Reconstruction of Marginal Mandibular Defects Utilizing Bone Marrow Aspirate Concentrate (BMAC) from the Anterior Iliac Crest: A Less Morbid Osteogenic Option

Authors

Shachika Khanna, BDS, DMD, Thomas Jefferson UniversityFollow
Rafael Gavilanes, DMD, Thomas Jefferson UniversityFollow
Robert Diecidue, DMD, MD, MBA, MSPH, Thomas Jefferson UniversityFollow
Daniel Taub, DDS, MD, Thomas Jefferson UniversityFollow
Alyssa Flashburg, DMD, Thomas Jefferson UniversityFollow

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Description

The aim of this case series, is to describe our surgical technique for reconstructing benign mandibular neoplasms using BMAC – a less invasive approach than traditional iliac crest bone graft harvest.

BMAC was used in combination with mineralized freeze-dried allograft, platelet rich plasma (PRP) & bone morphogenic protein (rhBMP-2) to reconstruct the hard tissue lost secondary to the ablative tumor resection.

• 10 patients included in the retrospective case series were treated between 2014 and 2017 by 3 surgeons.
• Mean age - 44 years (range - 19 to 77 years). BMAC was obtained from the anterior iliac crest (AIC).
• When appropriate, a custom milled mandibular reconstruction plate was placed.
• Maxillofacial pathology included benign neoplasms such as Ameloblastoma, Cavernous Hemangioma, Central Giant Cell Granuloma (CGCG), Dentigerous Cyst & Keratocystic Odontogenic Tumor (KOT).

Publication Date

2019

Keywords

bone marrow aspirate concentrate, anterior iliac crest, mandible, pathology, reconstruction

Disciplines

Dentistry | Oral and Maxillofacial Surgery

Recommended Citation

Khanna, BDS, DMD, Shachika; Gavilanes, DMD, Rafael; Diecidue, DMD, MD, MBA, MSPH, Robert; Taub, DDS, MD, Daniel; and Flashburg, DMD, Alyssa, "Reconstruction of Marginal Mandibular Defects Utilizing Bone Marrow Aspirate Concentrate (BMAC) from the Anterior Iliac Crest: A Less Morbid Osteogenic Option" (2019). Department of Oral and Maxillofacial Surgery Posters. 2.
https://jdc.jefferson.edu/omsposters/2