"Hypoalbuminemia and Postoperative Outcomes Following Major Salivary Gl" by Praneet C. Kaki, Aman M. Patel et al.
 

Document Type

Article

Publication Date

2-1-2025

Comments

This article is the author's final published version in Laryngoscope Investigative Otolaryngology, Volume 10, Issue 1, February 2025, Article number e70107.

The published version is available at https://doi.org/10.1002/lio2.70107.

Copyright © 2025 The Author(s)

Abstract

OBJECTIVE: Hypoalbuminemia (HA) is a proxy for malnutrition that has been associated with postoperative complications in several surgical subspecialties. This study investigates the association between pre-operative HA and complications following major salivary gland (MSG) resection.

METHODS: Patients undergoing outpatient, elective MSG resection were extracted from the 2005 to 2020 National Surgical Quality Improvement Program database. Demographics and comorbidities were compared between HA (preoperative serum albumin < 3.5 g/dL) and non-HA cohorts. To determine associations between albumin status and postoperative complications, univariate and multivariable binary logistic regression analyses were performed.

RESULTS: A total of 5774 patients undergoing MSG resection were included, of which 321 (5.6%) had preoperative HA. HA was associated with older age on univariate analysis (65.2 vs. 60.2 years,

CONCLUSION: Preoperative HA may be a poor prognostic factor associated with an increased risk of surgical complications and prolonged LOS among patients undergoing MSG resection.

LEVEL OF EVIDENCE: 4.

Creative Commons License

Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.

Language

English

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