Submissions from 2024


Correlation between Melphalan Chemotherapy with Longitudinal Global Strain Indices of the Left Ventricle in Multiple Myeloma Patients: A Velocity Vector Imaging (VVI) Echocardiography Study, Liaosadat Mirsafaee, Mohammad Dehghani Firouzabadi, Sayeh Parkhideh, Hassan Vahidnezhad, Fatemeh Dehghani Firouzabadi, Maryam Arab, David M. Yousem, and Mersedeh Karvandi

Submissions from 2023


Normal Values of Nerve Conduction Studies in Children Aged 7 Days to 14 Years Referred to Electrodiagnosis Clinic of Iranian Children’s Medical Center, Masood Ghahvechi Akbari, Fazel Mahmoodpoor, Mahmoodreza Ashrafi, Elahe Rezaee, Sahar Ghorbanpour, Seyede Zahra Emami Razavi, Mohaddeseh Azadvari, Reza Shervin Badv, Gholamreza Zamani, Ali Reza Tavasoli, Morteza Heidari, Zahra Rezaei, Setareh Rohani, and Mahmoud Mohammadi

Submissions from 2022


Advance Trends in Targeting Homology-Directed Repair for Accurate Gene Editing: An Inclusive Review of Small Molecules and Modified CRISPR-Cas9 Systems, Forough Shams, Hadi Bayat, Omid Mohammadian, Somayeh Mahboudi, Hassan Vahidnezhad, Mohsen Soosanabadi, and Azam Rahimpour

Submissions from 2020


Health Assessment Questionnaire-Disability Index (HAQ-DI) use in modelling disease progression in diffuse cutaneous systemic sclerosis: an analysis from the EUSTAR database., Yannick Allanore, Sylvie Bozzi, Augustin Terlinden, Doerte Huscher, Caroline Amand, Christina Soubrane, Elise Siegert, László Czirják, Patricia E Carreira, Eric Hachulla, Elisabetta Zanatta, Mengtao Li, Paolo Airò, Fabian A Mendoza, Edoardo Rosato, and Oliver Distler

Submissions from 2018


Abrogation of transforming growth factor-β-induced tissue fibrosis in TBRIcaCol1a2Cre transgenic mice by the second generation tyrosine kinase inhibitor SKI-606 (Bosutinib)., Peter J. Wermuth and Sergio A. Jimenez

Submissions from 2016


Endothelial to Mesenchymal Transition (EndoMT) in the Pathogenesis of Human Fibrotic Diseases., Sonsoles Piera-Velazquez, Fabian A. Mendoza, and Sergio A. Jimenez

Submissions from 2015


The significance of macrophage polarization subtypes for animal models of tissue fibrosis and human fibrotic diseases., Peter J. Wermuth and Sergio A. Jimenez

Submissions from 2014


Induction of a type I interferon signature in normal human monocytes by gadolinium-based contrast agents: comparison of linear and macrocyclic agents., Peter J. Wermuth and Sergio A. Jimenez

Submissions from 2013


Caveolin-1 deficiency induces spontaneous endothelial-to-mesenchymal transition in murine pulmonary endothelial cells in vitro., zhaodong Li, Peter J. Wermuth, Bryan S. Benn, Michael P. Lisanti, and Sergio A. Jimenez


Strategies for anti-fibrotic therapies., Joel Rosenbloom; Fabian A. Mendoza, MD; and Sergio A. Jimenez

Submissions from 2012


Severe eosinophilic syndrome associated with the use of probiotic supplements: a new entity?, Fabian A Mendoza, Shivani Purohit, Lawrence C. Kenyon, and Sergio A. Jimenez


A prospective observational study of mycophenolate mofetil treatment in progressive diffuse cutaneous systemic sclerosis of recent onset., Fabian A. Mendoza, MD; Sarah J. Nagle; Jason B. Lee, MD; and Sergio A. Jimenez


Molecular mechanisms of endothelial to mesenchymal cell transition (EndoMT) in experimentally induced fibrotic diseases., Sonsoles Piera-Velazquez and Sergio A. Jimenez

