Manuscripts from 2022


Progressive multifocal fibrosing neuropathy: description of a novel disease., Fabian A. Mendoza, Jennifer Bagley, Michael Gochfeld, Marinos Dalakas, John Farber, and Sergio A. Jimenez


Serine-threonine kinase inhibition as antifibrotic therapy: transforming growth factor-β and Rho kinase inhibitors, Fabian A. Mendoza and Sergio A. Jimenez

Manuscripts from 2013


Role of Endothelial to Mesenchymal Transition in the Pathogenesis of the Vascular Alterations in Systemic Sclerosis., Sergio A Jimenez

Manuscripts from 2012


Systemic sclerosis disease modification clinical trials design: quo vadis?, Fabian A. Mendoza, MD; Lynette L Keyes-Elstein; and Sergio A. Jimenez

Manuscripts from 2011


Scleroderma renal crisis-like acute renal failure associated with mucopolysaccharide accumulation in renal vessels in a patient with scleromyxedema., Young H Lee, Joya Sahu, Marie S O'Brien, Vivette D D'Agati, and Sergio A. Jimenez

Manuscripts from 2010


Biomarkers in systemic sclerosis., Susan V. Castro and Sergio A. Jimenez


Junctional adhesion molecule-A is abnormally expressed in diffuse cutaneous systemic sclerosis skin and mediates myeloid cell adhesion., Y Hou, B J Rabquer, M L Gerber, F Del Galdo, S A Jimenez, G K Haines, W G Barr, M C Massa, J R Seibold, and A E Koch

Manuscripts from 2009


Mechanism of NSF: New evidence challenging the prevailing theory, Ben B. Newton, PhD and Sergio A. Jimenez, MD

Manuscripts from 2008


Targeting NF-kappaB: a promising molecular therapy in inflammatory arthritis., Jorge A. Roman-Blas and Sergio A. Jimenez

Molecular ablation of TGF-beta signaling pathways by tyrosine kinase inhibition: The coming of a promising new era in the treatment of tissue fibrosis, Joel Rosenbloom and Sergio A. Jimenez

Documents from 2007

T cells expressing allograft inflammatory factor 1 display increased chemotaxis and induce a profibrotic phenotype in normal fibroblasts in vitro, Francesco Del Galdo and Sergio A. Jimenez

Regulation of the human SOX9 promoter by Sp1 and CREB, Sonsoles Piera-Velazquex, David F. Hawkins, Mary Kate Whitecavage, David C. Colter, Sergio A. Jimenez, and David A. Stokes

Modulation of TGF-β signaling by proinflammatory cytokines in articular chondrocytes, J A. Roman-Blas, D G. Stokes, and S. A. Jimenez

Documents from 2006

The role of allograft inflammatory factor 1 in systemic sclerosis, Francesco Del Galdo, Carol M. Artlett, and Sergio A. Jimenez

Expression of allograft inflammatory factor 1 in tissues from patients with systemic sclerosis and in vitro differential expression of its isoforms in response to transforming growth factor beta, Francesco Del Galdo, Gerd G. Maul, Sergio A. Jimenez, and Carol M. Artlett

Inhibition of systemic sclerosis dermal fibroblast type I collagen production and gene expression by simvastatin, Natalia Louneva, Gonzalo Huaman, Joanna Fertala, and Sergio A. Jimenez

Description of twelve cases of nephrogenic fibrosing dermopathy and review of the literature, Fabian A. Mendoza, Carol M. Artlett, Nora Sandorfi, Kevin Latinis, Sonoles Piera-Velazquez, and Sergio A. Jimenez

Documents from 2005

Inhibition of Collagen Gene Expression in Systemic Sclerosis Dermal Fibroblasts by Mithramycin, Nora Sandorfi, Natalia Louneva, Elena Hitraya, Gyorgy Hajnoczky, Biagio Saitta, and Sergio A. Jimenez

Documents from 2004


B-Myb acts as a repressor of human COL1A1 collagen gene expression by interacting with Sp1 and CBF factors in scleroderma fibroblasts, Lucia Cicchillitti, Sergio A. Jimenez, Arturo Sala, and Biaggio Saitta

