Document Type
Report
Publication Date
6-1-2025
Abstract
Osteolytic lesions of the mandibular condyle can represent a diverse range of differential diagnoses, including malignancies such as metastatic disease, Langerhans cell histiocytosis (LCH), osteosarcoma, chondrosarcoma, and multiple myeloma. This case report details a 40-year-old male with a 3-year history of right temporomandibular joint (TMJ) pain, initially misdiagnosed as temporomandibular disorder. Comprehensive imaging studies, including cone beam computed tomography (CBCT), maxillofacial computed tomography (CT), and brain magnetic resonance imaging (MRI), revealed extensive osteolytic lesions in the mandible, frontal bone, and cervical spine. A CT-guided biopsy confirmed the presence of a plasma cell neoplasm, leading to the diagnosis of multiple myeloma. This case report emphasizes the need for vigilance and comprehensive diagnostic approaches in clinical practice to avoid delays in the identification and treatment of serious underlying conditions such as malignancy.
Recommended Citation
Capobianco, Connor; Padilla, Mariella; Cho, Jungsuk; and Levi, Lauren, "Multiple Myeloma Presenting as an Ill-Defined Osteolytic Lesion of the Mandibular Condyle: A Case Report and Literature Review" (2025). Department of Oral and Maxillofacial Surgery Faculty Papers. Paper 6.
https://jdc.jefferson.edu/omsfp/6
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.
Language
English
Comments
This article is the author's final published version in Oral and Maxillofacial Surgery Cases, Volume 11, Issue 2, 2025, Article number 100394.
The published version is available at https://doi.org/10.1016/j.omsc.2025.100394.
Copyright © 2025 The Authors