Submissions from 2011


Effect of protein kinase C delta (PKC-δ) inhibition on the transcriptome of normal and systemic sclerosis human dermal fibroblasts in vitro., Peter J Wermuth, Sankar Addya, and Sergio A Jimenez

Submissions from 2010


Assessment of tissue fibrosis in skin biopsies from patients with systemic sclerosis employing confocal laser scanning microscopy: an objective outcome measure for clinical trials?, Joanna Busquets, Francesco Del Galdo, Eugene Y. Kissin, and Sergio A. Jimenez


Biomarkers in systemic sclerosis., Susan V. Castro and Sergio A. Jimenez


NFκB activation and stimulation of chemokine production in normal human macrophages by the gadolinium-based magnetic resonance contrast agent Omniscan: possible role in the pathogenesis of nephrogenic systemic fibrosis., Francesco Del Galdo, Peter J Wermuth, Sankar Addya, Paolo Fortina, and Sergio A Jimenez


Junctional adhesion molecule-A is abnormally expressed in diffuse cutaneous systemic sclerosis skin and mediates myeloid cell adhesion., Y Hou, B J Rabquer, M L Gerber, F Del Galdo, S A Jimenez, G K Haines, W G Barr, M C Massa, J R Seibold, and A E Koch

Manuscripts from 2009


Mechanism of NSF: New evidence challenging the prevailing theory, Ben B. Newton, PhD and Sergio A. Jimenez, MD


Osteoarthritis associated with estrogen deficiency., Jorge A Roman-Blas, Santos Castañeda, Raquel Largo, and Gabriel Herrero-Beaumont

Submissions from 2008


Caveolin-1, TGF-β receptor internalization, and the pathogenesis of systemic sclerosis, Francesco Del Galdo, Michael P. Lisanti, and Sergio A. Jimenez


Targeting NF-kappaB: a promising molecular therapy in inflammatory arthritis., Jorge A. Roman-Blas and Sergio A. Jimenez

Molecular ablation of TGF-beta signaling pathways by tyrosine kinase inhibition: The coming of a promising new era in the treatment of tissue fibrosis, Joel Rosenbloom and Sergio A. Jimenez

Documents from 2007

T cells expressing allograft inflammatory factor 1 display increased chemotaxis and induce a profibrotic phenotype in normal fibroblasts in vitro, Francesco Del Galdo and Sergio A. Jimenez

Regulation of the human SOX9 promoter by Sp1 and CREB, Sonsoles Piera-Velazquex, David F. Hawkins, Mary Kate Whitecavage, David C. Colter, Sergio A. Jimenez, and David A. Stokes

Modulation of TGF-β signaling by proinflammatory cytokines in articular chondrocytes, J A. Roman-Blas, D G. Stokes, and S. A. Jimenez

Documents from 2006

The role of allograft inflammatory factor 1 in systemic sclerosis, Francesco Del Galdo, Carol M. Artlett, and Sergio A. Jimenez

Expression of allograft inflammatory factor 1 in tissues from patients with systemic sclerosis and in vitro differential expression of its isoforms in response to transforming growth factor beta, Francesco Del Galdo, Gerd G. Maul, Sergio A. Jimenez, and Carol M. Artlett

Inhibition of systemic sclerosis dermal fibroblast type I collagen production and gene expression by simvastatin, Natalia Louneva, Gonzalo Huaman, Joanna Fertala, and Sergio A. Jimenez

Description of twelve cases of nephrogenic fibrosing dermopathy and review of the literature, Fabian A. Mendoza, Carol M. Artlett, Nora Sandorfi, Kevin Latinis, Sonoles Piera-Velazquez, and Sergio A. Jimenez

Documents from 2005

Inhibition of Collagen Gene Expression in Systemic Sclerosis Dermal Fibroblasts by Mithramycin, Nora Sandorfi, Natalia Louneva, Elena Hitraya, Gyorgy Hajnoczky, Biagio Saitta, and Sergio A. Jimenez

