Primary CNS lymphoma (PCNSL) is a rare type of diffuse large B-cell lymphoma (DLBCL) arising from and usually confined to CNS. Understating of the pathogenesis and prognostic markers is a challenge due to rarity of this neoplasm and paucity of the material available to study. Recent studies have shown that dual expression of MYC and BCL2 in DLBCL contributes to inferior overall survival. The prognostic value of MYC and BCL2 in PCNSL is not well studied.
Recommended CitationUppal, MD, Guldeep; Wang, PhD, Zi-Xuan (Zoe); Bajaj, PhD, Renu; Curtis, MD, PhD, Mark T.; Solomides, MD, Charalambos C.; Glass, MD, Jon; Banks, Peter M.; Peiper, MD, Stephen C.; and Gong, MD, Jerald Z., "BCL2 Expression and BCL2/MYC Dual Expression Predicts Inferior Survival in Primary Central Nervous System Lymphoma" (2014). Pathology, Anatomy and Cell Biology Resident's Posters. Paper 5.