Following the molecular pathways toward an understanding of the pathogenesis of systemic sclerosis, Chris T. Derk and Sergio A. Jimenez

Dialysis-associated systemic fibrosis (nephrogenic fibrosing dermopathy): study of inflammatory cells and transforming growth factor beta1 expression in affected skin, Sergio A. Jimenez, Carol M. Artlett, Nora Sandorfi, Chris T. Derk, Kevin Latinis, Heloisa Sawaya, Richard Haddad, and Joseph C. Shanahan

Documents from 2002

Inhibition of basal and transforming growth factor-beta-induced stimulation of COL1A1 transcription by the DNA intercalators, mitoxantrone and WP631, in cultured human dermal fibroblasts, Svetlana Gaidarova and Sergio A. Jimenez

Documents from 2001


Role of protein kinase C-delta in the regulation of collagen gene expression in scleroderma fibroblasts, Sergio A. Jimenez, Svetlana Gaidarova, Biagio Saitta, Nora Sandorfi, David J. Herrich, Joan C. Rosenbloom, Umberto Kucich, William R. Abrams, and Joel Rosenbloom


Regulation of type-II collagen gene expression during human chondrocyte de-differentiation and recovery of chondrocyte-specific phenotype in culture involves Sry-type high-mobility-group box (SOX) transcription factors, David G. Stokes, Gang Liu, Rita Dharmavaram, David Hawkins, Sonsoles Piera-Velazquez, and Sergio A. Jimenez

Documents from 2000

Detection of cellular microchimerism of male or female origin in systemic sclerosis patients by polymerase chain reaction analysis of HLA-Cw antigens, Carol M. Artlett, Lori A. Cox, and Sergio A. Jimenez

CCAAT binding transcription factor binds and regulates human COL1A1 promoter activity in human dermal fibroblasts: demonstration of increased binding in systemic sclerosis fibroblasts, Biagio Saitta, Svetlana Gaidarova, Lucia Cicchillitti, and Sergio A. Jimenez

Documents from 1999

Lack of endothelial cell apoptosis in the dermis of tight skin 1 and tight skin 2 mice, Roswitha Sgonc, Hermann Deitrich, Claudia Sieberer, Georg Wick, Paul J. Christner, and Sergio A. Jimenez

Documents from 1998

Modulation of basal expression of the human alpha1(I) procollagen gene (COL1A1) by tandem NF-1/Sp1 promoter elements in normal human dermal fibroblasts, Carol M. Artlett, Shu-Jen Chen, John Varga, and Sergio A. Jimenez


Identification of fetal DNA and cells in skin lesions from women with systemic sclerosis, Carol M. Artlett, J. Bruce Smith, and Sergio A. Jimenez

Identification of elements in the promoter region of the alpha1(I) procollagen gene involved in its up-regulated expression in systemic sclerosis, Elena G. Hitraya, John Varga, Carol M. Artlett, and Sergio A. Jimenez

Documents from 1997

Fetal-maternal HLA compatibility confers susceptibility to systemic sclerosis, Carol Artlett, Ken I. Welsh, Carol M. Black, and Sergio A. Jimenez

Documents from 1996

Transcriptional activation of the alpha 1(I) procollagen gene in systemic sclerosis dermal fibroblasts:. Role of intronic sequences., Elena G. Hitraya and Sergio A. Jimenez

Documents from 1995


Stimulation of alpha 1(I) procollagen gene expression in NIH-3T3 cells by the human T cell leukemia virus type 1 (HTLV-1) tax gene., E. Munoz, D. Suri, S. Amini, K. Khalili, and Sergio A. Jimenez

Documents from 1993


The tight skin mouse: demonstration of mutant fibrillin-1 production and assembly into abnormal microfibrils, Cay M. Kielty, Michael Raghunath, Linda D. Siracusa, Michael J. Sherratt, Reiner Peters, C. Adrian Shuttleworth, and Sergio A. Jimenez