Documents from 2004


B-Myb acts as a repressor of human COL1A1 collagen gene expression by interacting with Sp1 and CBF factors in scleroderma fibroblasts, Lucia Cicchillitti, Sergio A. Jimenez, Arturo Sala, and Biaggio Saitta

Following the molecular pathways toward an understanding of the pathogenesis of systemic sclerosis, Chris T. Derk and Sergio A. Jimenez

Dialysis-associated systemic fibrosis (nephrogenic fibrosing dermopathy): study of inflammatory cells and transforming growth factor beta1 expression in affected skin, Sergio A. Jimenez, Carol M. Artlett, Nora Sandorfi, Chris T. Derk, Kevin Latinis, Heloisa Sawaya, Richard Haddad, and Joseph C. Shanahan

Documents from 2002

Inhibition of basal and transforming growth factor-beta-induced stimulation of COL1A1 transcription by the DNA intercalators, mitoxantrone and WP631, in cultured human dermal fibroblasts, Svetlana Gaidarova and Sergio A. Jimenez

Documents from 2001


Role of protein kinase C-delta in the regulation of collagen gene expression in scleroderma fibroblasts, Sergio A. Jimenez, Svetlana Gaidarova, Biagio Saitta, Nora Sandorfi, David J. Herrich, Joan C. Rosenbloom, Umberto Kucich, William R. Abrams, and Joel Rosenbloom


Regulation of type-II collagen gene expression during human chondrocyte de-differentiation and recovery of chondrocyte-specific phenotype in culture involves Sry-type high-mobility-group box (SOX) transcription factors, David G. Stokes, Gang Liu, Rita Dharmavaram, David Hawkins, Sonsoles Piera-Velazquez, and Sergio A. Jimenez

Documents from 2000

Detection of cellular microchimerism of male or female origin in systemic sclerosis patients by polymerase chain reaction analysis of HLA-Cw antigens, Carol M. Artlett, Lori A. Cox, and Sergio A. Jimenez

CCAAT binding transcription factor binds and regulates human COL1A1 promoter activity in human dermal fibroblasts: demonstration of increased binding in systemic sclerosis fibroblasts, Biagio Saitta, Svetlana Gaidarova, Lucia Cicchillitti, and Sergio A. Jimenez

Documents from 1999

Lack of endothelial cell apoptosis in the dermis of tight skin 1 and tight skin 2 mice, Roswitha Sgonc, Hermann Deitrich, Claudia Sieberer, Georg Wick, Paul J. Christner, and Sergio A. Jimenez

Documents from 1998

Modulation of basal expression of the human alpha1(I) procollagen gene (COL1A1) by tandem NF-1/Sp1 promoter elements in normal human dermal fibroblasts, Carol M. Artlett, Shu-Jen Chen, John Varga, and Sergio A. Jimenez


Identification of fetal DNA and cells in skin lesions from women with systemic sclerosis, Carol M. Artlett, J. Bruce Smith, and Sergio A. Jimenez

Identification of elements in the promoter region of the alpha1(I) procollagen gene involved in its up-regulated expression in systemic sclerosis, Elena G. Hitraya, John Varga, Carol M. Artlett, and Sergio A. Jimenez

Documents from 1997

Fetal-maternal HLA compatibility confers susceptibility to systemic sclerosis, Carol Artlett, Ken I. Welsh, Carol M. Black, and Sergio A. Jimenez

Documents from 1996

Transcriptional activation of the alpha 1(I) procollagen gene in systemic sclerosis dermal fibroblasts:. Role of intronic sequences., Elena G. Hitraya and Sergio A. Jimenez

Documents from 1995


Stimulation of alpha 1(I) procollagen gene expression in NIH-3T3 cells by the human T cell leukemia virus type 1 (HTLV-1) tax gene., E. Munoz, D. Suri, S. Amini, K. Khalili, and Sergio A. Jimenez

Documents from 1993


The tight skin mouse: demonstration of mutant fibrillin-1 production and assembly into abnormal microfibrils, Cay M. Kielty, Michael Raghunath, Linda D. Siracusa, Michael J. Sherratt, Reiner Peters, C. Adrian Shuttleworth, and Sergio A. Jimenez