An Assessment of the Reliability of Platelet-Associated Flags Generated by the Sysmex XE-5000 Automated Hematology Analyzer in Detecting Platelet Clumps

Authors

Jennifer M. Hawkins, DO, Thomas Jefferson UniversityFollow
Gene Gulati, Ph.D, Department of Pathology, Anatomy, and Cell Biology, Jefferson Medical College of Thomas Jefferson University, Philadelphia, PAFollow
Guldeep Uppal, MD, Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson UniversityFollow
Jerald Z. Gong, MD, Thomas Jefferson UniversityFollow

Document Type

Poster

Publication Date

4-20-2015

Abstract

Background

XE-5000 is an automated hematology analyzer utilized by clinical laboratories worldwide to perform CBC and differential leukocyte counts on EDTA-anticoagulated blood specimens. The overall reliability of the results generated by this analyzer has been assessed and found acceptable for clinical use. The CBC results generated on some of the blood specimens are, however, flagged by the analyzer for verification of the result of the flagged parameter by other means. One such parameter of clinical significance is the automated platelet count, which is often unreliable if the blood specimen contains platelet clumps.

Recommended Citation

Hawkins, DO, Jennifer M.; Gulati, Ph.D, Gene; Uppal, MD, Guldeep; and Gong, MD, Jerald Z., "An Assessment of the Reliability of Platelet-Associated Flags Generated by the Sysmex XE-5000 Automated Hematology Analyzer in Detecting Platelet Clumps" (2015). Department of Pathology, Anatomy, and Cell Biology Faculty Papers. Paper 163.
https://jdc.jefferson.edu/pacbfp/163