Document Type
Article
Publication Date
3-17-2022
Abstract
Individuals eligible for lung cancer screening (LCS) are at risk for atherosclerotic cardiovascular disease (ASCVD) due to smoking history. Coronary artery calcifications (CAC), a common incidental finding on low-dose CT (LDCT) for LCS, is a predictor of cardiovascular events. Despite findings of high ASCVD risk and CAC, a substantial proportion of LCS patients are not prescribed primary preventive statin therapy for ASCVD. We assessed the frequency of statin prescription in LCS patients with moderate levels of CAC. Among 259 individuals with moderate CAC, 95% had ASCVD risk ≥ 7.5%. Despite this, 27% of patients were statin-free prior to LDCT and 21.2% remained statin-free after LDCT showing moderate CAC. Illustratively, while a substantial proportion of LCS patients are statin-eligible, many lack a statin prescription, even after findings of CAC burden. CAC reporting should be standardized, and interdisciplinary communication should be optimized to ensure that LCS patients are placed on appropriate preventive therapy.
Recommended Citation
Majeed, Amry; Ruane, Brooke; Shusted, Christine S; Austin, Melissa; Mirzozoda, Khulkar; Pimpinelli, Marcella; Vojnika, Jetmir; Ward, Lawrence; Sundaram, Baskaran; Lakhani, Paras; Kane, Gregory C. MD; Lev, MD, Yair; and Barta, MD, Julie, "Frequency of Statin Prescription Among Individuals with Coronary Artery Calcifications Detected Through Lung Cancer Screening." (2022). Division of Pulmonary and Critical Care Medicine Faculty Papers. Paper 23.
https://jdc.jefferson.edu/pulmcritcarefp/23
PubMed ID
35302536
Language
English
Comments
This is the accepted manuscript version of the article from The American Journal of Medical Quality, 2022 Mar 17.
The final published version of the article can be found at the journal's website: https://doi.org/10.1097/JMQ.0000000000000053