Is Myeloproliferative Neoplasm with Splanchnic Vein Thrombosis a Distinct Clinical Entity?

Authors

Upasana Joneja, MD, Thomas Jefferson University Hospital, Philadelphia, PAFollow
Jerald Z. Gong, MD, Thomas Jefferson UniversityFollow
Guldeep Uppal, MD, Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson UniversityFollow

Document Type

Poster

Publication Date

2015

Abstract

Clinical History:

A 29 year-old previously healthy female presented with sub-acute symptoms of weight loss, right upper quadrant pain and nausea.

CBC results: WBC-11.7, Hb- 12.5, Platelet- 286, MCV- 90, MCV- 26.8, RDW- 18%.

Imaging: Ultrasound and MRI of the abdomen were suggestive of Budd-Chiari syndrome that was supported by a liver biopsy showing features of hepatic outflow obstruction(Figure 1). There was no clinical or radiological evidence of splenomegaly. The hypercoagulable work-up was negative. An underlying Myeloproliferative Neoplasm (MPN) was suspected.

Recommended Citation

Joneja, MD, Upasana; Gong, MD, Jerald Z.; and Uppal, MD, Guldeep, "Is Myeloproliferative Neoplasm with Splanchnic Vein Thrombosis a Distinct Clinical Entity?" (2015). Department of Pathology, Anatomy, and Cell Biology Resident's Posters. Paper 15.
https://jdc.jefferson.edu/pacbresidentposters/15