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The aim of this case series, is to describe our surgical technique for reconstructing benign mandibular neoplasms using BMAC – a less invasive approach than traditional iliac crest bone graft harvest.

BMAC was used in combination with mineralized freeze-dried allograft, platelet rich plasma (PRP) & bone morphogenic protein (rhBMP-2) to reconstruct the hard tissue lost secondary to the ablative tumor resection.

  • 10 patients included in the retrospective case series were treated between 2014 and 2017 by 3 surgeons.
  • Mean age - 44 years (range - 19 to 77 years). BMAC was obtained from the anterior iliac crest (AIC).
  • When appropriate, a custom milled mandibular reconstruction plate was placed.
  • Maxillofacial pathology included benign neoplasms such as Ameloblastoma, Cavernous Hemangioma, Central Giant Cell Granuloma (CGCG), Dentigerous Cyst & Keratocystic Odontogenic Tumor (KOT).

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bone marrow aspirate concentrate, anterior iliac crest, mandible, pathology, reconstruction


Dentistry | Oral and Maxillofacial Surgery

Reconstruction of Marginal Mandibular Defects Utilizing Bone Marrow Aspirate Concentrate (BMAC) from the Anterior Iliac Crest: A Less Morbid Osteogenic Option