Gastric Pepsin in Post-Tympanostomy Tube Otorrhea

Authors

Jill N. D'Souza, MD, Department of Otolaryngology-Head and Neck Surgery, Thomas Jefferson University, Philadelphia PAFollow
Erin Fields, PA-C, Division of Pediatric Otolaryngology, Nemours/A.I. DuPont Hospital for Children, Wilmington, DE
Zhaoping He, PhD, Division of Biomedical Research, Nemours/A.I. DuPont Hospital for Children, Wilmington, DE
Robert O' Reilly, MD, Division of Pediatric Otolaryngology, Nemours/A.I. DuPont Hospital for Children, Wilmington, DE

Files

Description

Introduction

Otorrhea is the most common complication following tympanostomy tube placement, with an incidence commonly reported at around 20%. Topical otic antibiotic drops are typically used for relief of otorrhea in children with tympanostomy tubes. In children with recurrent otorrhea, gastroesophageal reflux and extraesophageal reflux have been postulated to be involved in the pathogenesis of otitis media with effusion¹. Middle ear inflammation is thought to be mediated by proteolytic activity of pepsin, as well as by the decrease in pH associated with reflux of gastric acid through Eustachian tube. The goal of this study is to examine the presence of pepsin in post-tympanostomy tube otorrhea.

Poster presented at: Pennsylvania Academy of Otolaryngology in Bedford PA.

Publication Date

6-17-2016

Keywords

Gastric Pepsin in Post-Tympanostomy Tube Otorrhea

Disciplines

Otolaryngology

Recommended Citation

D'Souza, MD, Jill N.; Fields, PA-C, Erin; He, PhD, Zhaoping; and Reilly, MD, Robert O', "Gastric Pepsin in Post-Tympanostomy Tube Otorrhea" (2016). Department of Otolaryngology - Head and Neck Surgery Posters. 5.
https://jdc.jefferson.edu/otoposters/5