The Intersection Between HPV and HIV Infections: Is There an Increased Susceptibility to HIV Acquisition in HPV-Infected Women?

Authors

Montida Fleming, BA, Jefferson Medical CollegeFollow
Fred Gorstein, MD, Dept of Pathology, Anatomy and Cell Biology, JMC, Thomas Jefferson University, Philadelphia, PAFollow

Document Type

Poster

Publication Date

6-2014

Abstract

It has been well documented that HIV infection is associated with HPV infection and the progression to cervical carcinoma. Since the spread of HIV/AIDS epidemic, HPV-related cervical carcinoma had such a high prevalence in HIV-infected individuals that it became established as an AIDS-defining illness. Cervical cancer is the most common AIDS-related malignancy, and the sixth most common presenting AIDS-defining illness in women.¹ Additionally, HIV infection leads to a 5-fold increase in multiple new HPV infections within 6 weeks of seroconversion.² Not only does HIV impact acquisition of HPV at molecular and cellular levels, HIV and HPV viruses interact in complex ways such that each enhances the acquisition and amplification of the other.

Recommended Citation

Fleming, BA, Montida and Gorstein, MD, Fred, "The Intersection Between HPV and HIV Infections: Is There an Increased Susceptibility to HIV Acquisition in HPV-Infected Women?" (2014). Department of Pathology Honors Program Student Research Symposium. Poster 20.
https://jdc.jefferson.edu/phsrs/20