Document Type
Article
Publication Date
August 2007
Abstract
A novel and functional conjugative transfer system identified in O119:H2 enteropathogenic Escherichia coli (EPEC) strain MB80 by subtractive hybridization is encoded on a large multidrug resistance plasmid, distinct from the well-described EPEC adherence factor (EAF) plasmid. Variants of the MB80 conjugative resistance plasmid were identified in other EPEC strains, including the prototypical O111:NM strain B171, from which the EAF plasmid has been sequenced. This separate large plasmid and the selective advantage that it confers in the antibiotic era have been overlooked because it comigrates with the virulence plasmid on conventional gels.
Recommended Citation
Nwaneshiudu, Adaobi I.; Mucci, Tania; Pickard, Derek J.; and Okeke, Iruka N., "A second large plasmid encodes conjugative transfer and antimicrobial resistance in O119:H2 and some typical O111 enteropathogenic Escherichia coli strains" (2007). Student Papers, Posters & Projects. Paper 1.
https://jdc.jefferson.edu/student_papers/1
Table S2, BLAST hits for MB80 plasmid sample sequence runs; Table S3, primer table
Comments
This article has been peer reviewed. It was published in the Journal of Bacteriology 189(16):6074-6079, August 2007. The published version is available at http://dx.doi.org/10.1128/JB.00349-07. Copyright 2007 by the American Society for Microbiology, posted here by permission.