Document Type
Article
Publication Date
9-6-2024
Abstract
The Patient-Centered Outcomes Research Institute (PCORI) funded multiple large-scale comparative effectiveness clinical trials evaluating palliative care (PC) and advance care planning (ACP) healthcare delivery models. This article provides an overview of the most common barriers our investigative teams encountered while implementing these trials and the strategies we utilized to overcome these challenges, with particular attention to identifying research partners for multisite trials; addressing contracting and regulatory issues; creating a team governance structure; training and engaging study staff across sites; recruiting, consenting, and enrolling study participants; collecting PC and ACP data and study outcomes; and managing multisite collaborations. The goal of this article is to provide guidance on how to best plan for and conduct rigorous trials evaluating PC and ACP healthcare delivery interventions moving forward.
Recommended Citation
El-Jawahri, Areej; Waterman, Brittany; Enguidanos, Susan; Gibbs, Lisa; Navarro, Victor; Olsen, Maren; Temel, Jennifer; Totten, Annette; and Grudzen, Corita R., "Conducting Comparative Effectiveness, Multisite Palliative Care and Advance Care Planning Trials: Lessons Learned and Future Directions from PCORI-Funded Studies" (2024). Department of Medicine Faculty Papers. Paper 467.
https://jdc.jefferson.edu/medfp/467
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.
Language
English
Comments
This article is the author's final published version in Medical Care, Volume 62, Issue 10, October 2024, pages 671-679.
The published version is available at https://doi.org/10.1097/MLR.0000000000002042.
Copyright © 2024 The Author(s).