My major research interests include:

1. Mechanisms and regulation of insulin receptor signal transduction.
2. Protein-tyrosine phosphatases and the regulation of hormone action.
3. Pathophysiology of insulin-resistant disease states including obesity and Type 2 diabetes mellitus.
4. Mechanisms of the complications of diabetes, including vascular signaling by adiponectin.

Department of Medicine Faculty Papers

• Raogo Ouedraogo, Yulan Gong, Brett Berzins, Xiandong Wu, Kalyankar Mahadev, Kelly Hough, Lawrence Chan, Barry J. Goldstein, and Rosario Scalia (2007) Adiponectin deficiency increases leukocyte-endothelium interactions via upregulation of endothelial cell adhesion molecules in vivo
• Kalyankar Mahadev, Hiroyuki Motoshima, Xiangdong Wu, Jean Marie Ruddy, Rebecca S. Arnold, Guangjie Cheng, J. David Lambeth, and Barry J. Goldstein (2004) The NAD(P)H oxidase homolog Nox4 modulates insulin-stimulated generation of H₂0₂ and plays an integral role in insulin signal transduction
• Wei-Ren Zhang, Naotake Hashimoto, Faiyaz Ahmad, Wendi Ding, and Barry J. Goldstein (1994) Molecular cloning and expression of a unique receptor-like protein-tyrosine-phosphatase in the leucocyte-common-antigen-related phosphatase family
• Barry J. Goldstein and James N. Livingston (1980) Insulin degradation by adipose tissue. Studies at several levels of cellular organization
• Barry J. Goldstein and Stanley A. Zahler (1976) Uptake of branched-chain alpha-keto acids in Bacillus subtilis