Safety and Efficacy of Very High Dose Furosemide Continuous Infusions

Authors

Jessica Wilczynski, PharmD, Thomas Jefferson UniversityFollow
Matthew Decaro, MD, FACC, FACP, Thomas Jefferson UniversityFollow
Gregary Marhefka, MD, FACC, FACP, Thomas Jefferson UniversityFollow
Brandi Thoma, PharmD, BCPS, BCCP, Thomas Jefferson UniversityFollow
Susan Varghese, PharmD, BCPS, Thomas Jefferson UniversityFollow
Ryan Watson, MD, Thomas Jefferson UniversityFollow
Ilya Danelich, PharmD, BCPS, BCCP, Thomas Jefferson UniversityFollow

Files

Description

• Fluid overload is treated with loop diuretics in patients with heart failure and in patients with acute kidney injury1,2
• There are sparse data regarding use of very high dose continuous loop diuretic infusions. In some studies, very high doses were only used in outlying patients (maximum160 mg/hour)3, 4
• The use of very high dose furosemide continuous infusions at Thomas Jefferson University Hospital is a rare practice. These infusions range in dose from 40-240 mg/hour, with no limitation on the duration
• The purpose of this study is to examine the efficacy and safety of very high dose furosemide continuous infusions

Publication Date

3-14-2019

Keywords

safety, high dose furosemide, continuous infusion

Disciplines

Cardiology | Medicine and Health Sciences | Pharmacy and Pharmaceutical Sciences

Comments

Presented at the 2019 American College of Cardiology Annual Meeting

Recommended Citation

Wilczynski, PharmD, Jessica; Decaro, MD, FACC, FACP, Matthew; Marhefka, MD, FACC, FACP, Gregary; Thoma, PharmD, BCPS, BCCP, Brandi; Varghese, PharmD, BCPS, Susan; Watson, MD, Ryan; and Danelich, PharmD, BCPS, BCCP, Ilya, "Safety and Efficacy of Very High Dose Furosemide Continuous Infusions" (2019). Division of Cardiology Posters. 3.
https://jdc.jefferson.edu/cardiologyposters/3