The Clinical and Economic Value of Temporary Transvenous Diaphragm Pacing Systems for Mechanically Ventilated Patients in the U.S. Healthcare System

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Publication Date

11-7-2023

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Presentation: 18:55

Abstract

Various complications and high healthcare costs are often associated with patients on Invasive Mechanical Ventilation (IMV). Temporary Transvenous Diaphragm Pacing Systems (DPS) is an emerging technology that utilizes neuromuscular electrical stimulation to contract the diaphragm muscle providing additional respiratory support to patients on IMV. Research has shown the combined use of DPS and IMV can improve outcomes for this patient population. The purpose of the study was to accentuate the clinical and economic value of DPS, identify the unmet needs of the patient population, and provide strategies to generate the missing evidence. A scoping review identified a total of 8 articles outlining current knowledge of the clinical and economic value of DPS in IMV patients in the US. Results showed DPS helps mitigate the development of ventilator-induced diaphragmatic dysfunction (VIDD) and improves diaphragm muscle strength and respiration function. No formal economic evidence could be found; however, literature suggests DPS could reduce acute hospital costs. Additional studies are therefore recommended to understand the full clinical and economic benefits of DPS. Clinical studies should further explore dosing regime and DPS efficacy in pediatric patients. Economic evaluations are needed to better understand the economic implications of DPS in the US healthcare system, which should include but are not limited to a retrospective observational study to evaluate DPS costs and a budget impact analysis (BIA) from a payer perspective. These studies should be able to generate robust evidence to provide decision makers with a better assessment of the value of DPS in the US healthcare system.

Language

English

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