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Publication Date

6-28-2024

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Presentation: 6:41

Poster attached as supplemental file below

Abstract

This rapid systematic review synthesizes current evidence on interventions aimed at increasing clinical trial participation among people categorized as racial and ethnic minorities. Underrepresentation in clinical research perpetuates healthcare disparities, limiting the generalizability of study findings and exacerbating inequities in healthcare outcomes. The review adhered to PRISMA guidelines and included studies from 2018 to 2023 that focused on interventions targeting people recognized as African American, Hispanic/Latinx, and Asian communities in the United States. Six studies met inclusion criteria, using community-based outreach, culturally tailored education, faith-based initiatives, and decision aids. Findings underscored the importance of culturally sensitive approaches and community engagement in improving knowledge, trust, and willingness to participate in clinical trials among these populations. However, challenges such as historical mistrust and logistical barriers persist, necessitating multifaceted strategies to promote equitable research participation.

Lay Summary

This study investigates how to increase the involvement of people who are categorized as African American, Hispanic/Latinx, and Asian communities in clinical trials. These groups are often underrepresented, leading to gaps in healthcare knowledge and services. The review identified effective strategies used from 2018 to 2023, including community events, educational programs, and partnerships with faith-based organizations. These efforts aim to build trust and awareness about clinical research. While these interventions show promise, barriers like mistrust and logistical issues remain. Moving forward, it is crucial to continue developing approaches that respect cultural differences and actively involve communities in research processes. By doing so, we can improve healthcare outcomes for everyone.

Additional Files
202406_Aloba_Tolulope_poster.pptx (442 kB)

Language

English

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