Document Type
Article
Publication Date
3-2025
Abstract
Septic arthritis caused by M. hominis is exceptionally rare. Here, we report on a 62-year-old man with a medical history of gout and renal cell carcinoma who presented with persistent knee pain and swelling following partial nephrectomy complicated by an abdominal abscess. Arthrocentesis revealed monosodium urate crystals, leading to the initial diagnosis and treatment of gouty arthritis using intra-articular steroid injections, allopurinol, and colchicine. Initial cultures yielded no growth. However, faint transparent colonies grew after discharge, which were eventually identified as M. hominis. Initial antibacterial therapy targeting suspect Mycoplasma spp. was begun with doxycycline, and the patient ultimately completed 12 weeks of doxycycline and clindamycin with cure. This case underscores the importance of maintaining clinical suspicion for fastidious organisms when faced with persistent clinical symptoms without an identifiable organism and highlights a rare clinical presentation of M. hominis.
Recommended Citation
Liddy, Angelina; Kramer, Carolyn; and Weber, Devin M., "Mycoplasma hominis–Associated Septic Arthritis Masquerading as Gouty Arthritis" (2025). Division of Infectious Diseases and Environmental Medicine Faculty Papers. Paper 19.
https://jdc.jefferson.edu/didem/19
Creative Commons License

This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.
Language
English


Comments
This article is the author’s final published version in Infectious Diseases in Clinical Practice, Volume 32, Issue 2, March 2025, Article number e1435.
The published version is available at https://doi.org/10.1097/IPC.0000000000001435. Copyright © 2024 The Author(s). Published by Wolters Kluwer Health, Inc.