Marine-Lenhart Harboring Papillary Thyroid Cancer

Authors

Brian Y. Chou, MD, Endocrinology, Thomas Jefferson UniversityFollow
Sharon Segal, DO, Radiology, Thomas Jefferson UniversityFollow
Edmund A. Pribitkin, MD, Otolaryngology, Thomas Jefferson UniversityFollow
Jeffery L. Miller, MD, Endocrinology, Thomas Jefferson UniversityFollow

Document Type

Poster

Publication Date

7-11-2013

Comments

Presented at: 2nd World Congress on Thyroid Cancer in Toronto Canada.

Abstract

Introduction

Graves' disease with functioning nodules is referred to as Marine-Lenhart Syndrome. Only 2.7% of the patients with Graves’disease have concomitant functioning nodules.¹ Thyroid scintigraphy often definitively confirms the diagnosis. However, in addition to a hyperfunctioning (i.e. "hot") nodule, the thyroid scan may reveal isofunctioning (i.e. "warm"), and or a nonfuntioning (i.e. "cold") nodule as compared to the normal surrounding thyroid. Since hyperfuntioning nodules rarely harbor malignancy, if one is found that corresponds to the nodule in question, no cytologic evaluation is usually necessary.² Conversely, the majority of all nonfunctioning nodules may be benign or less frequently malignant, thus requiring cytopathologic evaluation.² We report a patient with Marine-Lenhart syndrome with the dilemma of a “hot “nodule found on thyroid scintigraphy which had “suspicious” ultrasonographic features prompting thyroidectomy after cytological diagnosis of papillary thyroid cancer (PTC). In this case, the utilization of neck ultrasonography provided significant risk stratifying data to support appropriate management.

Recommended Citation

Chou, MD, Brian Y.; Segal, DO, Sharon; Pribitkin, MD, Edmund A.; and Miller, MD, Jeffery L., "Marine-Lenhart Harboring Papillary Thyroid Cancer" (2013). Department of Otolaryngology - Head and Neck Surgery Presentations and Grand Rounds. Presentation 21.
https://jdc.jefferson.edu/otograndrounds/21