Non-contrast MRI may predict safety of gadolinium-enhanced MRI in patients with cirrhosis

Authors

Jonathan M. Fenkel, MD, Division of Gastroenterology and Hpatology, Thomas Jefferson UniversityFollow
Colin L. Smith, MD, Department of Medicine, Thomas Jefferson UniversityFollow
Leela Nayak, MD, Department of Medicine, Thomas Jefferson UniversityFollow
Steven K. Herrine, MD, Division of Gastroenterology and Hpatology, Thomas Jefferson UniversityFollow
Donald G. Mitchell, MD, Department of Radiology, Thomas Jefferson University

Document Type

Poster

Publication Date

10-2010

Abstract

Background:

Hepatorenal syndrome (HRS) is a relative contraindication to receiving gadolinium-based contrast media secondary to risk of nephrogenic systemic fibrosis (NSF)

Patients with cirrhosis frequently undergo magnetic resonance imaging (MRI) for hepatocellular cancer screening and liver transplant evaluation.

Most centers require documented serum creatinine levels within 10-14 days of performing MRIs on patients with cirrhosis.

Ascites can be readily detected on MRI without contrast enhancement.

Objective:

To determine whether the presence of ascites on MRI can be used to recommend against a diagnosis of HRS without knowledge of a serum creatinine level.

Recommended Citation

Fenkel, MD, Jonathan M.; Smith, MD, Colin L.; Nayak, MD, Leela; Herrine, MD, Steven K.; and Mitchell, MD, Donald G., "Non-contrast MRI may predict safety of gadolinium-enhanced MRI in patients with cirrhosis" (2010). Division of Gastroenterology and Hepatology Faculty Papers. Paper 2.
https://jdc.jefferson.edu/gastro_hepfp/2