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Otorrhea is the most common complication following tympanostomy tube placement, with an incidence commonly reported at around 20%. Topical otic antibiotic drops are typically used for relief of otorrhea in children with tympanostomy tubes. In children with recurrent otorrhea, gastroesophageal reflux and extraesophageal reflux have been postulated to be involved in the pathogenesis of otitis media with effusion1. Middle ear inflammation is thought to be mediated by proteolytic activity of pepsin, as well as by the decrease in pH associated with reflux of gastric acid through Eustachian tube. The goal of this study is to examine the presence of pepsin in post-tympanostomy tube otorrhea.
Poster presented at: Pennsylvania Academy of Otolaryngology in Bedford PA.
Gastric Pepsin in Post-Tympanostomy Tube Otorrhea
D'Souza, MD, Jill N.; Fields, PA-C, Erin; He, PhD, Zhaoping; and Reilly, MD, Robert O', "Gastric Pepsin in Post-Tympanostomy Tube Otorrhea" (2016). Department of Otolaryngology-Head and Neck Surgery Posters. 5.