Document Type
Abstract
Publication Date
5-1-2018
Abstract
Recent reclassification of a subset of non-invasive encapsulated follicular variant of papillary thyroid carcinoma (EFVPTC) tumors as non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) has led to important changes in the clinical management of patients with these indolent lesions. Although there are established diagnostic criteria to differentiate NIFTP from EFVPTC, our objective was to determine further differences in histological characteristics between NIFTP and noninvasive EFVPTC. Additionally, we sought to identify histological differences between non-invasive and invasive EFVPTC lesions beyond the key finding of invasion. 68 encapsulated follicular lesions with papillary-like nuclear features from patients treated at Thomas Jefferson University Hospital were subcategorized into NIFTP, non-invasive EFVPTC, and invasive EFVPTC based on current diagnostic criteria. Histological characteristics such as capsule thickness, lesion size, fibrosis, and presence of established exclusionary criteria for NIFTP were recorded. Capsule thickness was significantly smaller in NIFTP (p
Recommended Citation
French, Brenda and Mardekian, MD, Stacey K., "Comparative analysis of tumor capsule thickness and other histologic features in encapsulated follicular variant of papillary thyroid carcinoma (EFVPTC) and noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP)" (2018). Department of Pathology Honors Program Student Research Symposium. Poster 43.https://jdc.jefferson.edu/phsrs/43
Language
English
Comments
Honors Program Student Research Symposium (April, 2018)
Sidney Kimmel Medical College, Department of Pathology, Anatomy & Cell Biology
Stephen Peiper, MD, Chair
Program Coordinators: Casey Callahan, BS & Bruce Fenderson, PhD
Funding provided by the "Intersociety Council for Pathology Information"