Aberrant CD56 expression on granulocytes is seen in all aubtypes MPN and high grade MDS. CD56 expression in MPN correlated with bone marrow morphology, BCR/ABL transcript, and bone marrow engraftment study following treatment. Identification of abnormal CD56+ granulocytes and monocytes is helpful in both the initial diagnosis and long-term follow up of patients with MPN and MDS.
Gong, MD, Ping; Metrebian, MD, Fernanco; Dulau-Florea, MD, Alina; Wang, PhD, Zi-Xuan; Bajaj, PhD, Renu; Peiper, Stephen C; and Gong, MD, Jerald Z., "Aberrant expression of CD56 on granulocytes and monocytes in myeloproliferative neoplasm and myelodysplastic syndrome" (2012). Department of Pathology, Anatomy, and Cell Biology Faculty Papers. Paper 81.