Document Type
Article
Publication Date
12-5-2022
Abstract
BACKGROUND
Anaplastic meningioma are rare, cancerous tumors of the central nervous system that often require multimodal therapy for tumor control. Both laser interstitial thermal therapy (LITT) and brachytherapy with implanted cesium-131 metallic seeds have demonstrated efficacy in the treatment of recurrent and resistant anaplastic meningioma; however, their safety as a dual therapy has never been reported.
OBSERVATIONS
In this report, the authors present a case of a 53-year-old female who received LITT in combination with brachytherapy after surgical and radiation treatment options had been exhausted. The authors discuss the unique safety concern of thermal injury with this treatment combination and demonstrate their method for the safe administration of these treatments together. Furthermore, the authors provide a review of the literature on LITT as an emerging therapy for anaplastic meningioma.
LESSONS
The use of LITT in combination with brachytherapy remains an option for salvage therapy in patients with recurrent meningioma that provides durable local control of tumor.
Recommended Citation
Yudkoff, Clifford; Mahtabfar, Aria; Piper, Keenan; and Judy, Kevin, "Safety and Efficacy of Salvage Therapy With Laser Interstitial Thermal Therapy for Malignant Meningioma Refractory to Cesium-131 Brachytherapy: Illustrative Case" (2022). Department of Neurosurgery Faculty Papers. Paper 208.
https://jdc.jefferson.edu/neurosurgeryfp/208
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.
Language
English
Comments
This article is the author's final published version in journal of Neurosurgery Case Lessons, Volume 4, Issue 23, December 2022, Article number CASE22379.
The published version is available at https://doi.org/10.3171/CASE22379. Copyright © 2022 The authors.