anemia resulting from oxidation of hemoglobin. Prompt recognition and treatment are critical to prevent tissue hypoxia and end-organ injury. While other complications are well described, cardiac dysfunction is rarely reported—especially in children. We present what, to our knowledge, is the first known case of methemoglobinemia-induced transient cardiac dysfunction—or “myocardial stunning— in a pediatric patient. This case underscores the importance of maintaining a high index of suspicion and assessing cardiac involvement in such patients. Early intervention can lead to full recovery and prevent long-term sequelae, even in the presence of multiorgan failure

Recommended Citation

Drury, Brian; Boyd, Chelsea; Van Housen, Kelsey; and Amanullah, Siraj, "Methemoglobinemia-Induced Cardiac Dysfunction in a Pediatric Patient" (2025). Student Papers, Posters & Projects. Paper 178.
https://jdc.jefferson.edu/student_papers/178

Creative Commons License

This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.

Language

English