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Publication Date

12-8-2017

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Advisor: Amy Leader, Jefferson College of Population Health, Jefferson University, Philadelphia, PA

Abstract

As the population in the United States becomes older and more diversified, conducting research that produces generalizable results has gained momentum, specifically pertaining to Alzheimer’s disease (AD). Considering that African Americans are twice as likely as whites to be affected by AD, proper recruitment into research studies is vital for generalizable results. A secondary data analysis was performed on survey responses from 207 elderly African Americans aged 65 and older. The survey responses were collected during the recruitment process for a clinical trial regarding cognitive decline and it assessed attitudes about and motivations for participating in a clinical trial. Means, frequencies, and ANOVAs were used to investigate differences among subpopulations. Additionally, interviews with two community health workers who were affiliated with the original study complimented the quantitative data. The interviews were transcribed verbatim to deduce common themes and important quotations. The results showed that individuals mainly participated in hopes to better their memory and to do good for others. The least compelling reason to participate was the financial incentive. There were also significant differences concerning gender, the ability to pay for necessities, and depression on the survey items. Furthermore, the interviews confirmed that trust and access were major barriers to research participation, and establishing a good rapport with the individuals was the most important facilitator. Knowing the barriers and facilitators to research participation can be utilized to increase clinical trial participation by African Americans regarding cognitive decline. By increasing research participation, results can be applied to this high-risk population to help combat this health disparity.

Presentation: 5:24

Language

English

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